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https://www.readbyqxmd.com/read/29031236/inhibitory-effect-of-probiotic-lactobacilli-supernatants-on-single-and-mixed-non-albicans-candida-species-biofilm
#1
Yulong Tan, Matthias Leonhard, Doris Moser, Su Ma, Berit Schneider-Stickler
OBJECTIVES: Oral candidiasis is one of the most common human fungal infections. While most cases of the Candida species isolated from the oral cavity are Candida albicans, a large number of candidiasis is attributed to non-albicans Candida species. In this study, we aim to evaluate the in vitro inhibition of supernatants of Lactobacillus gasseri and Lactobacillus rhamnosus on the single and mixed species biofilm of non-albicans Candida species, including Candida tropicalis, Candida krusei and Candida parapsilosis...
October 6, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29029282/ecoinformatics-can-infer-causal-effects-of-crop-variety-on-insect-attack-by-capitalizing-on-pseudoexperiments-created-when-different-crop-varieties-are-interspersed-a-case-study-in-almonds
#2
Jay A Rosenheim, Bradley S Higbee, Jonathan D Ackerman, Matthew H Meisner
Capturing the complementary strengths of observational and experimental research methods usually requires the researcher to gather separate experimental and observational data sets. In some cases, however, commercial agricultural practices produce the spatial and temporal mixing of 'treatments' independently of other possibly covarying factors that is normally achieved only with formal experimentation. The resulting 'pseudoexperiments' can provide strong evidence for causal relationships. Here, we analyze a large observational data set that creates a series of such pseudoexperiments to assess the effect of different commercial varieties of almond, Prunus dulcis (Mill...
September 27, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29029280/pharmacokinetics-and-safety-results-from-the-phase-3-randomized-open-label-study-of-intravenous-posaconazole-in-patients-at-risk-of-invasive-fungal-disease
#3
Oliver A Cornely, Michael N Robertson, Shariq Haider, Andrew Grigg, Michelle Geddes, Mickael Aoun, Werner J Heinz, Issam Raad, Urs Schanz, Ralf G Meyer, Sarah P Hammond, Kathleen M Mullane, Helmut Ostermann, Andrew J Ullmann, Stefan Zimmerli, M L P S Van Iersel, Deborah A Hepler, Hetty Waskin, Nicholas A Kartsonis, Johan Maertens
No abstract text is available yet for this article.
October 3, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29029265/preclinical-testing-of-a-broad-spectrum-antimicrobial-endotracheal-tube-coated-with-an-innate-immune-synthetic-mimic
#4
Marjan M Hashemi, John Rovig, Jordan Bateman, Brett S Holden, Tomasz Modelzelewski, Iliana Gueorguieva, Martin von Dyck, Ronald Bracken, Carl Genberg, Shenglou Deng, Paul B Savage
Background: Endotracheal tubes provide an abiotic surface on which bacteria and fungi form biofilms, and the release of endotoxins and planktonic organisms can cause damaging inflammation and infections. Objectives: Ceragenins are small molecule mimics of antimicrobial peptides with broad-spectrum antibacterial and antifungal activity, and a ceragenin may be used to provide antimicrobial protection to the abiotic surface of an endotracheal tube. Methods: A hydrogel film, containing CSA-131, was generated on endotracheal tubes...
October 4, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29029118/potential-side-effects-of-the-entomopathogenic-fungus-metarhizium-anisopliae-on-the-egg-parasitoid-trichogramma-pretiosum-hymenoptera-trichogrammatidae-under-controlled-conditions
#5
M Potrich, L F A Alves, E R Lozano, A K Bonini, P M O J Neves
The purpose was to evaluate the side effects of strains Metarhizium anisopliae (Metsch.) Sorokin sensu lato Unioeste 43 and M. anisopliae sensu stricto ESALQ 1641 on Trichogramma pretiosum Riley (Hymenoptera: Trichogrammatidae) under controlled conditions. A free-choice test for parasitism was performed, with the confinement of T. pretiosum females mated with cards (1 × 5 cm) containing age-standardized Anagasta kuehniella Zeller eggs, either sprayed with a fungal strain (109 conidia/ml) or 0.01% v/v Tween 80 (control)...
October 6, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29029010/call-for-action-invasive-fungal-infections-associated-with-ibrutinib-and-other-small-molecule-kinase-inhibitors-targeting-immune-signaling-pathways
#6
Georgios Chamilos, Michail S Lionakis, Dimitrios P Kontoyiannis
Opportunistic infections caused by Pneumocystis jirovecii, Cryptococcus neoformans, and ubiquitous airborne filamentous fungi have been recently reported in patients with hematological cancers historically considered at low risk for invasive fungal infections (IFIs), after receipt of the Bruton tyrosine kinase inhibitor ibrutinib. The spectrum and severity of IFIs often observed in these patients implies the presence of a complex immunodeficiency that may not be solely attributed to mere inhibition of Bruton tyrosine kinase...
September 27, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29028668/the-mycobiome-in-hiv
#7
Christopher L Hager, Mahmoud A Ghannoum
PURPOSE OF REVIEW: There are a limited number of studies investigating the association between the microbiome and HIV. Although the majority of these published investigations have focused on the role of the bacterial community (bacteriome) in this setting, a handful of studies have also characterized the role of the mycobiome in HIV-infected individuals. This review will summarize the most recent reports pertaining to the role of the fungal community in HIV. RECENT FINDINGS: Differences in the composition of the oral and respiratory mycobiome in HIV-infected individuals compared with uninfected individuals have been reported...
October 11, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/29028545/penicillium-expansum-compatible-and-penicillium-digitatum-non-host-pathogen-infection-differentially-alter-ethylene-biosynthesis-in-apple-fruit
#8
Laura Vilanova, Núria Vall-Llaura, Rosario Torres, Josep Usall, Neus Teixidó, Christian Larrigaudière, Jordi Giné-Bordonaba
The role of ethylene on inducing plant resistance or susceptibility to certain fungal pathogens clearly depends on the plant pathogen interaction with little or no-information available focused on the apple-Penicillium interaction. Taken advantage that Penicillium expansum is the compatible pathogen and P. digitatum is the non-host of apples, the present study aimed at deciphering how each Penicillium spp. could interfere in the fruit ethylene biosynthesis at the biochemical and molecular level. The infection capacity and different aspects related to the ethylene biosynthesis were conducted at different times post-inoculation...
September 30, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29028001/soil-protist-communities-form-a-dynamic-hub-in-the-soil-microbiome
#9
Wu Xiong, Alexandre Jousset, Sai Guo, Ida Karlsson, Qingyun Zhao, Huasong Wu, George A Kowalchuk, Qirong Shen, Rong Li, Stefan Geisen
Soil microbes are essential for soil fertility. However, most studies focus on bacterial and/or fungal communities, while the top-down drivers of this microbiome composition, protists, remain poorly understood. Here, we investigated how soil amendments affect protist communities and inferred potential interactions with bacteria and fungi. Specific fertilization treatments impacted both the structure and function of protist communities. Organic fertilizer amendment strongly reduced the relative abundance of plant pathogenic protists and increased bacterivorous and omnivorous protists...
October 13, 2017: ISME Journal
https://www.readbyqxmd.com/read/29028000/influence-of-resistance-breeding-in-common-bean-on-rhizosphere-microbiome-composition-and-function
#10
Lucas William Mendes, Jos M Raaijmakers, Mattias de Hollander, Rodrigo Mendes, Siu Mui Tsai
The rhizosphere microbiome has a key role in plant growth and health, providing a first line of defense against root infections by soil-borne pathogens. Here, we investigated the composition and metabolic potential of the rhizobacterial community of different common bean (Phaseolus vulgaris) cultivars with variable levels of resistance to the fungal root pathogen Fusarium oxysporum (Fox). For the different bean cultivars grown in two soils with contrasting physicochemical properties and microbial diversity, rhizobacterial abundance was positively correlated with Fox resistance...
October 13, 2017: ISME Journal
https://www.readbyqxmd.com/read/29027734/high-resolution-visualization-and-exo-proteomics-reveal-the-physiological-role-of-xlnr-and-arar-in-plant-biomass-colonization-and-degradation-by-aspergillus-niger
#11
Joanna E Kowalczyk, Claire Khosravi, Samuel Purvine, Alice Dohnalkova, William B Chrisler, Galya Orr, Errol Robinson, Erika Zink, Ad Wiebenga, Mao Peng, Evy Battaglia, Scott Baker, Ronald P de Vries
In A. niger, two transcription factors, AraR and XlnR, regulate the production of enzymes involved in degradation of arabinoxylan and catabolism of the released L-arabinose and D-xylose. Deletion of both araR and xlnR in leads to reduced production of (hemi)cellulolytic enzymes and reduced growth on arabinan, arabinogalactan and xylan. In this study we investigated the colonization and degradation of wheat bran by the A. niger reference strain CBS 137562 and araR/xlnR regulatory mutants using high-resolution microscopy and exo-proteomics...
October 13, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/29027707/a-trichosporonales-genome-tree-based-on-27-haploid-and-three-evolutionarily-conserved-natural-hybrid-genomes
#12
Masako Takashima, Sira Sriswasdi, Ri-Ichiroh Manabe, Moriya Ohkuma, Takashi Sugita, Wataru Iwasaki
To construct a backbone tree consisting of basidiomycetous yeasts, draft genome sequences from 25 species of Trichosporonales (Tremellomycetes, Basidiomycota) were generated. In addition to the hybrid genomes of Trichosporon coremiiforme and T. ovoides that we described previously, we identified an interspecies hybrid genome in Cutaneotrichosporon mucoides (formerly T. mucoides). This hybrid genome had a gene retention rate of approximately 55%, and its closest haploid relative was C. dermatis. After constructing the C...
October 13, 2017: Yeast
https://www.readbyqxmd.com/read/29027475/antimould-microbial-and-plant-metabolites-with-potential-use-in-intelligent-food-packaging
#13
Francesca Valerio, Marco Masi, Alessio Cimmino, Seyed Arash Moeini, Paola Lavermicocca, Antonio Evidente
Moulds food infestation is a heavy dangerous problem for human health and also could generate heavy economic losses. The intelligent packaging using eco-friendly biodegradable biofilm incorporating bioactive natural safe compounds represents a new frontier. This manuscript reports the inhibitory activity of 12 bacterial, fungal and plant metabolites against Penicillium roqueforti and Aspergillus niger. Among them α-costic acid and ungeremine (3 and 12) are the most promising as potential biofungicide against both fungal strains...
October 13, 2017: Natural Product Research
https://www.readbyqxmd.com/read/29027474/on-the-metabolites-produced-by-colletotrichum-gloeosporioides-a-fungus-proposed-for-the-ambrosia-artemisiifolia-biocontrol-spectroscopic-data-and-absolute-configuration-assignment-of-colletochlorin-a
#14
Marco Masi, Maria Chiara Zonno, Alessio Cimmino, Pierluigi Reveglia, Alexander Berestetskiy, Angela Boari, Maurizio Vurro, Antonio Evidente
Ambrosia artemisiifolia L. is responsible for serious allergies induced on humans. Different approaches for its control were proposed during the COST Action FA1203 "Sustainable management of Ambrosia artemisiifolia in Europe" (SMARTER). Fungal secondary metabolites often show potential herbicidal activity. Three phytotoxins were purified from the fungal culture filtrates of Colletotrichum gloeosporioides, isolated from infected leaves of A. artemisiifolia. They were identified by spectroscopic and chemical methods as colletochlorin A, orcinol and tyrosol (1, 2 and 3)...
October 13, 2017: Natural Product Research
https://www.readbyqxmd.com/read/29027030/diagnostic-accuracy-of-fungal-identification-in-histopathology-and-cytopathology-specimens
#15
V L Kung, R D Chernock, C-A D Burnham
Tools to diagnose fungal infection are microscopic examination, antigen or antibody-based detection tests, molecular diagnostics, and culture, with culture being the "gold standard" for species-level identification. Although these methods are commonly used in concert and yield concordant results, in some cases tissue is not available for culture, and/or different methodologies yield discrepant results. These discrepancies may be clinically significant, causing confusion and inappropriate or delayed initiation of antifungals...
October 13, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29026931/imaging-patterns-of-rhino-orbital-cerebral-mucormycosis-in-immunocompromised-patients-when-to-suspect-complicated-mucormycosis
#16
Peter Raab, Ludwig Sedlacek, Stefanie Buchholz, Stefan Stolle, H Lanfermann
PURPOSE: The aim of this study was to describe radiological imaging findings of a complicated sinusitis, which should raise the suspicion of rhino-orbital-cerebral mucormycosis as being the underlying cause. METHODS: In this retrospective analysis, we describe the cases and imaging findings of 8 patients with proven mucormycosis. These patients presented mostly with new facial or orbital swelling and were referred for imaging to our institution. Magnetic resonance imaging and computed tomography images were classified as abnormal or normal with respect to orbital, paranasal and cerebral signal results...
October 12, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/29026829/aggressive-combined-medical-and-surgical-management-of-mucormycosis-results-in-disease-eradication-in-2-pediatric-patients
#17
Haley F M Augustine, Colin White, James Bain
Rhinocerebral mucormycosis is an acute, rapidly fatal, fungal infection, classically involving the nasal mucosa and paranasal sinuses. It is an aggressive, opportunistic infection that frequently progresses to involve the orbit and cerebrum. Cerebral extension in immunocompromised patients is almost universally fatal. There are limited data on mucormycosis in pediatric immunocompromised patients in the literature, with only few reports on rhinocerebral involvement. The immunocompromised patients described in this report presented with suspected periorbital and nasal cellulitis, progressing rapidly to necrotic changes in nasal tissue and oral palatal mucosa...
August 2017: Plastic Surgery
https://www.readbyqxmd.com/read/29026629/a-case-of-exophiala-dermatitidis-infection-in-a-child-after-allogeneic-stem-cell-transplantation-case-report-and-literature-review-of-paediatric-cases
#18
Dominika Tanuskova, Julia Horakova, Darina Buzassyova, Miroslava Poczova, Ivana Bodova, Peter Svec, Alica Chocholova, Jaroslava Adamcakova, Tomas Sykora, Miroslava Pozdechova, Lucia Geczova, Alexandra Kolenova
Introduction.Exophiala dermatitidisis a relatively common environmental black yeast with worldwide distribution and is a rare cause of fungal infection, mostly in patients with certain predisposing factors. Due to the rarity of the infection, little is known about the specific predisposing factors, way of infection or treatment. Case presentation. Here, we report what is to our knowledge the first case of E. dermatitidis infection in a child after allogeneic stem cell transplantation. We also review all paediatric cases reported in the literature since 1993...
June 2017: JMM Case Reports
https://www.readbyqxmd.com/read/29026628/cutaneous-fungal-infection-in-an-immunocompromised-host
#19
David Sotello, Mark Cappel, Tamara Huff, Diana Meza, Salvador Alvarez, Claudia R Libertin
No abstract text is available yet for this article.
June 2017: JMM Case Reports
https://www.readbyqxmd.com/read/29026627/marked-peripheral-eosinophilia-due-to-prolonged-administration-of-posaconazole
#20
Maher Alharbi, Rae-Kiran Jhinger, Terence Wuerz, Andrew Walkty
Introduction. Posaconazole is a triazole antifungal that is used in the treatment of a variety of fungal infections, as well as in the management of mucormycosis (on an off-label basis). Eosinophilia associated with exposure to azole antifungals has been described rarely in the literature. Case presentation. A 31-year-old male on peritoneal dialysis (PD) for end-stage renal disease, secondary to diabetic nephropathy, presented to hospital with abdominal pain after a trip to St Lucia. He was taken to the operating room, where the PD catheter was removed and an abdominal-wall abscess was debrided...
June 2017: JMM Case Reports
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