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https://www.readbyqxmd.com/read/28231704/genetic-correlations-between-behavioural-responses-and-performance-traits-in-laying-hens
#1
Iwona Rozempolska-Rucińska, Grzegorz Zięba, Lucyna Kibała, Tomasz Paweł Próchniak, Marek Łukaszewicz
The aim of the study was to evaluate genetic correlations between the behavioural profile and performance in laying hens as an indirect answer to the question whether the observed behavioural responses are associated with increased levels of stress in these birds. The assessment of birds' temperament was carried out using the Novel Objects Test. The behavioural test was conducted in two successive generations comprising 9483 Rhode Island White birds (approx. 4700 individuals per generation) and 4326 Rhode Island Red birds (approx...
February 23, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28231476/evaluation-of-cognitive-performance-in-professional-divers-by-means-of-event-related-potentials-and-neuropsychology
#2
Mehmet Ergen, Atilla Uslu, Ozlem Caglar, Sukriye Akca-Kalem, Maide Cimsit, Hakan Gurvit
OBJECTIVE: We investigated whether professional air diving with no decompression illness causes any long-term changes in cognitive functions. METHODS: The all-male participants consisted of 18 healthy control (HC) volunteers and 32 divers. Divers were divided into two subgroups as moderate exposure group, Divers-I (DI) and extensive exposure group, Divers-II (DII). Participants were administered a comprehensive neuropsychological battery and event-related potentials (ERPs) were recorded while they performed auditory oddball task and visual continuous performance test (CPT)...
January 29, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28230645/clinical-scale-rapid-autologous-bk-virus-specific-t-cell-line-generation-from-kidney-transplant-recipients-with-active-viremia-for-adoptive-immunotherapy
#3
Caroline Lamarche, Julie Orio, Victoria Georges-Tobar, Thomas Pincez, Mathieu Goupil, Amina Dahmani, Cedric Carli C, Ann Brasey, Lambert Busque, Jean-Sébastien Delisle
BACKGROUND: Polyomavirus-associated nephropathy (PVAN) following BK virus reactivation in kidney transplant recipients (KTR) can compromise graft survival. Lowering immunosuppression is the only established approach to prevent or treat PVAN but nonspecifically increasing host immune competence also augments rejection risk. Ex vivo T cell stimulation/expansion offers the possibility to generate BK-specific T cell lines for adoptive immunotherapy. The objective of this study was to develop and characterize a clinical scale protocol to generate BK-specific T cell lines from viremic KTR...
February 23, 2017: Transplantation
https://www.readbyqxmd.com/read/28230201/relapsing-remitting-multiple-sclerosis-patients-display-an-altered-lipoprotein-profile-with-dysfunctional-hdl
#4
Winde Jorissen, Elien Wouters, Jeroen F Bogie, Tim Vanmierlo, Jean-Paul Noben, Denis Sviridov, Niels Hellings, Veerle Somers, Roland Valcke, Bart Vanwijmeersch, Piet Stinissen, Monique T Mulder, Alan T Remaley, Jerome J A Hendriks
Lipoproteins modulate innate and adaptive immune responses. In the chronic inflammatory disease multiple sclerosis (MS), reports on lipoprotein level alterations are inconsistent and it is unclear whether lipoprotein function is affected. Using nuclear magnetic resonance (NMR) spectroscopy, we analysed the lipoprotein profile of relapsing-remitting (RR) MS patients, progressive MS patients and healthy controls (HC). We observed smaller LDL in RRMS patients compared to healthy controls and to progressive MS patients...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28229986/executive-function-training-for-children-with-attention-deficit-hyperactivity-disorder
#5
Lan Shuai, David Daley, Yu-Feng Wang, Jin-Song Zhang, Yan-Ting Kong, Xin Tan, Ning Ji
BACKGROUND: Accumulating evidence indicates that attention deficit hyperactivity disorder (ADHD) is associated with core deficits in executive function (EF) which predicts poorer academic and occupational functioning. This makes early intervention targeting EF impairments important to prevent long-term negative outcomes. Cognitive training is a potential ADHD treatment target. The present study aimed to explore the efficacy, feasibility, and acceptability of a cognitive training program (targeting child's multiple EF components and involving parent support in daily life), as a nonpharmacological intervention for children with ADHD...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28227399/functional-connectivity-analysis-using-whole-brain-and-regional-network-metrics-in-ms-patients
#6
V C Chirumamilla, V Fleischer, A Droby, T Anjum, M Muthuraman, F Zipp, S Groppa, V C Chirumamilla, V Fleischer, A Droby, T Anjum, M Muthuraman, F Zipp, S Groppa, A Droby, S Groppa, F Zipp, V C Chirumamilla, T Anjum, V Fleischer, M Muthuraman
In the present study we investigated brain network connectivity differences between patients with relapsing-remitting multiple sclerosis (RRMS) and healthy controls (HC) as derived from functional resonance magnetic imaging (fMRI) using graph theory. Resting state fMRI data of 18 RRMS patients (12 female, mean age ± SD: 42 ± 12.06 years) and 25 HC (8 female, 29.2 ± 5.38 years) were analyzed. In order to obtain information of differences in entire brain network, we focused on both, local and global network connectivity parameters...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226869/the-long-range-temporal-correlations-of-broadband-eeg-oscillations-in-poststroke-depression-subjects-with-basal-ganglia-infarction
#7
Chunfang Wang, Jingang Du, Ying Zhang, Peng Zhou, Dong Ming, Chunfang Wang, Jingang Du, Ying Zhang, Peng Zhou, Dong Ming, Jingang Du, Peng Zhou, Chunfang Wang, Ying Zhang, Dong Ming
Recent studies have found long-range temporal correlations (LRTC) of neuronal oscillation under different physiological and pathological state. In this paper we aimed to explore the temporal correlations of broadband neuronal oscillation in poststroke depression. Resting state EEGs of 16 electrodes in 16 poststroke depression (PSD), 18 poststroke non-depression (PSND) and 18 healthy control (HC) subjects were analyzed by means of detrended fluctuation analysis (DFA), a quantitative measurement of LRTC. The results indicated that LRTC of broadband oscillation in PSD subjects was still preserved and had similar spatial distribution to non-depression subjects, but attenuated especially in left hemisphere and frontal and posterior temporal regions of right hemisphere...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225958/recurrence-rate-of-basal-cell-carcinoma-with-positive-histopathological-margins-and-related-risk-factors
#8
Fernanda Lara, Jesus Rodriguez Santamaría, Luiz Eduardo Fabricio de Melo Garbers
BACKGROUND: The best way to approach surgically removed basal cell carcinoma with positive histopathological margins is a controversial issue. Some authors believe that the more appropriate treatment is an immediate reoperation while others prefer a periodic follow up. The rates of recurrence are variable in literature, between 10% and 67%. OBJECTIVE: To define the recurrence rate of basal cell carcinoma with positive margins after surgery. Secondarily, identify morphological aspects that can suggest a more frequent tumoral recurrence...
January 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28224080/brain-activation-to-task-irrelevant-disorder-related-threat-in-social-anxiety-disorder-the-impact-of-symptom-severity
#9
Carina Yvonne Heitmann, Katharina Feldker, Paula Neumeister, Leonie Brinkmann, Elisabeth Schrammen, Pienie Zwitserlood, Thomas Straube
Unintentional and uncontrollable processing of threat has been suggested to contribute to the pathology of social anxiety disorder (SAD). The present study investigated the neural correlates of processing task-irrelevant, highly ecologically valid, disorder-related stimuli as a function of symptom severity in SAD. Twenty-four SAD patients and 24 healthy controls (HC) performed a feature-based comparison task during functional magnetic resonance imaging, while task-irrelevant, disorder-related or neutral scenes were presented simultaneously at a different spatial position...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28223872/chitosan-treatment-abrogates-hypercholesterolemia-induced-erythrocyte-s-arginase-activation
#10
Gamaleldin I Harisa, Sabry M Attia, Khairy M A Zoheir, Fars K Alanazi
This study aimed to evaluate the protective effect of chitosan (CS) against hypercholesterolemia (HC) induced arginase activation and disruption of nitric oxide (NO) biosynthesis using erythrocytes as cellular model. Human erythrocytes were isolated and classified into eight groups. Next, cells were treated with l-arginine (l-ARG), N(ω)-nitro-l-arginine methyl ester (l-NAME), CS or CS + l-ARG in the presence of normal plasma or cholesterol enriches plasma. Then, erythrocytes were incubated at 37 °C for 24 h...
January 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28223840/gross-and-fine-motor-function-in-fibromyalgia-and-chronic-fatigue-syndrome
#11
Omid Rasouli, Egil A Fors, Petter Chr Borchgrevink, Fredrik Öhberg, Ann-Katrin Stensdotter
PURPOSE: This paper aimed to investigate motor proficiency in fine and gross motor function, with a focus on reaction time (RT) and movement skill, in patients with fibromyalgia (FM) and chronic fatigue syndrome (CFS) compared to healthy controls (HC). METHODS: A total of 60 individuals (20 CFS, 20 FM, and 20 HC), age 19-49 years, participated in this study. Gross motor function in the lower extremity was assessed using a RT task during gait initiation in response to an auditory trigger...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28222705/orthorexia-and-anorexia-nervosa-two-distinct-phenomena-a-cross-cultural-comparison-of-orthorexic-behaviours-in-clinical-and-non-clinical-samples
#12
C Gramaglia, A Brytek-Matera, R Rogoza, P Zeppegno
BACKGROUND: Orthorexia nervosa (ON) is defined as pathological healthful eating. The aim of this study was to investigate whether there is any difference in orthorexic behaviours between clinical and non-clinical groups, and in different cultural contexts. . METHODS: Recruitment involved both female patients with anorexia nervosa (AN) and healthy controls (HC) from Italy and Poland (N = 23 and N = 35 AN patients; and N = 39 and N = 39 HCs, in Italy and Poland, respectively)...
February 21, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28220291/efficacy-of-mastoid-oscillation-and-the-gufoni-maneuver-for-treating-apogeotropic-horizontal-benign-positional-vertigo-a-randomized-controlled-study
#13
Hyun Ah Kim, Sang-Won Park, Jungil Kim, Bong-Gu Kang, Jun Lee, Byung In Han, Jung Im Seok, Eun-Ji Chung, Jaeyoung Kim, Hyung Lee
: To determine the immediate and short-term efficacies of mastoid oscillation vs. Gufoni maneuver in treating the apogeotropic type of horizontal canal benign paroxysmal positional vertigo (HC-BPPV), we designed a randomized, prospective, sham-controlled study. In eight dizziness clinics in Korea, 209 consecutive patients with apogeotropic HC-BPPV were enrolled. The patients were randomly assigned to receive a single application of Gufoni (n = 70), mastoid oscillation (n = 67), or sham maneuver (n = 72)...
February 20, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28220069/effects-of-selective-serotonin-reuptake-inhibitors-on-interregional-relation-of-serotonin-transporter-availability-in-major-depression
#14
Gregory M James, Pia Baldinger-Melich, Cecile Philippe, Georg S Kranz, Thomas Vanicek, Andreas Hahn, Gregor Gryglewski, Marius Hienert, Marie Spies, Tatjana Traub-Weidinger, Markus Mitterhauser, Wolfgang Wadsak, Marcus Hacker, Siegfried Kasper, Rupert Lanzenberger
Selective serotonin reuptake inhibitors (SSRIs) modulate serotonergic neurotransmission by blocking reuptake of serotonin from the extracellular space. Up to now, it remains unclear how SSRIs achieve their antidepressant effect. However, task-based and resting state functional magnetic resonance imaging studies, have demonstrated connectivity changes between brain regions. Here, we use positron emission tomography (PET) to quantify SSRI's main target, the serotonin transporter (SERT), and assess treatment-induced molecular changes in the interregional relation of SERT binding potential (BPND)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28219689/in-vitro-drug-release-profiles-of-ph-sensitive-hydroxyethylacryl-chitosan-sodium-alginate-hydrogels-using-paracetamol-as-a-soluble-model-drug
#15
Pitchaya Treenate, Pathavuth Monvisade
The aim of this study is to investigate in vitro drug release profiles of pH-sensitive hydrogels composed of hydroxyethylacryl chitosan (HC) and sodium alginate (SA). The hydrogels were crosslinked by dipping method using different ionic crosslinkers (e.g., Ca(2+), Zn(2+) and Cu(2+)). The crosslinking reaction was confirmed by FT-IR. Swelling behavior and stability of the hydrogels in simulated digestive media were investigated. The result indicated that the combination between HC and SA could delay the degradation time of the hydrogels...
February 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28219195/-expression-and-clinical-significance-of-semaphorin-3a-in-serum-and-mononuclear-cells-in-patients-with-systemic-lupus-erythematosus
#16
H Gao, X X Ma, Q Guo, Y D Zou, Y C Zhong, L F Xie, M Shao, X W Zhang
Objective: To determine the expression of Sema3A in serum and peripheral blood mononuclear cells (PBMC) of patients with systemic lupus erythematosus (SLE), to analysis the correlation of Sema3A expression and SLE clinical manifestations and laboratory indexes, and to evaluate the diagnostic value of Sema3A in patients with SLE. Methods: The concentration of serum Sema3A was detected by enzyme-linked immuno sorbent assay (ELISA) in patients with SLE, healthy controls (HC) and diseases controls. In addition, the mRNA expression level of Sema3A was examined in PBMC by real-time polymerase chain reaction...
February 7, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28217764/vpreb-serves-as-an-invariant-surrogate-antigen-for-selecting-immunoglobulin-antigen-binding-sites
#17
Mohamed Khass, Tessa Blackburn, Peter D Burrows, Mark R Walter, Emidio Capriotti, Harry W Schroeder
Developmental checkpoints eliminate B cells synthesizing defective immunoglobulin heavy (HC) and light (LC) chains. The first checkpoint tests for formation of a VpreB/λ5/µHC-containing preB-cell receptor (preBCR) and predicts whether µHCs will bind conventional LCs to form membrane IgM. VpreB and λ5 also create a sensing site that interacts with µHC antigen-binding region CDR-H3, but whether it plays a role in immunoglobulin repertoire selection and function is unknown. On a position-by-position basis, we analyzed the amino acid content of CDR-H3s from H chains cloned from living and apoptotic preB cells and from IgG:Antigen structures...
July 14, 2016: Science Immunology
https://www.readbyqxmd.com/read/28215897/effects-of-body-condition-monensin-and-essential-oils-on-ruminal-lipopolysaccharide-concentration-inflammatory-markers-and-endoplasmatic-reticulum-stress-of-transition-dairy-cows
#18
C Drong, S Bühler, J Frahm, L Hüther, U Meyer, D von Soosten, D K Gessner, K Eder, H Sauerwein, S Dänicke
Evidence exists that dairy cows experience inflammatory-like phenomena in the transition period. Rumen health and alterations in metabolic processes and gene networks in the liver as the central metabolic organ might be key factors for cows' health and productivity in early lactation. This study made use of an animal model to generate experimental groups with different manifestations of postpartal fat mobilization and ketogenesis. In total, 60 German Holstein cows were allocated 6 wk antepartum to 3 high-body condition score (BCS) groups (BCS 3...
February 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28215055/occupational-hazards-for-home-care-nurses-across-the-rural-to-urban-gradient-in-ontario-canada
#19
Matthew Wong, Margaret Saari, Erin Patterson, Martine Puts, Ann E Tourangeau
The purpose of this paper was to describe occupational hazards for nurses working in home care (HC) and explore how they differ across the rural-to-urban gradient. Responses (n = 823) from a cross-sectional survey conducted in 2012 of HC nurses registered to practise nursing in the Province of Ontario, Canada were used. Using chi-square analysis and posthoc pairwise tests with a Bonferroni correction, 14 occupational hazards were individually tested for differences between four geographical settings (rural, town, suburban or urban areas)...
February 19, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28214967/increased-atrial-%C3%AE-adrenergic-receptors-and-grk-2-gene-expression-can-play-a-fundamental-role-in-heart-failure-after-repair-of-congenital-heart-disease-with-cardiopulmonary-bypass
#20
Marcela Silva Oliveira, Fabio Carmona, Walter V A Vicente, Paulo H Manso, Karina M Mata, Mara Rúbia Celes, Erica C Campos, Simone G Ramos
Surgeries to correct congenital heart diseases are increasing in Brazil and worldwide. However, even with the advances in surgical techniques and perfusion, some cases, especially the more complex ones, can develop heart failure and death. A retrospective study of patients who underwent surgery for correction of congenital heart diseases with cardiopulmonary bypass (CPB) in a university tertiary-care hospital that died, showed infarction in different stages of evolution and scattered microcalcifications in the myocardium, even without coronary obstruction...
February 18, 2017: Pediatric Cardiology
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