Roberto Maglie, Simone Baldi, Giulia Nannini, Leandro Di Gloria, Marco Pallecchi, Gianluca Bartolucci, Matteo Ramazzotti, Elena Niccolai, Maria Efenesia Baffa, Biagioni Camilla, Farzan Solimani, Emiliano Antiga, Amedeo Amedei
Free fatty acids (FFA) have gained research interest owing to their functions in both local and systemic immune regulation. Changes in the serum levels of anti-inflammatory short chain fatty acids (SCFA), primarily derived from the gut microbiota, and pro-inflammatory medium (MCFA) and long (LCFA) chain fatty acids, derived from either the gut microbiota or the diet, have been associated with autoimmunity. Circulating FFA were retrospectively analysed by a gas chromatography-mass spectrometry method in the serum of 18 patients with pemphigus vulgaris (PV) at the baseline and 6 months (n = 10) after immunosuppressive treatments, and 18 healthy controls (HC)...
March 2024: Experimental Dermatology