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https://www.readbyqxmd.com/read/28433917/hydrothermal-carbonisation-of-poultry-litter-effects-of-initial-ph-on-yields-and-chemical-properties-of-hydrochars
#1
Bashir M Ghanim, Witold Kwapinski, James J Leahy
In this study, hydrothermal carbonisation (HTC) of poultry litter (PL) was carried out to evaluate the impact of initial pH using acetic acid (CH3COOH) or sulfuric acid (H2SO4) on the yields and properties of hydrochar (HC). The PL samples were treated by HTC at various initial pH and at 250°C for 2h. The HCs produced were characterized by ultimate, proximate and fibre analyses as well as heating value and surface area measurements. The results indicated that undertaking HTC in the presence of acids (CH3COOH, H2SO4) significantly affects the yields and properties of HC...
April 9, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28433542/blockade-of-pdgf-receptors-by-crenolanib-has-therapeutic-effect-in-patient-fibroblasts-and-in-preclinical-models-of-systemic-sclerosis
#2
Katsunari Makino, Tomoko Makino, Lukasz Stawski, Julio C Mantero, Robert Lafyatis, Robert Simms, Maria Trojanowska
Systemic sclerosis (SSc) is a multi-organ fibrotic disease with few treatment options. Activated fibroblasts are the key effector cells in SSc responsible for the excessive production of collagen and the development of fibrosis. PDGF, a potent mitogen for cells of mesenchymal origin, has been implicated in the activation of SSc fibroblasts. Our aim was to examine the therapeutic potential of crenolanib, an inhibitor of PDGF receptor signaling, in cultured fibroblasts and in angiotensin II (Ang II)-induced skin and heart fibrosis...
April 19, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28433021/to-kink-or-not-a-search-for-long-chain-cumulenones-using-microwave-spectral-taxonomy
#3
Michael C McCarthy, Luyao Zou, Marie-Aline Martin-Drumel
A systematic search for carbon-chain cumulenones beyond H2C4O has been undertaken using microwave spectral taxonomy in combination with a pulsed jet discharge source. No evidence was found for the C2υ isomer of H2C5O or its longer derivatives, but HC(O)C4H, the longer variant of propynal, HC(O)CCH, was identified instead. Its rotational and leading centrifugal distortion constants have been derived to high accuracy from detection of both a- and b-type lines; those below 40 GHz were measured using a Fabry-Perot cavity, while lines between 40 and 72 GHz were recorded by double resonance techniques...
April 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28432368/indoor-radon-in-micro-geological-setting-of-an-indigenous-community-in-canada-a-pilot-study-for-hazard-identification
#4
Atanu Sarkar, Derek Hc Wilton, Erica Fitzgerald
BACKGROUND: Radon is the second leading cause of lung cancer after smoking. In Canada, the health authorities have no access to comprehensive profile of the communities built over uranium-rich micro-geological settings. The present indoor radon monitoring guideline is unable to provide an accurate identification of health hazards due to discounting several parameters of housing characteristics. OBJECTIVE: To explore indoor radon levels in a micro-geological setting known for high uranium in bedrock and to develop a theoretical model for a revised radon testing protocol...
April 2017: International Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28432188/magnetic-resonance-neurography-visualizes-abnormalities-in-sciatic-and-tibial-nerves-in-patients-with-type-1-diabetes-and-neuropathy
#5
Michael Vaeggemose, Mirko Pham, Steffen Ringgaard, Hatice Tankisi, Niels Ejskjaer, Sabine Heiland, Per L Poulsen, Henning Andersen
This study evaluates whether diffusion-tensor-imaging MR-Neurography (DTI-MRN), T2-relaxation-time and proton-spin-density can detect and grade neuropathic abnormalities in patients with type 1 diabetes.Forty-nine patients with type 1 diabetes (11 with severe polyneuropathy (sDPN), 13 with mild polyneuropathy (mDPN) and 25 without polyneuropathy (nDPN)) and 30 healthy controls (HC) were included. Clinical examinations, nerve-conduction-studies and vibratory-perception-thresholds determined the presence and severity of DPN...
April 21, 2017: Diabetes
https://www.readbyqxmd.com/read/28431948/serum-peptides-as-putative-modulators-of-inflammation-in-psoriasis
#6
Tetsuhiko Matsuura, Masaaki Sato, Kouhei Nagai, Toshiyuki Sato, Mitsumi Arito, Kazuki Omoteyama, Naoya Suematsu, Kazuki Okamoto, Tomohiro Kato, Yoshinao Soma, Manae S Kurokawa
BACKGROUND: Psoriasis is a refractory inflammatory disease, however, its pathophysiology is still not fully understood. OBJECTIVE: We tried to identify novel serum peptides associated with the pathophysiology of psoriasis. METHODS: Serum peptides from 24 patients with psoriasis vulgaris (PV), 10 patients with psoriatic arthritis (PsA), 14 patients with atopic dermatitis (AD), and 23 healthy control (HC) subjects were analyzed by mass spectrometry...
March 27, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28431618/muscle-strength-and-power-in-persons-with-multiple-sclerosis-a-systematic-review-and-meta-analysis
#7
REVIEW
Mlk Jørgensen, U Dalgas, I Wens, L G Hvid
BACKGROUND: Multiple sclerosis (MS) is a chronic disease in the central nervous system which causes a number of physical symptoms including impairments of muscle mechanical function (muscle strength, muscle power and explosive muscle strength (~rate of force development, RFD)). However, a full overview of the existing knowledge regarding muscle mechanical function in persons with MS (PwMS) is still pending. OBJECTIVES: To systematically review 1) the psychometric properties of isokinetic dynamometry testing in PwMS, and 2) studies comparing muscle mechanical function in PwMS to matched healthy controls (HC)...
May 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28430272/molecular-rare-earth-metal-alumosilicates
#8
Raúl Huerta-Lavorie, Dana V Báez-Rodríguez, Jessica García-Ríos, Emiliano Martínez-Vollbert, Diego Martínez-Otero, Vojtech Jancik
The synthesis and stabilization of molecular four-coordinated lanthanide alumosilicates was achieved by the use of a highly encumbered alumosilicate ligand LAl(OH·thf)(μ-O)Si(OH)(OtBu)2 (1, L = HC{C(Me)N(2,6-iPr2C6H3)}2). Reactions between 1 and tris-cyclopentadienyl lanthanides (LnCp3; Ln = Ce, Nd, Sm, Gd, Tb, Dy, Y, Er) derived in the isolation of eight compounds (2-9) where the ligand is observed in three different bonding modes: adducts (2, 3), spirocyclic (4) or cyclic (5-9) coordination compounds. The observed reactivity can be related to the ionic radius of the lanthanide atom and the nature of the oxygen donor-atom from the hydroxide (Al-OH) or hydroxyl (Si-OH) moieties in 1...
April 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28429747/imaging-genetics-approach-to-parkinson-s-disease-and-its-correlation-with-clinical-score
#9
Mansu Kim, Jonghoon Kim, Seung-Hak Lee, Hyunjin Park
Parkinson's disease (PD) is a progressive neurodegenerative disorder associated with both underlying genetic factors and neuroimaging findings. Existing neuroimaging studies related to the genome in PD have mostly focused on certain candidate genes. The aim of our study was to construct a linear regression model using both genetic and neuroimaging features to better predict clinical scores compared to conventional approaches. We obtained neuroimaging and DNA genotyping data from a research database. Connectivity analysis was applied to identify neuroimaging features that could differentiate between healthy control (HC) and PD groups...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28429352/difference-in-resting-state-fractional-amplitude-of-low-frequency-fluctuation-between-bipolar-depression-and-unipolar-depression-patients
#10
H-L Yu, W-B Liu, T Wang, P-Y Huang, L-Y Jie, J-Z Sun, C Wang, W Qian, M Xuan, Q-Q Gu, H Liu, F-L Zhang, M-M Zhang
OBJECTIVE: To investigate the difference in fractional amplitude of low-frequency fluctuation (fALFF) of localized brain activities in the resting-state between bipolar depression and unipolar depression patients and to find biological markers that differentiate the two groups of patients. PATIENTS AND METHODS: Thirteen patients with bipolar depression, 15 patients with unipolar depression, and 16 healthy control subjects that were matched in age and years of education were subjected to 3...
April 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28429162/involvement-of-methylated-hbha-expressed-from-mycobacterium-smegmatis-in-an-ifn-%C3%AE-release-assay-to-aid-discrimination-between-latent-infection-and-active-tuberculosis-in-bcg-vaccinated-populations
#11
H-L Wen, C-L Li, G Li, Y-H Lu, H-C Li, T Li, H-M Zhao, K Wu, D B Lowrie, J-X Lv, S-H Lu, X-Y Fan
IFN-γ release assays (IGRAs) based on region of difference 1 (RD1) antigens have improved diagnosis of Mycobacterium tuberculosis (M. tb) infection. However, IGRAs with these antigens cannot discriminate between active tuberculosis (ATB) and latent tuberculosis infection (LTBI). M. tb heparin-binding-hemagglutinin (HBHA) induces relatively high IFN-γ responses in LTBI individuals and low responses in ATB patients, but purification of the native methylated HBHA from cultures of M. tb for immunological tests is complex and time-consuming...
April 20, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28428445/pectinase-treated-panax-ginseng-protects-heat-stress-induced-testicular-damage-in-rats
#12
Min Kyoung Kim, Kyu-Min Cha, Seock-Yeon Hwang, Un-Kyu Park, Seok Kyo Seo, Sang-Ho Lee, Min-Sik Jeong, SiHyun Cho, Spandana Rajendra Kopalli, Si-Kwan Kim
Testicular hyperthermia is well studied to cause impaired spermatogenesis. In the present study, the protective effect of enzymatically modified (pectinase-treated) Panax ginseng (GINST) against intermittent sub-chronic heat stress-induced testicular damage in rats was investigated. Male Sprague-Dawley rats were divided into four groups: normal control (NC), heat-stressed control (HC), heat-stressed plus GINST-100 mg/kg/day (HG100) and heat-stressed plus GINST-200 mg/kg/day (HG200) treatment groups. GINST (100 and 200 mg/kg/day) was mixed separately with a regular pellet diet and was administered orally for 8 weeks starting from 1 week before heat exposure...
June 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28428146/the-correlation-between-mood-states-and-functional-connectivity-within-the-default-mode-network-can-differentiate-internet-gaming-disorder-from-healthy-controls
#13
Guangheng Dong, Hui Li, Lingxiao Wang, Marc N Potenza
The default-mode network (DMN) has been suggested to support a baseline state of brain activity. However, whether connectivity within the DMN is associated with mood states remains incompletely understood. The current study examined the correlation between mood state and the functional connectivity (FC) among DMN regions, and examined if the FC can differentiate Internet gaming disorder (IGD) from healthy controls (HC). Resting state data were collected within 108 college students (IGD,41; HC,67). Negative correlations were observed between measures of: (1) Depression and FCs among ventral DMN regions; (2) Anger and FCs among dorsal DMN regions; and, (3) Anger and Depression and FCs of both the ventral and dorsal DMN...
April 18, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28428068/comparative-analysis-of-gene-expression-profiles-for-several-migrating-cell-types-identifies-cell-migration-regulators
#14
Young-Kyung Bae, Frank Macabenta, Heather Leigh Curtis, Angelike Stathopoulos
Cell migration is an instrumental process that ensures cells are properly positioned to support the specification of distinct tissue types during development. To provide insight, we used fluorescence activated cell sorting (FACS) to isolate two migrating cell types from the Drosophila embryo: caudal visceral mesoderm (CVM) cells, precursors of longitudinal muscles of the gut, and hemocytes (HCs), the Drosophila equivalent of blood cells. ~350 genes were identified from each of the sorted samples using RNA-seq, and in situ hybridization was used to confirm expression within each cell type or, alternatively, within other interacting, co-sorted cell types...
April 17, 2017: Mechanisms of Development
https://www.readbyqxmd.com/read/28427704/comparison-of-brain-and-spinal-cord-magnetic-resonance-imaging-features-in-neuromyelitis-optica-spectrum-disorders-patients-with-or-without-aquaporin-4-antibody
#15
Moli Fan, Ying Fu, Lei Su, Yi Shen, Kristofer Wood, Li Yang, Yaou Liu, Fu-Dong Shi
BACKGROUND: The spinal cord and brain measurements are rarely investigated in neuromyelitis optica (NMO) patients with and without antibodies to aquaporin-4 (AQP4), directly compared to multiple sclerosis (MS) patients. OBJECTIVES: To investigate magnetic resonance imaging (MRI) features of both brain and spinal cord in NMO patients with and without antibodies to AQP4, compared with MS patients and healthy controls (HC). METHODS: We recruited 55 NMO including 30 AQP4 (+) and 25 AQP4 (-), 25 MS and 25 HC...
April 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28427694/gait-pattern-in-patients-with-different-multiple-sclerosis-phenotypes
#16
Irena Dujmovic, Sasa Radovanovic, Vanja Martinovic, Jelena Dackovic, Gorica Maric, Sarlota Mesaros, Tatjana Pekmezovic, Vladimir Kostic, Jelena Drulovic
BACKGROUND: Gait pattern is frequently impaired in multiple sclerosis (MS), however gait characteristics in patients with different MS phenotypes have not been fully elucidated. METHODS: We analyzed spatio-temporal gait pattern characteristics in patients with relapsing-remitting (RR, n=52) and primary-progressive (PP, n=18) MS in comparison with age-matched healthy controls (HC, n=40). All subjects performed a standardized simple walking task, a dual motor- motor task, a dual motor-mental task, and a triple combined motor-mental task at a GAITRite electronic walkway of 5...
April 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28427649/hydrodynamic-cavitation-in-combination-with-the-ozone-hydrogen-peroxide-and-the-uv-based-advanced-oxidation-processes-for-the-removal-of-natural-organic-matter-from-drinking-water
#17
Matej Čehovin, Alojz Medic, Jens Scheideler, Jörg Mielcke, Achim Ried, Boris Kompare, Andreja Žgajnar Gotvajn
Natural organic matter in drinking water is causing concern especially due to the formation of disinfection by-products (DBPs) by chlorine, as these are proven to have adverse health effects on consumers. In this research, humic acid was used as a source of dissolved organic carbon (DOC) in drinking water (up to 3mgL(-1)). The efficiency of DOC removal was studied by applying O3, H2O2/O3, H2O2/UV and O3/UV advanced oxidation processes (AOPs) alone and combined with hybrid hydrodynamic cavitation (HC), generated by an orifice plate, as this technology recently shows promising potential for the treatment of water, containing recalcitrant organic substances...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28427623/degradation-of-reactive-blue-13-using-hydrodynamic-cavitation-effect-of-geometrical-parameters-and-different-oxidizing-additives
#18
Sunil Rajoriya, Swapnil Bargole, Virendra Kumar Saharan
Decolorization of reactive blue 13 (RB13), a sulphonated azo dye, was investigated using hydrodynamic cavitation (HC). The aim of research article is to check the influence of geometrical parameters (total flow area, the ratio of throat perimeter to its cross-sectional area, throat shape and size, etc.) and configuration of the cavitating devices on decolorization of RB13 in aqueous solution. For this purpose, eight cavitating devices i.e. Circular and slit venturi, and six orifice plates having different flow area and perimeter were used in the present work...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28426552/altered-neural-responses-to-heat-pain-in-drug-na%C3%A3-ve-patients-with-parkinson-s-disease
#19
Katarina Forkmann, Wiebke Grashorn, Katharina Schmidt, Odette Fründt, Carsten Buhmann, Ulrike Bingel
Pain is a frequent but still neglected non-motor symptom of Parkinson's disease (PD). However, neural mechanisms underlying pain in PD are poorly understood. Here we explored whether the high prevalence of pain in PD might be related to dysfunctional descending pain control. Using fMRI we explored neural responses during the anticipation and processing of heat pain in 21 PD patients (Hoehn&Yahr I-III) and 23 healthy controls (HC). PD patients were naïve to dopaminergic medication in order to avoid confounding drug effects...
April 18, 2017: Pain
https://www.readbyqxmd.com/read/28425443/hybridization-of-strength-pareto-multiobjective-optimization-with-modified-cuckoo-search-algorithm-for-rectangular-array
#20
Khairul Najmy Abdul Rani, Mohamedfareq Abdulmalek, Hasliza A Rahim, Neoh Siew Chin, Alawiyah Abd Wahab
This research proposes the various versions of modified cuckoo search (MCS) metaheuristic algorithm deploying the strength Pareto evolutionary algorithm (SPEA) multiobjective (MO) optimization technique in rectangular array geometry synthesis. Precisely, the MCS algorithm is proposed by incorporating the Roulette wheel selection operator to choose the initial host nests (individuals) that give better results, adaptive inertia weight to control the positions exploration of the potential best host nests (solutions), and dynamic discovery rate to manage the fraction probability of finding the best host nests in 3-dimensional search space...
April 20, 2017: Scientific Reports
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