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https://www.readbyqxmd.com/read/29451057/comparison-between-modified-dunn-procedure-and-in-situ-fixation-for-severe-stable-slipped-capital-femoral-epiphysis
#1
Giovanni Trisolino, Stefano Stilli, Giovanni Gallone, Pedro Santos Leite, Giovanni Pignatti
Background and purpose - The best treatment option for severe slipped capital femoral epiphysis (SCFE) is still controversial. We compared clinical and radiographic outcomes of modified Dunn procedure (D) and in situ fixation (S) in severe SCFE. Patients and methods - We retrospectively compared D and S, used for severe stable SCFE (posterior sloping angle (PSA) > 50°) in 29 patients (15 D; 14 S). Propensity analysis and inverse probability of treatment weights (IPTW) to adjust for baseline differences were performed...
February 16, 2018: Acta Orthopaedica
https://www.readbyqxmd.com/read/29436472/a-novel-variant-in-glis3-is-associated-with-osteoarthritis
#2
Elisabetta Casalone, Ioanna Tachmazidou, Eleni Zengini, Konstantinos Hatzikotoulas, Sophie Hackinger, Daniel Suveges, Julia Steinberg, Nigel William Rayner, arcOGEN Consortium, Jeremy Mark Wilkinson, Kalliope Panoutsopoulou, Eleftheria Zeggini
OBJECTIVES: Osteoarthritis (OA) is a complex disease, but its genetic aetiology remains poorly characterised. To identify novel susceptibility loci for OA, we carried out a genome-wide association study (GWAS) in individuals from the largest UK-based OA collections to date. METHODS: We carried out a discovery GWAS in 5414 OA individuals with knee and/or hip total joint replacement (TJR) and 9939 population-based controls. We followed-up prioritised variants in OA subjects from the interim release of the UK Biobank resource (up to 12 658 cases and 50 898 controls) and our lead finding in operated OA subjects from the full release of UK Biobank (17 894 cases and 89 470 controls)...
February 7, 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29435896/readmission-rates-and-diagnoses-following-total-hip-replacement-in-relation-to-insurance-payer-status-race-and-ethnicity-and-income-status
#3
Robert S White, Dahniel L Sastow, Licia K Gaber-Baylis, Virginia Tangel, Andrew D Fisher, Zachary A Turnbull
BACKGROUND: Total hip replacements (THRs) are the sixth most common surgical procedure performed in the USA. Readmission rates are estimated at between 4.0 and 10.9%, and mean costs are between $10,000 and $19,000. Readmissions are influenced by the quality of care received. We sought to examine differences in readmissions by insurance payer, race and ethnicity, and income status. METHODS: We analyzed all THRs from 2007 to 2011 in California, Florida, and New York from the State Inpatient Databases, Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality...
February 12, 2018: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29435622/high-bacterial-contamination-rate-of-electrocautery-tips-during-total-hip-and-knee-arthroplasty
#4
Hussein Abdelaziz, Akos Zahar, Christian Lausmann, Thorsten Gehrke, Helmut Fickenscher, Eduardo M Suero, Matthias Gebauer, Mustafa Citak
PURPOSE: The aim of the study was to quantify the bacterial contamination rate of electrocautery tips during primary total joint replacement (TJR), as well as during aseptic and septic revision TJR. METHODS: A total of 150 electrocautery tips were collected between April and July 2017. TJR surgeries were divided into three groups: (1) primary, (2) aseptic and (3) septic revisions. In each group, a total of 50 electrocautery tips were collected. A monopolar electrocautery with a reusable stainless-steel blade tip was used in all cases...
February 12, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29434715/relationship-between-osteoporosis-and-expression-of-bcl-2-and-cxcl12
#5
Tongtao Pang, Mingzhi Gong, Jiangtao Han, Dan Liu
The changes of expression of anti-apoptotic factor B-cell lymphoma 2 (Bcl-2) and chemokine C-X-C motif ligand 12 (CXCL12) in the pathological process of osteoporosis (OP) were investigated, to provide new ideas for the diagnosis and treatment of OP. A total of 60 postmenopausal women who needed to undergo hip replacement surgery were enrolled and divided into osteoporosis group (OP, n=32) and control group (CK, n=28) according to the results of dual-energy X-ray bone density measure; after operation, cancellousbone from the femoral head or femoral neck was removed, and osteoblasts and osteoclasts were isolated and cultured in vitro...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29431491/customizable-pre-printed-consent-forms-a-solution-in-light-of-the-montgomery-ruling
#6
Deborah Owen, Nick Aresti, Alex Mulligan, Dennis Kosuge
INTRODUCTION: This article presents an audit cycle supported quality improvement project addressing best practice in the consent process for lower limb arthroplasty which takes into account the new standard in surgical consent and the importance of material risks. METHODS: 50 consecutive total hip and total knee replacement consent forms over a 3-month period were reviewed for legibility and completeness. Following the introduction of a new, pre-printed but customizable consent form the review process was repeated...
February 2, 2018: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/29430492/a-single-femoral-component-for-all-total-hip-replacements-performed-by-a-trust-does-this-affect-early-clinical-and-radiological-outcomes
#7
James Ricketts, Paul Sherry
Background: Hospitals may be under pressure to implement cost saving strategies regarding prosthesis choice. This may involve the use of components which are not the first preference of individual surgeons, or those they have little experience with. We aim to examine the effect of standardizing the type of femoral stem used in a single trust, and determine whether this is safe practice, particularly in those who have never used this particular stem before. Methods: We report results at 2 years of 151 primary total hip arthroplasties performed using a single femoral stem...
January 2018: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29429942/pooled-human-serum-a-new-culture-supplement-for-bioreactor-based-cell-therapies-preliminary-results
#8
Sara Savelli, Luisa Trombi, Delfo D'Alessandro, Stefania Moscato, Simone Pacini, Simone Lapi, Fabrizio Scatena, Stefano Giannotti, Mario Petrini
BACKGROUND AIMS: Bone marrow mesenchymal stromal cells (MSCs) are an appealing source for several cell-based therapies. Many bioreactors, such as the Quantum Cell Expansion System, have been developed to generate a large number of MSCs under Good Manufacturing Practice conditions by using human platelet lysate (HPL). Previously, we isolated a novel cell population in human bone marrow, mesodermal progenitor cells (MPCs), which we identified as precursors of MSCs. MPCs may represent an important cell source for regenerative medicine applications...
February 8, 2018: Cytotherapy
https://www.readbyqxmd.com/read/29428222/cost-utility-analysis-in-orthopaedic-trauma-what-pays-a-systematic-review
#9
S Coyle, S Kinsella, B Lenehan, J M Queally
BACKGROUND: As healthcare systems come under ever-increasing pressure to provide more care with fewer resources, emphasis is being placed on value-based systems that maximise quality and minimize cost. The aim of this study was to determine which interventions in fracture care have been demonstrated to be cost effective. METHODS: A systemic review of cost-utility studies on the management of fractures from 1976 to 2015 was carried out using a search of the Cost-Effectiveness Analysis Registry, National Health Service Economic Evaluation Database (NHS EED) and MEDLINE...
January 31, 2018: Injury
https://www.readbyqxmd.com/read/29426007/how-do-patients-trade-off-surgeon-choice-and-waiting-times-for-total-joint-replacement-a-discrete-choice-experiment
#10
Deborah A Marshall, Ken Deal, Barbara Conner-Spady, Eric Bohm, Gillian Hawker, Lynda Loucks, Karen V MacDonald, Tom Noseworthy
OBJECTIVE: Patients face significant waiting times for hip and knee total joint replacement (TJR) in publicly funded healthcare systems. We aimed to assess how surgeon selection and reputation affect patients' willingness to wait for TJR. DESIGN: We assessed patient preferences using a discrete choice experiment questionnaire with 12 choice scenarios administered to patients referred for TJR. Based on qualitative research, pre- and pilot-testing, we characterized each scenario by five attributes: surgeon reputation, surgeon selection, waiting time to surgeon visit (initial consultation), waiting time to surgery, and travel time to hospital...
February 6, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29423757/comparing-the-validity-and-responsiveness-of-the-eq-5d-5l-to-the-oxford-hip-and-knee-scores-and-sf-12-in-osteoarthritis-patients-1-year-following-total-joint-replacement
#11
Barbara L Conner-Spady, Deborah A Marshall, Eric Bohm, Michael J Dunbar, Tom W Noseworthy
PURPOSE: (1) To assess responsiveness of the EQ-5D-5L compared to Oxford hip and knee scores and the SF-12 in osteoarthritis patients undergoing total hip (THR) or knee (TKR) replacement surgery; (2) to compare distribution and anchor-based methods of assessing responsiveness. METHODS: Questionnaires were mailed to consecutive patients following surgeon referral for primary THR or TKR and 1 year post-surgery. We assessed effect size (ES), standardized response mean (SRM), and standard error of measurement (SEM)...
February 8, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29422350/the-ideal-total-hip-replacement-bearing-surface-in-the-young-patient-%C3%A2-a-prospective-randomized-trial-comparing-alumina-ceramic-on-ceramic-with-ceramic-on-conventional-polyethylene-15-year-follow-up
#12
Amit Atrey, Jesse I Wolfstadt, Nasir Hussain, Amir Khoshbin, Sarah Ward, Emil H Schemitsch, James P Waddell
BACKGROUND: The optimum bearing surface for total hip arthroplasty remains debatable. We have previously published our outcome at 10 years and this represents the 15-year follow-up. METHODS: A total of 58 hips (in 57 patients with a mean age of 42 years) were randomized to receive either ceramic-on-ceramic (CoC) or ceramic-on-polyethylene (CoP) total hip arthroplasty. We prospectively followed for survivorship, functional outcomes (using the Harris Hip Score and the St Michael's Hip Score [SMH]), and radiological outcomes...
December 6, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29419468/disparities-in-outcomes-for-blacks-versus-whites-undergoing-total-hip-arthroplasty-a-systematic-literature-review
#13
Bella Y Mehta, Anne R Bass, Rie Goto, Linda A Russell, Michael L Parks, Mark P Figgie, Susan M Goodman
OBJECTIVE: Total hip replacement (THA) surgery is a successful procedure, yet blacks in the United States undergo THA less often and reflect poorer outcomes than whites. The purpose of this study is to systematically review the literature on health-related quality of life after THA, comparing blacks and whites. METHODS: A librarian-assisted search was performed in Medline through PubMed, Embase, and Cochrane Library on February 27, 2017. Original cohort studies examining pain, function, and satisfaction in blacks and whites 1 year after elective THA were included...
February 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29417775/-mechanical-complications-with-self-made-antibiotic-loaded-cement-articulating-spacers-in-the-treatment-of-the-infected-hip-replacement
#14
Yin-Qiao Du, Yong-Gang Zhou, Li-Bo Hao, Wen-Ming Wu, Hai-Yang Ma, Chong Zheng, Shang Piao, Zhi-Sen Gao, Jing-Yang Sun, Sen Wang
OBJECTIVE: To study the complications and efficacy of self-made, antibiotic-loaded cement articulating spacers in the treatment of the infected hip replacement. METHODS: Between January 2006 and July 2016, 265 patients (266 hips) received a self-made, antibiotic-loaded cement articulating spacer as part of a two-stage protocol. Among those patients, there were 143 males(144 hips) and 122 females(122 hips). The cement articulating spacers with vancomycin and two Steinman pins were made by a self-made mold system...
May 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29416861/prevalence-and-management-of-intrathecal-morphine-induced-pruritus-in-new-zealand-m%C3%A4-ori-healthcare-recipients
#15
Jennifer M Woods, Anecita Gigi Lim
Aims and objectives: The aim of this article was to determine whether the incidence of intrathecal morphine-induced pruritus (ITMI) was influenced by ethnicity, age or gender in relation to orthopaedic versus caesarean surgeries. Background: The use of intrathecal morphine for patients undergoing total hip and knee joint replacements and for lower segment caesarean sections (LSCS) has gained popularity worldwide since its introduction over 30 years ago. Several international studies show that morphine delivered via the intrathecal route is an effective and safe method of pain relief...
February 2018: British Journal of Pain
https://www.readbyqxmd.com/read/29416151/pre-procedure-ultrasound-guided-paramedian-spinal-anaesthesia-at-l5-s1-is-this-better-than-landmark-guided-midline-approach-a-randomised-controlled-trial
#16
Karthikeyan Kallidaikurichi Srinivasan, Anne-Marie Leo, Gabriella Iohom, Frank Loughnane, Peter J Lee
Background and Aims: Routine use of pre-procedural ultrasound guided midline approach has not shown to improve success rate in administering subarachnoid block. The study hypothesis was that the routine use of pre-procedural (not real time) ultrasound-guided paramedian spinals at L5-S1 interspace could reduce the number of passes (i.e., withdrawal and redirection of spinal needle without exiting the skin) required to enter the subarachnoid space when compared to the conventional landmark-guided midline approach...
January 2018: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29411077/regenerative-therapies-increase-survivorship-of-avascular-necrosis-of-the%C3%A2-femoral-head-a-systematic-review-and-meta-analysis
#17
REVIEW
Luca Andriolo, Giulia Merli, Carlos Tobar, Sante Alessandro Altamura, Elizaveta Kon, Giuseppe Filardo
PURPOSE: The aim of this study was to document the available evidence on the use of regenerative techniques for the treatment of femoral head osteonecrosis (or avascular necrosis of femoral head, AVN) and to understand their benefit compared to core decompression (CD) alone in avoiding failure and the need for total hip replacement (THR). METHODS: The search was conducted on three medical electronic databases according to PRISMA guidelines. The studies reporting number and timing of failures were included in a meta-analysis calculating cumulative survivorship with a Kaplan-Mayer curve...
February 6, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29407518/hospital-readmissions-among-total-hip-replacement-patients-in-2009-and-2014
#18
Michael P Cary, Victoria Goode, Nancy Crego, Deirdre Thornlow, Cathleen Colón-Emeric, Helen M Hoenig, Kayla Baba, Scarlet Fellingham, Elizabeth I Merwin
OBJECTIVE: To document changes in 30-day hospital readmission rates and causes for returning to the hospital for care among THR patients in US hospitals in 2009 and 2014. DESIGN: Cross-sectional, retrospective descriptive. We used data from the Nationwide Readmissions Database (NRD) which is drawn from the Healthcare Cost and Utilization Project (HCUP) net - sponsored by the Agency for Healthcare Research and Quality (AHRQ). SETTING: The AHRQ database, known as NRD, is based on a 20% sample of all hospital discharges in the nation...
January 30, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29406339/implications-of-introducing-new-technology-comparative-survivorship-modeling-of-metal-on-metal-hip-replacements-and-contemporary-alternatives-in-the-national-joint-registry
#19
Linda P Hunt, Michael R Whitehouse, Andrew Beswick, Martyn L Porter, Peter Howard, Ashley W Blom
BACKGROUND: New medical technologies are often used widely without adequate supporting data, a practice that can lead to widespread catastrophic failure such as occurred with metal-on-metal (MoM) hip replacements. We determined both how revision rates would have differed if, instead of receiving MoM hip replacements, patients had received existing alternatives and the subsequent cumulative re-revision rates of the patients who did receive MoM hip replacements compared with alternatives...
February 7, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29402716/gait-analysis-of-leg-length-discrepancy-differentiated-hip-replacement-patients-with-developmental-dysplasia-a-midterm%C3%A2-follow-up
#20
Guo Chen, Yong Nie, Jinwei Xie, Guorui Cao, Qiang Huang, Fuxing Pei
BACKGROUND: Few studies investigate gait characteristics and symmetry of developmental dysplasia of the hip patients (Crowe II and III) after total hip arthroplasty (THA) whose leg length discrepancy (LLD) is within 20 mm. Our study aimed to explore whether gait analysis parameters in these patients can return to the level of unaffected people and how bodies compensate for the discrepancy. METHOD: A total of 45 patients who underwent cementless THA and 20 healthy controls were involved in this study prospectively...
December 21, 2017: Journal of Arthroplasty
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