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Symptom validity testing

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https://www.readbyqxmd.com/read/29152814/depression-young-age-chronic-marijuana-use-and-interepisodic-symptoms-predict-psychological-distress-in-patients-with-cyclic-vomiting-syndrome
#1
Tatyana Taranukha, Vishnu Charan Suresh Kumar, Alex Seamon, Natasha Sahr, Aniko Szabo, Thangam Venkatesan
BACKGROUND: Cyclic vomiting syndrome (CVS) is often triggered by stress. Patients report high degrees of psychological distress due to CVS, but there is limited data on factors associated with psychological distress. We sought to determine the degree of psychological distress and its correlation with clinical characteristics in CVS. METHODS: The Brief Symptom Inventory (BSI), a validated tool to determine psychological distress, was administered prospectively to patients...
November 20, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29152767/development-and-validation-of-a-primary-sclerosing-cholangitis-specific-patient-reported-outcomes-instrument-the-psc-pro
#2
Zobair M Younossi, Arian Afendy, Maria Stepanova, Andrei Racila, Fatema Nader, Rachel Gomel, Ricky Safer, William R Lenderking, Anne Skalicky, Leah Kleinman, Robert P Myers, G Mani Subramanian, John G McHutchison, Cynthia Levy, Christopher L Bowlus, Kris Kowdley, Andrew J Muir
BACKGROUND: PSC is a chronic liver disease associated with inflammation and biliary fibrosis that leads to cholangitis, cirrhosis, and impaired quality of life. Our objective was to develop and validate a PSC-specific PRO instrument. METHODS: We developed a 42-item PSC PRO instrument that contains 2 modules (Symptoms and Impact of Symptoms), and conducted external validation. Reliability and validity were evaluated using clinical data and a battery of other validated instruments...
November 20, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29152735/6%C3%A2-hz-corneal-kindling-in-mice-triggers-neurobehavioral-comorbidities-accompanied-by-relevant-changes-in-c-fos-immunoreactivity-throughout-the-brain
#3
Giulia Albertini, Laura Walrave, Thomas Demuyser, Ann Massie, Dimitri De Bundel, Ilse Smolders
OBJECTIVE: Besides seizures, patients with epilepsy are affected by a variety of cognitive and psychiatric comorbidities that further impair their quality of life. The present study provides an in-depth characterization of the behavioral alterations induced by 6 Hz corneal kindling. Furthermore, we correlate these behavioral changes to alterations in c-Fos protein expression throughout the brain following kindling. METHODS: Adolescent male Naval Medical Research Institute (NMRI) mice were kindled via repetitive subconvulsive 6 Hz corneal stimulations until they reached the fully kindled state (defined as 10 consecutive generalized seizures)...
November 20, 2017: Epilepsia
https://www.readbyqxmd.com/read/29151848/developing-and-validating-of-ramathibodi-appendicitis-score-rama-as-for-diagnosis-of-appendicitis-in-suspected-appendicitis-patients
#4
Chumpon Wilasrusmee, Boonying Siribumrungwong, Samart Phuwapraisirisan, Napaphat Poprom, Patarawan Woratanarat, Panuwat Lertsithichai, John Attia, Ammarin Thakkinstian
Background: Diagnosis of appendicitis is still clinically challenging where resources are limited. The purpose of this study was to develop and externally validate Ramathibodi Appendicitis Score (RAMA-AS) in aiding diagnosis of appendicitis. Methods: A two-phase cross-sectional study (i.e., derivation and validation) was conducted at Ramathibodi Hospital (for derivation) and at Thammasat University Hospital and Chaiyaphum Hospital (for validation). Patients with abdominal pain and suspected of having appendicitis were enrolled...
2017: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/29150985/general-illness-and-psychological-factors-in-patients-with-chronic-nasal-symptoms
#5
Naveed Kara, Alexander C Yao, Julia Newton, Vincent Deary, James O'Hara, Janet A Wilson
OBJECTIVES: Only a minority of patients referred to specialists with sinonasal symptoms have clear evidence of chronic rhinosinusitis. This study aims to estimate the prevalence of and associations between (i) general illness factors (fatigue, autonomic dysfunction) and (ii) psychological factors (anxiety, depression, somatisation, personality traits) in patients presenting with sinonasal symptoms. DESIGN: The following validated questionnaires were administered to patients: the Sino-Nasal Outcome Test-22 (SNOT-22) to identify symptom burden, Composite Autonomic Symptom Score-31 (COMPASS-31) measuring autonomic function, Chalder fatigue questionnaire, Patient Health Questionnaire-15 (PHQ-15) addressing somatisation symptoms, Hospital Anxiety and Depression Scale (HADS), and the International Personality Item Pool-50 (IPIP-50)...
November 18, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29150898/a-model-to-characterize-psychopathological-features-in-adults-with-prader-willi-syndrome
#6
Denise Thuilleaux, Virginie Laurier, Pierre Copet, Julie Tricot, Geneviève Demeer, Fabien Mourre, Maithé Tauber, Joseba Jauregi
High prevalence of behavioral and psychiatric disorders in adults with Prader-Willi Syndrome (PWS) has been reported in last few years. However, data are confusing and often contradictory. In this article, we propose a model to achieve a better understanding of the psychopathological features in adults with PWS. The study is based on clinical observations of 150 adult inpatients, males and females. Non-parametric statistics were performed to analyse the association of psychopathological profiles with genotype, gender and age...
November 17, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29145910/brain-activation-during-emotion-regulation-in-women-with-premenstrual-dysphoric-disorder
#7
Nicole Petersen, Dara G Ghahremani, Andrea J Rapkin, Steven M Berman, Letty Liang, Edythe D London
BACKGROUND: Difficulties in regulating emotions are linked to the core symptoms of premenstrual dysphoric disorder (PMDD). We therefore investigated the neural substrates of emotion-regulation problems in women with PMDD. METHODS: On the basis of self-evaluations over 2 months on the Daily Record of Severity of Problems, eligible participants were assigned to two groups: PMDD and control (18 per group). Functional magnetic resonance imaging (fMRI) and a well-validated task were used to assess brain function during emotion regulation...
November 17, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29144607/eustachian-tube-dysfunction-symptoms-in-patients-treated-in-a-tertiary-rhinology-clinic
#8
Michael J Marino, Lina Chooi Ling, William C Yao, Amber Luong, Martin J Citardi
BACKGROUND: Ear symptoms are common among patients presenting to a rhinology clinic. Validated inventories are available for patient quality-of-life in sinonasal disease and Eustachian tube dysfunction (ETD). This study sought to determine the extent of ETD symptoms, using validated metrics, in a large population of patients presenting to a tertiary rhinology clinic. METHODS: Seven-item Eustachian Tube Dysfunction Questionnaires (ETDQ-7) and 22-item Sino-Nasal Outcome Tests (SNOT-22) were prospectively collected from 492 patients treated in a tertiary rhinology clinic...
November 16, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29133114/neurocognitive-performance-profile-postparathyroidectomy-a-pilot-study-of-computerized-assessment
#9
Caitlin F Bell, Mathew M Warrick, Kathleen C Gallagher, Naira Baregamian
BACKGROUND: Neurocognitive symptoms attributable to primary hyperparathyroidism are important diagnostic criteria, yet the basic characterization and assessment of neurocognitive deficits in primary hyperparathyroidism are not defined fully. METHODS: In this prospective pilot study, patients with unequivocal biochemical diagnosis of primary hyperparathyroidism were evaluated for neurocognitive performance preoperatively and postparathyroidectomy (2 weeks, 6 months) using a battery of computerized modular tests designed by LUMOSITY...
November 10, 2017: Surgery
https://www.readbyqxmd.com/read/29132642/validity-of-arabic-version-of-the-two-question-quick-inventory-of-depression-qid-2-ar-screening-for-multiple-sclerosis-in-an-arab-environment-and-during-the-syrian-war
#10
A Kubitary, M A Alsaleh
PURPOSE: This study aimed to validate the Arabic version of the two-question Quick Inventory of Depression (QID-2-Ar) in multiple sclerosis (MS) patients living in Syria during the war. METHODS: A total of 100 Syrian MS patients, aged 18-60 years, were recruited at Damascus Hospital and Ibn Al-Nafees Hospital to validate the QID-2-Ar, including analyses of its screening test parameters and its construct validity. RESULTS: The QID-2-Ar screening parameters for depression tested very positively, and its construct validity was also favorable (P<0...
November 10, 2017: Revue Neurologique
https://www.readbyqxmd.com/read/29131364/quality-of-life-is-significantly-impaired-in-non-allergic-rhinitis-patients
#11
Christine L Segboer, Ingrid Terreehorst, Artur Gevorgyan, Peter W Hellings, Cornelis M van Drunen, Wytske J Fokkens
BACKGROUND: In contrast to the well-known significant impairment of quality of life (QoL) in allergic rhinitis (AR), the degree of impairment in QoL in non-allergic rhinitis (NAR) remained unknown for a long time, due to a lack of a validated questionnaire to assess QoL in the NAR patient group. In this study a validation for the mini-RQLQ questionnaire in NAR patients was performed, followed by an assessment of QoL in NAR patients compared to AR and healthy controls. Secondly, use of medication and treatment satisfaction in AR and NAR was assessed...
November 13, 2017: Allergy
https://www.readbyqxmd.com/read/29129348/performance-of-the-tinnitus-functional-index-as-a-diagnostic-instrument-in-a-uk-clinical-population
#12
Kathryn Fackrell, Deborah A Hall, Johanna G Barry, Derek J Hoare
OBJECTIVES: The Tinnitus Functional Index (TFI) has been optimised as a diagnostic tool for quantifying the functional impact of tinnitus in US veteran and civilian groups. However, the TFI has not been fully evaluated for use in other English-speaking clinical populations despite its increasingly popular uptake. Here, a prospective multi-site longitudinal validation study was conducted to evaluate psychometric properties relevant to the UK clinical population. Guided by quality criteria for the measurement properties of health-related questionnaires, we specifically evaluated three diagnostic properties relating to the degree to which the TFI (i) covers the eight dimensions proposed to be important for diagnosis, (ii) reliably distinguishes individual differences in severity of tinnitus, and (iii) reliably measures the functional impact of tinnitus...
November 9, 2017: Hearing Research
https://www.readbyqxmd.com/read/29128434/the-korean-version-of-the-voice-symptom-scale-for-patients-with-thyroid-operation-and-its-use-in-a-validation-and-reliability-study
#13
Hee Young Son, Chang-Yoon Lee, Kyung A Kim, Sina Kim, Hee Seok Jeong, Jin Pyeong Kim
OBJECTIVES: The Voice Symptom Scale (VoiSS) questionnaire is a self-reported measure of voice function. Compared with previous voice-rating tools, the VoiSS focuses more on communication difficulties, pharyngeal symptoms, and psychosocial distress. This study aimed to translate the VoiSS into the Korean language, validate it, and assess its reliability. STUDY DESIGN: This is a prospective patient study utilizing questionnaires and acoustic analysis. METHODS: A recognized methodology was used to translate the questionnaires...
November 8, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29128337/the-urticaria-activity-score-validity-reliability-and-responsiveness
#14
Tomasz Hawro, Tatevik Ohanyan, Nicole Schoepke, Martin Metz, Adriane Peveling-Oberhag, Petra Staubach, Marcus Maurer, Karsten Weller
BACKGROUND: Chronic spontaneous urticaria is characterized by fluctuating symptoms. Its activity is assessed with the urticaria activity score (UAS). Two versions of the urticaria activity score used for 7 consecutive days (UAS7) are available: (1) The guideline-recommended UAS7, with once-daily documentation, and (2) the UAS7TD, with twice-daily documentation. OBJECTIVE: To better characterize both UAS7 versions with regard to their validity, reliability, sensitivity to change, minimal important difference (MID), and smallest detectable change (SDC)...
November 8, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29126309/a-cpanet-consensus-statement-on-research-priorities-for-chronic-pulmonary-aspergillosis-a-neglected-fungal-infection-that-requires-attention
#15
Cendrine Godet, Ana Alastruey-Izquierdo, Holger Flick, Christophe Hennequin, Rihards Mikilps-Mikgelbs, Oxana Munteanu, Iain Page, Danila Seidel, Helmut J F Salzer
Chronic pulmonary aspergillosis (CPA) is a severe fungal infection with a high morbidity and mortality, and is usually seen in immunocompetent patients with respiratory disorders. Clinical presentation is nonspecific and often overlaps with the symptoms and the radiological pattern caused by the underlying disease. Clinical management of CPA is further hampered by limited information about the epidemiology, disease dynamics, sensitivity and specificity of different mycological tests, mechanisms of antifungal resistance, efficient treatment and management strategies...
November 6, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29125413/a-computational-fluid-dynamics-simulation-framework-for-ventricular-catheter-design-optimization
#16
Sofy H Weisenberg, Stephanie C TerMaath, Charlotte N Barbier, Judith C Hill, James A Killeffer
OBJECTIVE Cerebrospinal fluid (CSF) shunts are the primary treatment for patients suffering from hydrocephalus. While proven effective in symptom relief, these shunt systems are plagued by high failure rates and often require repeated revision surgeries to replace malfunctioning components. One of the leading causes of CSF shunt failure is obstruction of the ventricular catheter by aggregations of cells, proteins, blood clots, or fronds of choroid plexus that occlude the catheter's small inlet holes or even the full internal catheter lumen...
November 10, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29123479/knowledge-on-alzheimer-s-disease-among-public-hospitals-and-health-clinics-pharmacists-in-the-state-of-selangor-malaysia
#17
Thimarul Huda Mat Nuri, Yet Hoi Hong, Long Chiau Ming, Suhaidah Mohd Joffry, Muhamad Faiz Othman, Chin Fen Neoh
The prevalence of Alzheimer's disease (AD) has increased with the fast growing of aging population, thereby posing great challenges to provision of care for AD patients. Pharmacists play a vital role in the management of AD; this includes recognizing early symptoms of AD, providing medication counseling to AD patients and their caretakers, and identifying potential adverse drug reactions. A comprehensive understanding of the disease progression, as well as the pharmacological therapy, is essential to provide effective care to AD patients...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29123349/the-psychometric-properties-and-factor-structure-of-persian-version-of-edmonton-symptom-assessment-scale-in-cancer-patients
#18
Younes Khalili-Parapary, Mehdi Heidarzadeh, Naser Mozaffari, Parisa Naseri
Context: Edmonton Symptom Assessment Scale (ESAS) was developed to assess objective and subjective symptoms in patients with cancer in all stages of their disease. Aim: The aim of the study was to translate and determine the psychometric properties of ESAS in an Iranian population. Materials and Methods: The current study was carried out to determine reliability and validity of ESAS using 246 patients with cancer in Imam Khomeini Hospital, Ardabil, Iran...
October 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29122806/diagnostic-utility-of-appetite-loss-in-addition-to-existing-prediction-models-for-community-acquired-pneumonia-in-the-elderly-a-prospective-diagnostic-study-in-acute-care-hospitals-in-japan
#19
Toshihiko Takada, Yosuke Yamamoto, Kazuhiko Terada, Mitsuyasu Ohta, Wakako Mikami, Hajime Yokota, Michio Hayashi, Jun Miyashita, Teruhisa Azuma, Shingo Fukuma, Shunichi Fukuhara
OBJECTIVE: Diagnosis of community-acquired pneumonia (CAP) in the elderly is often delayed because of atypical presentation and non-specific symptoms, such as appetite loss, falls and disturbance in consciousness. The aim of this study was to investigate the external validity of existing prediction models and the added value of the non-specific symptoms for the diagnosis of CAP in elderly patients. DESIGN: Prospective cohort study. SETTING: General medicine departments of three teaching hospitals in Japan...
November 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/29122720/connectome-based-predictive-modeling-of-attention-comparing-different-functional-connectivity-features-and-prediction-methods-across-datasets
#20
Kwangsun Yoo, Monica D Rosenberg, Wei-Ting Hsu, Sheng Zhang, Chiang-Shan R Li, Dustin Scheinost, R Todd Constable, Marvin M Chun
Connectome-based predictive modeling (CPM; Finn et al., 2015; Shen et al., 2017) was recently developed to predict individual differences in traits and behaviors, including fluid intelligence (Finn et al., 2015) and sustained attention (Rosenberg et al., 2016a), from functional brain connectivity (FC) measured with fMRI. Here, using the CPM framework, we compared the predictive power of three different measures of FC (Pearson's correlation, accordance, and discordance) and two different prediction algorithms (linear and partial least square [PLS] regression) for attention function...
November 6, 2017: NeuroImage
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