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Diabetic coma

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https://www.readbyqxmd.com/read/27917212/stroke-in-patients-with-diabetes-mellitus-a-study-from-north-western-nigeria
#1
Lukman Owolabi, Mansur Nagode, Aliyu Ibrahim, Andrew Uloko, Ibrahim Gezawa, Mohammad Datti
BACKGROUND: Stroke is one of the major causes of morbidity and mortality worldwide and apart from being exceedingly harmful in diabetics, stroke is a disabling disorder. The study was undertaken to describe the clinical characteristics, outcome pattern and predictors of mortality in a cohort of diabetic patients presenting with stroke in two tertiary health facilities in North Western Nigeria. METHOD: Out of all stroke patients seen from June 2007 to February 2011, persons with diabetes mellitus presenting with stroke in the emergency unit of the two tertiary hospitals in Kano were consecutively recruited for the study...
September 2016: African Health Sciences
https://www.readbyqxmd.com/read/27896327/a-case-of-mediastinitis-accompanied-with-hyperosmolar-nonketotic-coma
#2
Mazhar Muslum Tuna, Faruk Kilinc, Zafer Pekkolay, Hikmet Soylu, Alpaslan Kemal Tuzcu
Mediastinitis is a serious infection involving mediastinal spaces after cervical infections spread along the facial planes. A late diagnosis of mediastinitis may result in death. Here we present a diabetic patient suffered from mediastinit accompanied with hyperosmolar nonketotic coma. A 61 years old male patient with type 2 diabetes was admitted to our hospital, with complaint of generalized worsening and fever. A diagnosis of nonketotic hyperosmolar coma was done and proper treatment started immediately. Neck tomography revealed abscess formation in the upper mediastinum...
June 2016: Turkish Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27873051/clinical-and-radiological-course-of-intracerebral-haemorrhage-associated-with-the-new-non-vitamin-k-anticoagulants
#3
Christian von der Brelie, Alexandros Doukas, Rebecca Naumann, Astrid Dempfle, Naomi Larsen, Michael Synowitz, Olav Jansen, Maximilian Mehdorn, Senol Jadik
BACKGROUND: Clinical outcome and mortality in intracerebral haemorrhage (ICH) associated with anticoagulant treatment is poor. Novel direct oral anticoagulant drugs (NOACs) are increasingly prescribed. Management of NOAC-associated ICH might be more challenging. The aim of this study was to compare the clinical and radiological course of ICH patients being treated with different forms of oral anticoagulant drugs. METHOD: The study is a retrospective observational study...
November 21, 2016: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27843452/challenges-in-modelling-hypoglycaemia-associated-autonomic-failure-a-review-of-human-and-animal-studies
#4
REVIEW
Manjula Senthilkumaran, Xin-Fu Zhou, Larisa Bobrovskaya
Recurrent insulin-induced hypoglycaemia is a major limitation to insulin treatment in diabetes patients leading to a condition called hypoglycaemia-associated autonomic failure (HAAF). HAAF is characterised by reduced sympathoadrenal response to subsequent hypoglycaemia thereby predisposing the patients to severe hypoglycaemia that can lead to coma or even death. Despite several attempts being made, the mechanism of HAAF is yet to be clearly established. In order for the mechanism of HAAF to be elucidated, establishing a human/animal model of the phenomenon is the foremost requirement...
2016: International Journal of Endocrinology
https://www.readbyqxmd.com/read/27832021/adiponectin-leptin-and-inflammatory-markers-in-hiv-associated-metabolic-syndrome-in-children-and-adolescents
#5
María Espiau, Diego Yeste, Antoni Noguera-Julian, Pere Soler-Palacín, Clàudi Fortunyc, Roser Ferrer, Immaculada Comas, Andrea Martín-Nalda, Ángela Deyà-Martínez, Concepció Figueras, Antonio Carrascosa
BACKGROUND: Metabolic syndrome (MetS) is more common in HIV-infected adults and children than in the general population. Adipocytokines and inflammatory markers may contribute to the pathophysiology of this condition and could be useful indices for monitoring MetS. The objective of this study was to provide information on the prevalence of MetS and investigate the role of adipocytokines and other biomarkers in this syndrome in HIV-infected pediatric patients. METHODS: A cross-sectional study was conducted between October 2013 and March 2014 in the outpatient clinics of two tertiary pediatric referral hospitals...
November 8, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27821396/morphine-induced-hearing-loss
#6
Leire Leache, Irene Aquerreta, Libe Moraza, Ana Ortega
PURPOSE: A case of severe bilateral sensorineural hearing loss associated with oral morphine is reported. SUMMARY: A 52-year-old Spanish man was admitted to the intensive care unit with a Glasgow Coma Scale score of 3, a fever, and sudden hearing loss with tinnitus in both ears. His medical history included type 2 diabetes mellitus, depression, sleep disorder, and hypertension. The patient also had pyelonephritis in 2011 and pulmonary embolism in 2014, requiring the placement of an inferior vena cava filter and chronic anticoagulation...
November 15, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27793876/pseudohyperglycaemia-in-a-comatose-patient-after-picking-cherries
#7
Clément Derkenne, Antoine Lamblin, Daniel Jost, Jean-Pierre Tourtier
We report a case of pseudohyperglycaemia on a capillary blood glucose measurement taken from fingers stained with sugar (fructose). A 76-year-old patient with type 1 diabetes received emergency attention at home because of a coma. The first capillary blood glucose measurement collected from a finger revealed a concentration higher than the reference limits, misleading the clinician. After starting symptomatic treatment, a second blood glucose measurement was taken. This measurement, taken at the earlobe, revealed profound hypoglycaemia (0...
October 28, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27747715/coma-after-quetiapine-fumarate-intentional-overdose-in-a-71-year-old-man-a-case-report
#8
S Gibiino, A Trappoli, B Balzarro, A R Atti, D De Ronchi
A 71-year-old man developed coma with severe respiratory failure, hypotension, and tachycardia induced by the intentional ingestion of quetiapine fumarate extended release (XR) 20 g. At the time, he had been treated for bipolar depression with venlafaxine 75 mg/day, lamotrigine 100 mg/day, pregabalin 75 mg/day, and quetiapine XR 400 mg/day for approximately 1 year. Comorbidities were hypertension treated with metoprolol, diabetes mellitus type 2 treated with metformin, and benign prostatic hyperplasia treated with silodosin...
December 2015: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/27701696/-severe-hypoglycemia-following-tramadol-intake-in-a-79-year-old-non-diabetic-patient
#9
Cornelius Kürten, Mladen Tzvetkov, Volker Ellenrieder, Harald Schwörer
History and clinical findings | We report about a 79 year old non-diabetic patient who was admitted to the emergency room with severe hypoglycemia (blood glucose level: 36 mg / dl and Glasgow Coma Scale Score: 3). After the infusion of G40 % her blood glucose level stabilised. The patient reported to have taken 50 mg of Tramadol during the night to treat her headache. Investigations and diagnosis | No other differential diagnosis for hypoglycemia (i.e. diabetes, insulinoma, severe liver or kidney disease) could be established...
September 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27695379/hyperglycemia-a-predictor-of-death-in-severe-head-injury-patients
#10
Simin Babaie Kafaki, Kamaledin Alaedini, Ashkan Qorbani, Leila Asadian, Kaveh Haddadi
OBJECTIVES: Management of hyperglycemia during an acute sickness in adults is accompanied by improved outcomes. We have designed a prospective study with meticulous attention to exclude all diabetes patients by checking hemoglobin A1c (HbA1c or glycated hemoglobin) to avoid the ill-effects of hyperglycemia in patients with traumatic head injury admitted to the intensive care unit (ICU). METHODS: This prospective study included adults with traumatic primary brain injury with a Glasgow coma score of ≤8 necessitating mechanical ventilation treated in the period 2012-2015...
2016: Clinical Medicine Insights. Endocrinology and Diabetes
https://www.readbyqxmd.com/read/27652078/effectiveness-of-computerized-point-of-care-reminders-on-adherence-with-multiple-clinical-recommendations-by-primary-health-care-providers-protocol-for-a-cluster-randomized-controlled-trial
#11
Leonardo Méndez Boo, Ermengol Coma, Manuel Medina, Eduardo Hermosilla, Manuel Iglesias, Carmen Olmos, Sebastian Calero Muñoz, Johanna Caro Mendivelso
BACKGROUND: To determine the effectiveness of reminders compared to no reminders in improving adherence to multiple clinical recommendations measured as the resolution of the clinical condition that motivated the reminder, in a primary care setting with a well-established feedback system. METHODS/DESIGN: A 12-month, cluster-randomized, controlled clinical trial was designed (randomized by primary care team) to evaluate the impact of computerized reminders. All study participants will continue to receive the usual feedback from the electronic health records system...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27646495/prospective-study-of-hypothalamo-hypophyseal-dysfunction-in-children-and-adolescents-following-traumatic-brain-injury
#12
David Krahulik, Darina Aleksijevic, Vratislav Smolka, Eva Klaskova, Petra Venhacova, Miroslav Vaverka, Vladimir Mihal, Jirina Zapletalova
BACKGROUND AND AIMS: Retrospective studies of TBI have found a neuroendocrine dysfunction following traumatic brain injury in 23 to 60% of adults and 15 to 21% of children. Our aims were to determine the prevalence of hypothalamo-hypophyseal dysfunction in children following brain injury, assess its relationship to the type of injury and the course of the acute post-traumatic phase. PATIENTS AND METHODS: Body development (growth, pubertal development, and skeletal maturity) were evaluated in 58 patients (21 girls) after a brain injury rated 3 to 12 on the Glasgow Coma Scale (GCS)...
September 19, 2016: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/27614907/-my-heart-burns-a-qualitative-study-of-perceptions-and-experiences-of-type-1-diabetes-among-children-and-youths-in-tajikistan
#13
Severina Haugvik, David Beran, Pamela Klassen, Akhtar Hussain, Ane Haaland
AIMS: To explore and describe perceptions and experiences of living with type 1 Diabetes Mellitus among children/youths in Tajikistan. METHODS: Qualitative methods were employed. Participants were recruited through purposive and snowball samplings. Data were collected using a semi-structured interview guide with children/youths having diabetes, their parents as well as health professionals. Data were analyzed according to Malterud's systematic text condensation...
September 10, 2016: Chronic Illness
https://www.readbyqxmd.com/read/27588064/moyamoya-disease-manifested-as-multiple-simultaneous-intracerebral-hemorrhages-a-case-report-and-literature-review
#14
Jinlu Yu, Yongjie Yuan, Wei Li, Kan Xu
Multiple simultaneous intracerebral hemorrhages (MSIH) caused by Moyamoya disease (MMD) is extremely rare. To date, the clinical manifestations, imaging characteristics and mechanism of MMD-induced MSIH have not yet been elucidated. In order to improve the understanding on such cases, the present study described a rare case of MSIH caused by MMD. A 40-year-old female patient with no history of hypertension or diabetes mellitus experienced a sudden headache followed by coma. Cranial computed tomography (CT) examination revealed MSIH in the left frontal area, temporal lobe and basal ganglia...
September 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27532610/low-physical-activity-and-its-association-with-diabetes-and-other-cardiovascular-risk-factors-a-nationwide-population-based-study
#15
Laura Brugnara, Serafín Murillo, Anna Novials, Gemma Rojo-Martínez, Federico Soriguer, Albert Goday, Alfonso Calle-Pascual, Luis Castaño, Sonia Gaztambide, Sergio Valdés, Josep Franch, Conxa Castell, Joan Vendrell, Roser Casamitjana, Anna Bosch-Comas, Elena Bordiú, Rafael Carmena, Miguel Catalá, Elias Delgado, Juan Girbés, Alfonso López-Alba, Maria Teresa Martínez-Larrad, Edelmiro Menéndez, Inmaculada Mora-Peces, Gemma Pascual-Manich, Manuel Serrano-Ríos, Ramon Gomis, Emilio Ortega
Low physical activity (PA), or sedentary lifestyle, is associated with the development of several chronic diseases. We aimed to investigate current prevalence of sedentariness and its association with diabetes and other cardiovascular risk factors. PA was evaluated in a population-based, cross-sectional, randomly sampled study conducted in 2009-2010 in Spain. International Physical Activity Questionnaire (SF-IPAQ) was used to assess PA. 4991 individuals (median age 50 years, 57% women) were studied. Prevalence of sedentariness was 32...
2016: PloS One
https://www.readbyqxmd.com/read/27530120/race-specific-predictors-of-mortality-in-intracerebral-hemorrhage-differential-impacts-of-intraventricular-hemorrhage-and-age-among-blacks-and-whites
#16
Roland Faigle, Elisabeth B Marsh, Rafael H Llinas, Victor C Urrutia, Rebecca F Gottesman
BACKGROUND: Intracerebral hemorrhage (ICH) carries high risk for short-term mortality. We sought to identify race-specific predictors of mortality in ICH patients. METHODS AND RESULTS: We used 2 databases, the Johns Hopkins clinical stroke database and the Nationwide Inpatient Sample (NIS). We included 226 patients with the primary diagnosis of spontaneous ICH from our stroke database between 2010 and 2013; in the NIS, 42 077 patients met inclusion criteria. Logistic regression was used to assess differences in predictors of mortality in blacks compared to whites...
August 16, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27495047/the-outcomes-of-patients-with-severe-dengue-admitted-to-intensive-care-units
#17
Chin-Ming Chen, Khee-Siang Chan, Wen-Liang Yu, Kuo-Chen Cheng, Hui-Chun Chao, Chiu-Yin Yeh, Chih-Cheng Lai
Outcomes of adult patients with dengue infections requiring intensive care unit (ICU) admissions remain unclear. We assessed the clinical manifestations and prognostic factors of patients critically ill with severe dengue.This retrospective study was done in a tertiary referral hospital with 96 adult ICU beds. All of the patients with laboratory-confirmed severe dengue infections and admitted to the ICU were enrolled between July 31 and November 31, 2015, during the large outbreak period. The medical records of all the recruited patients were reviewed for the following information: age, gender, clinical manifestations, disease severity scores, underlying conditions, laboratory examinations, and outcomes...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27487367/expert-consensus-on-the-use-of-liraglutide-in-the-treatment-of-diabetes-in-internal-medicine
#18
Carlos Calvo Gómez, Ricardo Gómez-Huelgas, Joan Lima Ruiz, Lluis Masmiquel Comas, Alfredo Michán Doña, Antonio Zapatero Gaviria
BACKGROUND: Type 2 diabetes mellitus (DM2) is a disease of epidemic proportions. In the adult Spanish population, prevalence of DM2 is nearly 14%, which makes its monitoring and treatment imperative. Liraglutide has achieved relevance due to its efficacy and safety in DM treatment. The aim of this study is to gather expert opinion on diabetes to assess the current role of liraglutide in DM2. MATERIALS/METHODS: The survey was performed by 57 internal medicine specialists using the Delphi method...
November 2016: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27399391/111%C3%A2-predictors-of-complications-after-clipping-of-unruptured-intracranial-aneurysms-a-national-surgical-quality-improvement-program-analysis
#19
Hormuzdiyar H Dasenbrock, Robert F Rudy, William B Gormley, Timothy R Smith, Kai U Frerichs, Mohammad Ali Aziz-Sultan, Rose Du
INTRODUCTION: While obliteration of unruptured aneurysms reduces the risk of subarachnoid hemorrhage, perioperative complications impact the risk-benefit ratio of aneurysm repair, and additional data are needed to optimally risk-stratify patients preoperatively. METHODS: Patients who underwent craniotomy for microsurgical clipping of an unruptured aneurysm were extracted from the prospective National Surgical Quality Improvement Program (NSQIP) registry (2007-2014)...
August 2016: Neurosurgery
https://www.readbyqxmd.com/read/27398944/acute-ischaemic-hepatitis-secondary-to-acute-portal-system-thrombosis-triggered-by-diabetic-ketoacidosis-rare-presentation-of-acute-ischaemic-hepatitis
#20
E Tas, S Atlanoglu, K T Onbasi, B Tas, A O Harmanci
Hypotension, hypoxia or hypotension and hypoxia together may proceed to ischaemic hepatitis; hypotension is often as a result of cardiovascular diseases. Ischaemic hepatitis not due to cirrhotic process or malignancy but due to acute thrombosis of the portal venous system is rare. In this article, we present a case of acute ischaemic hepatitis due to an acute thrombus developing after a ketoacidosis coma which was thought to have triggered this event. Other reasons which could be have triggered this event, such as a thrombophilia and cirrhosis or malignancy, were excluded...
December 16, 2015: West Indian Medical Journal
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