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Mohammad Soleimani

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https://www.readbyqxmd.com/read/28608561/angiogenic-and-restorative-ability-of-human-mesenchymal-stem-cells-were-reduced-following-treatment-with-serum-from-diabetes-mellitus-type-2-patients
#1
Jafar Rezaie, Malek Soleimani Mehranjani, Reza Rahbarghazi, Mohammad Ali Shariatzadeh
This experiment investigated the impact of serum from patients with type 2 diabetes mellitus on the angiogenic behavior of human mesenchymal stem cells in vitro. Changes in the level of Ang-1, Ang-2, cell migration and trans-differentiation into pericytes and endothelial lineage were monitored after 7 days. The interaction of mesenchymal stem cells with endothelial cells were evaluated using surface plasmon resonance technique. Paracrine restorative effect of diabetic stem cells was tested on pancreatic β cells...
June 13, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28601197/a-comparative-study-to-evaluate-myogenic-differentiation-potential-of-human-chorion-versus-umbilical-cord-blood-derived-mesenchymal-stem-cells
#2
Nikoo Bana, Davood Sanooghi, Mansoureh Soleimani, Nasim Hayati Roodbari, Sepideh Alavi Moghaddam, Mohammad Taghi Joghataei, Forough Azam Sayahpour, Faezeh Faghihi
OBJECTIVE: Musculodegenerative diseases threaten the life of many patients in the world. Since drug administration is not efficient in regeneration of damaged tissues, stem cell therapy is considered as a good strategy to restore the lost cells. Since the efficiency of myogenic differentiation potential of human Chorion- derived Mesenchymal Stem Cells (C-MSCs) has not been addressed so far; we set out to evaluate myogenic differentiation property of these cells in comparison with Umbilical Cord Blood- derived Mesenchymal Stem Cells (UCB-MSCs) in the presence of 5-azacytidine...
May 11, 2017: Tissue & Cell
https://www.readbyqxmd.com/read/28601053/species-identification-and-prevalence-of-house-dust-mites-as-respiratory-allergen-in-kindergartens-of-the-bandar-abbas-city
#3
Moussa Soleimani-Ahmadi, Mehdi Zare, Seyyed Mohammad Abtahi, Atefe Khazeni
The aim of this study was to identify the species and prevalence of house dust mites (HDMs) in kindergartens in Bandar Abbas, south of Iran. In this study 10 kindergartens were selected randomly in five areas of Bandar Abbas. Two dust samples were collected from each sampling place with a vacuum cleaner. Mites were isolated and mounted in Hoyer's medium and identified using a morphology-based key. In total, 1758 mites were collected and identified, whichconsisted of five species: Dermatophagoides pteronyssinus (31...
April 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/28580309/up-regulation-of-foxc2-and-foxq1-is-associated-with-the-progression-of-gastric-type-adenocarcinoma
#4
Farzad Soleimani, Mohammadreza Hajjari, Bahram Mohammad Soltani, Mehrdad Behmanesh
OBJECTIVE: Forkhead box (FOX) proteins are important regulators of the epithelial-to-mesenchymal transition (EMT), which is the main mechanism of cancer metastasis. Different studies have shown their potential involvement in progression of cancer in different tissues such as breast, ovary and colorectum. In this study, we aimed to analyze the expression of genes encoding two FOX proteins in gastric adenocarcinoma. MATERIALS AND METHODS: In this experimental case-control study, the expression of FOXC2 and FOXQ1 was examined in 31 gastric adenocarcinoma tumors and 31 normal adjacent gastric tissues by reverse transcription polymerase chain reaction (PCR)...
2017: Cell Journal
https://www.readbyqxmd.com/read/28537049/laser-treatment-for-urethral-hemangiomas-report-of-three-cases
#5
Mohammad Javad Soleimani, Pejman Shadpour, Kaveh Mehravaran, Amir Hossein Kashi
To present our experience with coagulation/laser treatment of urethral hemangiomas. Three cases with small to medium sized urethral hemangiomas in penile and posterior urethra presented with hematuria or urethral bloody discharge. All patients were male. They were treated with thermal or Nd-YAG laser coagulation in the first session. Recurrence of hematuria/bloody discharge happened in two patients within one month from the first treatment that was managed with a second session of laser coagulation. No third session of intervention for hematuria/bloody discharge was required in any patient during 10-39 months of follow up...
May 23, 2017: Urology Journal
https://www.readbyqxmd.com/read/28526349/in-vivo-evaluation-of-toxicity-and-antiviral-activity-of-polyrhodanine-nanoparticles-by-using-the-chicken-embryo-model
#6
Ahmad Nazaktabar, Mohammad Soleimani Lashkenari, Atefeh Araghi, Mohsen Ghorbani, Hannaneh Golshahi
Evaluation of the potential cytotoxicity of polyrhodanine nanoparticles is an important factor for its biological applications. In current study, for the first time histopathological and biochemical analysis of polyrhodanine besides of its antiviral activity against Newcastle disease virus (NDV) were examined on chicken embryo model. Polyrhodanine was synthesized by the chemical oxidative polymerization method. The obtained nanoparticles were characterized by scanning electron microscopy (SEM), and Fourier transform infrared (FTIR)...
May 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28506774/immunomodulatory-and-protective-effects-of-adipose-tissue-derived-mesenchymal-stem-cells-in-an-allograft-islet-composite-transplantation-for-experimental-autoimmune-type-1-diabetes
#7
Jamal Mohammadi Ayenehdeh, Bahare Niknam, Shima Rasouli, Seyed Mahmoud Hashemi, Hossein Rahavi, Nima Rezaei, Masoud Soleimani, Ali Liaeiha, Mohammad Hossein Niknam, Nader Tajik
BACKGROUND: Allogeneic islet transplantation could be an ideal alternative therapy for Type 1 Diabetes Mellitus (T1DM). Adipose Tissue-derived Mesenchymal Stem Cells (AT-MSCs) characterized by immunomodulatory and protective effects may have the potential to improve the outcome of this highly immunogenic transplant. METHODS: Syngenic AT-MSCs along with allograft islets embedded in hydrogelic composite and transplanted intraperitoneally in Streptozotocin (STZ) induced diabetic C57BL/6 mice...
May 12, 2017: Immunology Letters
https://www.readbyqxmd.com/read/28500662/application-of-a-novel-bioreactor-for-in-vivo-engineering-of-pancreas-tissue
#8
Javad Hashemi, Parvin Pasalar, Masoud Soleimani, Reza Khorramirouz, Kiarad Fendereski, Seyed Ehsan Enderami, Abdol-Mohammad Kajbafzadeh
Type 1 diabetes is characterized by autoimmune destruction of pancreatic cells. Organ transplantation is an acceptable treatment for native organ failure. However, it is associated with several problems due to a number of reasons, such as the lack of appropriate donors and immunosuppression. In our present study, a novel model is presented for in vivo recellularization of acellular pancreas by implanting between the host pancreas and the adjacent omental flap. In this study, the pancreases were harvested and cannulated via the common bile duct and then, the scaffolds were acellularized by a detergent-based protocol...
May 13, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28497085/evaluation-of-water-and-electrolytes-disorders-in-severe-acute-diarrhea-patients-treated-by-who-protocol-in-eight-large-hospitals-in-tehran-a-nephrology-viewpoint
#9
Alireza Soleimani, Fatemeh Foroozanfard, Mohammad Reza Tamadon
Introduction: The most common cause of death from diarrhea is the shock caused by dehydration, electrolytes and acid-base disorders. Objectives: The aim of this study was to evaluate water and electrolytes disorders in diarrhea patients after treating severe acute diarrhea. Patients and Methods: In this study we used a historical cohort and studied patients who were hospitalized due to acute diarrhea and were similarly treated for dehydration and water and electrolyte disorders as recommended by the World Health Organization (WHO) guideline...
2017: Journal of Renal Injury Prevention
https://www.readbyqxmd.com/read/28493817/the-relationship-between-anxiety-depression-and-risk-behaviors-in-adolescents
#10
Mohammad Ali Soleimani, Saeed Pahlevan Sharif, Nasim Bahrami, Ameneh Yaghoobzadeh, Kelly A Allen, Sepideh Mohammadi
Aim Adolescence is a developmental period often associated with high-risk behaviors. While some risk-taking behavior is considered normative in adolescents, research has indicated an association between risky behaviors and mental ill-health. The current research aimed to examine the relationship between anxiety and depression with the occurrence of high-risk behaviors in adolescents and also determine the predictive factors of these main variables. Methods A descriptive, cross-sectional, correlational design was used to collect data from 399 adolescents between the ages of 14 and 19 residing in Qazvin, Iran using the Revised Child Anxiety and Depression Scale (RCADS) and the Iranian Adolescents Risk-taking Scale (IARS) between the period of October and November 2015...
May 11, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28415542/bladder-smooth-muscle-cells-on-electrospun-poly-%C3%AE%C2%B5-caprolactone-poly-l-lactic-acid-scaffold-promote-bladder-regeneration-in-a-canine-model
#11
Nasser Shakhssalim, Masoud Soleimani, Mohammad M Dehghan, Javad Rasouli, Masoud Taghizadeh-Jahed, Peyman M Torbati, Mohammad Naji
Engineering of urinary bladder has been the focus of numerous studies in recent decade. Novel biomaterials, innovative fabrication methods and various modification processes of scaffolds are the critical issues to find supportive matrices. Supportive characteristics of electrospun PCL/PLLA nano-scaffold for bladder augmentation in canine model and the role of bladder cells in regeneration process were appraised. Electrospun PCL/PLLA was fabricated by co-electrospinning of PCL and PLLA. Bladder cells were isolated and transduced with lentiviral particles encoding eGFP and JRed proteins...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28415516/acceleration-of-bone-regeneration-in-bioactive-glass-gelatin-composite-scaffolds-seeded-with-bone-marrow-derived-mesenchymal-stem-cells-over-expressing-bone-morphogenetic-protein-7
#12
Saeid Kargozar, Seyed Jafar Hashemian, Mansooreh Soleimani, Peiman Brouki Milan, Mohammad Askari, Vahid Khalaj, Ali Samadikuchaksaraie, Sepideh Hamzehlou, Amir Reza Katebi, Noorahmad Latifi, Masoud Mozafari, Francesco Baino
In this research, the osteoinduction effect of a novel variant of bone morphogenetic protein-7 (BMP-7), delivered through bone marrow mesenchymal stem cells (BM-MSCs) seeded on bioactive glass/gelatin nanocomposite scaffolds, was evaluated in a calvarial critical size defect in rats. After being harvested and characterized in vitro, BM-MSCs were infected by a plasmid vector containing BMP-7 encoding gene enriched with a heparin-binding site (B2BMP-7) to assess its osteogenic effects in vivo. The animals were randomly categorized into three groups receiving the scaffold alone (group I), the scaffold seeded with BM-MSCs (group II), and the scaffold seeded with manipulated BM-MSCs (group III)...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28411308/the-effect-of-mir-200c-inhibition-on-chemosensitivity-5-fluorouracil-in-colorectal-cancer
#13
Korosh Heydari, Massoud Saidijam, Mohammad Reza Sharifi, Fatemeh Karimi Dermani, Sara Soleimani Asl, Nooshin Shabab, Rezvan Najafi
5-Fluorouracil (5-FU) as a chemotherapeutic drug is used to treat colorectal cancer (CRC). However, 5-FU is associated with acquired CRC resistance, which decreases the therapeutic potential of 5-FU. Several studies indicated that miR-200c is also involved in chemotherapeutic drug resistance, but the exact mechanism of miR-200c mediated chemoresistance has not yet been fully understood. In this study, we examined the effect of inhibition of miR-200c on the sensitivity of HCT-116 cells to 5-FU. HCT-116 cells were transfected with LNA-anti- miR-200c for 48 h...
April 14, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28385341/enhancement-of-%C3%AE-opioid-receptor-desensitization-by-orexin-a-in-rat-locus-coeruleus-neurons
#14
S Mohammad Ahmadi Soleimani, Hossein Azizi, Narges Pachenari, Javad Mirnajafi-Zadeh, Saeed Semnanian
Opioids have always been used in clinical practice for pain management. However, development of tolerance to their effects following long term administration, seriously restricts further clinical use of these drugs. In this regard, μ-opioid receptor (MOR) desensitization, as an initial step in development of opioid tolerance, is of particular significance. Previous studies support the involvement of orexinergic system in development of opioid tolerance. Locus coeruleus (LC) nucleus has been shown to modulate pain and development of tolerance...
March 23, 2017: Neuropeptides
https://www.readbyqxmd.com/read/28358750/bird-attack-ocular-injuries
#15
Seyed Ali Tabatabaei, Mohammad Soleimani, Mahmoud Jabbarvand Behrouz
BACKGROUND/PURPOSE: To report 30 patients with bird attack-related eye injuries. METHODS: This study was performed among patients coming to Farabi Eye Hospital, Tehran, Iran, from 2010 to 2015 with a history of bird attack causing eye injury. The inclusion criteria were a history of bird attack by pecking causing eye injury and having treatment and follow-up record for at least 6 months after treatment. The primary eye examinations included a full ophthalmic examination including evaluation of uncorrected visual acuity and best-corrected visual acuity (BCVA), anterior segment slit lamp biomicroscopy, and photography...
March 29, 2017: Retina
https://www.readbyqxmd.com/read/28351499/retina-tissue-engineering-by-conjunctiva-mesenchymal-stem-cells-encapsulated-in-fibrin-gel-hypotheses-on-novel-approach-to-retinal-diseases-treatment
#16
Mostafa Soleimannejad, Somayeh Ebrahimi-Barough, Samad Nadri, Mohammad Riazi-Esfahani, Masoud Soleimani, Seyed Mohammad Tavangar, Jafar Ai
BACKGROUND: Retinitis pigmentosa (RP) and age related macular degeneration (AMD) are two retinal diseases that progress by photoreceptor cells death. In retinal transplantation studies, stem and progenitor cells inject into the sub retinal space or vitreous and then these cells can be migrate to the site of retinal degeneration and locate in the host retina and restitute vision. PRESENTATION OF THE HYPOTHESIS: Our hypothesis suggests that using human conjunctiva stem cells (as the source for increasing the number of human stem cells progenitor cells in retina dysfunction diseases) with fibrin gel and also assessing its relating in vitro (cellular and molecular processes) and in vivo (vision tests and pathology) could be a promising strategy for treatment of AMD and RP disorders...
April 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28321826/the-role-of-probiotics-in-the-treatment-of-dysentery-a-randomized-double-blind-clinical-trial
#17
Alireza Sharif, Hamed Haddad Kashani, Elahe Nasri, Zahra Soleimani, Mohammad Reza Sharif
Diarrhea is considered as an important cause of morbidity and mortality, even though one of the main reasons of death following diarrhea is initiated by dysentery. In recent years, the consumption of probiotics has been proposed for the treatment of infectious diarrhea. Despite most of the studies on probiotics have focused on acute watery diarrhea, few studies in the field of dysentery have found beneficial effects of probiotics. This study is a randomized double-blind clinical trial. The patients were randomly placed into control and case groups...
March 21, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28298637/hybrid-magnetic-dna-directed-immobilisation-approach-for-efficient-protein-capture-and-detection-on-microfluidic-platforms
#18
Elaheh Esmaeili, Mohammad Adel Ghiass, Manouchehr Vossoughi, Masoud Soleimani
In this study, a hybrid magnetic-DNA directed immobilisation approach is presented to enhance protein capture and detection on a microfluidic platform. DNA-modified magnetic nanoparticles are added in a solution to capture fluorescently labelled immunocomplexes to be detected optically. A magnetic set-up composed of cubic permanent magnets and a microchannel was designed and implemented based on finite element analysis results to efficiently concentrate the nanoparticles only over a defined area of the microchannel as the sensing zone...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28290050/micellar-nano-carriers-for-the-delivery-of-stat3-dimerization-inhibitors-to-melanoma
#19
Amir H Soleimani, Shyam M Garg, Igor M Paiva, Mohammad R Vakili, Abdulraheem Alshareef, Yung-Hsing Huang, Ommoleila Molavi, Raymond Lai, Afsaneh Lavasanifar
The objective of this research was to develop polymeric micellar formulations of inhibitors of signal transducer and activator of transcription 3 (STAT3) dimerization, i.e., S3I-1757 and S3I-201, and evaluate the activity of successful formulations in B16-F10 melanoma, a STAT3 hyperactive cancer model, in vitro and in vivo. STAT3 inhibitory agents were encapsulated in methoxy poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO114-b-PCL22) and methoxy poly(ethylene oxide)-b-poly(α-benzyl carboxylate-ε-caprolactone) (PEO114-b-PBCL20) micelles using co-solvent evaporation...
March 13, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/28287811/two-triacylglycerol-pathway-genes-ctdnep1-and-lpin1-are-down-regulated-by-hsa-mir-122-5p-in-hepatocytes
#20
Mahmood Naderi, Abdolreza Pazouki, Ehsan Arefian, Seyed Mahmoud Hashemi, Fatemeh Jamshidi-Adegani, Omid Gholamalamdari, Sara Soudi, Kayhan Azadmanesh, Siamak Mirab Samiee, Shahin Merat, Mohammad Gholami Fesharaki, Mahdieh Mondanizadeh, Mohammad Vasei, Masoud Soleimani
BACKGROUND: Expression of miR-122 is highly specific to hepatocytes of the liver.  This miRNA is involved in lipid hemostasis of the tissue; however, there is no comprehensive understanding of its function in lipid hemostasis. MATERIALS AND METHODS: Since hepatocytes are responsible for part of Triacylglycerol (TAG) synthesis in the body, we hypothesized that miR-122, as the most abundant miRNA in the tissue, might regulate TAG metabolism by targeting key enzymes that are involved in its production pathway...
March 2017: Archives of Iranian Medicine
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