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Mohammad Soleimani

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https://www.readbyqxmd.com/read/28298637/hybrid-magnetic-dna-directed-immobilisation-approach-for-efficient-protein-capture-and-detection-on-microfluidic-platforms
#1
Elaheh Esmaeili, Mohammad Adel Ghiass, Manouchehr Vossoughi, Masoud Soleimani
In this study, a hybrid magnetic-DNA directed immobilisation approach is presented to enhance protein capture and detection on a microfluidic platform. DNA-modified magnetic nanoparticles are added in a solution to capture fluorescently labelled immunocomplexes to be detected optically. A magnetic set-up composed of cubic permanent magnets and a microchannel was designed and implemented based on finite element analysis results to efficiently concentrate the nanoparticles only over a defined area of the microchannel as the sensing zone...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28290050/micellar-nano-carriers-for-the-delivery-of-stat3-dimerization-inhibitors-to-melanoma
#2
Amir H Soleimani, Shyam M Garg, Igor M Paiva, Mohammad R Vakili, Abdulraheem Alshareef, Yung-Hsing Huang, Ommoleila Molavi, Raymond Lai, Afsaneh Lavasanifar
The objective of this research was to develop polymeric micellar formulations of inhibitors of signal transducer and activator of transcription 3 (STAT3) dimerization, i.e., S3I-1757 and S3I-201, and evaluate the activity of successful formulations in B16-F10 melanoma, a STAT3 hyperactive cancer model, in vitro and in vivo. STAT3 inhibitory agents were encapsulated in methoxy poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO114-b-PCL22) and methoxy poly(ethylene oxide)-b-poly(α-benzyl carboxylate-ε-caprolactone) (PEO114-b-PBCL20) micelles using co-solvent evaporation...
March 13, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/28287811/two-triacylglycerol-pathway-genes-ctdnep1-and-lpin1-are-down-regulated-by-hsa-mir-122-5p-in-hepatocytes
#3
Mahmood Naderi, Abdolreza Pazouki, Ehsan Arefian, Seyed Mahmoud Hashemi, Fatemeh Jamshidi-Adegani, Omid Gholamalamdari, Sara Soudi, Kayhan Azadmanesh, Siamak Mirab Samiee, Shahin Merat, Mohammad Gholami Fesharaki, Mahdieh Mondanizadeh, Mohammad Vasei, Masoud Soleimani
BACKGROUND: Expression of miR-122 is highly specific to hepatocytes of the liver.  This miRNA is involved in lipid hemostasis of the tissue; however, there is no comprehensive understanding of its function in lipid hemostasis. MATERIALS AND METHODS: Since hepatocytes are responsible for part of Triacylglycerol (TAG) synthesis in the body, we hypothesized that miR-122, as the most abundant miRNA in the tissue, might regulate TAG metabolism by targeting key enzymes that are involved in its production pathway...
March 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/28218044/leukemia-microvesicles-affect-healthy-hematopoietic-stem-cells
#4
Farnaz Razmkhah, Masoud Soleimani, Davood Mehrabani, Mohammad Hossein Karimi, Sedigheh Amini Kafi-Abad, Mani Ramzi, Mahdiyar Iravani Saadi, Javad Kakoui
Microvesicles are released by different cell types and shuttle mRNAs and microRNAs which have the possibility to transfer genetic information to a target cell and alter its function. Acute myeloid leukemia is a malignant disorder, and leukemic cells occupy all the bone marrow microenvironment. In this study, we investigate the effect of leukemia microvesicles on healthy umbilical cord blood hematopoietic stem cells to find evidence of cell information transferring. Leukemia microvesicles were isolated from acute myeloid leukemia patients and were co-incubated with healthy hematopoietic stem cells...
February 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28188050/successful-treatment-with-caspofungin-of-candiduria-in-a-child-with-wilms-tumor-review-of-literature
#5
M S Rezai, A Vaezi, H Fakhim, A Soleimani, H Mohammad Jafari, S Mohseni, H Badali
Symptomatic candiduria often occurs in patients with indwelling bladder catheters or immunocompromised host. Isolation of Candida in urine in high-risk patients should primarily be considered as a marker for candidemia. Hematological and genitourinary malignancies are one of the main risk factors associated with Candida urinary tract infections (CUTI). Fluconazole is a choice for initial treatment of CUTI, but it is fluctuate depending on the patient's condition including renal failure, site of urinary infection and Candida species...
February 7, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/28150578/resistotyping-phenotyping-and-genotyping-of-new-delhi-metallo-%C3%AE-lactamase-ndm-among-gram-negative-bacilli-from-iranian-patients
#6
Dariush Shokri, Mohammad Rabbani Khorasgani, Seyed Masih Fatemi, Abbas Soleimani-Delfan
PURPOSE: The purpose of this study was investigation of New Delhi metallo-β-lactamase (NDM) production among gram negative bacilli. METHODOLOGY: Antibiogram-Resistotyping and detection of NDM in clinical isolates of Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa and comparative evaluation of the diagnostic performance of three phenotypic methods for NDM detection considering PCR as gold standard were performed. Minimum Inhibitory Concentration (MIC) of antibiotics against NDM positive strains by E-test and clonal relationship analysis using Enterobacterial Repetitive Intergenic Consensus Polymerase Chain Reaction (ERIC-PCR) in these strains were determined...
February 1, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28149491/evidence-of-human-coroanvirus-229e-in-patients-with-respiratory-infection-iran-2015-the-first-report
#7
Ali Madhi, Arash Ghalyanchilangeroudi, Mohammad Soleimani
BACKGROUND AND OBJECTIVES: Human coronaviruses (HCoVs) are one of the main causes of upper respiratory tract infections in humans. While more often responsible for mild illness, they have been associated with illnesses that require hospitalization. MATERIALS AND METHODS: 270 Samples from patients hospitalized with the respiratory infection during the autumn season of 2015 were evaluated for the presence of four HCoVs (OC43, 229E, HUK1, and NL63) using an optimized SYBR green RT-PCR assay...
October 2016: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/28146367/corneal-involvement-by-lichen-planus-pigmentosus
#8
Mohammad Soleimani, Seyed Ali Tabatabaei, Reza Mirshahi, Zohreh Nozarian, Amir Hasan Matini
IMPORTANCE: Lichen planus pigmentosus (LPP) is an exclusive form of lichen planus (LP) characterized by pigmentary incontinence in histopathologic slides. OBSERVATIONS: We report a known case of LPP with ocular manifestations including pigmented eyelid margins and conjunctival and corneal pigmented lesions. Histopathologic and confocal scanning findings of these lesions were compatible with the diagnosis of underlying systemic disease. CONCLUSIONS AND RELEVANCE: To our knowledge, we report the first case of cornea directly involved by LP and ophthalmic presentations of LPP...
February 1, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28131677/a-randomized-clinical-trial-to-evaluate-the-usefulness-of-amniotic-membrane-transplantation-in-bacterial-keratitis-healing
#9
Seyed Ali Tabatabaei, Mohammad Soleimani, Mahmoud Jabbarvand Behrouz, Ali Torkashvand, Pasha Anvari, Mehdi Yaseri
PURPOSE: To determine whether early amniotic membrane transplantation improves the outcomes among patients with bacterial keratitis. PATIENTS AND METHODS: In this prospective randomized clinical trial 49 eyes from 49 patients with bacterial keratitis received routine antibiotic therapy followed by double-layer amniotic membrane transplantation during 2-5 days after start up of the medications and the second group of 50 eyes from 50 patients only received routine antibacterial therapy...
January 25, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28116894/enhanced-cardiac-differentiation-of-human-cardiovascular-disease-patient-specific-induced-pluripotent-stem-cells-by-applying-unidirectional-electrical-pulses-using-aligned-electroactive-nanofibrous-scaffolds
#10
Leila Mohammadi Amirabad, Mohammad Massumi, Mehdi Shamsara, Iman Shabani, Afshin Amari, Majid Mossahebi Mohammadi, Simzar Hosseinzadeh, Saeid Vakilian, Sarah K Steinbach, Mohammad R Khorramizadeh, Masoud Soleimani, Jalal Barzin
In the embryonic heart, electrical impulses propagate in a unidirectional manner from the sinus venosus and appear to be involved in cardiogenesis. In this work, aligned and random polyaniline/polyetersulfone (PANI/PES) nanofibrous scaffolds doped by Camphor-10-sulfonic acid (β) (CPSA) were fabricated via electrospinning and used to conduct electrical impulses in a unidirectional and multidirectional fashion, respectively. A bioreactor was subsequently engineered to apply electrical impulses to cells cultured on PANI/PES scaffolds...
March 1, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28093335/intracoerulear-microinjection-of-orexin-a-induces-morphine-withdrawal-like-signs-in-rats
#11
Masoumeh Ghaemi-Jandabi, Hossein Azizi, S Mohammad Ahmadi-Soleimani, Saeed Semnanian
Orexin (hypocretin) neuropeptides play a pivotal role in expression of opioid withdrawal signs. Hypothalamic orexinergic neurons provide dense afferents for the nucleus locus coeruleus (LC). Somatic signs of opioid withdrawal are associated with the enhanced activity of LC neurons. In addition, intra-LC administration of orexin-A leads to the hyperactivity of LC neurons. The present study was an attempt to investigate whether intra-LC microinjection of orexin-A induces morphine withdrawal-like signs in both morphine dependent and control rats...
January 16, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28058748/effect-of-acupressure-on-pain-in-iranian-leukemia-patients-a-randomized-controlled-trial-study
#12
Hamid Sharif Nia, Saeed Pahlevan Sharif, Ameneh Yaghoobzadeh, Ken Kyid Yeoh, Amir Hossein Goudarzian, Mohammad Ali Soleimani, Saman Jamali
Nonpharmacological methods of pain relief such as acupressure are becoming increasingly popular worldwide. Practitioners often claim that such methods are highly effective and less invasive than analgesic drugs, but available empirical evidence is largely inconclusive. This study aimed to test the hypothesis that, postacupressure intervention, the amount of pain experienced by sampled leukemia patients, who received acupressure in addition to standard care, will reduce substantially compared to patients who received only routine treatment...
January 6, 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/28043575/rapid-identification-of-mycobacterium-avium-ssp-paratuberculosis-laboratory-strains-by-is900-nested-polymerase-chain-reaction
#13
Mohammad Mohammad Taheri, Nader Mosavari, Mohammad Mehdi Feizabadi, Keyvan Tadayon, Rouholah Keshavarz, Reza Aref Pajoohi, Kioomars Soleimani, Shojaat Dashti Pour
INTRODUTION: Mycobacterium avium ssp paratuberculosis (MAP) causes paratuberculosis (Johne's disease) in ruminants. As a species, M. avium comprises M. avium subsp. hominissuis and a number of clones that are known to have evolved from this subspecies, namely M. avium subsp. avium (MAA), M. avium subsp. silvaticum, and MAP. Despite the very high genomic similarity of MAP and MAA, the insertion sequence IS900, which is 1,451-bp long, is now understood to be exclusively present in 10-20 copies in the genome of MAP...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28042549/relationship-between-il-17-serum-level-and-ambulatory-blood-pressure-in-women-with-polycystic-ovary-syndrome
#14
Fatemeh Foroozanfard, Alireza Soleimani, Elham Arbab, Mansooreh Samimi, Mohammad Reza Tamadon
BACKGROUND: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders with an inflammatory basis. It is associated with hyperandrogenism in women and can be also associated with increased activity of the renin-angiotensin system (RAS). Approximately 5% to 10% of women of reproductive age are affected by this disease. This syndrome is the main cause of infertility. Blood pressure may be one of the complications of the syndrome. OBJECTIVES: In this study, we sought to assess the role of the IL-17 inflammatory cytokine in increasing blood pressure in patients with PCOS...
January 2017: Journal of Nephropathology
https://www.readbyqxmd.com/read/28039620/primordial-germ-cell-differentiation-of-nuclear-transfer-embryonic-stem-cells-using-surface-modified-electroconductive-scaffolds
#15
Tarlan Eslami-Arshaghi, Saeid Vakilian, Ehsan Seyedjafari, Abdolreza Ardeshirylajimi, Masoud Soleimani, Mohammad Salehi
A combination of nanotopographical cues and surface modification of collagen and fibronectin is a potential platform in primordial germ cells (PGCs) differentiation. In the present study, the synergistic effect of nanotopography and surface modification on differentiation of nuclear transfer embryonic stem cells (nt-ESCs) toward PGC lineage was investigated. In order to achieve this goal, poly-anyline (PANi) was mix within poly-L-lactic acid (PLLA). Afterward, the random composite mats were fabricated using PLLA and PANi mix solution...
December 30, 2016: In Vitro Cellular & Developmental Biology. Animal
https://www.readbyqxmd.com/read/28007011/mimicking-the-acute-myeloid-leukemia-niche-for-molecular-study-and-drug-screening
#16
Mohammad Houshmand, Masoud Soleimani, Amir Atashi, Giuseppe Saglio, Mohammad Abdollahi, Mahin Nikougoftar Zarif
Bone marrow niche is a major contributing factor in leukemia development and drug resistance in acute myeloid leukemia (AML) patients. Although mimicking leukemic bone marrow niche relies on two-dimensional (2D) culture conditions, it cannot recapitulate complex bone marrow structure that causes introduction of different three-dimensional (3D) scaffolds. Simultaneously, microfluidic platform by perfusing medium culture mimic interstitial fluid flow, along with 3D scaffold would help for mimicking bone marrow microenvironment...
February 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28004353/association-of-ccnd1-gene-c-870g-a-polymorphism-with-breast-cancer-risk-a-case-controlstudy-and-a-meta-analysis
#17
Zahra Soleimani, Davood Kheirkhah, Mohammad Reza Sharif, Alireza Sharif, Mohammad Karimian, Younes Aftabi
Cyclin D1 (CCND1) plays an essential role in regulating the progress of the cell cycle from G1 to S phase. There is a common c.870G>A polymorphism in the CCND1 gene. The aim of this study was to investigate the association of CCND1 gene c.870G>A polymorphism with breast cancer risk in a case-control study, which followed by a meta-analysis and an in silico analysis. Three hundred and thirty-five subjects composed of 174 women with breast cancer and 161 healthy controls were included in the case-control study...
December 21, 2016: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/27995589/comparative-of-fibroblast-and-osteoblast-cells-adhesion-on-surface-modified-nanofibrous-substrates-based-on-polycaprolactone
#18
Fereshteh Sharifi, Shiva Irani, Mojgan Zandi, Masoud Soleimani, Seyed Mohammad Atyabi
One of the determinant factors for successful bioengineering is to achieve appropriate nano-topography and three-dimensional substrate. In this research, polycaprolactone (PCL) nano-fibrous mat with different roughness modified with O2 plasma was fabricated via electrospinning. The purpose of this study was to evaluate the effect of plasma modification along with surface nano-topography of mats on the quality of human fibroblast (HDFs) and osteoblast cells (OSTs)-substrate interaction. Surface properties were studied using scanning electron microscopy (SEM), atomic force microscopy (AFM), contact angle, Fourier-transformation infrared spectroscopy...
December 2016: Progress in biomaterials
https://www.readbyqxmd.com/read/27987378/in-vitro-differentiation-of-neural-stem-cells-derived-from-human-olfactory-bulb-into-dopaminergic-like-neurons
#19
Rafieh Alizadeh, Gholamreza Hassanzadeh, Mohammad Taghi Joghataei, Mansoureh Soleimani, Fatemeh Moradi, Shahram Mohammadpour, Jahangir Ghorbani, Ali Safavi, Maryam Sarbishegi, Vahid Pirhajati Mahabadi, Leila Alizadeh, Mahmoudreza Hadjighassem
This study describes a new accessible source of neuronal stem cells that can be used in Parkinson's disease cell transplant. The human olfactory bulb contains neural stem cells (NSCs) that are responsible for neurogenesis in the brain and the replacement of damaged cellular components throughout life. NSCs are capable of differentiating into neuronal and glial cells. We isolated NSCs from the olfactory bulb of brain-death donors and differentiated them into dopaminergic neurons. The olfactory bulb tissues obtained were cultured in Dulbecco's modified Eagle's medium/nutrient mixture F12, B27 supplemented with basic fibroblast growth factor, epidermal growth factor and leukemia inhibitory factor...
December 17, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27981851/molecular-detection-of-aminoglycoside-modifying-enzyme-genes-in-acinetobacter-baumannii-clinical-isolates
#20
Mohsen Heidary, Alireza Salimi Chirani, Saeed Khoshnood, Gita Eslami, Seyyed Mohammad Atyabi, Habibollah Nazem, Mohammad Fazilati, Ali Hashemi, Saleh Soleimani
Acinetobacter baumannii is a major opportunistic pathogen in healthcare settings worldwide. In Iran, there are only few reports on the prevalence of aminoglycoside resistance genes among A. baumannii isolates. The aim of this study was to investigate the existence of aminoglycoside-modifying enzyme (AME) genes from A. baumannii strains collected at a university teaching hospital in Iran. One hundred A. baumannii strains were collected between 2014 and 2015 from hospitalized patients at Loghman Hakim Hospital, Tehran, Iran...
December 16, 2016: Acta Microbiologica et Immunologica Hungarica
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