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JOURNAL ARTICLE
Hamed Hesami, Serwa Ghasemi, Golnaz Houshmand, Yalda Nilipour, Mahshid Hesami, Alireza Biglari, Shahriar Nafissi, Majid Maleki, Samira Kalayinia
BACKGROUND: Limb girdle muscular dystrophies (LGMDs) constitute a heterogeneous group of neuromuscular disorders with a very variable clinical presentation and overlapping traits. The clinical symptoms of LGMD typically appear in adolescence or early adulthood. Genetic variation in the dysferlin gene (DYSF) has been associated with LGMD. METHODS: We characterized a recessive LGMD in a young adult from consanguineous Irani families using whole-exome sequencing (WES) technology...
March 27, 2024: BMC Musculoskeletal Disorders
#2
REVIEW
Sara Hashemi, Seyed Saman Hashemi, Kioumars Tavakoli Tafti, Seyed Sobhan Khademi, Niyosha Ariana, Shohreh Ghasemi, Mahmood Dashti, Hamed Ghanati, Marjan Mansourian
BACKGROUND: The objective is to compare the impact of clear aligner treatment (CAT) versus conventional fixed appliance treatment (FAT) on oral health-related quality of life (OHRQoL) among adults at five-time points: pretreatment (T0), 1 week (T1), 1 month after (T2), and 6 months after (T3) treatment initiation, and in the long-term follow-up (T4). MATERIALS AND METHODS: Search terms were based on Medical Subject Headings (MeSH) and non-MeSH. Potentially eligible studies compared OHRQoL in clear aligner (CA) and fixed appliance (FA) patients...
2024: Dental Research Journal
#3
REVIEW
Saber Zafarshamspour, Emal Lesha, Arba Cecia, Haydy George, Mohammad Ghasemi-Rad, Kelly Trinh, Shirin Yaghoobpoor, Hamed Ghorani, Mohammad E Majd, Keyvan Eghbal
Atlantoaxial rotatory fixation (AARF) in adults is a rare and clinically challenging condition characterized by a spectrum of etiological factors, predominantly attributed to traumatic and inflammatory pathologies within the craniovertebral region. Trauma is the most frequently identified cause within the adult population, with the first case report published in 1907. This study aims to conduct a systematic review that addresses the clinical presentations and management strategies relating to traumatic atlantoaxial rotatory fixation in adults...
February 20, 2024: Neurosurgical Review
#4
JOURNAL ARTICLE
Alireza Hashemi, Hassan Hashemi, Alireza Jamali, Hamed Ghasemi, Fatemeh Ghazizadeh Hashemi, Mehdi Khabazkhoob
To determine the association between visual impairment (VI) and some mental disorders using the general health questionnaire (GHQ) in individuals aged 60 years and above in Tehran, Iran. The present population-based cross-sectional study was conducted on people aged 60 and older in Tehran, Iran using multi-stage cluster sampling. After selecting the samples, examinations including visual acuity measurement, refraction, and slit-lamp biomicroscopy were performed for all participants. The GHQ was used to examine mental disorders...
January 27, 2024: Scientific Reports
#5
JOURNAL ARTICLE
Sajad Dekamin, Mehdi Ghasemi, Ahmad Reza Dehpour, Mahmoud Ghazi-Khansari, Hamed Shafaroodi
Chemotherapy-induced peripheral neuropathy (CIPN) is a major challenge for cancer patients who undergo chemotherapy with paclitaxel. Therefore, finding effective therapies for CIPN is crucial. Glatiramer acetate is used to treat multiple sclerosis that exerts neuroprotective properties in various studies. We hypothesized that glatiramer acetate could also improve the paclitaxel-induced peripheral neuropathy. We used a rat model of paclitaxel (2 mg/kg/every other day for 7 doses)-induced peripheral neuropathy...
January 22, 2024: Neurochemical Research
#6
Elham Khoshbin, Leila Ghasemi, Rezvan Najafi, Hamed Karkehabadi
No abstract text is available yet for this article.
December 27, 2023: Biotechnology Letters
#7
JOURNAL ARTICLE
Seyed Majid Mousavi Movahed, Hamed Akhavizadegan, Fatemeh Dolatkhani, Samaneh Akbarpour, Seyed Aria Nejadghaderi, Morvarid Najafi, Parmida Sadat Pezeshki, Akram Khalili Noushabadi, Hoomaan Ghasemi
BACKGROUND: Acute kidney injury is a complication of COVID-19 and is associated with severity. Despite no specific antiviral treatment strategy, lopinavir/ritonavir and remdesivir have been used. Data on the association between AKI and receiving antiviral agents with outcomes in hospitalized patients with COVID-19 is scarce. We aimed to determine the incidence of AKI and its outcomes in COVID-19 patients with and without antiviral medications. METHODS: We conducted a retrospective study on hospitalized adult patients with SARS-CoV-2 infection in a tertiary center...
2023: PloS One
#8
JOURNAL ARTICLE
Mohammad Ali Ghoflgar Ghasemi, Hamed Hamishehkar, Afshin Javadi, Aziz Homayouni-Rad, Hoda Jafarizadeh-Malmiri
Researchers have made significant discoveries in addressing the limitations of essential oils (EOs) in food packaging using encapsulation systems combined with nanoparticles (NPs). This study aimed to develop a unique coating for beef preservation using nanostructured lipid carriers (NLCs). The optimal formulation of NLCs was determined based on size, zeta potential, and loading rate, achieving a content of 71.4% savory EO. A composite coating containing NPs was then created using different concentrations of NLCs (0, 0...
September 24, 2023: Food Chemistry
#9
JOURNAL ARTICLE
Elham Khoshbin, Leila Ghasemi, Rooholah Behroozi, Zahra Khosravi, Afsaneh Rahmati, Loghman Rezaeisoufi, Hamed Karkehabadi
Objective: In endodontic treatments, performing appropriate anesthesia in patients with irreversible pulpitis in mandibular molars may result in pain and severe problems. The irradiation of low-level lasers could be effective in this regard due to its anti-inflammatory and regenerative properties. This study aimed to assess the effect of 810 nm diode laser on the time of initiation and depth of anesthesia for endodontic treatment of mandibular first molars with symptomatic irreversible pulpitis. Materials and methods: This randomized controlled clinical trial evaluated 60 patients requiring endodontic treatment of mandibular first molars with symptomatic irreversible pulpitis and pain score ≥114 according to the Heft-Parker visual analog scale (HP-VAS)...
September 2023: Photobiomodulation, photomedicine, and laser surgery
#10
JOURNAL ARTICLE
Minoo Mohraz, Katayoun Vahdat, Seyyed-Hadi Ghamari, Mohsen Abbasi-Kangevari, Erfan Ghasemi, Yasaman Ghabdian, Negar Rezaei, Maryam Amini Pouya, Asghar Abdoli, Mohammad-Reza Malekpour, Keyvan Koohgir, Sahar Saeedi Moghaddam, Payam Tabarsi, Mohsen Moghadami, Farzin Khorvash, Rozita Khodashahi, Mohammadreza Salehi, Hamed Hosseini
OBJECTIVE: To report the efficacy, safety, and exploratory immunogenicity findings of two 5 µg doses of the BIV1-CovIran vaccine. DESIGN: Randomised, placebo controlled, double blind, multicentre, phase 3 clinical trial. SETTING: In six cities of Iran, including Bushehr, Isfahan, Karaj, Mashhad, Shiraz, and Tehran. The first vaccine or placebo injection of the first participant was on 16 May 2021 in Tehran. The last vaccine or placebo injection of the last participant occurred on 15 July 2021 in Isfahan...
September 21, 2023: BMJ: British Medical Journal
#11
JOURNAL ARTICLE
Human biomonitoring and reference values of urinary 1-hydroxypyrene among Iranian adults population.
Zahra Soleimani, Rosa Haghshenas, Yousef Farzi, Masud Yunesian, Amirmohammad Khalaji, Amir Hossein Behnoush, Amir Karami, Mahia Mehrabi, Erfan Ghasemi, Fatemeh Ashkani, Kazem Naddafi, Abolghasem Djazayeri, Hamed Pouraram, Alireza Mesdaghinia, Farshad Farzadfar
Polycyclic aromatic hydrocarbons (PAHs) are one of the most important environmental pollutants. Urinary concentrations of 1-hydropyren metabolites of PAHs have been used as biomarkers of these chemicals' exposure in humans. This cross-sectional study was conducted on 468 healthy Iranian adults over 25 years old and non-smokers in six provinces who were selected based on the clustering method. Fasting urine sampling and body composition and demographic measurements were performed. Urine samples were analyzed by GC-MS...
September 8, 2023: Environmental Science and Pollution Research International
#12
JOURNAL ARTICLE
Hamid Gharaee, Mohammad-Reza Sedaghat, Javad Sadeghi, Hamed Tabesh, Ahmad Gharouni, Somayeh Ghasemi Moghadam, Vahide Nozari, Samira Beigi
BACKGROUND: Wound construction is a critical step in phacoemulsification. Using anterior segment optical coherence tomography (AS-OCT), we compared the morphological features and complications of main incisions made by junior or senior residents during phacoemulsification. METHODS: This cross-sectional comparative study included eyes with senile cataracts that underwent uneventful phacoemulsification with a clear corneal incision made by seven senior and eight junior ophthalmology residents...
2023: Medical Hypothesis, Discovery and Innovation in Ophthalmology
#13
REVIEW
Masoumeh Sadeghi, Ali Askari, Fatemeh Bostan, Afshin Heidari, Golsa Ghasemi, Ghazaal Alavi Tabatabaei, Hamed Rafiee, Raheleh Karimi, Hamidreza Roohafza
Considering the worldwide mortality and morbidity of cardiovascular diseases (CVDs), the necessity of using multiple pills due to the chronicity of this condition, and the importance of medication adherence in these patients, we conducted this systematic review and meta-analysis to assess the polypill effect on adherence in patients with established CVD and at high risk. To accomplish this review, we searched various databases to access grey literature and several electronic databases to find randomized controlled trials (RCTs) assessing polypills compared to individual pills from January 2000 to October 2022...
August 26, 2023: Current Problems in Cardiology
#14
JOURNAL ARTICLE
Elham Shakiba, Ali Bazi, Hamed Ghasemi, Reza Eshaghi Gorji, Seyyed Alireza Mehdipour, Banafsheh Nikfar, Mohsen Rashidi, Sepideh Mirzaei
Considering the unfavourable response of breast cancer (BC) to treatment, we assessed the therapeutic potential hesperidin in mice bearing 4T1 BC tumours. Anti-tumour effects were assessed by measuring pathologic complete response (pCR), survival analysis, immunohistochemistry for E-cadherin, VEGF, MMP9, MMP2 and Ki-67, serum measurement of IFNγ and IL-4, and gene expression analysis of CD105, VEGFa, VEGFR2 and COX2. Survival of tumour-bearing mice was the highest in mice receiving a combination of hesperidin and doxorubicin (Dox) (80%) compared to the normal saline (43%), hesperidin 5 (54%), 10 (55...
August 15, 2023: Journal of Cellular and Molecular Medicine
#15
JOURNAL ARTICLE
Nahid Ghanbarzadeh, Pouria Mohammadparast-Tabas, Hamed Aramjoo, Elahe Allahyari, Saeedeh Ghasemi, Soheila Erfani, Behzad Mesbahzadeh, Hamideh Dehghan, Majid Zare-Bidaki
BACKGROUND: Amniotic fluid in the uterus is beneficial for the fetus growth and protection due to its nutritional elements as well as its antibacterial and anti-inflammatory properties. Today, body membranes are increasingly being used in multiple fields. The purpose of the current study was evaluation of the antibacterial effects of amniotic fluid and comparison of its effects on pathogenic and probiotic bacteria. METHODS: This experimental study was conducted on amniotic fluid obtained from 43 healthy mothers who gave birth by selective cesarean section...
2023: Journal of Reproduction & Infertility
#16
REVIEW
Mohammad Soleimani, Zohreh Ebrahimi, Kosar Sadat Ebrahimi, Negin Farhadian, Mohsen Shahlaei, Kasra Cheraqpour, Hamed Ghasemi, Sajad Moradi, Arthur Y Chang, Sina Sharifi, Seyed Mahbod Baharnoori, Ali R Djalilian
Corneal diseases are among the most common causes of blindness worldwide. Regardless of the etiology, corneal opacity- or globe integrity-threatening conditions may necessitate corneal replacement procedures. Several procedure types are currently available to address these issues, based on the complexity and extent of injury. Corneal allograft or keratoplasty is considered to be first-line treatment in many cases. However, a significant proportion of the world's population are reported to have no access to this option due to limitations in donor preparation...
July 2023: Journal of International Medical Research
#17
REVIEW
Fakhradin Ghasemi, Amin Doosti-Irani, Hamed Aghaei
BACKGROUND: Job safety analysis (JSA) is a popular technique for hazard identification and risk assessment in workplaces that has been applied across a wide range of industries. This systematic review was conducted to answer four main questions regarding JSA: (1) which sectors and areas have used JSA? (2) What has been the aim of employing JSA? (3) What are the shortcomings of JSA? (4) What are the new advances in the field of JSA? METHODS: Three main international databases were searched: SCOPUS, Web of Science, and PubMed...
June 2023: Safety and Health At Work
#18
JOURNAL ARTICLE
Afshin Ostovar, Sadaf Sepanlou, Mohammad Shariati, Alireza Mahdavi Hezaveh, Elham Yousefi, Alieh Hodjatzadeh, Mehdi Afkar, Abbas Pariani, Alireza Moghisi, Kazem Khalagi, Mehdi Najmi, Shahnaz Bashti, Saeideh Aghamohammadi, Mohammad Bagherzade Yazdi, Azizollah Atefi, Ahmad Joneidi, Hamed Barakati, Ramin Heshmat, Niloofar Peykari, Mansour Ranjbar, Christoph Hammelman, Shanthi Mendis, Mehrdad Pariyanzeitooni, Nahid Mohammadi, Kourosh Noemani, Hojatollah Barati, Reza Alborzinia, Pari Mirshfiee, Naghmeh Khaligh, Mostafa Anvari, Ali Morsali, Amirhosein Shirzadian, Mahnaz Hasani, Maryam Zakeri, Kazem Alizadeh Barzian, Hamid Azadmehr, Ali Ghasemi, Afshin Delshad, Razieh Hajiuni, Mohammad Ali Shafieinia, Mostafa Dolatabad, Maryam Soltani, Abdollah Azizi, Mohsen Izadi, Hasan Rokhshad, Gholamreza Sadeghi, Mohammad-Hossein Rahmani, Seyed Mahdi Sedaghat, Hamide Sadeghzade, Raziyehsadat Mirmoieni, Ali Golmohammadi, Tayebeh Najafi Moghadam, Asad Ehsanzadeh, Abdolmohsen Parvin, Mahshid Ahmadian, Ramesh Hosseinkhani, Shapour Shadmand, Fateme Shahrokhi, Morteza Panje Shahi, Mehdi Shafiei Bafti, Sara Shahabadi, Soleiman Shaddel, Abbas Bayat Asghari, Esmaeel Talebi, Sajjad Sharafi, Maryam Kooshki, Faeghe Asadiyan, Mohammad-Jafar Sadeghi, Babak Eghbali, Gholamhosein Norouzinezhad, Solmaz Farrokhzad, Mahdi Mirheidari, Mohsen Nejadghaderi, Najme Iran Nezhad, Seyed Mohsen Mehri, Ardeshir Rahimzadeh, Hamid Etminanbakhsh, Azita Dalili, Haniah Aminforghani, Mohammad-Naser Rahbar, Sepinood Rostampour, Mansoureh Fateh, Fariba Moradi, Seyed Ali Mousavi, Gholamreza Pourabazari, Jabraeil Sharbafi, Alireza Aminmanesh, Azita Karimi, Mohammadreza Sarbazi, Farzaneh Farbakhsh, Javad Alinezhad, Tahereh Parishan Kordiani, Nourieh Dalili, Zafar Parisay, Mohammad Reza Sadeghian, Amir Bazishad, Majid Sartipi, Ali Seydi, Alireza Raeisi
PURPOSE: Hypertension is one of the most important risk factors for premature mortality and morbidity in Iran. The objective of the Iranian blood pressure (BP) measurement campaign was to identify individuals with raised blood pressure and providing appropriate care and increase the awareness among the public and policymakers of the importance of tackling hypertension. METHODS: The campaign was conducted in two phases. The first (communication) phase started on May 17th (International Hypertension Day)...
June 2023: Journal of Diabetes and Metabolic Disorders
#19
Mahboubeh Bayat, Tahereh Kashkalani, Mahmoud Khodadost, Azad Shokri, Hamed Fattahi, Faeze Ghasemi Seproo, Fatemeh Younesi, Roghayeh Khalilnezhad
OBJECTIVES: The health system reform process is highly political and controversial, and in most cases, it fails to realize its intended goals. This study was conducted to synthesize factors underlying the failure of health system reforms. METHODS: In this systematic review and meta-synthesis, we searched 9 international and regional databases to identify qualitative and mixed-methods studies published up to December 2019. Using thematic synthesis, we analyzed the data...
March 2023: Journal of Preventive Medicine and Public Health
#20
JOURNAL ARTICLE
Hamed Zare, Tahereh Farkhondeh, Hamid Bakherad, Hengame Sharifi, Maryam Hosseinzade Shirzeyli, Saeed Samarghandian, Fahimeh Ghasemi
The coronavirus disease 2019 (Covid-19) pandemic has been considered a major threat to human health. Effective therapeutic approaches are urgently required. Spike protein and the Angiotensin-converting enzyme 2 (ACE2) receptors have critical roles in SARS-CoV-2 infection. As a result, these two proteins are considered potential targets for the development of a wide variety of biotherapeutics and vaccines for controlling Covid-19. The fusion proteins have desirable medicinal properties, including high serum half-life, stability, and solubility in the body...
April 10, 2023: Current Molecular Medicine
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