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Reza Ghaffari

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https://www.readbyqxmd.com/read/29154069/nigella-sativa-improves-glucose-homeostasis-and-serum-lipids-in-type-2-diabetes-a-systematic-review-and-meta-analysis
#1
REVIEW
Reza Daryabeygi-Khotbehsara, Mahdieh Golzarand, Mohammad Payam Ghaffari, Kurosh Djafarian
BACKGROUND & OBJECTIVE(S): Global prevalence of type 2 diabetes (T2D) is very high and is currently growing alarmingly. With respect to recent researchers' attention to the potential role of herbal medicine in disease prevention and management, the present meta-analysis review investigates the effectiveness of Nigella sativa (N. sativa), a popular herb, in T2D. METHODS: Literature search was conducted covering PubMed/Medline, Scopus, and Cochrane Registry of Clinical Trials up to February 2017 to obtain the relevant published intervention studies...
December 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29128812/pharmacological-evidence-for-the-involvement-of-adenosine-triphosphate-sensitive-potassium-channels-in-chloroquine-induced-itch-in-mice
#2
Sattar Ostadhadi, Arash Foroutan, Nazgol-Sadat Haddadi, Abbas Norouzi-Javidan, Majid Momeny, Ghazaleh Zarrinrad, Seyed Hamid Ghaffari, Ahmad-Reza Dehpour
BACKGROUND: Chloroquine (CQ) evokes itch in human and scratching behavior in rodents through a histamine-independent pathway. Chloroquine directly excites peripheral sensory neurons which convey itch signals to the central nervous system. It has been revealed that ATP-sensitive potassium channels (KATP channels) are important in regulating neuronal excitability. Thus, we aimed to investigate the involvement of KATP channels in CQ-induced itch which may also reveal a linkage between metabolic state of cells and itch...
June 3, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29076562/a-systematic-review-of-empirical-studies-on-methodology-and-burden-of-informal-patient-payments-in-health-systems
#3
REVIEW
Abdolvahed Khodamoradi, Mohammad Payam Ghaffari, Reza Daryabeygi-Khotbehsara, Haniye Sadat Sajadi, Reza Majdzadeh
INTRODUCTION: Informal patients' payments (IPPs) is a sensitive subject. The aim of current study was to assess the trends in informal payment studies and explore methods of IPPs measurement, prevalence, and features (payment type, volume, and receiver) in various contexts. METHODS: A search strategy was developed to identify peer-reviewed articles addressing informal payments on PubMed, Science Direct, Web of Science, Scopus, and CINAHL. A total of 1252 studies were identified initially...
October 27, 2017: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/29017374/prevalence-of-sexually-transmitted-infections-and-their-risk-factors-among-female-sex-workers-in-isfahan-iran-a-cross-sectional-study
#4
Maryam Nasirian, Sina Kianersi, Shervin Ghaffari Hoseini, Nazila Kassaian, Majid Yaran, Parisa Shoaei, Behrooz Ataei, Reza Fadaei, Marjan Meshkati, Alireza Emami Naeini, Mojtaba Rostami Jalilian
OBJECTIVES: Female sex workers (FSWs) are at high risk of sexually transmitted infections (STIs) and form a core group to facilitate STI spreading. We aimed to estimate the prevalence of STIs among FSWs who attended Female Harm Reduction Center of Isfahan, Iran, and to determine the association between risky behaviors and STIs. STUDY DESIGN: In a cross-sectional study, 99 FSWs were recruited and interviewed about demographic characteristics and risky behaviors. A trained midwife examined FSWs for genital ulcer, abnormal vaginal discharge, and cervicitis...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28986276/expression-and-localization-of-relaxin-family-peptide-receptor-4-in-human-spermatozoa-and-impact-of-insulin-like-peptide-5-on-sperm-functions
#5
Imaneh Shamayeli Yeganeh, Amir Hossein Taromchi, Fatemeh Fadaei Fathabadi, Reza Nejatbakhsh, Marefat Ghaffari Novin, Saeed Shokri
Insulin-like peptide 5 (INSL5) is a member of the insulin superfamily peptide that interacts with the relaxin family peptide receptor 4 (RXFP4). Numerous recent studies have focused on the functional effects of INSL5 on fat and glucose metabolism. Although there is no evidence that the human sperm may be a candidate target of INSL5, it has been detected in mice testis and sperm. Therefore, the present study sought to analyze the localization and expression of RXFP4 on human sperm and determine the efficiency of INSL5 in human sperm...
October 4, 2017: Reproductive Biology
https://www.readbyqxmd.com/read/28980195/air-pollution-and-admissions-due-to-st-elevation-myocardial-infarction-a-time-series-study-from-northwest-of-iran
#6
Samad Ghaffari, Reza Hajizadeh, Leili Pourafkari, Behrouz Shokouhi, Arezou Tajlil, Sarvin Mazani, Hadiseh Kavandi, Hosein Ansari, Nader D Nader
We investigated the association between the levels of air pollutants and the number of daily admissions due to ST segment elevation myocardial infarction (STEMI) in a metropolitan in the northwest of Iran. Daily concentrations of common air pollutants were obtained for the greater city of Tabriz for a period of 2 years. These reports included sulfur dioxide (SO2), nitrogen dioxide (NO2), nitric oxide (NO), nitrogen byproducts (NOx), carbon monoxide (CO), ozone (O3), and particulate matters < 10 μm (PM10)...
October 4, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28975536/asthma-disease-as-cause-of-admission-to-hospitals-due-to-exposure-to-ambient-oxidants-in-mashhad-iran
#7
Hamid Reza Ghaffari, Hamideh Ebrahimi Aval, Ahmad Alahabadi, Adel Mokammel, Ramzanali Khamirchi, Samira Yousefzadeh, Ehsan Ahmadi, Abolfazl Rahmani-Sani, Mehdi Estaji, Amin Ghanbarnejad, Abdolmajid Gholizadeh, Mahmoud Taghavi, Mohammad Miri
Nowadays, asthma is one of the most common chronic respiratory diseases, worldwide. Many reports have emphasized the correlation between the short-term exposure to the ambient air pollutants and acute respiratory diseases, especially among children with asthmatic symptoms. The aim of this study was to evaluate the relationship between the exposure to three atmospheric antioxidants (NO2, SO2, and O3) and hospital admission due to asthmatic disease (HAAD) in the city of Mashhad, Iran. The concentrations of atmospheric antioxidants were obtained from the real-time monitoring stations located in the city...
October 4, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28954206/phospholipase-c-zeta-parameters-in-sperm-from-polymorphic-teratozoospermic-men
#8
Nahid Azad, Hamid Nazarian, Marefat Ghaffari Novin, Reza Masteri Farahani, Abbas Piryaei, Mohammad Hassan Heidari
Teratozoospermia is a disorder associated with high abnormal sperm morphology which affects fertility in males. In recent years, it has been described that biomarker-based sperm quality evaluation can alleviate male infertility treatment. Phospholipase C zeta (PLCζ) is a sperm-specific factor which appears to be a predicting biomarker for fertilization potential of males. Following fertilization, PLCζ enters into oocyte cytoplasm and induces oocyte activation, a fundamental stage in initiation of embryo development...
September 24, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/28954204/oligoasthenoteratozoospermic-oat-men-display-altered-phospholipase-c-%C3%AE-plc%C3%AE-localization-and-a-lower-percentage-of-sperm-cells-expressing-plc%C3%AE-and-post-acrosomal-sheath-ww-domain-binding-protein-pawp
#9
Nahid Azad, Hamid Nazarian, Marefat Ghaffari Novin, Reza Masteri Farahani, Abbas Piryaei, Mohammad Hassan Heidari, Meghdad Abdollahpour Alitappeh
Oligoasthenoteratozoospermia (OAT) is demonstrated to be one of the most common causes of male subfertility. Phospholipase C ζ (PLCζ), a sperm-specific protein, is considered to be one of the sperm-borne oocyte activating factors (SOAFs), which play a vital role in fertilization. The post-acrosomal sheath WW domain-binding protein (PAWP) is another candidate for SOAF. The aim of this study was to compare the PLCζ localization patterns and percentage of PLCζ- and PAWP-positive sperm cells in patients with OAT and fertile men with normozoospermia...
September 27, 2017: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28916186/clinical-immunological-and-genetic-spectrum-of-696-patients-with-combined-immunode%C3%AF-ciency
#10
Hassan Abolhassani, Janet Chou, Wayne Bainter, Craig Platt, Mahmood Tavassoli, Toba Momen, Marzieh Tavakol, Mohammad Hossein Eslamian, Mohammad Gharagozlou, Masoud Movahedi, Mohsen Ghadami, Amir Ali Hamidieh, Gholamreza Azizi, Reza Yazdani, Mohsen Afarideh, Alireza Ghajar, Arash Havaei, Zahra Chavoushzadeh, Seyed Alireza Mahdaviani, Taher Cheraghi, Nasrin Behniafard, Reza Amin, Soheila Aleyasin, Reza Faridhosseini, Farahzad Jabbari-Azad, Mohammamd Nabavi, Mohammad Hassan Bemanian, Saba Arshi, Rasol Molatefi, Roya Sherkat, Mahboubeh Mansouri, Mehrnaz Mesdaghi, Delara Babaie, Iraj Mohammadzadeh, Javad Ghaffari, Alireza Shafiei, Najmeddin Kalantari, Hamid Ahanchian, Maryam Khoshkhui, Habib Soheili, Abbas Dabbaghzadeh, Afshin Shirkani, Rasoul Nasiri Kalmarzi, Seyed Hamidreza Mortazavi, Javad Tafaroji, Abbas Khalili, Javad Mohammadi, Babak Negahdari, Mohammad-Taghi Joghataei, Basel K Al-Ramadi, Capucine Picard, Nima Parvaneh, Nima Rezaei, Talal Chatila, Michel J Massaad, Sevgi Keles, Lennart Hammarström, Raif S Geha, Asghar Aghamohammadi
BACKGROUND: Combined immunodeficiencies (CIDs) are diseases of defective adaptive immunity with diverse clinical phenotypes. Although CIDs are more prevalent in the Middle East than Western countries, the resources for genetic diagnosis are limited. OBJECTIVES: This study aims to characterize the categories of CID patients in Iran clinically and genetically. METHODS: Clinical and laboratory data were obtained from 696 patients with CIDs. Patients were subdivided into those with syndromic (344 patients) and non-syndromic CIDs (352 patients)...
September 12, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28865408/peptide-based-vaccines-derived-from-fc%C3%AE%C2%B5ri-beta-subunit-can-reduce-allergic-response-in-mice-model
#11
Ahad Zare, Ali Akbar Pourfathollah, Zahra Pourpak, Janos Szebeni, Seyed Mohammad Reza Ghaffari, Gholam Ali Kardar
Current therapeutic approaches in allergic diseases especially asthma generally focus on using immunological strategies. According to the importance of FceRI in controlling allergic response we used two extracellular regions of Fc epsilon receptor I (FceRI) beta subunit peptides to design two peptide-based vaccines. Probably these peptides vaccines by triggering the immune response to FceRI can reduce the allergic symptoms through blocking the IgE specific receptor. Two extracellular parts of FceRI beta subunit were made by peptide synthesizer and conjugated with keyhole limpet Hemocyanin...
August 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/28817391/tacrolimus-eye-drops-as-adjunct-therapy-in-severe-corneal-endothelial-rejection-refractory-to-corticosteroids
#12
Reza Ghaffari, Hamed Ghassemi, Mehran Zarei-Ghanavati, Golshan Latifi, Shima Dehghani, Zeeshan Haq, Ali R Djalilian
PURPOSE: To evaluate the safety and efficacy of tacrolimus eye drops as adjunctive therapy in the treatment of severe corneal endothelial rejection after penetrating keratoplasty refractory to corticosteroids. METHODS: In this prospective interventional case series, 11 eyes of 11 patients assessed for severe corneal endothelial rejection, with an inadequate response to topical, local, and systemic corticosteroids, were treated with either 0.01% or 0.05% tacrolimus eye drops 4 times daily...
October 2017: Cornea
https://www.readbyqxmd.com/read/28672766/the-value-of-peripheral-blood-eosinophil-count-in-predicting-in-stent-restenosis-in-patients-with-stable-angina-pectoris-undergoing-drug-eluting-stenting
#13
Reza Hajizadeh, Samad Ghaffari, Ahmad Separham, Behrouz Shokouhi, Hadiseh Kavandi, Leili Pourafkari, Nader D Nader
INTRODUCTION: In-stent restenosis (ISR) remains a major limitation of percutaneous coronary intervention (PCI). A role for peripheral blood cells as major regulators of immune and inflammatory systems has been proposed. We aim to evaluate the relationship between eosinophil count and development of restenosis after drug-eluting stent (DES) implantation. METHODS: In this prospective study, all consecutive patients undergoing elective DES implantation for chronic stable angina (CSA) in a university-affiliated heart center within a 6-month period were enrolled and followed for another 6 months...
December 1, 2017: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28646172/dacomitinib-a-pan-inhibitor-of-erbb-receptors-suppresses-growth-and-invasive-capacity-of-chemoresistant-ovarian-carcinoma-cells
#14
Majid Momeny, Ghazaleh Zarrinrad, Farima Moghaddaskho, Arash Poursheikhani, Ghazaleh Sankanian, Azam Zaghal, Shahab Mirshahvaladi, Fatemeh Esmaeili, Haniyeh Eyvani, Farinaz Barghi, Zahra Sabourinejad, Zivar Alishahi, Hassan Yousefi, Reza Ghasemi, Leila Dardaei, Davood Bashash, Bahram Chahardouli, Ahmad R Dehpour, Javad Tavakkoly-Bazzaz, Kamran Alimoghaddam, Ardeshir Ghavamzadeh, Seyed H Ghaffari
Epithelial ovarian cancer (EOC) is the most lethal gynaecological malignancy worldwide. Development of chemoresistance and peritoneal dissemination of EOC cells are the major reasons for low survival rate. Targeting signal transduction pathways which promote therapy resistance and metastatic dissemination is the key to successful treatment. Members of the ErbB family of receptors are over-expressed in EOC and play key roles in chemoresistance and invasiveness. Despite this, single-targeted ErbB inhibitors have demonstrated limited activity in chemoresistant EOC...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28629042/functionalization-of-zno-nanoparticles-by-3-mercaptopropionic-acid-for-aqueous-curcumin-delivery-synthesis-characterization-and-anticancer-assessment
#15
Seyed-Behnam Ghaffari, Mohammad-Hossein Sarrafzadeh, Zahra Fakhroueian, Shadab Shahriari, M Reza Khorramizadeh
Inherent biocompatibility and stability of zinc oxide nanoparticles (ZnO-NPs) and their biomedical potentials make them an emerging candidate for drug delivery. The aim of this study was to develop and assess a simple procedure for surface functionalization of ZnO-NPs by 3-mercaptopropionic acid (MPA) for water-soluble curcumin delivery. Carboxyl-terminated ZnO nanoparticles were successfully made using ZnCl2 and NaOH in the presence of MPA. The functional groups were activated by 1,1'-carbonyldiimidazole (CDI) and the curcumin bonding was carried out at room temperature for 24h...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28621246/association-between-admission-neutrophil-to-lymphocyte-ratio-and-outcomes-in-patients-with-acute-exacerbation-of-chronic-obstructive-pulmonary-disease
#16
Shaghayegh Rahimirad, Mohammad Reza Ghaffary, Mohammad Hossein Rahimirad, Farid Rashidi
Introduction: The prognostic significance of neutrophil-to-lymphocyte ratio (NLR), derived-neutrophil-to-lymphocyte ratio (d-NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) have been shown in many diseases. To the best of our knowledge, there is no published report evaluation of those parameters in acute exacerbation of chronic obstructive pulmonary disease (AECOPD). The aims of this study are to evaluate the parameters in predicting in-hospital mortality in patients with AECOPD...
March 2017: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/28580013/a-comparative-study-of-anaerobic-fixed-film-baffled-reactor-and-up-flow-anaerobic-fixed-film-fixed-bed-reactor-for-biological-removal-of-diethyl-phthalate-from-wastewater-a-performance-kinetic-biogas-and-metabolic-pathway-study
#17
Samira Yousefzadeh, Ehsan Ahmadi, Mitra Gholami, Hamid Reza Ghaffari, Ali Azari, Mohsen Ansari, Mohammad Miri, Kiomars Sharafi, Soheila Rezaei
BACKGROUND: Phthalic acid esters, including diethyl phthalate (DEP), which are considered as top-priority and hazardous pollutants, have received significant attention over the last decades. It is vital for industries to select the best treatment technology, especially when the DEP concentration in wastewater is high. Meanwhile, anaerobic biofilm-based reactors are considered as a promising option. Therefore, in the present study, for the biological removal of DEP from synthetic wastewater, two different anaerobic biofilm-based reactors, including anaerobic fixed film baffled reactor (AnFFBR) and up-flow anaerobic fixed film fixed bed reactor (UAnFFFBR), were compared from kinetic and performance standpoints...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28461864/the-effectiveness-of-ibuprofen-and-lorazepam-combination-therapy-in-treating-the-symptoms-of-acute-migraine-a-randomized-clinical-trial
#18
Reza Ebrahimi Rad, Fatemeh Ghaffari, Zahra Fotokian, Azadeh Ramezani
BACKGROUND: Migraine is a common, episodic and debilitating disease. The migraineur not only suffers from pain, but also lives with a diminished to poor quality of life. Several medicinal therapies are used to abate the debilitating symptoms of this disease. OBJECTIVE: The present study was conducted to determine the effectiveness of Ibuprofen and Lorazepam combination therapy in treating the symptoms of acute migraine. METHODS: The present randomized clinical trial study used the pretest-posttest design with three comparison treatments, to examine 90 patients with an average of two to six attacks per month and an initial diagnosis of migraine based on the International Headache Society (HIS) criteria...
March 2017: Electronic Physician
https://www.readbyqxmd.com/read/28449991/evaluation-of-abamectin-diazinon-and-chlorpyrifos-pesticide-residues-in-apple-product-of-mahabad-region-gardens-iran-in-2014
#19
Meghdad Pirsaheb, Nazir Fattahi, Rahim Rahimi, Kiomars Sharafi, Hamid Reza Ghaffari
The purpose of this study was to investigate abamectin, diazinon and chlorpyrifos in apple from the Mahabad of Iran. The influences of several parameters including shadow and sun, geographical directions and varieties of apples, whether they are golden or red type, was also taken into account on the residuals of the pesticides in the samples. The results indicated that sun considerably decreased the concentrations of diazinon and chlorpyrifos in samples exposed to it. Geographical directions are showed to be non-influential on diazinon while they are influential on chlorpyrifos ones...
September 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28435821/utilization-of-pfge-as-a-powerful-discriminative-tool-for-the-investigation-of-genetic-diversity-among-mrsa-strains
#20
Solmaz Ohadian Moghadam, Mohammad Reza Pourmand, Masoumeh Douraghi, Samira Sabzi, Parisa Ghaffari
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is a significant challenge to the burn patient. The implementation of proper monitoring programs and prompt identification of epidemic MRSA strains are critical to consequently control and eradicate potential outbreaks. This study aimed to define the genetic relatedness of MRSA strains isolated from burn patients by analyzing the large fragments of DNA. METHODS: In this cross-sectional study, 126 pus/wound swabs from skin and soft tissue infections (SSTIs) were collected from inpatients of Shahid Motahari Burn Center (Tehran, Iran) in 2013...
March 2017: Iranian Journal of Public Health
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