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Reza Ghaffari

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https://www.readbyqxmd.com/read/27878128/the-epidemilogical-characteristics-of-motorcyclists-associated-injuries-in-road-traffics-accidents-a-hospital-based-study
#1
Saber Ghaffari-Fam, Ehsan Sarbazi, Amin Daemi, Mohammad Reza Sarbazi, Hossein Ali Nikbakht, Shaker Salarilak
OBJECTIVES: To determine the epidemiology of injuries of the motorcyclists in road traffic accidents (RTIs) between 2008 and 2014 in East Azarbayejan province of Iran. METHODS: A cross-sectional study was performed in East Azerbaijan province in Imam Reza hospital on motorcyclists subjected to injuries in RTIs between 2008 and 2014. Demographic characteristics (age, sex), duration of hospitalization, final status of injured people after discharge from the hospital, admission ward, number of admissions due to injuries in RTIs, nature of injury, and the clinical services provided to injured people were gathered from hospital information system (HIS)...
October 2016: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/27777696/effect-of-remote-ischemic-post-conditioning-on-oxidative-stress-in-blood-of-stemi-patients-treated-with-primary-angioplasty
#2
Hassanali Lotfollahi, Mustafa Mohammadi, Samad Ghaffari, Reza Badalzadeh, Bahram Sohrabi, Naser Aslanabadi, Ahmad Separham, Ali Golmohammadi, Ali Abbasnejad, Mehri Roshani
Introduction: This study designed to use remote ischemic post conditioning (RIPC) as a protective strategy during percutaneous coronary intervention (PCI) in patients with ST segment elevation myocardial infarction (STEMI) to reduce myocardial cells damage due to reperfusion injury. Methods: Sixty-one patients were divided into test group (32 patients) receiving RIPC and control group (29 patients). Patients were included with first MI who had 20-80 years old. The RIPC protocol was applied on patients arm in three successive episodes during the opening of infarct-related artery (IRA)...
2016: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/27760066/the-impact-of-allopurinol-on-patients-with-acute-st-elevation-myocardial-infarction-undergoing-thrombolytic-therapy
#3
Ahmad Separham, Samad Ghaffari, Hossein Najafi, Reza Ghaffari, Mojtaba Ziaee, Hossein Babaei
Allopurinol may have protective effects over ischemic reperfusion injury and reduce infarct size. In this randomized study, we aimed to evaluate the impact of allopurinol in patients with acute ST elevation myocardial infarction (STEMI) undergoing thrombolytic therapy. Overall, 140 patients with STEMI were randomly assigned to receive 400 mg of allopurinol or placebo before treating with streptokinase. Then, study group received 100 mg of allopurinol daily for 28 days and placebo group received placebo for the same period...
October 2016: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/27699605/femtosecond-laser-assisted-lasik-versus-prk-for-high-myopia-comparison-of-18-month-visual-acuity-and-quality
#4
Hassan Hashemi, Reza Ghaffari, Mohammad Miraftab, Soheila Asgari
PURPOSE: To compare 18-month outcomes between femtosecond laser-assisted LASIK (femto-LASIK) and photorefractive keratectomy with mitomycin-C (PRK-MMC) for myopia of more than 7.0 D in terms of visual acuity and quality. METHODS: In this comparative nonrandomized clinical trial, 60 eyes from 30 patients (30 eyes in each group) were enrolled. The two procedures were compared in terms of 18-month changes in uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction spherical equivalent, ocular and corneal higher order aberrations (HOAs), and contrast sensitivity (CS)...
October 3, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27688908/corneal-biomechanical-findings-in-contact-lens-induced-corneal-warpage
#5
Fateme Alipour, Mojgan Letafatnejad, Amir Hooshang Beheshtnejad, Seyed-Farzad Mohammadi, Seyed Reza Ghaffary, Narges Hassanpoor, Mehdi Yaseri
Purpose. To evaluate the difference in biomechanical properties between contact lens induced corneal warpage and normal and keratoconic eyes. Method. Prospective observational case control study, where 94 eyes of 47 warpage suspicious and 46 eyes of 23 keratoconic patients were included. Warpage suspected cases were followed until a definite diagnosis was made (warpage, normal, or keratoconus). Results. 44 eyes of 22 patients had contact lens related corneal warpage. 46 eyes of 23 people were diagnosed as nonwarpage normal eyes...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27589149/investigation-of-outdoor-btex-concentration-variations-sources-spatial-distribution-and-risk-assessment
#6
Mohammad Miri, Maryam Rostami Aghdam Shendi, Hamid Reza Ghaffari, Hamideh Ebrahimi Aval, Ehsan Ahmadi, Ebrahim Taban, Abdolmajid Gholizadeh, Mohsen Yazdani Aval, Amir Mohammadi, Ali Azari
The aim of this study was to measure BTEX (benzene, toluene, ethylbenzene, and xylenes) concentrations in the ambient air of Tehran, the capital of Iran, and investigate their seasonal variations, probable sources, spatial mapping, and risk assessment. The concentrations of BTEX were measured using a continuous monitoring device installed in seven stations around the city. Spatial mapping procedure was conducted using the inverse distance weighting (IDW) method. Monte Carlo simulation was used to assess the carcinogenic and noncarcinogenic risks imposed by BTEX...
November 2016: Chemosphere
https://www.readbyqxmd.com/read/27496622/cutaneous-leishmaniasis-prevalence-and-morbidity-based-on-environmental-factors-in-ilam-iran-spatial-analysis-and-land-use-regression-models
#7
Mehdi Mokhtari, Mohammad Miri, Ali Nikoonahad, Ali Jalilian, Razi Naserifar, Hamid Reza Ghaffari, Farogh Kazembeigi
The aim of this study was to investigate the impact of the environmental factors on cutaneous leishmaniasis (CL) prevalence and morbidity in Ilam province, western Iran, as a known endemic area for this disease. Accurate locations of 3237 CL patients diagnosed from 2013 to 2015, their demographic information, and data of 17 potentially predictive environmental variables (PPEVs) were prepared to be used in Geographic Information System (GIS) and Land-Use Regression (LUR) analysis. The prevalence, risk, and predictive risk maps were provided using Inverse Distance Weighting (IDW) model in GIS software...
November 2016: Acta Tropica
https://www.readbyqxmd.com/read/27489597/association-of-serum-uric-acid-level-with-mortality-and-morbidity-of-patients-with-acute-st-elevation-myocardial-infarction
#8
Reza Hajizadeh, Samad Ghaffari, Rezvanieh Salehi, Sarvin Mazani, Sharmin Aghavali
INTRODUCTION: Investigating the clinical impact of serum uric acid (UA) and its lowering agents on the complications and mortality of acute ST-elevation myocardial infarction (STEMI) can open a new era in STEMI treatment. The aim of this study was to evaluate the effect of on admission serum UA level on the mortality and morbidity of patients admitted with STEMI. METHODS: A number of 608 patients with STEMI were enrolled in this study from December 21, 2012 until February 19, 2014...
2016: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/27452938/chest-tube-insertion-in-the-delayed-esophageal-perforation-phenomenon-a-tragic-or-beneficial-outcome
#9
Mohsen Sokouti, Mohammad Reza Ghaffari, Masoud Sokouti, Mohammad-Hossein Rahimi-Rad
A 53-year-old woman with foreign body esophageal perforation, was first misdiagnosed as pulmonary thromboembolism. In referral hospital her chest computed tomography was reported as giant hiatal hernia or giant pulmonary abscess. She was treated for abscess, after several days, right hemithorax tube thoracostomy was performed. After that, she developed necrotizing fasciitis on the chest wall. After a 19-day delay, we found a 5-cm mid-thoracic esophageal tearing during thoracotomy and repaired it. After 2 years follow up the patient condition is good...
May 2016: Chirurgia
https://www.readbyqxmd.com/read/27439925/association-of-abo-blood-group-with-incidence-and-outcome-of-acute-pulmonary-embolism
#10
Reza Hajizadeh, Hadiseh Kavandi, Mehdi Nadiri, Samad Ghaffari
OBJECTIVE: Association of ABO blood type with occurrence of pulmonary embolism (PE) has been demonstrated, and association of blood type with disease mortality and morbidity has recently been reported. Presently described was a retrospective study of mortality and morbidity according to blood group. METHODS: Blood type and medical data of 230 patients with confirmed PE was abstracted from medical records. Two control groups were used for data analysis; the 1st included blood donors (Control 1), the 2nd included hospital staff born in the same region (Control 2)...
July 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/27372966/birc5-genomic-copy-number-variation-in-early-onset-breast-cancer
#11
Kimia Ghaffari, Mehrdad Hashemi, Elmira Ebrahimi, Reza Shirkoohi
BACKGROUND: Baculoviral inhibitor of apoptosis repeat-containing 5 (BIRC5) gene is an inhibitor of apoptosis that expresses in human embryonic tissues but it is absent in most healthy adult tissues. The copy number of BIRC5 has been indicated to be highly increased in tumor tissues; however, its association with the age of onset in breast cancer is not well understood. METHODS: Forty tumor tissues of breast cancer were obtained from Tumor Bank of Cancer Institute, Imam Khomeini Hospital, Tehran, Iran...
September 2016: Iranian Biomedical Journal
https://www.readbyqxmd.com/read/27356685/melanoma-in-iran-a-retrospective-10-year-study
#12
Samira Ferdosi, Mojtaba Saffari, Sharareh Eskandarieh, Raziyeh Raziyeh, Mahsa Ghaffari Moghaddam, Alireza Ghanadan, Reza Shirkoohi
BACKGROUND: Melanoma, the most life-threatening type of skin cancer, is a malignant tumor initiating in melanocytes that rapidly metastasizes and causes death. MATERIALS AND METHODS: In this retrospective study, samples were selected from patients' information files in our Cancer Institute in Tehran with a designed checklist. A total of 322 files were found from 2003 until 2012. Then the raw data were transferred to Statistical Package for Social Sciences (SPSS) software version 16 and additional analysis was performed by Students t-test...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27277758/relationship-between-fas-and-fas-ligand-gene-polymorphisms-and-pre-eclampsia
#13
Elham Masoumi, Jalil Tavakkol-Afshari, Amin Reza Nikpoor, Haniyeh Ghaffari-Nazari, Sahar Tahaghoghi-Hajghorbani, Seyed Amir Jalali
AIM: In normal pregnancy, the Th1 subtype, responsible for the production of inflammatory cytokines, is reduced, and the Th2 subtype is increased to prohibit inflammation. In pre-eclampsia, the Th1 cell population is increased; thus, subsequent inflammation and trophoblast destruction occur. Polymorphisms in the Fas and Fas Ligand (FasL) promoter regions can influence Fas and FasL expression and accused to increase of Th1 subtype. METHODS: DNA samples from 153 pregnant women with pre-eclampsia and 140 controls were genotyped through polymerase chain reaction-restriction fragment length polymorphism...
June 9, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27274516/unintentional-home-injury-prevention-in-preschool-children-a-study-of-contributing-factors
#14
Somaye Younesian, Soad Mahfoozpour, Ensieh Ghaffari Shad, Hamid Kariman, Hamid Reza Hatamabadi
INTRODUCTION: Different factors such as parents' knowledge and attitudes regarding preventive measures (PM) have a great role in reducing children unintentional home injuries. The present study aims to evaluate the contributing factors of unintentional home injury prevention in preschool victims presented to the emergency department. METHODS: The subjects consisted of all the mothers of preschool children who were presented to the emergency department of Imam Hossein and Shohadaie-Hafte-Tir Hospitals, with unintentional home injuries, from March 2011 to February 2012...
2016: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/27252806/jak2v617f-allele-burden-measurement-in-peripheral-blood-of-iranian-patients-with-myeloproliferative-neoplasms-and-effect-of-hydroxyurea-on-jak2v617f-allele-burden
#15
Shirin Ferdowsi, Seyed H Ghaffari, Naser Amirizadeh, Azita Azarkeivan, Kamran Atarodi, Mohammad Faranoush, Gholamreza Toogeh, Reza Shirkoohi, Mohammad Vaezi, Mahtab Maghsoodlu, Kamran Alimoghaddam, Ardeshir Ghavamzadeh, Hosein Teimori Naghadeh
BACKGROUND: Myeloproliferative neoplasms (MPNs) are clonal malignant diseases that represent a group of conditions including polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF). The aim of this study was to evaluate possible correlations between JAK2V617F allele burden and clinicohematologic characteristics in Iranian patients with MPNs. We also aimed at determining the correlation between JAK2V617F allele burden and use of cyto reductive treatment (hydroxyurea)...
April 1, 2016: International Journal of Hematology-oncology and Stem Cell Research
https://www.readbyqxmd.com/read/27243355/evaluation-of-corneal-biomechanics-after-excimer-laser-corneal-refractive-surgery-in-high-myopic-patients-using-dynamic-scheimpflug-technology
#16
Hassan Hashemi, Soheila Asgari, Mahdi Mortazavi, Reza Ghaffari
OBJECTIVE: To compare the effect of femtosecond-assisted thin flap laser-assisted in situ keratomileusis (FS-LASIK) and photorefractive keratectomy with mitomycin-C (PRK-MMC) in highly myopic patients (>7.0 D [D]) on corneal biomechanical parameters. METHODS: In this prospective comparative interventional case series, 60 patients (30 patients in each group) with a manifest refractive spherical equivalent (MRSE) greater than 7.0 D were enrolled. Corvis ST parameters were measured before and at 3 and 6 months postoperatively...
May 26, 2016: Eye & Contact Lens
https://www.readbyqxmd.com/read/27220780/predictive-value-of-exercise-stress-test-induced-st-segment-changes-in-leads-v1-and-avr-in-determining-angiographic-coronary-involvement
#17
Samad Ghaffari, Reza Asadzadeh, Arezou Tajlil, Amirhossein Mohammadalian, Leili Pourafkari
BACKGROUND: The significance of electrocardiographic changes during exercise tolerance testing for distinguishing occluded artery is not well known. We tried to determine the role of ST elevation in leads aVR and V1 during exercise in detecting stenosis of left main coronary artery and proximal left anterior descending artery. METHODS: ST segment changes during exercise in 230 patients, who underwent diagnostic angiography, were documented. The association of ST elevation in lead aVR, V1 , leads aVR + V1 , and STE in leads aVR + V1 with ST depression in other leads with pattern of coronary stenosis were investigated...
May 25, 2016: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/27162912/epidemiological-and-clinical-characteristics-of-fall-injuries-in-east-azerbaijan-iran-a-cross-sectional-study
#18
Saber Ghaffari-Fam, Ehsan Sarbazi, Amin Daemi, Mohamadreza Sarbazi, Lachin Riyazi, Homayoun Sadeghi-Bazargani, Ali Allahyari
OBJECTIVE: To describe the epidemiological and clinical characteristics of fall injuries in East Azerbaijan, Iran. METHODS: This cross-sectional study was based on Hospital Information System (HIS) data for patients referred to the Imam Reza Hospital between 2008 and 2013. We recorded the demographic characteristics and epidemiological patterns of patients who were admitted to our center due to fall injuries. To standardize the reports the International Classification of Diseases (ICD), the International Classification of Diseases 9 Clinical Modification (ICD-9-CM) was used...
July 2015: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/27110521/experiences-of-infertile-women-seeking-assisted-pregnancy-in-iran-a-qualitative-study
#19
Fahimeh Ranjbar, Zahra Behboodi-Moghadam, Leili Borimnejad, Saeed Reza Ghaffari, Mohammad Mehdi Akhondi
BACKGROUND: Assisted reproductive technologies (ARTs) are complicated and stressful techniques and the social and cultural norms are major obstacles against their use. Many qualitative studies have been done in the field of women's experiences of infertility, but less is known about the experiences of infertile women seeking assisted pregnancy. The aim of this study was to understand and describe the experience of women who have used assisted reproductive technologies for their current pregnancy...
October 2015: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/27104313/tropisetron-suppresses-colitis-associated-cancer-in-a-mouse-model-in-the-remission-stage
#20
Hossein Amini-Khoei, Majid Momeny, Alireza Abdollahi, Ahmad Reza Dehpour, Shayan Amiri, Arya Haj-Mirzaian, Seyed Mohammad Tavangar, Seyed Hamid Ghaffari, Reza Rahimian, Shahram Ejtemaei Mehr
Patients with inflammatory bowel disease (IBD) have a high risk for development of colitis-associated cancer (CAC). Serotonin is a neurotransmitter produced by enterochromaffin cells of the intestine. Serotonin and its receptors, mainly 5-HT3 receptor, are overexpressed in IBD and promote development of CAC through production of inflammatory cytokines. In the present study, we demonstrated the in vivo activity of tropisetron, a 5-HT3 receptor antagonist, against experimental CAC. CAC was induced by azoxymethane (AOM)/dextran sodium sulfate (DDS) in BALB/c mice...
April 19, 2016: International Immunopharmacology
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