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ecg changes in stroke

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https://www.readbyqxmd.com/read/29681583/minor-electrocardiographic-st-t-change-and-risk-of-stroke-in-the-general-japanese-population
#1
Joji Ishikawa, Hideo Hirose, Joseph E Schwartz, Shizukiyo Ishikawa
BACKGROUND: Minor ST-T changes are frequently observed on the electrocardiogram (ECG), but the risk of stroke associated with such changes is unclear.Methods and Results:In 10,642 subjects from the Japanese general population, we evaluated minor and major ST-T changes (major ST depression ≥0.1 mV) on ECGs obtained at annual health examinations. At baseline, minor ST-T changes were found in 10.7% of the subjects and 0.5% had major ST-T changes. Minor ST-T changes were associated with older age, female gender, higher systolic blood pressure, presence of hyperlipidemia, and use of antihypertensive medication...
April 20, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29645285/cardiovascular-safety-of-the-%C3%AE-3-adrenoceptor-agonist-mirabegron-and-the-antimuscarinic-agent-solifenacin-in-the-synergy-trial
#2
William B White, Christopher Chapple, Christian Gratzke, Sender Herschorn, Dudley Robinson, Jeffrey Frankel, Arwin Ridder, Matthias Stoelzel, Asha Paireddy, Robert van Maanen, Michael A Weber
There have been concerns that treatment of overactive bladder with β3 -adrenoceptor agonists may potentially have detrimental cardiovascular (CV) side effects. We evaluated the CV safety of mirabegron, a β3 -adrenoceptor agonist, alone and in combination therapy with the antimuscarinic agent solifenacin. The SYNERGY trial was a multinational, multicenter, randomized, double-blind, parallel-group, placebo and active-controlled phase 3 trial. Patients were randomized to receive solifenacin 5 mg + mirabegron 50 mg (combination 5 + 50 mg), solifenacin 5 mg + mirabegron 25 mg (combination 5 + 25 mg), solifenacin 5 mg monotherapy, mirabegron 25 mg monotherapy, mirabegron 50 mg monotherapy, or placebo for a 12-week double-blind treatment period...
April 12, 2018: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29604089/electrocardiographic-left-ventricular-hypertrophy-predicts-recurrence-of-atrial-arrhythmias-after-catheter-ablation-of-paroxysmal-atrial-fibrillation
#3
Song-Nan Li, Lu Wang, Jian-Zeng Dong, Rong-Hui Yu, De-Yong Long, Ri-Bo Tang, Cai-Hua Sang, Chen-Xi Jiang, Nian Liu, Rong Bai, Xin Du, Chang-Sheng Ma
AIMS: Left ventricular hypertrophy (LVH) is an independent predictor of new-onset atrial fibrillation. Whether LVH can predict the recurrence of arrhythmia after radiofrequency catheter ablation (RFCA) in patients with paroxysmal atrial fibrillation (PAF) remains unclear. METHODS: A total of 436 patients with PAF undergoing first RFCA were consecutively enrolled and clustered into 2 groups based on electrocardiogram (ECG) findings: non ECG LVH (218 patients), ECG LVH (218 patients)...
March 31, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29580658/transcutaneous-auricular-vagus-nerve-stimulation-with-concurrent-upper-limb-repetitive-task-practice-for-poststroke-motor-recovery-a-pilot-study
#4
Jessica N Redgrave, Lucy Moore, Tosin Oyekunle, Maryam Ebrahim, Konstantinos Falidas, Nicola Snowdon, Ali Ali, Arshad Majid
BACKGROUND: Invasive vagus nerve stimulation (VNS) has the potential to enhance the effects of physiotherapy for upper limb motor recovery after stroke. Noninvasive, transcutaneous auricular branch VNS (taVNS) may have similar benefits, but this has not been evaluated in stroke recovery. We sought to determine the feasibility of taVNS delivered alongside upper limb repetitive task-specific practice after stroke and its effects on a range of outcome measures evaluating limb function. MATERIALS AND METHODS: Thirteen participants at more than 3 months postischemic stroke with residual upper limb dysfunction were recruited from the community of Sheffield, United Kingdom (October-December 2016)...
March 23, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29514809/association-of-atrial-fibrillation-with-cognitive-decline-and-dementia-over-20-years-the-aric-ncs-atherosclerosis-risk-in-communities-neurocognitive-study
#5
Lin Y Chen, Faye L Norby, Rebecca F Gottesman, Thomas H Mosley, Elsayed Z Soliman, Sunil K Agarwal, Laura R Loehr, Aaron R Folsom, Josef Coresh, Alvaro Alonso
BACKGROUND: Previous studies have reported that atrial fibrillation (AF) is associated with cognitive decline and dementia. These studies, however, had limited follow-up, were based mostly on white and highly selected populations, and did not account for attrition. We evaluated the association of incident AF with 20-year change in cognitive performance (accounting for attrition) and incident dementia in the ARIC (Atherosclerosis Risk in Communities) Study. METHODS AND RESULTS: We analyzed data from 12 515 participants (mean age, 56...
March 7, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29505511/cardiovascular-risk-factors-in-patients-with-combined-central-retinal-vein-occlusion-and-cilioretinal-artery-occlusion-case-report
#6
Andrzej Grzybowski, Waldemar Elikowski, Magdalena Gaca-Wysocka
RATIONALE: To analyze cardiovascular risk factors and comorbidity of acute unilateral visual loss due to combined central retinal vein occlusion (CRVO) and cilioretinal artery occlusion (CLRAO). PATIENT CONCERNS: Among patients with retinal vein or artery occlusion hospitalized at the Department of Ophthalmology between January 2011 and August 2017, subjects with combined CRVO/CLRAO were selected. All of them underwent ophthalmologic and cardiologic examination, including fluorescein angiography, optical coherence tomography, 12-lead electrocardiogram, transthoracic and transesophageal echocardiography, carotid Doppler sonography, cerebral magnetic resonance imaging, and a panel of laboratory tests...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29503381/the-national-integrated-project-for-prospective-observation-of-non-communicable-disease-and-its-trends-in-the-aged-2010-nippon-data2010-objectives-design-and-population-characteristics
#7
Aya Kadota, Nagako Okuda, Takayoshi Ohkubo, Tomonori Okamura, Nobuo Nishi, Hirotsugu Ueshima, Akira Okayama, Katsuyuki Miura
BACKGROUND: The structure and risk factors for cardiovascular diseases (CVD) in Japan may change because lifestyle, particularly nutrition, socioeconomic status, and medical care, which affect CVD, may markedly change over time. Therefore, a new prospective cohort study on a representative general Japanese population based on national surveys is required. METHODS: In November 2010, the baseline survey of the National Integrated Project for Prospective Observation of Non-communicable Disease and its Trends in the Aged 2010 (NIPPON DATA2010) was performed with the National Health and Nutrition Survey of Japan (NHNS2010) in 300 randomly selected districts throughout Japan...
2018: Journal of Epidemiology
https://www.readbyqxmd.com/read/29488810/relative-peak-exercise-oxygen-pulse-is-related-to-sudden-cardiac-death-cardiovascular-and-all-cause-mortality-in-middle-aged-men
#8
Jari A Laukkanen, Claudio Gil S Araújo, Sudhir Kurl, Hassan Khan, Sae Y Jae, Marco Guazzi, Setor K Kunutsor
Background Preliminary evidence suggests that peak exercise oxygen pulse - peak oxygen uptake/heart rate-, a variable obtained during maximal cardiopulmonary exercise testing and a surrogate of stroke volume, is a predictor of mortality. We aimed to assess the associations of peak exercise oxygen pulse with sudden cardiac death, fatal coronary heart disease and cardiovascular disease and all-cause mortality. Design A prospective study. Methods Peak exercise oxygen pulse was assessed in a maximal cycling test at baseline in 2227 middle-aged men of the Kuopio Ischaemic Heart Disease cohort study using expired gas variables and electrocardiograms...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29466210/-elevated-level-of-the-natriuretic-peptide-among-adult-population-in-regions-participating-in-the-esse-rf-study-and-its-association-with-cardiovascular-diseases-and-risk-factors
#9
S A Shalnova, A E Imaeva, A D Deev, V A Metelskaya, G A Muromtseva, A O Konradi, V P Masenko, A Y Efanov, N V Kulakova, O P Rotar, I A Trubacheva, A A Shabunova, E V SHlyakhto, S A Boytsov
AIM: to study associations between elevated blood plasma concentration of N-terminal pro-brain natriuretic peptide (NT-proBNP), risk factors and cardiovascular diseases (CVD) in samples of adult population of Russian Federation (RF) aged 25-64 years. MATERIALS AND METHODS: We analyzed data of examination of representative samples of population of 5 regions of RF obtained within the framework of the multicenter ESSE-RF study (2012-2013). Number of examined subjects was 8 077 (3 176 men)...
December 2017: Kardiologiia
https://www.readbyqxmd.com/read/29373611/accuracy-and-reliability-of-noninvasive-stroke-volume-monitoring-via-ecg-gated-3d-electrical-impedance-tomography-in-healthy-volunteers
#10
Fabian Braun, Martin Proença, Andy Adler, Thomas Riedel, Jean-Philippe Thiran, Josep Solà
Cardiac output (CO) and stroke volume (SV) are parameters of key clinical interest. Many techniques exist to measure CO and SV, but are either invasive or insufficiently accurate in clinical settings. Electrical impedance tomography (EIT) has been suggested as a noninvasive measure of SV, but inconsistent results have been reported. Our goal is to determine the accuracy and reliability of EIT-based SV measurements, and whether advanced image reconstruction approaches can help to improve the estimates. Data were collected on ten healthy volunteers undergoing postural changes and exercise...
2018: PloS One
https://www.readbyqxmd.com/read/29357508/early-blood-pressure-response-to-isometric-exercise-is-attenuated-in-obese-individuals-who-have-undergone-bariatric-surgery
#11
Jacqueline K Limberg, Winston Guo, Michael J Joyner, Nisha Charkoudian, Timothy B Curry
Blood pressure (BP) reactivity is predictive of the development of cardiovascular disease. We hypothesized that the BP response at the onset of isometric handgrip exercise would occur earlier and to a lesser degree in individuals who underwent bariatric surgery compared with obese adults and that the reliance on total peripheral resistance (TPR) would be attenuated. Twenty-six individuals (7 nonobese, 11 obese, 8 postbariatric surgery) completed isometric handgrip exercise (40% maximum voluntary contraction) to exhaustion...
April 1, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29198129/hemodynamic-effects-of-epinephrine-in-rats-evaluation-by-impedance-cardiography
#12
C H Turkseven, E Pekoglu, B Buyukakilli
BACKGROUND AND OBJECTIVES: This study was aimed to examine how inotropic effects of intravenously injected epinephrine change thoracic impedance measurements and to reveal the possible effects of this change on other hemodynamic parameters by using the technique of impedance cardiography. METHODS: 10 male Wistar Albino rats were divided into two equal groups: control and epinephrine. 0.2 mg/kg of epinephrine was administered to the rats in the epinephrine group via the tail vein...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/29197472/frequency-of-inverted-electrocardiographic-t-waves-cerebral-t-waves-in-patients-with-acute-strokes-and-their-relation-to-left-ventricular-wall-motion-abnormalities
#13
Jeremy Stone, Victor Mor-Avi, Agnieszka Ardelt, Roberto M Lang
Transient, symmetric, and deep inverted electrocardiogram (ECG) T waves in the setting of stroke, commonly referred to as cerebral T waves, are rare, and the underlying mechanism is unclear. Our study aimed to test the hypothesis that cerebral T waves are associated with transient cardiac dysfunction. This retrospective study included 800 patients admitted with the primary diagnosis of hemorrhagic or ischemic stroke. ECGs were examined for cerebral T waves, defined as T-wave inversion of ≥5 mm depth in ≥4 contiguous precordial leads...
January 1, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29171136/prevalence-and-prognostic-impact-of-electrocardiographic-abnormalities-in-outpatients-with-extracardiac-artery-disease
#14
Per Hysing, Tommy Jonason, Jerzy Leppert, Pär Hedberg
Identifying cardiac disease in patients with extracardiac artery disease (ECAD) is essential for clinical decision-making. Electrocardiography (ECG) is an easily accessible tool to unmask subclinical cardiac disease and to risk stratify patient with or without manifest cardiovascular disease (CV). We aimed to examine the prevalence and prognostic impact of ECG changes in outpatients with ECAD. Outpatients with carotid or lower extremity artery disease (n = 435) and community-based controls (n = 397) underwent resting ECG...
November 24, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29167390/early-elevated-troponin-levels-after-ischemic-stroke-suggests-a-cardioembolic-source
#15
Shadi Yaghi, Andrew D Chang, Brittany A Ricci, Mahesh V Jayaraman, Ryan A McTaggart, Morgan Hemendinger, Priya Narwal, Katarina Dakay, Brian Mac Grory, Shawna M Cutting, Tina M Burton, Christopher Song, Emile Mehanna, Matthew Siket, Tracy E Madsen, Michael Reznik, Alexander E Merkler, Michael P Lerario, Hooman Kamel, Mitchell S V Elkind, Karen L Furie
BACKGROUND AND PURPOSE: Elevated cardiac troponin is a marker of cardiac disease and has been recently shown to be associated with embolic stroke risk. We hypothesize that early elevated troponin levels in the acute stroke setting are more prevalent in patients with embolic stroke subtypes (cardioembolic and embolic stroke of unknown source) as opposed to noncardioembolic subtypes (large-vessel disease, small-vessel disease, and other). METHODS: We abstracted data from our prospective ischemic stroke database and included all patients with ischemic stroke during an 18-month period...
January 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29130017/clinical-characteristics-management-and-outcomes-of-suspected-poststroke-acute-coronary-syndrome
#16
Sylvia Marie Biso, Marvin Lu, Toni Anne De Venecia, Supakanya Wongrakpanich, Mary Rodriguez-Ziccardi, Sujani Yadlapati, Marina Kishlyansky, Harish Seetha Rammohan, Vincent M Figueredo
Background: Acute coronary syndrome (ACS) can complicate acute ischemic stroke, causing significant morbidity and mortality. To date, literatures that describe poststroke acute coronary syndrome and its morbidity and mortality burden are lacking. Methods: This is a single center, retrospective study where clinical characteristics, cardiac evaluation, and management of patients with suspected poststroke ACS were compared and analyzed for their association with inpatient mortality and 1-year all-cause mortality...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/29121723/atrial-fibrillation-and-use-of-antithrombotic-medications-in-older-people-a-population-based-study
#17
Mozhu Ding, Laura Fratiglioni, Kristina Johnell, Johan Fastbom, Maria Ljungdahl, Chengxuan Qiu
BACKGROUND: Trends in the use of antithrombotic drugs in elderly patients with atrial fibrillation (AF) are largely unknown. We estimated the prevalence of AF in an older population, and examined whether use of anticoagulant and antiplatelet drugs in older AF patients has changed over time. METHODS: Data from the population-based Swedish National study on Aging and Care in Kungsholmen (n=3363, age≥60years, 64.9% women) were used (2001-2004 and 2007-2010). AF cases were identified through 12-lead electrocardiogram, physician examinations, and patient register records (ICD-10 code I48)...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29117189/cardiac-cycle-synchronized-electrical-muscle-stimulator-for-lower-limb-training-with-the-potential-to-reduce-the-heart-s-pumping-workload
#18
Ken-Ichiro Sasaki, Hiroo Matsuse, Ryuji Akimoto, Shiro Kamiya, Toshio Moritani, Motoki Sasaki, Yuta Ishizaki, Masanori Ohtsuka, Takaharu Nakayoshi, Takafumi Ueno, Naoto Shiba, Yoshihiro Fukumoto
BACKGROUND: The lower limb muscle may play an important role in decreasing the heart's pumping workload. Aging and inactivity cause atrophy and weakness of the muscle, leading to a loss of the heart-assisting role. An electrical lower limb muscle stimulator can prevent atrophy and weakness more effectively than conventional resistance training; however, it has been reported to increase the heart's pumping workload in some situations. Therefore, more effective tools should be developed...
2017: PloS One
https://www.readbyqxmd.com/read/29101116/counterclockwise-and-clockwise-rotation-of-qrs-transitional-zone-prospective-correlates-of-change-and-time-varying-associations-with-cardiovascular-outcomes
#19
Siddharth Patel, Lucia Kwak, Sunil K Agarwal, Larisa G Tereshchenko, Josef Coresh, Elsayed Z Soliman, Kunihiro Matsushita
BACKGROUND: A few studies have recently reported clockwise and counterclockwise rotations of QRS transition zone as predictors of mortality. However, their prospective correlates and associations with individual cardiovascular disease (CVD) outcomes are yet to be investigated. METHODS AND RESULTS: Among 13 567 ARIC (Atherosclerosis Risk in Communities) study participants aged 45 to 64 years, we studied key correlates of changes in the status of clockwise and counterclockwise rotation over time as well as the association of rotation status with incidence of coronary heart disease (2408 events), heart failure (2196 events), stroke (991 events), composite CVD (4124 events), 898 CVD deaths, and 3469 non-CVD deaths over 23 years of follow-up...
November 3, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29082335/atrial-fibrillation-trial-to-evaluate-real-world-procedures-for-their-utility-in-helping-to-lower-stroke-events-after-pulse-study-protocol-for-a-randomized-controlled-trial
#20
Tsung-Ta Hsieh, Meng Lee, Wen-Yi Huang, Sung-Chun Tang, Sheng-Feng Sung, Kuo-Husan Chang, Jiann-Der Lee, Tsong-Hai Lee, Yung-Sung Huang, Jiann-Shing Jeng, Chang-Min Chung, Yi-Ling Wu, Bruce Ovbiagele
BACKGROUND: Enhancing detection of undiagnosed atrial fibrillation (AF) in hospitalized patients with a recent ischemic stroke is important because of the treatment implications; especially since presence of paroxysmal AF may not be picked up in a single 12-lead electrocardiogram (ECG) test. While several trials have shown improved detection of AF with prolonged ECG monitoring, this strategy is associated with relatively high cost, labor intensity, and patient inconvenience, thereby making it challenging to routinely implement in all hospitals...
June 2017: Contemporary Clinical Trials Communications
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