Lu Yang, Pengqi Hou, Jingyi Wei, Bingxin Li, Aijun Gao, Zhiqin Yuan
Gold nanoclusters (Au NCs) with bright emission and unique chemical reactivity characters have been widely applied for optical sensing and imaging. With a combination of surface modifications, effective therapeutic treatments of tumors are realized. In this review, we summarize the recently adopted biosensing and therapy events based on Au NCs. Homogeneous and fluorometric biosensing systems toward various targets, including ions, small molecules, reactive oxygen species, biomacromolecules, cancer cells, and bacteria, in vitro and in vivo, are presented by turn-off, turn-on, and ratiometric tactics...
April 1, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry