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https://www.readbyqxmd.com/read/29773779/prospects-for-us-cuba-cooperation-in-gastroenterology-hepatology-and-liver-transplantation
#1
Marlen I Castellanos-Fernández, Mirtha Infante-Velázquez, Enrique Arús-Soler, Marcelo Kugelmas, Ramón Bataller, Ramón Villamil-Martínez, Zaily Dorta-Guridi, Caridad Ruenes-Domenech
Gastroenterology, hepatology and liver transplant exchanges between the USA and Cuba have mainly consisted of scientific events and short visits. This has facilitated Cuba's inclusion in recognized scientific organizations, familiarity with Cuba's biotech products for treatment of liver disease, and access by Cuban professionals to the highest level of scientific information for clinical practice. It has also given health professionals in the US a more accurate picture of Cuba's health sector. The results of the Global Alcoholic Liver Disease Survey, which included Cuba and was designed and coordinated in the USA, opened doors to joint research and scientific publications...
April 2018: MEDICC Review
https://www.readbyqxmd.com/read/29744626/successful-abdominal-wound-closure-for-treatment-of-severe-peritonitis-using-negative-pressure-wound-therapy-with-continuous-mesh-fascial-traction-a-case-report
#2
Hideki Kogo, Jun Hagiwara, Shiei Kin, Eiji Uchida
BACKGROUND: Surgery for severe peritonitis often entails difficult wound closure and may require open abdominal management due to gut edema and/or concern of abdominal compartment syndrome. Negative pressure wound therapy (NPWT) is known to have good outcomes for wound closure after surgery for severe peritonitis. NPWT with continuous mesh fascial traction may result in even better outcomes, especially for fascial closure. CASE PRESENTATION: An 81-year-old man was hospitalized for abdominal pain...
May 9, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29731657/prediction-of-acute-kidney-injury-in-cirrhotic-patients-a-new-score-combining-renal-liver-and-inflammatory-markers
#3
Joana Gameiro, José Agapito Fonseca, Joana Monteiro Dias, Maria João Melo, Sofia Jorge, José Velosa, José António Lopes
Introduction: Acute kidney injury (AKI) is common in hospitalized patients with cirrhosis and is associated with poor prognosis. A risk prediction score combining values easily measured at admission could be valuable to stratify patients for prevention, monitoring and early intervention, ultimately improving patient care and outcomes. The aim of this study was to develop a risk score for AKI in a cohort of cirrhotic patients. Patients and methods: We cross-examined the data from a retrospective analysis of 186 patients with cirrhosis admitted to the Gastroenterology and Hepatology Service of Centro Hospitalar Lisboa Norte from January 2003 to December 2005...
2018: International Journal of Nephrology and Renovascular Disease
https://www.readbyqxmd.com/read/29700095/management-of-decompensated-cirrhosis
#4
Dina Mansour, Stuart McPherson
Decompensated cirrhosis is a common reason for admission to the acute medical unit, and such patients typically have complex medical needs and are at high risk of in-hospital death. It is therefore vital that these patients receive appropriate investigations and management as early as possible in their patient journey. Typical presenting clinical features include jaundice, ascites, hepatic encephalopathy, hepato-renal syndrome or variceal haemorrhage. A careful history, examination and investigations can help identify the precipitating cause (infections, gastrointestinal bleeding, high alcohol intake / alcohol-related hepatitis or drug-induced liver injury), so appropriate treatment can be given...
April 1, 2018: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29696062/iron-deficiency-in-a-tertiary-gastroenterology-center-in-romania-prevalence-and-significancy
#5
Carmen Monica Preda, Doina Proca, Irina Sandra, Boroka Claudia Horeanga, Larisa Elena Fulger, Teodora Manuc, Ion Bancila, Oana Elena Balas, Mircea Manuc, Mircea Diculescu, Cristian Baicus, Cristian Tieranu, Ileana Constantinescu
Introduction: Iron deficiency has been known to cause significant functional impairment, lower quality of life and higher morbidity and mortality. The aim of this study was to estimate the prevalence and significance of iron deficiency in our patients and medical staff. Material and methods: We performed a prospective cross-sectional study: In July 2016, 383 persons were screened for the presence of iron deficiency (ID): 325 patients and 58 people from the medical staff. Transferrin saturation (TSAT), serum ferritin (SF) and complete blood count were performed...
January 2018: Journal of Medicine and Life
https://www.readbyqxmd.com/read/29690960/is-hepatovenocaval-syndrome-a-different-entity-from-budd-chiari-syndrome-in-children
#6
Nadia Waheed, Huma Arshad Cheema, Hassan Suleman, Iqra Mushtaq, Zafar Fayyaz, Nadeem Anjum
OBJECTIVE: To differentiate between clinical and demographic spectrum, and outcome in hepatovenocaval syndrome (HVCS) and Budd-Chiari syndrome (BCS). STUDY DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: Division of Pediatric Gastroenterology, Hepatology and Nutrition, The Children Hospital, Lahore, from January 2014 to January 2017. METHODOLOGY: All children less than 18 years of age, presenting with ascites and visible veins over abdomen, flanks and back were enrolled in the study...
May 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29690722/-dynamic-investigation-of-nutritional-risk-in-patients-with-malignant-tumor-during-hospitalization
#7
M W Zhu, J M Wei, W Chen, X Yang, H Y Cui, S N Zhu, P P Zhang, J Xiong, D F Zheng, H J Song, X Y Liang, L Zhang, W Y Xu, H B Wang, G Q Su, L J Feng, T Chen, Y D Wu, H Li, J Q Sun, Y Shi, B D Tong, S M Zhou, X Y Wang, Y H Huang, B M Zhang, J Xu, H Y Zhang, G L Chang, Z Y Jia, S F Chen, J Hu, X W Zhang, H Wang, Z D Li, Y Y Gao, B Gui
Objective: To prospectively investigate the changes in nutritional status of patients with malignant tumors during hospitalization by using nutritional risk screening (NRS2002), and to analyze the correlation between the nutritional status and clinical outcomes . Methods: This was a prospective and parallel research done by multi-center collaboration from 34 hospitals in China from June to September 2014.Hospitalized patients with malignant tumors inthese departments (Department of Gastroenterology, respiratory medicine, oncology, general surgery, thoracic surgery and geriatrics)were investigated...
April 10, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29688336/nonalcoholic-fatty-liver-disease-in-inflammatory-bowel-disease-prevalence-and-risk-factors
#8
Principi Mariabeatrice, Iannone Andrea, Losurdo Giuseppe, Mangia Michela, Shahini Endrit, Albano Francesca, Salvatore Fabio Rizzi, Rosa Federica La Fortezza, Lovero Rosa, Contaldo Antonella, Barone Michele, Leandro Gioacchino, Ierardi Enzo, Di Leo Alfredo
Background: Nonalcoholic fatty liver disease (NAFLD) is common in inflammatory bowel diseases (IBD). Herein, NAFLD prevalence and risk factors in a large IBD cohort were evaluated and compared to that of a non-IBD sample. Methods: Crohn's disease/ulcerative colitis outpatients referred to IBD service of our Gastroenterology Unit were enrolled. Subjects affected by functional and motor gastrointestinal disorders, in whom IBD was ruled out, referred to general outpatient service in the same area, were considered as nonIBD group...
April 23, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29681874/alexithymia-in-gastroenterology-and-hepatology-a-systematic-review
#9
Danilo Carrozzino, Piero Porcelli
Background: Alexithymia is a multifaceted personality construct that represents a deficit in the cognitive processing of emotions and is currently understood to be related to a variety of medical and psychiatric conditions. The present review aims to investigate the relationship of alexithymia with gastrointestinal (GI) disorders as functional gastrointestinal disorders (FGID, as irritable bowel syndrome (IBS) and functional dyspepsia) and inflammatory bowel disease (IBD) [ulcerative colitis (UC) and Crohn's disease (CD)] and liver diseases as chronic hepatitis C (CHC), cirrhosis, and liver transplantation...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29623600/significance-of-glypican-3-in-early-detection-of-hepatocellular-carcinoma-in-cirrhotic-patients
#10
Ahmed M Tahon, Magdy Z El-Ghanam, Samy Zaky, Tarek Mostafa Emran, Ali M Bersy, Fathiya El-Raey, Elsayed A Z, Amr M El Kharsawy, Dina Johar
BACKGROUND: Egypt has high incidence of hepatocellular carcinoma (HCC). This is due to wide spread of hepatitis C virus (HCV) infection which is responsible for most of the cases of liver cirrhosis. The major diagnostic techniques for HCC include serum markers and various imaging modalities. Glypican 3 (GPC3) protein is highly expressed in HCC, but not in normal liver tissue. The significance of GPC3 as a predictor or diagnostic tool for human tumors other than HCC is unclear. AIM: To quantitatively assess the role of GPC3 in diagnosis of HCC in comparison to α-fetoprotein (AFP), ultrasonography (US), and computerized tomography (CT)...
April 6, 2018: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/29621059/presence-of-hepatitis-b-surface-antibody-in-addition-to-hepatitis-b-core-antibody-confers-protection-against-hepatitis-b-virus-infection-in-hepatitis-b-surface-antigen-negative-patients-undergoing-kidney-transplantation
#11
Jae Wan Jeon, So Mi Kim, Hyungjin Cho, Chung Hee Baek, Hyosang Kim, Sung Shin, Young Hoon Kim, Duck Jong Han, Soon Bae Kim
BACKGROUND: The American Gastroenterological Association (AGA) and European Association for the Study of the Liver (EASL) recommend that hepatitis B surface antigen (HBsAg)-negative and hepatitis B core antibody (anti-HBc)-positive patients who receive immunosuppression should be monitored for hepatitis B virus (HBV) infection regardless of hepatitis B surface antibody (anti-HBs) status. However, anti-HBs may provide protection against infection. To investigate whether the presence of anti-HBs in addition to anti-HBc confers protection, we classified HBsAg(-) kidney transplantation (KT) patients into 4 groups according to anti-HBc and anti-HBs status, and compared the HBV infection rate between the anti-HBc(+)anti-HBs(+) group and the other 3 groups...
April 5, 2018: Transplantation
https://www.readbyqxmd.com/read/29596163/chapter-3-the-european-society-for-paediatric-gastroenterology-hepatology-and-nutrition-in-recent-years
#12
Berthold Koletzko, Raanan Shamir, Ilse Broekaert, Riccardo Troncone
The European Society for Paediatric Gastroenterology, Hepatology and Nutrition has experienced an amazing development in the 50 years of its existence. It grew from a small group of 36 friends who held an informal meeting with some 20 oral presentations to share and discuss their clinical and research work, to a large, multiprofessional society that sets widely recognized standards for clinical care and policy and hosts the world's largest congress of Paediatric Gastroenterology, Hepatology and Nutrition with more than 4500 delegates from 100 countries...
April 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29593060/the-british-society-of-gastroenterology-uk-pbc-primary-biliary-cholangitis-treatment-and-management-guidelines
#13
Gideon M Hirschfield, Jessica K Dyson, Graeme J M Alexander, Michael H Chapman, Jane Collier, Stefan Hübscher, Imran Patanwala, Stephen P Pereira, Collette Thain, Douglas Thorburn, Dina Tiniakos, Martine Walmsley, George Webster, David E J Jones
Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury, cholestasis and progressive fibrosis can culminate over time in an end-stage biliary cirrhosis. Both genetic and environmental influences are presumed relevant to disease initiation. PBC is most prevalent in women and those over the age of 50, but a spectrum of disease is recognised in adult patients globally; male sex, younger age at onset (<45) and advanced disease at presentation are baseline predictors of poorer outcome...
March 28, 2018: Gut
https://www.readbyqxmd.com/read/29549474/contributions-of-magnetic-resonance-imaging-to-gastroenterological-practice-mris-for-gis
#14
Christopher G Roth, Dina Halegoua-De Marzio, Flavius F Guglielmo
MRI has transformed from the theoretical, investigative realm to mainstream clinical medicine over the past four decades and has become a core component of the diagnostic toolbox in the practice of gastroenterology (GI). Its success is attributable to exquisite contrast and the ability to isolate specific proton species through the use of different pulse sequences (i.e., T1-weighted, T2-weighted, diffusion-weighted) and exploiting extracellular and hepatobiliary contrast agents. Consequently, MRI has gained preeminence in various GI clinical applications: liver and pancreatic lesion evaluation and detection, liver transplantation evaluation, pancreatitis evaluation, Crohn's disease evaluation (using MR enterography) rectal cancer staging and perianal fistula evaluation...
May 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29519502/ngm282-for-treatment-of-non-alcoholic-steatohepatitis-a-multicentre-randomised-double-blind-placebo-controlled-phase-2-trial
#15
Stephen A Harrison, Mary E Rinella, Manal F Abdelmalek, James F Trotter, Angelo H Paredes, Hays L Arnold, Marcelo Kugelmas, Mustafa R Bashir, Mark J Jaros, Lei Ling, Stephen J Rossi, Alex M DePaoli, Rohit Loomba
BACKGROUND: Non-alcoholic steatohepatitis is a chronic liver disease characterised by the presence of hepatic steatosis, inflammation, and hepatocellular injury, for which no Food and Drug Administration (FDA)-approved treatment exists. FGF19 is a hormone that regulates bile acid synthesis and glucose homoeostasis. We aimed to assess the safety and efficacy of NGM282, an engineered FGF19 analogue, for the treatment of non-alcoholic steatohepatitis. METHODS: In this randomised, double-blind, placebo-controlled, phase 2 study, we recruited patients aged 18-75 years with biopsy-confirmed non-alcoholic steatohepatitis as defined by the non-alcoholic steatohepatitis clinical research network histological scoring system, from hospitals and gastroenterology and liver clinics in Australia and the USA...
March 24, 2018: Lancet
https://www.readbyqxmd.com/read/29513678/neurological-manifestations-in-chronic-hepatitis-c-patients-receiving-care-in-a-reference-hospital-in-sub-saharan-africa-a-cross-sectional-study
#16
N Y Mapoure, M N Budzi, S A F B Eloumou, A Malongue, C Okalla, H N Luma
BACKGROUND: Chronic hepatitis C infection is a major public health concern, with a high burden in Sub-Saharan Africa. There is growing evidence that chronic hepatitis C virus (HCV) infection causes neurological complications. This study aimed at assessing the prevalence and factors associated with neurological manifestations in chronic hepatitis C patients. METHODS: Through a cross-sectional design, a semi-structured questionnaire was used to collect data from consecutive chronic HCV infected patients attending the outpatient gastroenterology unit of the Douala General Hospital (DGH)...
2018: PloS One
https://www.readbyqxmd.com/read/29488140/health-promoting-behaviors-benefit-the-mental-health-of-cirrhotic-outpatients
#17
Hui-Chuan Huang, Kuan-Chia Lin, Chia-Shin Wu, Nae-Fang Miao, Ming-Yao Chen
PURPOSE: The objectives of this study were to survey the frequency of engaging in a health-promoting lifestyle in patients with liver cirrhosis, and examine the mediating effects of a health-promoting lifestyle on relationships of symptoms and psychological distress with the quality of life (QOL). METHODS: A cross-sectional study was conducted to recruit 148 cirrhotic outpatients from the gastroenterology outpatient department of one medical university hospital...
February 27, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29475442/correction-to-a-vicious-circle-between-insulin-resistance-and-inflammation-in-nonalcoholic-fatty-liver-disease
#18
Zhonge Chen, Rong Yu, Ying Xiong, Fangteng Du, Shuishan Zhu
Following publication of the original article [1], the corresponding author reported that he had mistyped the first author's unit. The affiliation of Zhonge Chen, "Medical Center of the Graduate School, Nanchang University, China", should be changed to "Department of Gastroenterology, Second Affiliated Hospital, Nanchang University Nanchang, China". All the other authors have agreed to this change. The corrected version should be as follows.
February 23, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29459807/-primary-biliary-cholangitis-part-1-state-of-the-art-epidemiology-physiopathology-and-clinical-manifestations
#19
Diego Andrés Rodríguez Lugo, Jorge Julián Coronado Tovar, Giovana Alejandra Solano Villamarin, Wiliam Otero Regino
Primary biliary cholangitis (PBC) is a chronic autoimmune cholangiopathy characterized by a selective destruction of biliary epithelial cells of small and medium caliber hepatic ducts, which mainly affects women. The main symptoms are fatigue and pruritus, however, a large proportion of patients may be asymptomatic. The diagnosis is based on AMA titers >1:40, alkaline phosphatase >1.5 times the upper limit for more than 24 weeks and compatible liver histology. It is associated with multiple autoimmune diseases mainly extrahepatic, thyroid diseases, bone diseases, among others...
October 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/29451278/united-european-gastroenterology-week-uegw-2017-25th-annual-conference-october-28-november-1-2017-barcelona-spain
#20
E Torramadé
The 25th United European Gastroenterology Week (UEGW), the largest European conference centered on diseases of the stomach, bowel, esophagus, liver, pancreas and gallbladder, was held in Barcelona, Spain. This 5-day meeting attracted over 13,000 delegates to share recent research in the treatment of gastrointestinal and liver diseases. The conference provided teaching material, workshops and live sessions to all the attendants. The reports will cover the latest research into treatments for these diseases.
November 2017: Drugs of Today
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