Francesco Di Pierro, Ruqqia Sultana, Amna Zia Eusaph, Saida Abrar, Mahroo Bugti, Fauzia Afridi, Umer Farooq, Somia Iqtadar, Fareeha Ghauri, Syeda Makhduma, Shazia Nourin, Ayesha Kanwal, Aasiya Bano, Ali Akbar Bugti, Shah Mureed, Ayesha Ghazal, Romana Irshad, Martino Recchia, Alexander Bertuccioli, Pietro Putignano, Antonella Riva, Luigina Guasti, Nicola Zerbinati, Amjad Khan
Background: Berberine is a poorly absorbed natural alkaloid widely used as nutraceutical to counteract diarrhoea and to lower cholesterol and hyperglycaemia. It has also been reported to reduce signs and symptoms of polycystic ovary syndrome (PCOS). Objective: To explore, through a multi-centric, randomized, controlled and prospective study, the possible role played by a form berberine that is more easily absorbed (Berberine Phytosome® , BP) in 130 Pakistani women with a diagnosis of PCOS and fertility problems due to menstrual and ovary abnormalities...
2023: Frontiers in Pharmacology