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https://www.readbyqxmd.com/read/29430771/factors-associated-with-romantic-relationship-formation-difficulties-in-women-with-breast-cancer
#1
L-K Shaw, K A Sherman, J Fitness, E Elder
OBJECTIVE: Many un-partnered women report difficulty in forming romantic relationships after breast cancer, characterized by high dating-related anxiety and low perceived interpersonal competence. This study examined the relationship between poor body image (appearance investment and body dissatisfaction) and self-compassion, and women's ability to form romantic relationships post-breast cancer. METHODS: Women (N=152) diagnosed with breast cancer, who were either un-partnered and expressed interest in romantic dating, or who had commenced a relationship post-diagnosis, completed an online survey...
February 12, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29429145/impact-of-an-interprofessional-primary-care-training-on-fear-of-cancer-recurrence-on-clinicians-knowledge-self-efficacy-anticipated-practice-behaviors-and-attitudes-toward-survivorship-care
#2
Julie Berrett-Abebe, Tamara Cadet, Larissa Nekhlyudov, Joan Vitello, Peter Maramaldi
There are an estimated 15.5 million cancer survivors in the United States, with numbers projected to increase. Many cancer survivors are receiving survivorship care in primary care settings, yet primary care providers report a need for additional training on addressing medical and psychosocial concerns of cancer survivors. This paper presents findings from a pilot study on the effectiveness of a novel training for interprofessional primary care providers on the clinically significant issue of fear of cancer recurrence...
February 10, 2018: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29425724/skin-cancer-interventions-across-the-cancer-control-continuum-a-review-of-experimental-evidence-1-1-2000-6-30-2015-and-future-research-directions
#3
REVIEW
Alan C Geller, Barbra A Dickerman, Jennifer M Taber, Laura A Dwyer, Anne M Hartman, Frank M Perna
While the general efficacy of skin cancer interventions have been reviewed, employing the cancer control continuum would be useful to identify research gaps at specific cancer control points. We characterized the intervention evidence base for specific behavioral targets (e.g., tanning, sun protection, screening) and clinically related targets (e.g., sunburn, skin exams, cancers) at each point in the cancer control continuum. The review included articles published from 1/1/2000-6/30/15 that had an experimental design and targeted behavioral intervention in skin cancer (e...
February 6, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29419945/shared-mental-models-of-cancer-survivorship-care
#4
M C Hebdon, K Abrahamson, R R Griggs, S A McComb
Quality cancer survivorship care relies on care continuity within the healthcare team. The purpose of this study was to explore the perspectives of healthcare team members regarding cancer survivorship care using the framework of shared mental models. Semi-structured interviews of cancer survivors, primary support individuals, oncology providers, primary care providers and registered nurses were completed. Data were extrapolated to seven primary themes with associated secondary themes. Primary themes included survivor definition and identity, care setting, team member roles, care gaps, survivor needs, barriers to care and facilitators of care...
February 8, 2018: European Journal of Cancer Care
https://www.readbyqxmd.com/read/29409399/the-implications-of-women-s-activity-limitations-and-role-disruptions-during-breast-cancer-survivorship
#5
Sharon Keesing, Lorna Rosenwax, Beverley McNamara
Early survivorship is a time of critical transition for women survivors of breast cancer as they attempt to resume functional activities and important life roles. This study aimed to explore the challenges of women and their partners as they attempted to resume activities and roles, identify unmet needs and make recommendations regarding a suitable framework to support women and partners to recommence valued activities and important roles during early survivorship. Qualitative methods utilising in-depth interviews of women (n = 18) and their partners (n = 8), and two focus groups (n = 10) were completed in Perth, Western Australia, between June 2014 and April 2015...
January 2018: Women's Health
https://www.readbyqxmd.com/read/29396594/integrative-medicine-and-the-oncology-patient-options-and-benefits
#6
Karen Armstrong, Thomas Lanni, Maureen M Anderson, Gail Elliott Patricolo
Cancer is a major public health problem, and cancer patients and survivors face many physical and emotional challenges after the initial diagnosis, through treatment, and in the post-treatment period. Different integrative medicine (IM) modalities can be used to mitigate some of the physical issues that originate from the cancer itself or the treatment and to promote well-being and emotional health. Here, we discuss how an IM Department can function in a hospital system, particularly with regard to oncology patients, the modalities appropriate for oncology patients, how these modalities can benefit this patient population, and the role of IM in cancer survivorship...
February 2, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29396283/urological-survivorship-issues-among-adolescent-boys-and-young-men-who-are-cancer-survivors
#7
REVIEW
Troy Sukhu, Sherry Ross, R Matthew Coward
BACKGROUND: Urological survivorship issues encompass an area that may potentially be overlooked after treatment of childhood cancer in adolescent boys and young men. Side effects of cancer therapy may include subsequent development of erectile dysfunction (ED), hypogonadism, and infertility in adulthood. AIM: The purpose of this review is to focus on the etiology and prevalence of the range of sexual and gonadal dysfunction in adolescent boys and young men who are cancer survivors, while discussing current recommendations for evaluation and treatment...
January 27, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29395306/the-role-of-physical-activity-in-breast-and-gynecologic-cancer-survivorship
#8
REVIEW
Kathryn P Pennington, Anne McTiernan
Physical activity improves physical functioning, cancer-related symptoms, and quality of life in cancer survivors, and is beneficial across all phases of survivorship. Observational studies suggest that high levels of physical activity may also improve cancer outcomes such as survival, but randomized controlled trials of exercise interventions in oncology patients with survival outcomes as a primary endpoint are needed and ongoing. This review focuses on the role of physical activity in breast and gynecologic cancer survivorship, based on the available evidence...
January 27, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29378785/the-women-s-health-initiative-whi-life-and-longevity-after-cancer-lilac-study-description-and-baseline-characteristics-of-participants
#9
Electra D Paskett, Bette J Caan, Lisa Johnson, Brittany M Bernardo, Gregory S Young, Michael L Pennell, Roberta M Ray, Candyce H Kroenke, Peggy L Porter, Garnet L Anderson
Background: The Women's Health Initiative (WHI) Life and Longevity After Cancer (LILAC) study offers an important opportunity to advance cancer research by extending the original WHI studies to examine survivorship in women diagnosed with cancer during their participation in WHI.Methods: The goals of LILAC are to (i) obtain cancer treatment information and long-term cancer outcomes for women diagnosed with one of eight selected cancers (breast, endometrial, ovarian, lung, and colorectal cancers, and melanoma, lymphoma, and leukemia); (ii) augment the existing WHI biorepository with fixed tumor tissue from the solid tumor sites for cancers diagnosed since 2002; and (iii) develop, refine, and validate methods to use administrative data to capture treatment and recurrence data...
January 29, 2018: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29377985/cancer-therapy-induced-cardiomyopathy-can-human-induced-pluripotent-stem-cell-modelling-help-prevent-it
#10
Jonathan P Stack, Javid Moslehi, Nazish Sayed, Joseph C Wu
Cardiotoxic effects from cancer therapy are a major cause of morbidity during cancer treatment. Unexpected toxicity can occur during treatment and/or after completion of therapy, into the time of cancer survivorship. While older drugs such as anthracyclines have well-known cardiotoxic effects, newer drugs such as tyrosine kinase inhibitors, proteasome inhibitors, and immunotherapies also can cause diverse cardiovascular and metabolic complications. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are increasingly being used as instruments for disease modelling, drug discovery, and mechanistic toxicity studies...
January 25, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29372486/usability-and-acceptance-evaluation-of-aceso-a-web-based-breast-cancer-survivorship-tool
#11
Akshat Kapoor, Priya Nambisan
PURPOSE: The specific objective of this research is to design and develop a personalized Web application to support breast cancer survivors after treatment, as they deal with post-treatment challenges, such as comorbidities and side effects of treatment. METHODOLOGY: A mixed-methods approach, utilizing a combination of think-aloud analysis, personal interviews, and surveys, was adopted for user acceptance and usability testing among a group of breast cancer survivors...
January 25, 2018: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29367346/genetically-modified-lentiviruses-that-preserve-microvascular-function-protect-against-late-radiation-damage-in-normal-tissues
#12
Aadil A Khan, James T Paget, Martin McLaughlin, Joan N Kyula, Michelle J Wilkinson, Timothy Pencavel, David Mansfield, Victoria Roulstone, Rohit Seth, Martin Halle, Navita Somaiah, Jessica K R Boult, Simon P Robinson, Hardev S Pandha, Richard G Vile, Alan A Melcher, Paul A Harris, Kevin J Harrington
Improvements in cancer survival mean that long-term toxicities, which contribute to the morbidity of cancer survivorship, are being increasingly recognized. Late adverse effects (LAEs) in normal tissues after radiotherapy (RT) are characterized by vascular dysfunction and fibrosis causing volume loss and tissue contracture, for example, in the free flaps used for immediate breast reconstruction after mastectomy. We evaluated the efficacy of lentivirally delivered superoxide dismutase 2 (SOD2) overexpression and connective tissue growth factor (CTGF) knockdown by short hairpin RNA in reducing the severity of LAEs in an animal model of free flap LAEs...
January 24, 2018: Science Translational Medicine
https://www.readbyqxmd.com/read/29341969/pursuing-normality-reflections-on-cancer-survivorship-care-of-lymphoma-survivors
#13
Louise S Madsen, Charlotte Handberg
BACKGROUND: The present study explored the reflections on cancer survivorship care of lymphoma survivors in active treatment. Lymphoma survivors have survivorship care needs, yet their participation in cancer survivorship care programs is still reported as low. OBJECTIVE: The aim of this study was to understand the reflections on cancer survivorship care of lymphoma survivors to aid the future planning of cancer survivorship care and overcome barriers to participation...
January 16, 2018: Cancer Nursing
https://www.readbyqxmd.com/read/29339938/understanding-cancer-survivors-information-needs-and-information-seeking-behaviors-for-complementary-and-alternative-medicine-from-short-to-long-term-survival-a-mixed-methods-study
#14
Lou Ann Scarton, Guilherme Del Fiol, Ingrid Oakley-Girvan, Bryan Gibson, Robert Logan, T Elizabeth Workman
Objective: The research examined complementary and alternative medicine (CAM) information-seeking behaviors and preferences from short- to long-term cancer survival, including goals, motivations, and information sources. Methods: A mixed-methods approach was used with cancer survivors from the "Assessment of Patients' Experience with Cancer Care" 2004 cohort. Data collection included a mail survey and phone interviews using the critical incident technique (CIT)...
January 2018: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/29338610/cns-side-effects-of-immune-checkpoint-inhibitors-preclinical-models-genetics-and-multimodality-therapy
#15
Gwendolyn J McGinnis, Jacob Raber
Following cancer treatment, patients often report behavioral and cognitive changes. Novel cancer immunotherapeutics have the potential to produce sustained cancer survivorship, meaning patients will live longer with the side effects of treatment. Given the role of inflammatory pathways in mediating behavioral and cognitive impairments seen in cancer, we aim in this review to discuss emerging evidence for the contribution of immune checkpoint blockade to exacerbate these CNS effects. We discuss ongoing studies regarding the ability of immune checkpoint inhibitors to reach the brain and how treatment responses to checkpoint inhibitors may be modulated by genetic factors...
September 2017: Immunotherapy
https://www.readbyqxmd.com/read/29332134/breast-cancer-survivorship-state-of-the-science
#16
REVIEW
Kathy Pan, Arti Hurria, Rowan T Chlebowski
PURPOSE: Only recently has breast cancer survivorship earned formal recognition as a research discipline. Complicating survivorship research is the frequent overlap between aging and treatment sequelae. The ACS/ASCO 2016 Breast Cancer Survivorship Care Guideline (Guideline) reflects comprehensive literature review through April 2015, while the jointly sponsored, inaugural Cancer Survivorship Symposium in 2016 (Symposium) reflects ongoing research activity in the area. Together, these platforms provide an opportunity to examine the use of randomized trials and controlled studies in survivorship care research...
January 13, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29318512/health-status-of-older-cancer-survivors-results-of-the-polsenior-study
#17
Joanna Sulicka, Agnieszka Pac, Monika Puzianowska-Kuźnicka, Tomasz Zdrojewski, Jerzy Chudek, Beata Tobiasz-Adamczyk, Małgorzata Mossakowska, Anna Skalska, Andrzej Więcek, Tomasz Grodzicki
PURPOSE: The purpose of this study is to characterize health status of older cancer survivors using data from the population-based PolSenior study. METHODS: We compared cancer survivors and non-cancer subjects according to comorbidities, functional status, mental health, and sociodemographic factors. RESULTS: There were 286 (5.8%) cancer survivors in a population of 4943 adults aged 65 years and older. The mean age of cancer survivors was 79...
January 9, 2018: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29303476/are-cancer-survivors-following-the-national-comprehensive-cancer-network-health-behavior-guidelines-an-assessment-of-patients-attending-a-cancer-survivorship-clinic
#18
Kelly A Hyland, Jamie M Jacobs, Inga T Lennes, William F Pirl, Elyse R Park
PURPOSE: Engaging in positive health behaviors post-treatment is important for cancer survivors' health. However, little is known about whether survivors are practicing health promoting behaviors. We aimed to explore whether survivors are meeting the recent health behavior guidelines set forth by the National Comprehensive Cancer Network (NCCN) and to examine associations between health behaviors and distress. METHODS: Sixty-six survivors completed a cross-sectional questionnaire assessing health behaviors prior to an initial appointment at a survivorship care clinic...
January 2018: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/29288122/worse-urinary-sexual-and-bowel-function-cause-emotional-distress-and-vice-versa-in-men-treated-for-prostate-cancer
#19
Heather Orom, Caitlin Biddle, Willie Underwood, Christian J Nelson
PURPOSE: Definitive therapy for prostate cancer (e.g., surgery, radiotherapy) often has side effects, including urinary, sexual, and bowel dysfunction. The purpose of this study was to test whether urinary, sexual, and bowel function contribute to emotional distress during the first two years post treatment, and whether distress may, in turn, decrease function. MATERIALS AND METHODS: Participants were 1,148 men diagnosed with clinically localized disease who were treated with either surgery (63%) or radiotherapy (37%)...
December 26, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29282156/examining-cancer-survivorship-trajectories-exploring-the-intersection-between-qualitative-illness-narratives-and-quantitative-screening-instruments
#20
Chelsea Ratcliff, Aanand D Naik, Lindsey Ann Martin, Jennifer Moye
OBJECTIVE: This article examines the associations of quantitatively refined trajectories of adjustment to cancer survivorship determined by previously published qualitative narrative analysis. METHOD: Patients completed measures of cancer-related worry (Cancer Related Worries Scale), depression (Patient Health Questionnaire-9), posttraumatic growth (Benefit Finding Scale), and open-ended survey questions 6, 12, and 18 months postdiagnosis of head and neck, esophageal, gastric, or colorectal cancer...
December 28, 2017: Palliative & Supportive Care
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