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Drug eruption

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https://www.readbyqxmd.com/read/28925328/a-case-report-of-tadalafil-associated-fixed-drug-eruption
#1
Ada W Chiu, Robert Stenstrom
Tadalafil is a drug approved for use in erectile dysfunction, but increasingly being used recreationally. There have only been scant case reports on tadalafil causing fixed drug eruption (FDE). Patients who use tadalafil recreationally are less likely to seek medical attention and the diagnosis can often be missed, given the difficulty in diagnosis. However, clinical examination together with a detailed medication history can provide clinicians with good evidence of the association without invasive biopsies...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28914958/assessment-of-histopathological-features-of-maculopapular-viral-exanthem-and-drug-induced-exanthem
#2
Sanjay Singh, Sujay Khandpur, Sudheer Arava, Ramashankar Rath, M Ramam, Manoj Singh, Vinod K Sharma, S K Kabra
Maculopapular exanthem (MPE) is defined as a skin eruption consisting of macules and papules which does not form a scale. When associated with oral lesions, the term exanthem with 'enanthem' term is employed (1). Viral infection and drug reaction are the commonest causes of exanthem.
September 15, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28901812/efficacy-of-a-3c-like-protease-inhibitor-in-treating-various-forms-of-acquired-feline-infectious-peritonitis
#3
Niels C Pedersen, Yunjeong Kim, Hongwei Liu, Anushka C Galasiti Kankanamalage, Chrissy Eckstrand, William C Groutas, Michael Bannasch, Juliana M Meadows, Kyeong-Ok Chang
Objectives The safety and efficacy of the 3C-like protease inhibitor GC376 was tested on a cohort of client-owned cats with various forms of feline infectious peritonitis (FIP). Methods Twenty cats from 3.3-82 months of age (mean 10.4 months) with various forms of FIP were accepted into a field trial. Fourteen cats presented with wet or dry-to-wet FIP and six cats presented with dry FIP. GC376 was administered subcutaneously every 12 h at a dose of 15 mg/kg. Cats with neurologic signs were excluded from the study...
September 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28879222/multiple-fixed-drug-eruption-to-minocycline-at-sites-of-healed-burn-and-zoster-an-interesting-case-of-locus-minoris-resistentiae
#4
Renata Dalla Costa, Connie Yihan Yang, Molly Stout, Daniela Kroshinsky, Arianne Shadi Kourosh
No abstract text is available yet for this article.
September 2017: JAAD Case Reports
https://www.readbyqxmd.com/read/28878924/serpentine-supravenous-hyperpigmentation
#5
Indirakshi Jamalpur, Harikrishna Reddy Mogili, Abhilash Koratala
Serpentine supravenous hyperpigmentation is a peculiar cutaneous eruption that follows the path of vein after intravenous injection of the chemotherapeutic agent. The lesions gradually resolve spontaneously if administration of the offending agent is stopped through the affected limb. Drugs such as 5-fluorouracil, docetaxel, vinorelbine, hydroxychloroquine, fotemustine, and minocycline are implicated.
September 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28872202/fixed-drug-eruption-induced-by-ciprofloxacin-and-cross-reactivity-to-other-quinolones
#6
Diana R Garnica Velandia, Gaspar Dalmau Duch, Vanessa Gázquez García, Martina Indiveri, Pere Gaig Jané
No abstract text is available yet for this article.
October 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28872088/-clinical-characteristics-and-prognosis-for-126-patients-with-severe-drug-eruption
#7
Jie Li, Manyun Mao, Ni Tang, Rui Zhai, Wu Zhu, Mei Yi, Mingliang Chen
To explore the clinical characteristics of various types of severe drug eruption and common sensitized drugs, and to provide clinical references for reducing the incidence of severe drug eruption.
 Methods: The clinical data regarding 126 cases of severe drug eruption were analyzed retrospectively from June 2009 to May 2017 in Xiangya Hospital, Central South University.
 Results: In the 126 cases of severe drug eruption, the distribution of men and women ratio was 1:1.38. The length of stay was (12.7±9...
August 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28852258/olanzapine-induced-skin-eruptions
#8
Nishtha Chawla, Saurabh Kumar, Yatan Pal Singh Balhara
Adverse cutaneous reactions are known to occur with psychotropic medications, which may lead to poor drug compliance. As compared to other group of psychotropics, there is relatively scarce literature on olanzapine-induced skin eruptions. We present a case of a 39-year-old man diagnosed with first episode mania and alcohol dependence syndrome who was started on tablet olanzapine which leads to fixed drug eruptions. Exhaustive investigations were done, all of which came out within normal limits. A diagnosis of fixed drug eruptions was made by the dermatologist...
July 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28845181/neosensitization-to-multiple-drugs-following-valproate-induced-drug-reaction-with-eosinophilia-and-systemic-symptoms-syndrome
#9
Jae Min Song, Young Eun Jung, Joon Hyuk Park, Moon Doo Kim, Min Seok Cheon, Chang In Lee
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is associated with severe skin eruptions, fever, hematological abnormalities, and multi-organ involvement. Although aromatic anticonvulsant drugs have been frequently associated with the manifestation of DRESS syndrome, its induction following treatment with nonaromatic anticonvulsants, such as valproate, has rarely been reported. Moreover, there are limited data regarding the development of neosensitization related to chemically unrelated drugs following an episode of DRESS syndrome...
July 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28843624/sorafenib-stimulates-human-skin-type-mast-cell-degranulation-and-maturation
#10
Yukari Mizukami, Koji Sugawara, Yukimi Kira, Daisuke Tsuruta
BACKGROUND: Sorafenib is a multi-kinase inhibitor for treating advanced hepatocellular and renal cell carcinomas by targeting various types of receptors and signaling molecules, including vascular endothelial growth factor receptors, platelet-derived growth factor receptor, and Raf-1. Sorafenib may cause diverse cutaneous adverse reactions, including hand-foot reaction, facial and scalp eruptions, alopecia and pruritus. However, the mechanism of these adverse effects has not been well-investigated...
August 12, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28839396/nilotinib-induced-keratosis-pilaris-associated-with-alopecia-areata-and-eyebrow-thinning
#11
Maya Halabi Tawil, Rana El Khoury, Roland Tomb, Marwan Ghosn
Tyrosine kinase enzymes are an attractive target for anticancer therapies. Tyrosine kinase inhibitors (TKI) are well tolerated; somehow severe systemic side effects are rarely seen during treatment. Toxicities of skin and appendages may lead to poor compliance, psychosocial inconvenience, and drug interruption. Changes of the hair can arise following cures with TKI. Nilotinib, a second-generation TKI, has been responsible for various cutaneous side effects including different clinical presentations of alopecia (scarring and nonscarring forms)...
April 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28834062/generalized-pustular-drug-eruption-caused-by-topical-5-fluorouracil
#12
Kathleen M Nemer, Jason F Solus, Andras Schaffer, Ilana S Rosman, Sena J Lee
No abstract text is available yet for this article.
August 18, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28830901/drug-rash-with-eosinophilia-and-systemic-symptoms-dress-caused-by-phenytoin
#13
Muhammad Riaz, Bruce D Ragsdale, Zia Ur Rahman, Gaurav Nigam
Drug rash with eosinophilia and systemic symptoms (DRESS) is a rare but potentially life-threatening condition with high mortality. Diagnosis is challenging due to variable clinical presentation and a protracted latency period following initiation of the offending drug. DRESS is a complex interplay that starts by introduction of the offending drug, reactivation of viruses and activation of the immune system. Herpes virus reactivation is considered a diagnostic marker and indicator of illness severity. Prompt recognition and the removal of offending agent remain the key to successful treatment...
August 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28827990/amoxycillin-and-clavulanic-acid-induced-stevens-johnson-syndrome-a-case-report
#14
Maheen Zaidi, Syeda Kashaf Zaidi, Moomal Bhutto, Mohammad Yasir Umer
Stevens-Johnson syndrome (SJS) is an immune mediated hypersensitivity reaction. Significant involvement of oral, nasal, eye, vaginal, urethral, GI and lower respiratory tract mucous membrane may develop. It is usually a reaction due to a medication or due to an infection. In 95 % of case reports, drugs were found to be an important cause for the development of SJS. In this case report, a 32 year old female reported chief complaint of itch skin eruptions all over the body along with erosive lesions on tongue, lips, buccal mucosa and genital mucosa...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28811176/bullous-fixed-drug-eruption-secondary-to-chlorthalidone
#15
Nathaly Cuervo-Pardo, Aurora Gonzalez-Estrada, Lyda Cuervo-Pardo, Keerthi Reddy, Alexei Gonzalez-Estrada
No abstract text is available yet for this article.
August 12, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28809998/temporal-association-of-herpes-zoster-eruption-post-aminolevulinic-acid-hydrochloride-photodynamic-therapy-for-actinic-keratoses
#16
Katie Manno, Joel L Cohen
<p>Herpes zoster is a common and painful disease caused by the reactivation of the varicella-zoster virus with a higher incidence and severity associated with increasing age as well as compromised immune status. Acute inciting events for this eruption are not always known, but can include illness, stress, and mechanical injury. Photodynamic therapy (PDT) is a widely used treatment modality for precancerous skin lesions that has not been previously associated with provoking a herpes zoster outbreak. We present a case of herpes zoster eruption occurring after PDT for actinic keratoses in a patient with Non-Hodgkin Lymphoma (NHL)...
August 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28768672/an-illusion-of-septic-shock-acute-generalised-exanthematous-pustulosis-with-multiorgan-dysfunction
#17
Manisha Jakkidi, Carine Basmadjian, Satyajeet Roy
Acute generalised exanthematous pustulosis (AGEP) is a rare cutaneous eruption, most often caused by commonly used antibiotics. It is characterised by an acute onset of non-follicular sterile pustular rash and erythema within hours or days of drug exposure and usually resolves spontaneously within 1-2 weeks once the drug is discontinued. Haemodynamic involvement in the form of shock is rare. Here, we present a severe case of AGEP, manifesting with systemic involvement and haemodynamic instability resulting in shock with multiorgan dysfunction...
August 2, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28761848/fixed-drug-eruption-induced-by-levocetirizine
#18
Isa An, Vasfiye Demir, Ibrahim Ibiloglu, Sedat Akdeniz
No abstract text is available yet for this article.
July 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28761298/three-cases-of-autoimmune-progesterone-dermatitis
#19
Hye Rin You, Sook Jung Yun, Sung Jin Kim, Seung-Chul Lee, Young Ho Won, Jee-Bum Lee
Autoimmune progesterone dermatitis is a rare cyclic premenstrual reaction to progesterone produced during the luteal phase of the menstrual cycle. The clinical symptoms of autoimmune progesterone dermatitis overlap with other forms of dermatosis such as erythema multiforme, eczema, fixed drug eruption, urticaria, and angioedema. We experienced 3 cases of autoimmune progesterone dermatitis. All patients had a recurrent history of monthly skin eruptions. Skin lesions normally began a few days before menstruation and resolved a few days later...
August 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28744306/prevalence-and-clinical-profile-of-drug-eruptions-among-antiretroviral-therapy-exposed-hiv-infected-people-in-yaound%C3%A3-cameroon
#20
Emmanuel Armand Kouotou, Jobert Richie Nansseu, Vanessa Nancy Ngono, Sandra A Tatah, Anne Cecile Zoung-Kanyi Bissek, Elie Claude Ndjitoyap Ndam
BACKGROUND: Prevalence and incidence of drug eruptions vary around the world and are influenced by some key factors including HIV infection. OBJECTIVE: This study aimed to find the peculiarities of drug eruptions in people living with HIV (PLHIV) and on antiretroviral therapy (ART). METHODS: This was a retrospective cross-sectional study including ART-taking PLHIV, aged 15+ years, followed up between January 2010 and December 2014 at the day-care unit of the Yaoundé Central Hospital, and who presented with drug eruptions after ART initiation...
2017: Dermatology Research and Practice
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