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https://www.readbyqxmd.com/read/29766517/occupational-fixed-drug-eruption-with-ipe-wood
#1
Quentin Landry, Jean-Luc Bourrain, Nadia Raison-Peyron, Olivier Dereure, Aurélie Du-Thanh
No abstract text is available yet for this article.
May 15, 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29765217/allergy-to-chlorpromazine-and-valproic-acid-following-carbamazepine-hypersensitivity-in-a-patient-with-an-hla-b-4601-allele
#2
Kumi Sakurada, Takeshi Kozaru, Kazuo Yamada, Masashi Nibuya, Kiyoshi Nagata, Eiji Suzuki
A 73-year-old man, exhibiting psychomotor excitement after traumatic brain injury, developed allergic cutaneous eruptions and hepatic inflammation that did not resolve after the cessation of carbamazepine (CBZ). Fusing maculopapular erythema was observed in the face, neck, presternal region, and bilaterally in the forearms and feet. A drug-induced lymphocyte stimulation test revealed hypersensitivity to chlorpromazine (CPZ) and valproic acid (VPA), as well as to CBZ. The allergic reaction with eosinophilia to CPZ and VPA was suspected to have emerged following CBZ hypersensitivity, since previous treatment with CPZ and VPA prior to the introduction of CBZ had not been associated with adverse reactions earlier in the course of treatment...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29763476/drug-induced-linear-iga-bullous-dermatosis-in-a-patient-with-a-vancomycin-impregnated-cement-spacer
#3
Kelsie Riemenschneider, Daren A Diiorio, John A Zic, Matthew R Livingood, Jo-David Fine, Jennifer G Powers, Jeffrey P Zwerner, Eric Tkaczyk
Linear IgA bullous dermatosis (LABD) is an autoimmune blistering rash caused by IgA autoantibodies against the epidermal basement membrane zone. It commonly is drug induced, often in association with systemic vancomycin. We report a case of a previously healthy 77-year-old man who developed a diffuse macular rash and hemorrhagic bullae on the left leg 10 days after placement of a vancomycin-impregnated cement spacer (VICS) during a revision knee arthroplasty and initiation of postoperative treatment with intravenous (IV) vancomycin...
April 2018: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29756000/bullous-fixed-drug-eruption-following-ibuprofen-ingestion
#4
Seyed Amirhossein Fazeli, Morteza Abbasi, Hadi Jalali, Sonia Eskandari, Farzaneh Shamshirgaran, Zahra Dehghani, Reza Golabchifard, Shahram Ghiyasvand, Kaveh Ghannad
Fixed drug eruption (FDE) is a drug reaction involving skin and less commonly mucosal membranes. The common manifestation is localized well-demarcated patches or plaques appeared following receiving of a culprit drug. When re-exposure occurs, the rashes will appear at areas involved in previous episodes. Limited reports on bullous FDE due to ibuprofen have been documented before. Herein, we described an elderly man who experienced multifocal lesions in his oral mucosa, penis, and multiple sites of skin following ibuprofen ingestion confirmed as FDE by pathological studies...
January 2018: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29754885/langerhans-cell-histiocytosis-in-children-history-classification-pathobiology-clinical-manifestations-and-prognosis
#5
REVIEW
Jolie Krooks, Milen Minkov, Angela G Weatherall
Langerhans cell histiocytosis (LCH) is an inflammatory neoplasia of myeloid precursor cells driven by mutations in the mitogen-activated protein kinase pathway. When disease involves the skin, LCH most commonly presents as a seborrheic dermatitis or eczematous eruption on the scalp and trunk. Evaluation for involvement of other organ systems is essential, because 9 of 10 patients presenting with cutaneous disease also have multisystem involvement. Clinical manifestations range from isolated disease with spontaneous resolution to life-threatening multisystem disease...
June 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29726858/photo-rounds-generalized-pustular-eruption
#6
Stanislav N Tolkachjov, David A Wetter, Benjamin J Sandefur
The timing of a recent prescription for azithromycin and the morphology of this eruption made us suspect a drug reaction. But which type of reaction were we looking at?
May 2018: Journal of Family Practice
https://www.readbyqxmd.com/read/29703869/a-10-years-retrospective-study-on-severe-cutaneous-adverse-reactions-scars-in-a-tertiary-hospital-in-penang-malaysia
#7
C H Loo, W C Tan, Y H Khor, L C Chan
INTRODUCTION: Severe cutaneous adverse drug reactions (SCARs) are not uncommon and potentially lifethreatening. Our objective is to study the patient characteristics, the pattern of implicated drugs and treatment outcome among patients with SCARs. METHODS: A 10-year retrospective analysis of SCARs cases in Penang General Hospital was carried out from January 2006 to December 2015. Data collection is based on the Malaysian Adverse Drug Reactions Advisory Committee registry and dermatology clinic records...
April 2018: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/29699022/-an-intramuscular-injection-of-sodium-dimer-captopropane-sulfonate-induced-epidermal-necrolysis-type-drug-eruption-in-1-case
#8
Y L Gao
No abstract text is available yet for this article.
February 20, 2018: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/29697423/using-stratum-corneum-thickness-and-configuration-to-distinguish-lichenoid-dermatoses
#9
Amanda F Marsch
BACKGROUND: Clues in the stratum corneum (SC) can aide in histopathologic diagnosis of many conditions. OBJECTIVE: To determine if SC configuration and thickness could help differentiate the lichenoid dermatoses. METHODS: A retrospective study was performed. A total of 305 cases (55 lichenoid keratosis, 51 lichen planus, 7 hypertrophic lichen planus, 40 lichenoid drug eruption, 19 lichenoid graft-vs.-host disease, 14 hypertrophic lupus, 46 lichenoid actinic keratosis, 73 lentigo maligna) fulfilled the selection criteria...
April 24, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29690993/-drug-eruption
#10
Ali Tareen, Anette Bygum
Drug eruption is defined as an adverse cutaneous eruption secondary to drug intake. The most frequent variation is a morbilliform exanthema, although the clinical presentations may vary widely. The diagnosis is clinical, why thorough medical history and assessment are essential for the risk stratification of possible adverse cutaneous reaction. In Western hospitals, the prevalence is estimated to be 2-3% of the patients. Identification of the condition is therefore important for all healthcare professionals...
April 16, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29687065/giant-annular-lichenoid-drug-eruption-caused-by-efavirenz-therapy
#11
Emily Baumrin, Anisa Mosam, Ncoza C Dlova
No abstract text is available yet for this article.
April 2018: JAAD Case Reports
https://www.readbyqxmd.com/read/29630150/a-possible-role-for-dupilumab-dupixent-in-the-management-of-idiopathic-chronic-eczematous-eruption-of-aging
#12
Grace C Brummer, Lawrence T Wang, Richard D Sontheimer
Aging individuals can develop generalized, exquisitely-pruritic, eczematous eruptions of uncertain etiology that can be therapeutically-refractory and life-altering. Limited information exists in the literature to guide clinicians in the diagnosis and management of such patients. It is suggested that in approximately 40% of such patients a known cause for their chronic pruritic eruptions cannot be identified. In this report we will refer to this subgroup of patients as having idiopathic chronic eczematous eruption of aging (CEEA)...
February 15, 2018: Dermatology Online Journal
https://www.readbyqxmd.com/read/29619062/immediate-type-hypersensitivity-and-late-phase-reaction-occurred-consecutively-in-a-patient-receiving-ethambutol-and-levofloxacin
#13
Yukihiko Kato, Yu Sato, Miho Nakasu, Ryoji Tsuboi
Background: We experienced a rare case of immediate type hypersensitivity and late phase reaction to anti-tubercular therapy consisting of ethambutol and levofloxacin, which occurred in close succession, giving the appearance of a single, continuous reaction to one drug. Case presentation: The patient was a man in his 70's who began therapy consisting of isoniazide, rifampicin, and ethambutol for pulmonary tuberculosis. Since the patient had a drug eruption within several hours after the start of his treatment, his reaction to ethambutol was assessed first among the three suspected drugs using an oral challenge test...
2018: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/29614487/prevalence-of-hypersensitivity-reactions-in-children-associated-with-acetaminophen-a-systematic-review-and-meta-analysis
#14
Sofianne Gabrielli, Alexandra Langlois, Moshe Ben-Shoshan
BACKGROUND: Acetaminophen is the most commonly used antipyretic in children. However, there are limited data assessing hypersensitivity reactions related to acetaminophen usage. OBJECTIVES: To conduct a systematic review to characterize reported reactions to acetaminophen in adults and children, and perform a meta-analysis to assess the prevalence of acetaminophen hypersensitivity in children with a suspected acetaminophen allergy. METHODS: We performed a systematic review of studies reporting hypersensitivity reactions to acetaminophen by searching 2 electronic databases...
April 3, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29610831/association-of-hla-a-31-01-screening-with-the-incidence-of-carbamazepine-induced-cutaneous-adverse-reactions-in-a-japanese-population
#15
Taisei Mushiroda, Yukitoshi Takahashi, Teiichi Onuma, Yoshiaki Yamamoto, Tetsumasa Kamei, Tohru Hoshida, Katsuya Takeuchi, Kotaro Otsuka, Mitsutoshi Okazaki, Masako Watanabe, Kosuke Kanemoto, Tomohiro Oshima, Atsushi Watanabe, Shiro Minami, Kayoko Saito, Hisashi Tanii, Yasushi Shimo, Minoru Hara, Shinji Saitoh, Toshihiko Kinoshita, Masaki Kato, Naoto Yamada, Naoki Akamatsu, Toshihiko Fukuchi, Shigenobu Ishida, Shingo Yasumoto, Atsushi Takahashi, Takeshi Ozeki, Takahisa Furuta, Yoshiro Saito, Nobuyuki Izumida, Yoko Kano, Tetsuo Shiohara, Michiaki Kubo
Importance: Carbamazepine, a commonly used antiepileptic drug, is one of the most common causes of cutaneous adverse drug reactions (cADRs) worldwide. The allele HLA-A*31:01 is reportedly associated with carbamazepine-induced cADRs in Japanese and European populations; however, the clinical utility of HLA-A*31:01 has not been evaluated. Objective: To assess the use of HLA-A*31:01 genetic screening to identify Japanese individuals at risk of carbamazepine-induced cADRs...
April 2, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29601624/psoriasiform-pemphigus-foliaceus-in-an-african-american-female-an-important-clinical-manifestation
#16
Evan Austin, Jillian W Millsop, Haines Ely, Jared Jagdeo, Joshua M Schulman
A 50-year-old African-American woman presented to the dermatology clinic with a pruritic eruption of 3 years' duration. On clinical examination, the patient had well-demarcated, pink, atrophic plaques and superficial erosions over the inframammary folds and mid-chest. She also had well-demarcated, hyperpigmented, hyperkeratotic scaly plaques over the abdomen, suprapubic region, elbows, knees, and back with sporadic small superficial blisters. A punch biopsy of the right abdomen was performed and revealed psoriasiform epidermal hyperplasia, focal parakeratosis, and acantholysis throughout the superficial spinous and granular layers...
April 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29590497/chronic-idiopathic-erythroderma-of-elderly-men-is-an-independent-entity-that-has-a-distinct-tarc-ige-profile-from-adult-atopic-dermatitis
#17
Yasunori Ohga, Bolortuya Bayaraa, Shinichi Imafuku
BACKGROUND: Although there are several diseases that cause erythroderma, patients are often encountered with erythroderma of unknown cause which persists for a long time. The aim of this study was to characterize this chronic idiopathic erythroderma (CIE). METHODS: Adult patients with CIE, atopic dermatitis (AD), psoriatic erythroderma (PsE), or generalized drug eruption (DE), who visited Fukuoka University Hospital Dermatology Department from 2010 to 2015, were enrolled...
March 28, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29581602/ismp-adverse-drug-reactions-minocycline-induced-drug-fever-without-skin-rash-lupus-erythematosus-like-eruption-induced-by-hydroxyurea-cardiotoxicity-and-fever-induced-by-clozapine-denosumab-induced-hepatotoxicity-severe-cardiotoxicity-induced-by-bevacizumab
#18
https://www.readbyqxmd.com/read/29574562/severe-cutaneous-adverse-drug-reactions-presentation-risk-factors-and-management
#19
REVIEW
S Shahzad Mustafa, David Ostrov, Daniel Yerly
PURPOSE OF STUDY: Immune-mediated adverse drug reactions occur commonly in clinical practice and include mild, self-limited cutaneous eruptions, IgE-mediated hypersensitivity, and severe cutaneous adverse drug reactions (SCAR). SCARs represent an uncommon but potentially life-threatening form of delayed T cell-mediated reaction. The spectrum of illness ranges from acute generalized exanthematous pustulosis (AGEP) to drug reaction with eosinophilia with systemic symptoms (DRESS), to the most severe form of illness, Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)...
March 24, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29569759/a-breath-taking-dress-due-to-amoxicillin-clavulanate-presenting-as-polymorphic-eruption-of-the-pregnancy
#20
M S van Kester, T J C Langeveld, H Bouwsma, J B van Rees, E R Holman, Y K O Teng, E J van Zuuren
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a delayed-type drug hypersensitivity reaction with potential life-threatening complications. To our knowledge, DRESS has never been described in pregnancy. Here, we report on a pregnant woman presenting with erythematous plaques on the abdomen, developing cardiac tamponade due to eosinophilic perimyocarditis and an interstitial pneumonitis five weeks after exposure to amoxicillin-clavulanate. This article is protected by copyright. All rights reserved...
March 23, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
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