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Maria Salvina Signorelli, Federico Nalis, Mariacatena Battiato, Eugenio Aguglia
The use of treatment with antipsychotic drugs highlights the difficulty of finding the right balance between the benefit on psychotic symptoms and the risk of the occurrence of adverse reactions. There is a strong genetic and pharmacological evidence supporting the hypothesis that activation of D2 receptors could lead to hypothermia and that the treatment haloperidol is capable of inducing hypothermia apomorfino similarily in laboratory animals. It also seems that, haloperidol is not the only antipsychotic able to determine this type of reaction, as some evidence suggests that other drugs such as reserpine, chlorpromazine would be capable of inducing hypothermia...
September 19, 2013: BMJ Case Reports
Mircea Beuran, Florin-Mihail Iordache
The following article, submitted in two complementary parts deals with an important and also modern concept developed under the name of damage-control surgery. Physiopathologically, the multiple injured patient is characterised by the probable, not just possible, appearance of the "blood's vicious cycle" of hypocoagulability, hypothermia and acidosis with death as a result. The first part of the article addresses the changes that are the reasons and the basis for applying damage-control surgery. Hypothermia is a direct result of trauma and patient's exposure to it but can also emerge throughout transportation, evaluation, emergency and surgical procedures to which the patient undergoes...
April 2008: Journal of Medicine and Life
N I Perepelkina, L N Markevich, D A Ignat'ev, L A Fialkovskaia, I K Kolomiĭtseva
Lipid content of tissue and of fraction of microsomes in neocortex of Wistar rats was studies under artificial hypothermia, after X-ray irradiation in dose 8 Gy under conditions of normothermia and artificial hypothermia in 48 h. The condition of artificial hypothermia get by cooling of rats to 15-18 degrees C. It was shown, that in fraction of microsomes of hypothermia rats the content of phosphatidylinositol was decreased, and in 48 h after cooling of rats the amount of protein, total and individual phospholipids was increased...
January 2008: Radiatsionnaia Biologiia, Radioecologiia
Ricardo Ribeiro Dias, Isaac Azevedo Silva, Alfredo Inácio Fiorelli, Noedir Antonio Groppo Stolf
Brain perfusion for adequate cerebral protection has changed over the years. The limitations of the time during total circulatory arrest with deep hypotermia, the inefficient cerebral metabolism during retrograde perfusion and special care to prevent cerebral embolism during antegrade perfusion have resulted in the development of different methods of cerebral protection during the evolution of aortic arch operations. Antegrade cerebral perfusion associated with moderate hypothermia is today, considered the best option for cerebral protection...
April 2007: Revista Brasileira de Cirurgia Cardiovascular
No abstract text is available yet for this article.
November 1957: A.M.A. Archives of Surgery
O Akça, D I Sessler
Perioperative hypotermia is a common, but preventable complication of anaesthesia and surgery. Mild perioperative hypothermia increases the incidence of morbid myocardial outcomes, reduces resistance to surgical wound infections, and prolongs both postanaesthetic recovery and hospitalization. Hypotermia causes a coagulopathy due to inhibition of platelet function. In this short review, we will discuss three studies done in the last 6 years, which explored the influence of perioperative hypotermia and blood loss...
April 2002: Minerva Anestesiologica
L Di Tommaso, M Caputo, R Ascione, G Janelli, V De Amicis, N Spampinato
Carotid endarterectomy (CEA) and myocardial revascularization can be performed in a single procedure, performing CEA before or during cardio-pulmonary by-pass (CPB), or using a double stage approach. Over a 4 year period, 17 patients underwent CEA and coronary artery by-pass (CAB) with a single stage procedure. Fourteen patients (82.3%) were male, 3 (17.6%) were female. The mean age was 66.3 +/- 7.07. One patient (5.8%) had a previous neurological event (stroke); 5 patients (29.4%) had a previous transient ischemic attacks (TIA)...
November 1995: Minerva Cardioangiologica
C Esperanza, R Gallardo
No abstract text is available yet for this article.
May 1968: Archivos del Instituto de Cardiología de México
D H Burke, J C Brooks
Body temperature depression was noted in rats, mice, and hamsters following intraperitoneal cobaltous chloride administration (25 mg/kg). Intracerebral cobalt injection elicited hypotermia in rats and mice but not in hamsters. Body temperature depression appeared to be centrally mediated in rats and mice and peripherally mediated in hamsters. The effect of intraperitoneal and intracerebral pretreatment with phentolamine, diphenhydramine, propranolol, cimetidine, and naloxone on the mouse rectal temperature response to cobalt (25 mg/kg ip) was noted...
June 1979: Journal of Pharmaceutical Sciences
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