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https://www.readbyqxmd.com/read/29245147/levels-of-trace-elements-methylmercury-and-polybrominated-diphenyl-ethers-in-foraging-green-turtles-in-the-south-china-region-and-their-conservation-implications
#1
Connie Ka Yan Ng, James Chung Wah Lam, Xiao Hua Zhang, He Xiang Gu, Tsung Hsien Li, Min Bin Ye, Zhong Rong Xia, Fei Yan Zhang, Jin Xia Duan, Wen Xiong Wang, Isaac Kam Sum Lam, George H Balazs, Paul K S Lam, Margaret B Murphy
Sea turtles are globally endangered and face daily anthropogenic threats, including pollution. However, there is a lack of ecotoxicological information on sea turtles, especially in the Asia-Pacific region. This study aims to determine pollutant levels of foraging green turtles (Chelonia mydas) in South China, including Hong Kong, Guangdong and Taiwan, as a basis for their conservation. Scute, liver and muscle tissues of stranded green turtles were analysed for levels of 17 trace elements and methylmercury (MeHg) (n = 86 for scute and n = 14 for liver) and polybrominated diphenyl ethers (PBDEs) (n = 11 for muscle and n = 13 for liver)...
December 12, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29245111/community-based-rehabilitation-offers-cost-effective-epilepsy-treatment-in-rural-guinea-bissau
#2
Eric van Diessen, Frank van der Maas, Vladimir Cabral, Willem M Otte
Treatment of epilepsy in low-income countries is a challenge considering the lack of resources, availability of antiepileptic drugs, and cultural beliefs. We used a community-based rehabilitation (CBR) service for the detection, monitoring, and treatment of epilepsy. A local network of trained community volunteers provided education, good quality antiepileptic drugs, and clinical follow-up for people with epilepsy (PWE). In a period of 2years, approximately 22,500 people were screened in central Guinea-Bissau, and 112 PWE were identified and registered...
December 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29245046/physiological-and-self-report-responses-of-parents-of-children-with-autism-spectrum-disorder-to-children-crying
#3
Yagmur Ozturk, Andrea Bizzego, Gianluca Esposito, Cesare Furlanello, Paola Venuti
Little is known about the physiological response of parents of children with Autism Spectrum Disorder (ASD) to crying of children who have already received the diagnosis of ASD. This study aimed to compare cardiac dynamics via Inter-Beat Interval (IBI) and self-reported emotional states of parents of children with ASD and of parents with typically developing (TD) children while listening to crying of children with ASD (ASD cry) and of typically developing children (TD cry). Analyses revealed higher IBI in parents of children with ASD than IBI in parents of TD children while listening to both cry groups; however no differences on self-reported emotional states were observed...
December 12, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29244965/management-of-chronic-diabetic-foot-ulcers-using-platelet-rich-plasma
#4
V Babaei, H Afradi, H Z Gohardani, F Nasseri, M Azarafza, S Teimourian
OBJECTIVE: Platelet-rich plasma (PRP) has been proposed as an adjunct for the treatment of foot ulcers in patients with diabetes, as well as a treatment for chronic and acute wounds. This study examined the application of PRP in the treatment of diabetic foot ulcers (DFUs) in patients. METHODS: This prospective study was conducted between 2011 and 2014. We used PRP, produced by a kit, for the treatment of DFUs. Patients were allocated to one of three groups, according to size of ulcer...
December 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/29244947/a-new-strategy-for-in-vitro-determination-of-carbonic-anhydrase-activity-from-analysis-of-oxygen-18-isotopes-of-co2
#5
Chiranjit Ghosh, Santanu Mandal, Mithun Pal, Manik Pradhan
The oxygen-18 isotopic (18O) composition in CO2 provides important insight into the variation of rate in isotopic fractionation reaction regulated by carbonic anydrase (CA) metalloenzyme. This work aims to employ 18O-isotope ratio-based analytical method for quantitative estimation of CA activity in erythrocytes for clinical testing purposes. Here, a new method has been developed that contains the measurements of 18O/16Oisotope ratios during oxygen-18 isotopic exchange between 12C16O16O and H218O of in-vitro biochemical reaction controlled by erythrocytes CA and estimation of enzymatic activity of CA from the isotopic composition of CO2...
December 15, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29244946/in-situ-synthetic-functionalization-of-a-transmembrane-protein-nanopore
#6
Stefan Borsley, Scott L Cockroft
Monitoring current flow through a single nanopore has proved to be a powerful technique for the in situ detection of molecular structure, binding and reactivity. Transmembrane proteins, such as α-hemolysin, provide particularly attractive platforms for nanopore sensing applications due to their atomically precise structures. However, many nanopore applications require the introduction of functional groups to tune selectivity. To date, such modifications have required genetic modification of the protein prior to functionalization...
December 15, 2017: ACS Nano
https://www.readbyqxmd.com/read/29244876/water-quality-assessment-of-australian-ports-using-water-quality-evaluation-indices
#7
Sayka Jahan, Vladimir Strezov
Australian ports serve diverse and extensive activities, such as shipping, tourism and fisheries, which may all impact the quality of port water. In this work water quality monitoring at different ports using a range of water quality evaluation indices was applied to assess the port water quality. Seawater samples at 30 stations in the year 2016-2017 from six ports in NSW, Australia, namely Port Jackson, Botany, Kembla, Newcastle, Yamba and Eden, were investigated to determine the physicochemical and biological variables that affect the port water quality...
2017: PloS One
https://www.readbyqxmd.com/read/29244842/intensive-care-treatments-associated-with-favorable-discharge-outcomes-in-argentine-children-with-severe-traumatic-brain-injury-for-the-south-american-guideline-adherence-group
#8
Monica S Vavilala, Silvia B Lujan, Qian Qiu, Michael J Bell, Nicolás M Ballarini, Nahuel Guadagnoli, María Alejandra Depetris, Gabriela A Faguaga, Gloria M Baggio, Leonardo O Busso, Mirta E García, Osvaldo R González Carrillo, Paula L Medici, Silvia S Sáenz, Elida E Vanella, Carly K Farr, Gustavo J Petroni
OBJECTIVE: Little is known about the critical care management of children with traumatic brain injury (TBI) in low middle income countries. We aimed to identify indicators of intensive care unit (ICU) treatments associated with favorable outcomes in Argentine children with severe TBI. METHODS: We conducted a secondary analysis of data from patients previously enrolled in a prospective seven center study of children with severe TBI who were admitted to an ICU in one of the seven study centers...
2017: PloS One
https://www.readbyqxmd.com/read/29244809/hiv-1-viraemia-and-drug-resistance-amongst-female-sex-workers-in-soweto-south-africa-a-cross-sectional-study
#9
Jenny Coetzee, Gillian Hunt, Maya Jaffer, Kennedy Otwombe, Lesley Scott, Asiashu Bongwe, Johanna Ledwaba, Sephonono Molema, Rachel Jewkes, Glenda E Gray
BACKGROUND: HIV drug resistance (HIVDR) poses a threat to future antiretroviral therapy success. Monitoring HIVDR patterns is of particular importance in populations such as sex workers (SWs), where documented HIV prevalence is between 34-89%, and in countries with limited therapeutic options. Currently in South Africa, there is a dearth in evidence and no ongoing surveillance of HIVDR amongst sex work populations. This study aims to describe the prevalence of HIVDR amongst a sample of female sex workers (FSWs) from Soweto, South Africa...
2017: PloS One
https://www.readbyqxmd.com/read/29244803/changes-in-brain-morphology-and-microstructure-in-relation-to-early-brain-activity-in-extremely-preterm-infants
#10
Maria Luisa Tataranno, Nathalie H P Claessens, Pim Moeskops, Mona C Toet, Karina J Kersbergen, Giuseppe Buonocore, Ivana Išgum, Alexander Leemans, Serena Counsell, Floris Groenendaal, Linda S de Vries, Manon J N L Benders
OBJECTIVE: To investigate the relation of early brain activity with structural (growth of the cortex and cerebellum) and white matter microstructural brain development. METHODS: 33 preterm neonates (gestational age 26±1 weeks) without major brain abnormalities were continuously monitored with electroencephalography (EEG) during the first 48 h of life. Rate of spontaneous activity transients per minute (SAT rate) and interSAT interval (ISI) in seconds per minute were calculated...
December 15, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29244783/using-a-commonly-down-regulated-cytomegalovirus-cmv-promoter-for-high-level-expression-of-ectopic-gene-in-a-human-b-lymphoma-cell-line
#11
Xiaojun Yu, Wei Geng, Hongchuan Zhao, Guobin Wang, Yijun Zhao, Zhe Zhu, Xiaoping Geng
BACKGROUND Vectors are widely used to drive gene expression using a promoter. However, not all promoters are able to drive ectopic gene expression efficiently, including CMV promoter. Here, we report our data using CMV promoter for high-level gene expression in a B lymphoma cell line DG75. MATERIAL AND METHODS A plasmid (pcDNA3.1(+)) containing the CD21 gene driven under CMV promoter was constructed. The plasmid was stably transfected into a human B lymphoma cell line DG75 for cellular surface CD21 expression, and flow cytometry was used to monitor CD21 expression...
December 15, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29244770/a-highly-sensitive-two-dimensional-inclinometer-based-on-two-etched-chirped-fiber-grating-arrays
#12
Hung-Ying Chang, Yu-Chung Chang, Wen-Fung Liu
We present a novel two-dimensional fiber-optic inclinometer with high sensitivity by crisscrossing two etched chirped fiber Bragg gratings (CFBG) arrays. Each array is composed of two symmetrically-arranged CFBGs. By etching away most of the claddings of the CFBGs to expose the evanescent wave, the reflection spectra are highly sensitive to the surrounding index change. When we immerse only part of the CFBG in liquid, the effective index difference induces a superposition peak in the refection spectrum. By interrogating the peak wavelengths of the CFBGs, we can deduce the tilt angle and direction simultaneously...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244756/recent-progress-in-biosensors-for-environmental-monitoring-a-review
#13
REVIEW
Celine I L Justino, Armando C Duarte, Teresa A P Rocha-Santos
The environmental monitoring has been one of the priorities at the European and global scale due to the close relationship between the environmental pollution and the human health/socioeconomic development. In this field, the biosensors have been widely employed as cost-effective, fast, in situ, and real-time analytical techniques. The need of portable, rapid, and smart biosensing devices explains the recent development of biosensors with new transduction materials, obtained from nanotechnology, and for multiplexed pollutant detection, involving multidisciplinary experts...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244738/design-of-an-air-pollution-monitoring-campaign-in-beijing-for-application-to-cohort-health-studies
#14
REVIEW
Sverre Vedal, Bin Han, Jia Xu, Adam Szpiro, Zhipeng Bai
No cohort studies in China on the health effects of long-term air pollution exposure have employed exposure estimates at the fine spatial scales desirable for cohort studies with individual-level health outcome data. Here we assess an array of modern air pollution exposure estimation approaches for assigning within-city exposure estimates in Beijing for individual pollutants and pollutant sources to individual members of a cohort. Issues considered in selecting specific monitoring data or new monitoring campaigns include: needed spatial resolution, exposure measurement error and its impact on health effect estimates, spatial alignment and compatibility with the cohort, and feasibility and expense...
December 15, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29244732/middleware-for-plug-and-play-integration-of-heterogeneous-sensor-resources-into-the-sensor-web
#15
Enoc Martínez, Daniel M Toma, Simon Jirka, Joaquín Del Río
The study of global phenomena requires the combination of a considerable amount of data coming from different sources, acquired by different observation platforms and managed by institutions working in different scientific fields. Merging this data to provide extensive and complete data sets to monitor the long-term, global changes of our oceans is a major challenge. The data acquisition and data archival procedures usually vary significantly depending on the acquisition platform. This lack of standardization ultimately leads to information silos, preventing the data to be effectively shared across different scientific communities...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244722/fault-diagnosis-of-internal-combustion-engine-valve-clearance-using-the-impact-commencement-detection-method
#16
Zhinong Jiang, Zhiwei Mao, Zijia Wang, Jinjie Zhang
Internal combustion engines (ICEs) are widely used in many important fields. The valve train clearance of an ICE usually exceeds the normal value due to wear or faulty adjustment. This work aims at diagnosing the valve clearance fault based on the vibration signals measured on the engine cylinder heads. The non-stationarity of the ICE operating condition makes it difficult to obtain the nominal baseline, which is always an awkward problem for fault diagnosis. This paper overcomes the problem by inspecting the timing of valve closing impacts, of which the referenced baseline can be obtained by referencing design parameters rather than extraction during healthy conditions...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244720/functional-imaging-with-18f-fdg-pet-ct-and-diffusion-weighted-imaging-dwi-in-early-response-evaluation-of-combination-therapy-of-elotuzumab-lenalidomide-and-dexamethasone-in-a-relapsed-multiple-myeloma-patient
#17
Christos Sachpekidis, Antonia Dimitrakopoulou-Strauss, Stefan Delorme, Hartmut Goldschmidt
Elotuzumab is the first monoclonal antibody approved for the treatment of relapsed-refractory multiple myeloma (MM) in combination with lenalidomide, an immunodulatory drug, and dexamethasone. We report on a multiply pre-treated MM patient with disease progression due to appearance of new focal lesions on imaging modalities, who was started on a combination treatment of elotuzumab, lenalidomide, and dexamethasone. After completion of three cycles of the new therapy the patient responded very well with a major decline of serological myeloma activity parameters serum monoclonal protein, kappa light chains, free light chains (FLC) ratio...
December 15, 2017: Diagnostics
https://www.readbyqxmd.com/read/29244715/response-characterization-of-an-inexpensive-aerosol-sensor
#18
Joel Kuula, Timo Mäkelä, Risto Hillamo, Hilkka Timonen
Inexpensive aerosol sensors have been considered as a complementary option to address the issue of expensive but low spatial coverage air quality monitoring networks. However, the accuracy and response characteristics of these sensors is poorly documented. In this study, inexpensive Shinyei PPD42NS and PPD60PV sensors were evaluated using a novel laboratory evaluation method. A continuously changing monodisperse size distribution of particles was generated using a Vibrating Orifice Aerosol Generator. Furthermore, the laboratory results were validated in a field experiment...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244697/occipitocervical-fusion-for-severe-atlantoaxial-dislocation-in-an-underdeveloped-child-with-chondrodysplasia-punctata-a-case-report
#19
Yuki Tanaka, Kei Watanabe, Keiichi Katsumi, Masayuki Ohashi, Keisuke Nagasaki, Toru Hirano
CASE: We present a case of brachytelephalangic chondrodysplasia punctata with a severe atlantoaxial dislocation in an underdeveloped child. The patient underwent halo jacket application using 10 halo pins with <1 lb/in of torque, followed by posterior occipitocervical fusion with onlay rib and iliac autografts. After bone grafts and replacement of the halo ring multiple times, successful osseous fusion had been achieved by the 2-year follow-up. CONCLUSION: Although simple bone-grafting with a halo jacket is useful in underdeveloped patients with skeletal dysplasia, the complications related to halo fixation, including cranial bone perforation, and the patient's neurological status must be carefully monitored...
January 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29244678/oncogenic-osteomalacia-secondary-to-a-metastatic-phosphaturic-mesenchymal-tumor-in-the-talus-a-case-report-and-review-of-the-literature
#20
Keith T Aziz, Edward F McCarthy, Carol D Morris
CASE: We report the case of a 50-year-old woman with oncogenic osteomalacia secondary to a metastatic phosphaturic mesenchymal tumor (PMT) that presented, to our knowledge, with the first reported lesion in the talus. CONCLUSION: Oncogenic osteomalacia is a rare condition with a unique serum biochemical profile that requires a high index of suspicion for diagnosis. A PMT is a rare neoplasm that can lead to oncogenic osteomalacia through secretion of fibroblast growth factor 23...
April 2017: JBJS Case Connector
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