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Neurofibrilar tangles

Ioana Cristina Amihăesei, Elena Cojocarut, O C Mungiu
Alzheimer's disease is a degenerative, progressive and irreversible condition, which affects cognitive functions. It was first described in 1907, by the German physician Alois Alzheimer. Although at the time, it was considered a rare disease, in 2010 in the world were estimated 35.6 million cases of dementia, most of these with the diagnosis of Alzheimer's disease. Typical neuropathologic lesions are represented by the amyloid plaques, neurofibrilar tangles and synapses and neurons losses. It was hypothesized that the amyloid protein has prion-like properties...
January 2013: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
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