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lenticule extraction

Alper Ağca, Ahmet Demirok, Yusuf Yıldırım, Ali Demircan, Dilek Yaşa, Ceren Yeşilkaya, İrfan Perente, Muhittin Taşkapılı
Small-incision lenticule extraction (SMILE) is an alternative to laser-assisted in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) for the correction of myopia and myopic astigmatism. SMILE can be performed for the treatment of myopia ≤-12 D and astigmatism ≤5 D. The technology is currently only available in the VisuMax femtosecond laser platform. It offers several advantages over LASIK and PRK; however, hyperopia treatment, topography-guided treatment, and cyclotorsion control are not available in the current platform...
2016: Clinical Ophthalmology
Sara Catalan-Lopez, Alba Mariña Portas-Ferradas, Luis Cadarso-Suarez, Adriana Rodriguez-Rodriguez
PURPOSE: To report the case of a residual refractive error after LASIK for moderate myopia successfully re-treated several years later using the small incision lenticule extraction (SMILE) technique. METHODS: Case report. RESULTS: Following LASIK, the patient showed a central flap thickness of 269 microns, whereas residual stromal bed thickness under the flap was 210 microns. SMILE was performed within the flap. In this less invasive surgical procedure, the residual stromal bed is not manipulated and ablation is conducted on the existing flap...
October 1, 2016: Journal of Refractive Surgery
Jing Zhao, Huamao Miao, Tian Han, Yang Shen, Yu Zhao, Ling Sun, Xingtao Zhou
PURPOSE: To evaluate the corneal morphology and surface characteristics of concave lenticules after small incision lenticule extraction (SMILE) for hyperopia. METHODS: SMILE procedures were performed on two human autopsy corneas in vitro to correct +4.00 diopters of hyperopia. Slit-lamp microscopy and anterior optical coherence tomography (OCT) were performed after lenticule creation and extraction. The extracted lenticules and modified corneas were sent for transmission electron microscopy imaging...
October 1, 2016: Journal of Refractive Surgery
Manli Liu, Jianchao Wang, Wen Zhong, Danyang Wang, Yugui Zhou, Quan Liu
PURPOSE: To evaluate the clinical results of suction loss in eyes during small incision lenticule extraction (SMILE). METHODS: This prospective paired-eye case study enrolled 8,490 eyes of 4,296 patients, of which 35 eyes experienced suction loss during the SMILE procedure while being treated for myopia or myopic astigmatism. The eyes with suction loss were re-treated with SMILE, femtosecond laser-assisted LASIK (FS-LASIK), or pseudo SMILE, and the fellow eyes were treated with SMILE...
October 1, 2016: Journal of Refractive Surgery
Ke Zheng, Tian Han, Xingtao Zhou
BACKGROUND: To investigate accommodative response and accommodative lag changes after femtosecond laser small incision lenticule extraction (SMILE) for moderate to high myopia correction. METHODS: A total of 32 eyes of 32 patients with no strabismus who underwent SMILE were enrolled in this prospective clinical study. The accommodative response was obtained viewing monocularly with spherical equivalent refractive error corrected, using an open-field autorefractor at different stimulus levels (2...
October 4, 2016: BMC Ophthalmology
Rudy Nuijts, An-Katrien de Brauwer
No abstract text is available yet for this article.
September 2016: Journal of Cataract and Refractive Surgery
Soosan Jacob, Ashiyana Nariani, Michele Figus, Amar Agarwal, Athiya Agarwal
: We describe the white ring sign, which differentiates the posterior and anterior lenticular planes in small-incision lenticule extraction. The sign identifies the plane of dissection by the anteroposterior relationship between the dissecting instrument and the circular white light reflected from the lenticular side cut. Differentiating the planes enables the surgeon to dissect the anterior plane before the posterior plane, which facilitates smooth lenticule extraction and prevents complications such as cap tears, partial lenticule dissection, and a torn lenticule...
September 2016: Journal of Cataract and Refractive Surgery
Houfa Yin, Peijin Qiu, Fang Wu, Wei Zhang, Wenqi Teng, Zhenwei Qin, Chao Li, Jiaojie Zhou, Zhi Fang, Qiaomei Tang, Qiuli Fu, Jian Ma, Yabo Yang
The scarcity of corneal tissue to treat deep corneal defects and corneal perforations remains a challenge. Currently, small incision lenticule extraction (SMILE)-derived lenticules appear to be a promising alternative for the treatment of these conditions. However, the thickness and toughness of a single piece of lenticule are limited. To overcome these limitations, we constructed a corneal stromal equivalent with SMILE-derived lenticules and fibrin glue. In vitro cell culture revealed that the corneal stromal equivalent could provide a suitable scaffold for the survival and proliferation of corneal epithelial cells, which formed a continuous pluristratified epithelium with the expression of characteristic markers...
2016: Scientific Reports
X L Su, Y Wang, W J Wu, Z Q Wu, Y N Wu, C J Yu
Objective: To evaluate and compare the anterior corneal asphericity after small incision lenticule extraction(SMILE)and femtosecond laser in situ keratomileusis(FS-LASIK). Methods: In this case-control study, 45 subjects who underwent SMILE operation comprised the study group, and 33 subjects with FS-LASIK operation comprised the control group. The asphericity coefficient Q-value of the right eyes in both groups was measured at diameters of 6, 7, 8 and 9 mm, respectively, before surgery and at 1 day, 1 week, 1 month and 6 months following surgery...
September 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
S Taneri, S Kießler, A Rost, B Dick
Background: Small Incision Lenticule Extraction (SMILE) is a relatively new surgical method to correct myopia and myopic astigmatism. Although considered to be safe and effective, it is not yet popular. Potential reasons for its limited use could be that surgeons fear inferior results and a higher complication rate in the learning phase. Therefore we present our experiences with the treatment of our first 200 eyes, with special attention to refraction results, complications, and learning curve. Patients and Methods: 200 myopic or myopic astigmatic eyes of 102 patients were treated with SMILE...
September 19, 2016: Klinische Monatsblätter Für Augenheilkunde
Leonardo Mastropasqua, Mario Nubile
PURPOSE: To investigate the feasibility of the procedure and the modifications of the corneal curvature and profile obtained with a novel technique of stromal-lentoid implantation in ex vivo human corneas. DESIGN: Experimental ex vivo study in human corneas. MATERIALS AND METHODS: Twelve stromal lentoids were produced by means of hyperopic femtosecond lenticule extraction (FLEx) with the VisuMax femtosecond laser (Carl Zeiss Meditec, Jena, Germany) with a refractive power of +8...
September 15, 2016: International Ophthalmology
Tommy C Y Chan, Marco C Y Yu, Alex Ng, Zheng Wang, George P M Cheng, Vishal Jhanji
We prospectively compared visual and refractive outcomes in patients with high myopia and myopic astigmatism after small-incision lenticule extraction (SMILE) and photorefractive keratetctomy (PRK) with mitomycin C. Sixty-six eyes of 33 patients (mean age, 29.7 ± 5.6 years) were included (SMILE: 34 eyes, PRK 32 eyes). Preoperatively, no significant difference was noted in manifest spherical equivalent (p = 0.326), manifest sphere (p = 0.277), and manifest cylinder (p = 0.625) between both groups...
2016: Scientific Reports
Bu Ki Kim, Su Joung Mun, Dae Gyu Lee, Young Taek Chung
PURPOSE: To report a case of successful bilateral small incision lenticule extraction (SMILE) performed on a patient who had penetrating keratoplasty and astigmatic keratotomy in the right eye and penetrating keratoplasty in the left eye. METHODS: Case report. RESULTS: Astigmatic keratotomy was used to reduce astigmatism of the right eye because astigmatism was higher than the maximum correction limitation of SMILE. Bilateral SMILE was performed afterward...
August 1, 2016: Journal of Refractive Surgery
David Donate, Rozenn Thaëron
PURPOSE: To compare the visual outcomes with energy close to the plasma threshold and energy at the standard set-up in small incision lenticule extraction (SMILE). METHODS: This retrospective, non-randomized, consecutive clinical case series included 486 eyes of 243 patients who underwent SMILE and were subdivided into two groups depending on the laser energy settings: the standard energy group (164 eyes) using a laser cut energy index of 36 (180 nJ), and the plasma threshold group (322 eyes) using a cut energy index of 20 (100 nJ, close to plasma threshold)...
August 1, 2016: Journal of Refractive Surgery
Yusuf Yildirim, Onur Olcucu, Cengiz Alagoz, Abdurrahman Basci, Alper Agca, Dilek Yasa, Engin Bilge Ozgurhan, Ahmet Demirok
PURPOSE: To compare the refractive outcomes of small incision lenticule extraction (SMILE) with photorefractive keratectomy (PRK) using an aberration-free ablation profile. METHODS: One eye of patients diagnosed as having myopia for bilateral refractive correction was randomly allocated to either PRK or SMILE. The primary outcome measures included refractive efficacy, predictability, safety, stability, corneal aberrations, and adverse events. Patients were followed up for 1 year postoperatively; postoperative uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction, and corneal aberrations were recorded and compared with preoperative data...
August 1, 2016: Journal of Refractive Surgery
Bu Ki Kim, Su Joung Mun, Dae Gyu Lee, Hyun Tae Choi, Young Taek Chung
BACKGROUND: To introduce the Chung's swing technique for small-incision lenticule extraction (SMILE). METHODS: A total of 112 eyes of 56 patients were included in this study. Patients were divided into two groups: 52 eyes of 26 patients were treated with SMILE using a traditional method (traditional group) and 60 eyes of 30 patients were treated with SMILE using the Chung's swing technique (swing group). RESULTS: At 1 month postoperatively, all eyes in both groups had an uncorrected distance visual acuity of 20/20 or better...
2016: BMC Ophthalmology
Tian Han, Ke Zheng, Yingjun Chen, Yang Gao, Li He, Xingtao Zhou
BACKGROUND: To investigate long-term refractive outcomes, wavefront aberrations and quality of life after small incision lenticule extraction (SMILE) for moderate to high myopia. METHODS: A total of 26 patients (47 eyes) with preoperative mean spherical equivalent (SE) of -6.30 ± 1.47 diopters (D) who underwent SMILE were recruited. The measurements included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction, wavefront aberrations, and quality of life...
2016: BMC Ophthalmology
Hidenaga Kobashi, Kazutaka Kamiya, Kimiya Shimizu
PURPOSE: To compare postoperative ocular surface integrity and innervation between small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK). METHODS: The Cochrane Central Register of Controlled Trials, PubMED, and EMBASE were searched for prospective comparative studies. Trials meeting the selection criteria were quality appraised, and the data were extracted by 2 independent authors. The weighted mean differences (WMDs) and 95% confidence intervals (CIs) were used to compare dry eye examinations and corneal subbasal nerve density (SMILE-FS-LASIK)...
August 24, 2016: Cornea
Hua Li, Yan Wang, Rui Dou, Pinghui Wei, Jiamei Zhang, Wei Zhao, Liuyang Li
PURPOSE: The purpose of this article was to evaluate intraocular pressure (IOP) changes and investigate the relationship with corneal biomechanics after small-incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK). METHODS: A total of 193 eyes of 193 patients who underwent SMILE and FS-LASIK procedures were included in this retrospective study. Data were collected preoperatively and postoperatively, including Goldmann-correlated IOP (IOPg), corneal-compensated IOP (IOPcc), corneal hysteresis (CH), and corneal resistance factor (CRF) by ocular response analyzer, noncontact intraocular pressure (IOPNCT) by noncontact tonometer, and Ehlers, Shah, Dresden, Kohlhaas, Orssengo/Pye by the Pentacam corrected system...
August 1, 2016: Investigative Ophthalmology & Visual Science
Zhiqing Wu, Yan Wang, Jiamei Zhang, Tommy C Y Chan, Alex L K Ng, George P M Cheng, Vishal Jhanji
OBJECTIVES: To evaluate and compare the change in corneal biomechanical properties after microincision lenticule extraction (MILE) and small incision lenticule extraction (SMILE). METHODS: In this prospective study, 60 eyes received MILE surgery with 2 mm opening incision, while 64 eyes received SMILE procedure with 5 mm opening incision. Corneal hysteresis (CH), corneal resistance factor (CRF) and 37 other biomechanical waveform parameters were quantitatively assessed using ocular response analyser (ORA) preoperatively and up to 6 months postoperatively...
August 19, 2016: British Journal of Ophthalmology
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