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Antepartum depression

Babette Bais, Astrid M Kamperman, Marjolein D van der Zwaag, Gwen C Dieleman, Hanneke W Harmsen van der Vliet-Torij, Hilmar H Bijma, Ritsaert Lieverse, Witte J G Hoogendijk, Mijke P Lambregtse-van den Berg
BACKGROUND: Depression during pregnancy is a common and high impact disease. Generally, 5-10 % of pregnant women suffer from depression. Children who have been exposed to maternal depression during pregnancy have a higher risk of adverse birth outcomes and more often show cognitive, emotional and behavioural problems. Therefore, early detection and treatment of antepartum depression is necessary. Both psychotherapy and antidepressant medication, first choice treatments in a non-pregnant population, have limitations in treating depression during pregnancy...
November 8, 2016: BMC Psychiatry
D Elizabeth Jesse, Hui Bian, Elizabeth C Banks, Bradley N Gaynes, Steve D Hollon, Edward R Newton
Although cognitive behavioral interventions (CBIs) have demonstrated effectiveness for reducing depressive symptoms in the general population, the mechanism for reducing antepartum depressive symptoms (APDS) in rural low-income and minority women is unknown. This study tested the hypothesis that reducing stress and negative thinking, enhancing self-esteem, and increasing social-support will mediate the effect of a CBI on reducing APDS in rural low-income and minority women. Our findings show that CBI may work through reducing stress and negative thinking and enhancing self-esteem, but not social support...
November 2016: Issues in Mental Health Nursing
Bizu Gelaye, Marta B Rondon, Ricardo Araya, Michelle A Williams
Maternal depression, a non-psychotic depressive episode of mild to major severity, is one of the major contributors of pregnancy-related morbidity and mortality. Maternal depression (antepartum or post partum) has been linked to negative health-related behaviours and adverse outcomes, including psychological and developmental disturbances in infants, children, and adolescents. Despite its enormous burden, maternal depression in low-income and middle-income countries remains under-recognised and undertreated...
October 2016: Lancet Psychiatry
Arthur H Owora, Hélène Carabin, Jessica Reese, Tabitha Garwe
INTRODUCTION: Major Depression Disorder (MDD) is common among mothers of young children. However, its detection remains low in primary-care and community-based settings in part due to the uncertainty regarding the validity of existing case-finding instruments. We conducted meta-analyses to estimate the diagnostic validity of commonly used maternal MDD case finding instruments in the United States. METHODS: We systematically searched three electronic bibliographic databases PubMed, PsycINFO, and EMBASE from 1994 to 2015 to identify relevant published literature...
November 15, 2016: Journal of Affective Disorders
T A Supraja, K Thennarasu, Veena A Satyanarayana, T K Seena, Geetha Desai, Kavita V Jangam, Prabha S Chandra
This study assessed the prevalence and predictors of suicidality among 462 pregnant women in South India. Women in early pregnancy (<20 weeks) attending an urban public hospital antenatal center were assessed for suicidality using a modified version of the Suicide Behaviors Questionnaire-Revised (SBQR) and a single-item (item 10) from the Edinburgh Postnatal Depression Scale (EPDS). Severity of depressive symptoms, family violence, and perceived social support were also measured. The prevalence of suicidality in pregnancy was 7...
August 26, 2016: Archives of Women's Mental Health
Sarah Hain, Silvia Oddo-Sommerfeld, Franz Bahlmann, Frank Louwen, Karin Schermelleh-Engel
INTRODUCTION: Antepartum risk and protective factors for postpartum depression (PPD; the most common mental disorder after childbirth besides postpartum anxiety), have been frequently investigated in cross-sectional studies, but less often longitudinally. This study examined linear and moderator effects of risk and protective factors for peripartum depression. First, we investigated the predictive power of risk factors (physical problems during pregnancy, pregnancy-related anxiety, stressful life events, dysfunctional self-consciousness (DSC)) and protective factors (resilience, social support) for antepartum depression (APD) and PPD...
July 4, 2016: Journal of Psychosomatic Obstetrics and Gynaecology
Bizu Gelaye, Sandhya Kajeepeta, Michelle A Williams
Suicidal behaviors are the leading causes of injury and death worldwide, and are leading causes of maternal deaths in some countries. One of the strongest risk factors, suicidal ideation, is considered a harbinger and distal predictor of later suicide attempt and completion, and also presents an opportunity for interventions prior to physical self-harm. The purpose of this systematic epidemiologic review is to synthesize available research on antepartum suicidal ideation. Original publications were identified through searches of the electronic databases using the search terms pregnancy, pregnant women, suicidal ideation, and pregnan* and suicid* as root searches...
October 2016: Archives of Women's Mental Health
Arthur H Owora, Hélène Carabin, Jessica Reese, Tabitha Garwe
INTRODUCTION: Growing recognition of the interrelated negative outcomes associated with major depression disorder (MDD) among mothers and their children has led to renewed public health interest in the early identification and treatment of maternal MDD. Healthcare providers, however, remain unsure of the validity of existing case-finding instruments. We conducted a systematic review to identify the most valid maternal MDD case-finding instrument used in the United States. METHODS: We identified articles reporting the sensitivity and specificity of MDD case-finding instruments based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) by systematically searching through three electronic bibliographic databases, PubMed, PsycINFO, and EMBASE, from 1994 to 2014...
September 1, 2016: Journal of Affective Disorders
Susan Bodnar-Deren, Kimberly Klipstein, Madeleine Fersh, Eyal Shemesh, Elizabeth A Howell
OBJECTIVE: To examine the association between suicidal ideation (SI), 3 weeks, 3 months, and 6 months postpartum with demographic, psychosocial, clinical factors, and depressive/anxiety symptoms (measured 24-48 hours after delivery), among a cohort of postpartum women. METHODS: This study included 1,073 mothers who gave birth in a large tertiary New York City hospital (2009-2010). Later, self-report SI was assessed using the suicide measure from the Edinburgh Postnatal Depression Scale and from the Patient Health Questionnaire...
May 26, 2016: Journal of Women's Health
Kartik K Venkatesh, Hiyam Nadel, Dyan Blewett, Marlene P Freeman, Anjali J Kaimal, Laura E Riley
BACKGROUND: Given the growing policy and public health interest in the identification and treatment of depression in pregnancy, an understanding of the feasibility, challenges, and implications for resource utilization of the implementation of a universal screening program is crucial. OBJECTIVE: The purpose of this study was to assess the feasibility of large-scale implementation of universal screening for depression in pregnancy and during the postpartum period with the use of the Edinburgh Postnatal Depression Scale...
October 2016: American Journal of Obstetrics and Gynecology
Na Yang, Bizu Gelaye, Qiuyue Zhong, Marta B Rondon, Sixto E Sanchez, Michelle A Williams
There is accumulating evidence for the role of brain-derived neurotrophic factor (BDNF) in the pathophysiology of depression. However, the role of BDNF in the pathophysiology of post-traumatic stress disorder (PTSD) remains controversial, and no study has assessed BDNF concentrations among pregnant women with PTSD. We examined early-pregnancy BDNF concentrations among women with PTSD with and without depression. A total of 2928 women attending prenatal care clinics in Lima, Peru, were recruited. Antepartum PTSD and depression were evaluated using PTSD Checklist-Civilian Version (PCL-C) and Patient Health Questionnaire-9 (PHQ-9) scales, respectively...
December 2016: Archives of Women's Mental Health
Qiu-Yue Zhong, Anne Wells, Marta B Rondon, Michelle A Williams, Yasmin V Barrios, Sixto E Sanchez, Bizu Gelaye
BACKGROUND: Childhood abuse is a major global and public health problem associated with a myriad of adverse outcomes across the life course. Suicide is one of the leading causes of mortality during the perinatal period. However, few studies have assessed the relationship between experiences of childhood abuse and suicidal ideation in pregnancy. OBJECTIVE: We sought to examine the association between exposure to childhood abuse and suicidal ideation among pregnant women...
October 2016: American Journal of Obstetrics and Gynecology
Margaret G Spinelli, Jean Endicott, Ray R Goetz, Lisa S Segre
OBJECTIVE: Interpersonal psychotherapy (IPT) is supported by substantial empirical evidence as a treatment for depression. Surprisingly, our recently reported randomized, single-blind, controlled clinical trial found no significant difference between interpersonal psychotherapy for antepartum depression (IPT-P) and a parenting education program (PEP) control condition for the treatment of prenatal depression. Because depression severity has been found to influence treatment response in antidepressant treatment trials, the current study reassessed IPT-P outcomes, limiting analyses to women with moderate depressive symptoms...
April 2016: Journal of Clinical Psychiatry
Kartik K Venkatesh, Laura Riley, Victor M Castro, Roy H Perlis, Anjali J Kaimal
OBJECTIVE: To evaluate the association of antenatal depression symptoms with preterm birth and small for gestational age (SGA). METHODS: This was an observational cohort study conducted among women who completed Edinburgh Postnatal Depression Scale screening and delivered at 20 weeks of gestation or greater. The primary outcomes were preterm birth and an SGA neonate at birth (less than 10th percentile for gestational age); the primary predictor was an Edinburgh Postnatal Depression Scale antepartum score of 10 or greater, indicating symptoms of depression...
May 2016: Obstetrics and Gynecology
Dana Barthel, Levente Kriston, Claus Barkmann, John Appiah-Poku, Marguerite Te Bonle, Kra Yao Esther Doris, Bony Kotchi Carine Esther, Koffi Ekissi Jean Armel, Yasmin Mohammed, Yaw Osei, Daniel Fordjour, Dorcas Owusu, Kirsten A Eberhardt, Rebecca Hinz, Mathurin Koffi, Eliezer N'Goran, Samuel Blay Nguah, Harry Tagbor, Stefanie Schoppen, Stephan Ehrhardt, Carola Bindt
BACKGROUND: Little is known about the course of perinatal anxiety, particularly in low and middle income countries. This study aimed at examining trajectories of ante- and postpartum generalized anxiety symptoms in West-African women and their associations with mother and child characteristics. METHODS: 778 women from Côte d'Ivoire and Ghana were investigated between 04/2010 and 03/2014. Anxiety symptoms were measured using the seven-item Generalized Anxiety Disorder scale (GAD-7) at three months antepartum and three, 12 and 24 months postpartum...
June 2016: Journal of Affective Disorders
Kristina M Deligiannidis, Aimee R Kroll-Desrosiers, Abby Svenson, Nina Jaitly, Bruce A Barton, Janet E Hall, Anthony J Rothschild
Antepartum depression and anxiety are risk factors for postpartum depression (PPD). Postpartum abnormalities in hypothalamic-pituitary-adrenal (HPA) reactivity are associated with PPD. It is not known if antepartum HPA abnormalities exist in women at risk for PPD (AR-PPD). We measured salivary cortisol response to the Trier Social Stress Test (TSST) in 44 (24 AR-PPD, 20 healthy comparison) pregnant women. Depression and anxiety were measured using the Edinburgh Postnatal Depression Scale (EPDS) and Spielberger State-Trait Anxiety Inventory-State (STAI-S)...
October 2016: Archives of Women's Mental Health
Mats Målqvist, Kelly Clarke, Themba Matsebula, Mattias Bergman, Mark Tomlinson
Maternal depression, including antepartum and postpartum depression, is a neglected public health issue with potentially far-reaching effects on maternal and child health. We aimed to measure the burden of antepartum depression and identify risk factors among women in a peri-urban community in Swaziland. We conducted a cross-sectional study within the context of a community outreach peer support project involving "Mentor Mothers". We used of the Edinburgh Postnatal Depression Scale (EPDS) to screen women for depression during the third trimester of pregnancy, using a cut-off score of ≥13 to indicate depression...
October 2016: Journal of Community Health
Bizu Gelaye, Qiu-Yue Zhong, Yasmin V Barrios, Susan Redline, Christopher L Drake, Michelle A Williams
STUDY OBJECTIVES: To evaluate the construct validity and factor structure of the Spanish-language version of the Ford Insomnia Response to Stress Test questionnaire (FIRST-S) when used in early pregnancy. METHODS: A cohort of 647 women were interviewed at ≤ 16 weeks of gestation to collect information regarding lifestyle, demographic, and sleep characteristics. The factorial structure of the FIRST-S was tested through exploratory and confirmatory factor analyses (EFA and CFA)...
April 15, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Silvia Oddo-Sommerfeld, Sarah Hain, Frank Louwen, Karin Schermelleh-Engel
BACKGROUND: There is first evidence that some personality characteristics raise the risk of postpartum depression (PPD). The present longitudinal study investigates whether dysfunctional perfectionism and avoidant personality style predict PPD, postpartum anxiety (PPA) and bonding impairment (BI) directly or indirectly through antepartum anxiety (APA) and antepartum depression (APD). METHODS: Pregnant women were recruited in two obstetric departments in Germany...
February 2016: Journal of Affective Disorders
Nancy Jallo, R K Elswick, Patricia Kinser, Saba Masho, Sarah Kye Price, Dace S Svikis
African American women may be especially vulnerable to antepartum depression, a major health concern during pregnancy. This study investigated the prevalence and predictors of depressive symptoms in a sample of African American women who were between 14-17 weeks pregnant, a timeframe that is typically thought to be a time of general well-being. Two-thirds reported a CES-D score ≥ 16 indicative of depressive symptomatology. Age, perceived stress (as measured by the Perceived Stress Scale [PSS]), and anxiety (as measured by the State Trait Anxiety Inventory [STAI]) predicted depressive symptoms; the interaction between PSS and STAI scores was also a significant predictor...
2015: Issues in Mental Health Nursing
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