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https://www.readbyqxmd.com/read/29677384/risk-factors-and-long-term-outcomes-of-pediatric-liver-transplant-recipients-with-chronic-high-epstein-barr-virus-loads
#1
Hideya Kamei, Yoshinori Ito, Junichi Kawada, Satoshi Ogiso, Yasuharu Onishi, Masahiko Komagome, Nobuhiko Kurata, Yasuhiro Ogura
BACKGROUND: Serial monitoring of Epstein-Barr virus (EBV) reveals that certain pediatric liver transplant (LT) recipients exhibit high EBV loads for long periods. We investigated the incidence and risk factors of chronic high EBV (CHEBV) loads (continuous EBV DNA >10000 IU/mL of whole blood for ≥6 months) and long-term outcomes. METHODS: This single center, retrospective observational study investigated pediatric LT recipients who survived ≥6 months. We quantitated EBV DNA weekly during hospitalization and subsequently every 4 or 6 weeks at the outpatient clinic...
April 20, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29677212/pulsatile-operation-of-a-continuous-flow-right-ventricular-assist-device-rvad-to-improve-vascular-pulsatility
#2
Boon C Ng, Matthias Kleinheyer, Peter A Smith, Daniel Timms, William E Cohn, Einly Lim
Despite the widespread acceptance of rotary blood pump (RBP) in clinical use over the past decades, the diminished flow pulsatility generated by a fixed speed RBP has been regarded as a potential factor that may lead to adverse events such as vasculature stiffening and hemorrhagic strokes. In this study, we investigate the feasibility of generating physiological pulse pressure in the pulmonary circulation by modulating the speed of a right ventricular assist device (RVAD) in a mock circulation loop. A rectangular pulse profile with predetermined pulse width has been implemented as the pump speed pattern with two different phase shifts (0% and 50%) with respect to the ventricular contraction...
2018: PloS One
https://www.readbyqxmd.com/read/29677115/subjective-socioeconomic-status-moderates-the-association-between-discrimination-and-depression-in-african-american-youth
#3
Shervin Assari, Brianna Preiser, Maryam Moghani Lankarani, Cleopatra H Caldwell
Background: Most of the literature on the association between socioeconomic status (SES) and health is focused on the protective effects of SES. However, a growing literature suggests that high SES may also operate as a vulnerability factor. Aims: Using a national sample of African American youth, this study compared the effects of perceived discrimination on major depressive disorder (MDD) based on SES. Methods: The current cross-sectional study included 810 African American youth who participated in the National Survey of American Life-Adolescent supplement...
April 20, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29677094/local-antibiotic-therapy-to-reduce-infection-after-operative-treatment-of-fractures-at-high-risk-of-infection-a-multicenter-randomized-controlled-trial-vanco-study-erratum
#4
(no author information available yet)
No abstract text is available yet for this article.
May 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29677057/newborn-resuscitation-skills-in-health-care-providers-at-a-zambian-tertiary-center-and-comparison-to-world-health-organization-standards
#5
Sara C Mistry, Richard Lin, Hazel Mumphansha, Laura C Kettley, Janaki A Pearson, Sonia Akrimi, David J Mayne, Wonder Hangoma, M Dylan Bould
BACKGROUND: Birth asphyxia is a leading cause of early neonatal death. In 2013, 32% of neonatal deaths in Zambia were attributable to birth asphyxia and trauma. Basic, timely interventions are key to improving outcomes. However, data from the World Health Organization suggest that resuscitation is often not initiated, or is conducted suboptimally. Currently, there are little data on the quality of newborn resuscitation in the context of a tertiary center in a lower-middle income country...
April 17, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29677051/electrocardiographic-predictors-of-atrial-fibrillation-in-nonhypertensive-and-hypertensive-individuals
#6
Arttu O Lehtonen, Ville L Langén, Kimmo Porthan, Mika Kähönen, Markku S Nieminen, Antti M Jula, Teemu J Niiranen
OBJECTIVE: The aim of this study was to compare the predictive value of ECG abnormalities for atrial fibrillation in nonhypertensive versus hypertensive individuals. METHODS: We recorded ECG and measured conventional cardiovascular risk factors in a nationwide population-based sample of 5813 Finns. We divided the participants into nonhypertensive (n = 3148) and hypertensive (n = 2665) individuals and followed the participants for incident atrial fibrillation events...
April 19, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29677021/pericardial-patch-exclusion-technique-for-left-atrial-appendage-closure
#7
Olivia K Ginty, Feras H Khaliel, Corey Adams, Michael W A Chu
We describe a technique of left atrial appendage occlusion that consists of autologous pericardial patch closure of the left atrial appendage orifice from within the left atrium. This pericardial patch exclusion technique has little added risk of bleeding, can be performed through sternotomy or right minithoracotomy, and can be used in re-operative situations.
April 19, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29676943/impact-of-preoperative-thrombocytopenia-on-the-outcome-after-coronary-artery-bypass-grafting
#8
Wail Nammas, Magnus Dalén, Stefano Rosato, Riccardo Gherli, Daniel Reichart, Giuseppe Gatti, Francesco Onorati, Giuseppe Faggian, Marisa De Feo, Ciro Bancone, Sidney Chocron, Sorosh Khodabandeh, Giuseppe Santarpino, Antonino S Rubino, Daniele Maselli, Saverio Nardella, Antonio Salsano, Tiziano Gherli, Francesco Nicolini, Marco Zanobini, Matteo Saccocci, Karl Bounader, Paola D'Errigo, Tuomas Kiviniemi, Eeva-Maija Kinnunen, Andrea Perrotti, Juhani Airaksinen, Giovanni Mariscalco, Vito G Ruggieri, Fausto Biancari
The impact of thrombocytopenia on postoperative bleeding and other major adverse events after cardiac surgery is unclear. This issue was investigated in a series of patients who underwent isolated coronary artery bypass grafting (CABG) from the prospective, multicenter E-CABG registry. Preoperative thrombocytopenia was defined as preoperative platelet count <150 × 109 /L and it was considered moderate-severe when preoperative platelet count was <100 × 109 /L. Multilevel mixed-effects regression analysis was performed to adjust the effect of thrombocytopenia on outcomes for baseline and operative covariates as well as for interinstitutional differences in patient-blood management...
April 20, 2018: Platelets
https://www.readbyqxmd.com/read/29676803/outcome-of-the-risk-stratified-desensitization-protocol-in-donor-specific-antibody-positive-living-kidney-transplant-recipients-a-retrospective-study
#9
Daigo Okada, Masayoshi Okumi, Yoichi Kakuta, Kohei Unagami, Junpei Iizuka, Toshio Takagi, Hideki Ishida, Kazunari Tanabe
Acceptable outcomes of donor-specific antibody (DSA)-positive living kidney transplantation (LKT) have recently been reported. However, LKT in crossmatch (XM)-positive patients remains at high-risk and requires an optimal desensitization protocol. We report our intermediate-term outcomes of XM-positive LKT versus XM-negative LKT in patients who underwent LKT between January 2012 and June 2015 in our institution. The rate of acute antibody-mediated rejection (ABMR) within 90 days post-operation, graft function, and patient and graft survival rates at 4 years were investigated...
April 20, 2018: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29676737/full-scale-dissolved-air-flotation-daf-equipment-for-emergency-treatment-of-eutrophic-water
#10
Zhuang Tian, Can Wang, Min Ji
Eutrophication of urban rivers has caused severe environmental problems due to the pollution from point and diffuse sources. Although eutrophication can be alleviated by reducing the input to the river system, fast-treating terminal control technologies, especially under emergent situations, should be developed to reduce risks induced by eutrophication. The present study developed an emergency purification device based on dissolved air flotation (DAF) technology. After equipment commissioning and parameter optimization for applications in the field of engineering, the device was found to effectively remove total phosphorus, chlorophyll a, chemical oxygen demand, and turbidity in water by controlling the coagulant dosage and adjusting the gas-liquid mixing pump parameters...
April 2018: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29676711/-intraoperative-neuromonitoring-in-endocrine-surgery-when-is-it-appropriate
#11
A F Engelsman, E J M Nieveen van Dijkum
The use of intraoperative neuromonitoring (IONM) in thyroid surgery has steadily increased in recent years. This technique helps to identify different nerves in and around the operation site, such as the recurrent laryngeal nerve (RLN) and the external branch of the superior laryngeal nerve. Particularly in patients who undergo a second operation or a complex procedure for malignancy, the technique's value has been demonstrated. However, in non-complex thyroid operations the risk of vocal cord paresis due to iatrogenic injury of the RLN is 0...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29676628/increasing-the-resolution-of-chronic-obstructive-pulmonary-disease-definition-lessons-from-a-cohort-with-remote-but-extensive-exposure-to-secondhand-tobacco-smoke
#12
Mehrdad Arjomandi, Siyang Zeng, Paul D Blanc, Warren M Gold
RATIONALE: The Global Initiative for Chronic Obstructive Lung Disease criteria require a ratio of forced expiratory volume in 1 second (FEV1 ) to forced vital capacity (FVC) (FEV1 /FVC) of less than 0.70 for the diagnosis of chronic obstructive pulmonary disease, whereas other criteria emphasize a lower limit of normal approach. However, the use of Global Initiative for Chronic Obstructive Lung Disease (or lower limit of normal) criteria may result in classification of many smokers with respiratory morbidities as not having chronic obstructive pulmonary disease...
April 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29675673/systematic-review-of-the-complications-associated-with-magnetically-controlled-growing-rods-for-the-treatment-of-early-onset-scoliosis
#13
REVIEW
Chrishan Thakar, David Christopher Kieser, Mihai Mardare, Shahnawaz Haleem, Jeremy Fairbank, Colin Nnadi
PURPOSE: To analyse the complication profile of magnetically controlled growing rods (MCGRs) in early onset scoliosis (EOS). METHODS: This is a systematic review using PUBMED, Medline, Embase, Google Scholar and the Cochrane Library (keywords: MAGEC, Magnetically controlled growing rods and EOS) of all studies written in English with a minimum of five patients and a 1-year follow-up. We evaluated coronal correction, growth progression (T1-S1, T1-T12) and complications...
April 19, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29675658/iodine-concentration-a-new-important-characteristic-of-the-spot-sign-that-predicts-haematoma-expansion
#14
Fan Fu, Shengjun Sun, Liping Liu, Jianying Li, Yaping Su, Yingying Li
OBJECTIVES: The computed tomography angiography (CTA) spot sign is a validated predictor of haematoma expansion (HE) in spontaneous intracerebral haemorrhage (SICH). We investigated whether defining the iodine concentration (IC) inside the spot sign and the haematoma on Gemstone spectral imaging (GSI) would improve its sensitivity and specificity for predicting HE. METHODS: From 2014 to 2016, we prospectively enrolled 65 SICH patients who underwent single-phase spectral CTA within 6 h...
April 19, 2018: European Radiology
https://www.readbyqxmd.com/read/29675629/-geriatric-trauma-center-dgu%C3%A2-evaluation-of-clinical-and-economic-parameters-a-pilot-study-in-a-german-university-hospital
#15
M Knobe, B Böttcher, M Coburn, T Friess, L C Bollheimer, H J Heppner, C J Werner, J-P Bach, M Wollgarten, S Poßelt, C Bliemel, B Bücking
BACKGROUND: Previous studies on orthogeriatric models of care suggest that there is substantial variability in how geriatric care is integrated in the patient management and the necessary intensity of geriatric involvement is questionable. OBJECTIVE: The aim of the current prospective cohort study was the clinical and economic evaluation of fragility fracture treatment pathways before and after the implementation of a geriatric trauma center in conformity with the guidelines of the German Trauma Society (DGU)...
April 19, 2018: Der Unfallchirurg
https://www.readbyqxmd.com/read/29675590/oncological-outcomes-of-ibd-associated-versus-sporadic-colorectal-cancer-in-modern-era-a-matched-case-control-study
#16
Antoine Thicoïpé, David Laharie, Denis Smith, Edouard Chabrun, Anne Rullier, Florian Poullenot, Eric Rullier, Quentin Denost
AIM: Inflammatory bowel diseases (IBD) are associated with an increased risk for colorectal cancer (CRC). However and despite significant advances in the management of IBD and CRC, the prognosis of IBD-related CRC (IBD-CRC) remains controversial. The aim of the present case-control study was to compare the prognosis of IBD-CRC to sporadic CRC. METHODS: Consecutive patients operated for IBD-CRC from 2004 to 2014 were recruited and matched with sporadic CRC (ratio 3:1) from the same center...
April 19, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29675105/association-of-wwox-rs9926344-polymorphism-with-poor-prognosis-of-hepatocellular-carcinoma
#17
Wanyong Chen, Chenhao Zhou, Wentao Zhang, Manar Atyah, Yirui Yin, Lei Guo, Weiguo Tang, Qiongzhu Dong, Qinghai Ye, Ning Ren
Introduction: The WW domain-containing oxidoreductase (WWOX), widely expressed in human tissues, is considered as a tumor suppressor gene and plays an important role in the incidence and progression of human cancer, HCC included. This study was to investigate the correlation between single nucleotide polymorphisms (SNPs) of the WWOX gene and the prognosis of hepatocellular carcinoma (HCC) patients. Materials and Methods: After a total of 152 HCC patients were recruited, 8 cases with tumor recurrence within 2-years after operation and 8 cases without recurrence were selected randomly for SNP genotyping and screening using Affymetrix Array 6...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29675068/cerebellar-mutism-syndrome-following-midline-posterior-fossa-tumor-resection-in-children-an-institutional-experience
#18
Nand Kishore Gora, Ashok Gupta, Virendra Deo Sinha
Aim: Cerebellar mutism (CM) syndrome is a well-known and annoying complication of posterior fossa surgery in the pediatric age group. Risk factors such as the type of tumor, size, involvement of posterior fossa structures and hydrocephalus, and postoperative cerebellar swelling for CM were investigated in this study. Materials and Methods: A consecutive series of 33 children with midline posterior fossa tumors were operated at the SMS Medical College and Hospital, Department of Neurosurgery, Jaipur India, between September 2015 and December 2016...
October 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29675061/comorbidities-with-non-small-cell-lung-cancer-is-there-an-interdisciplinary-consensus-needed-to-qualify-patients-for-surgical-treatment
#19
Marta Lembicz, Piotr Gabryel, Beata Brajer-Luftmann, Wojciech Dyszkiewicz, Halina Batura-Gabryel
INTRODUCTION: Radical surgical treatment is the preferred action for patients with early-stage non-small cell lung cancer (NSCLC). Qualification for surgical treatment should consider a risk associated with the effect of comorbidities on the general condition of the patient. The aim of this article was an attempt to identify the risk factors for postoperative complications in patients treated for NSCLC, with a special focus on the coexisting diseases. METHODS: A total of 400 patients with NSCLC were included in this retrospective study...
April 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29674732/evaluation-of-cardiac-risk-in-dental-patients
#20
N J Ransford, L K Stenhouse, J Townend, P Jordan, H Singh
Patients with cardiac disease, cardiac symptoms and related co-morbidities are increasingly being encountered in dental practice. Current methods of medical risk assessment can however be problematic. This paper represents a multi-speciality consensus on how to identify patients that may be more at risk of an adverse cardiac event occurring perio-operatively i.e. during or in the first few weeks after a dental procedure. Drawing on guidelines for surgery and the available literature, we present on an algorithm which aims to inform dental practitioners' decisions about which patients can be managed in primary care and which should be considered for assessment by a dental specialist together with a methodology thereof...
April 20, 2018: British Dental Journal
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