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https://www.readbyqxmd.com/read/28724125/comparison-of-wound-complications-after-immediate-delayed-and-secondary-breast-reconstruction-procedures
#1
Margaret A Olsen, Katelin B Nickel, Ida K Fox, Julie A Margenthaler, Anna E Wallace, Victoria J Fraser
Importance: Few data are available concerning surgical site infection (SSI) and noninfectious wound complications (NIWCs) after delayed (DR) and secondary reconstruction (SR) compared with immediate reconstruction (IR) procedures in the breast. Objective: To compare the incidence of SSI and NIWCs after implant and autologous IR, DR, and SR breast procedures after mastectomy. Design, Setting, and Participants: This retrospective cohort study included women aged 18 to 64 years undergoing mastectomy from January 1, 2004, through December 31, 2011...
July 19, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28724017/food-risk-regulation-the-tensions-of-the-brazilian-health-surveillance-system
#2
Ana Virgínia Almeida Figueiredo, Elisabetta Recine, Renata Monteiro
This article addresses the dynamics of Brazilian food control practices, highlighting their special risk-related features and the types of intervention, as well as the recently adopted instruments to control risks related to the nutritional composition of food and their institutional repercussions. Food regulation in Brazil dates back to the First Republic. The practice has been remodeled over the years, due to both the increasing complexity of the risks and the introduction of new institutional operational mechanisms...
July 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28723873/total-disc-arthroplasty-and-anterior-interbody-fusion-in-the-lumbar-spine-have-relatively-few-differences-in-readmission-and-short-term-adverse-events
#3
Blake N Shultz, Alexander T Wilson, Nathaniel T Ondeck, Patawut Bovonratwet, Ryan P McLynn, Jonathan J Cui, Jonathan N Grauer
STUDY DESIGN: Retrospective matched cohort study of prospectively collected data. OBJECTIVE: To compare rates of adverse events and readmission between lumbar total disc arthroplasty (TDA) and anterior lumbar interbody fusion (ALIF) using the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database. SUMMARY OF BACKGROUND DATA: TDA and ALIF may be considered for similar degenerative indications. However, there have been few large-cohort comparison studies of short-term clinical outcomes for these procedures...
July 18, 2017: Spine
https://www.readbyqxmd.com/read/28723794/thrombosis-and-antiphospholipid-antibody-syndrome-during-acute-q-fever-a-cross-sectional-study
#4
Matthieu Million, Nathalie Bardin, Simon Bessis, Nadia Nouiakh, Charlaine Douliery, Sophie Edouard, Emmanouil Angelakis, Annick Bosseray, Olivier Epaulard, Stéphanie Branger, Bernard Chaudier, Karine Blanc-Laserre, Nicole Ferreira-Maldent, Elisa Demonchy, France Roblot, Jacques Reynes, Felix Djossou, Camelia Protopopescu, Patrizia Carrieri, Laurence Camoin-Jau, Jean-Louis Mege, Didier Raoult
Q fever is a neglected and potentially fatal disease. During acute Q fever, antiphospholipid antibodies are very prevalent and have been associated with fever, thrombocytopenia, acquired heart valve disease, and progression to chronic endocarditis. However, thrombosis, the main clinical criterion of the 2006 updated classification of the antiphospholipid syndrome, has not been assessed in this context. To test whether thrombosis is associated with antiphospholipid antibodies and whether the criteria for antiphospholipid syndrome can be met in patients with acute Q fever, we conducted a cross-sectional study at the French National Referral Center for Q fever...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28723786/risk-factors-of-lymph-node-metastasis-in-lung-squamous-cell-carcinoma-of-3%C3%A2-cm-or-less-in-diameter
#5
Lijian Huang, Wenshan Li, Lufeng Zhao, Baizhou Li, Ying Chai
Through literature review we cannot find an efficient risk factor of lymph node metastasis in lung squamous cell carcinoma (SCC). This study aimed to investigate the risk factors of pathological lymph node status in patients with lung SCC of 3 cm or less in diameter, to provide some reference for the fellow surgeons in the decision of operative option.In total, we analyzed 154 patients with lung SCC of 3 cm or less in diameter who underwent lobectomy or bilobectomy or pneumonectomy with systematic lymph node dissection...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28723773/development-and-validation-of-risk-stratification-delirium-prediction-model-for-critically-ill-patients-a-prospective-observational-single-center-study
#6
Yu Chen, Hang Du, Bao-Hua Wei, Xue-Ni Chang, Chen-Ming Dong
The objective is to develop a model based on risk stratification to predict delirium among adult critically ill patients and whether early intervention could be provided for high-risk patients, which could reduce the incidence of delirium.We designed a prospective, observational, single-center study. We examined 11 factors, including age, APACHE-II score, coma, emergency operation, mechanical ventilation (MV), multiple trauma, metabolic acidosis, history of hypertension, delirium and dementia, and application of Dexmedetomidine Hydrochloride...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28723763/the-diagnostic-value-of-assays-for-circulating-tumor-cells-in-hepatocellular-carcinoma-a-meta-analysis
#7
Chi Sun, Wenjun Liao, Zefu Deng, Enliang Li, Qian Feng, Jun Lei, Rongfa Yuan, Shubing Zou, Yilei Mao, Jianghua Shao, Linquan Wu, Chao Zhang
PURPOSE: Circulating tumor cells (CTCs) are considered potential biomarkers for the detection of hepatocellular carcinoma (HCC). Many studies have attempted to explore this role, but the results are variable. We conducted the first comprehensive meta-analysis to evaluate the diagnostic value of CTC assay for HCC patients. Additional prognostic value was also assessed. EXPERIMENTAL DESIGN: All articles included in our study were assessed using QUADAS guidelines after a literature search...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28723709/delivering-prep-to-pregnant-and-breastfeeding-women-in-sub-saharan-africa-the-implementation-science-frontier
#8
Dvora L Joseph Davey, Linda-Gail Bekker, Pamina Gorbach, Thomas Coates, Landon Myer
: HIV acquisition during pregnancy and postpartum periods remains high despite increased access to and initiation of antiretroviral therapy in sub-Saharan Africa. Moreover, maternal seroconversion during pregnancy and breastfeeding remains a source of significant paediatric HIV infection in the region. In order to curb vertical HIV transmission, HIV acquisition during pregnancy and lactation must significantly decline. Biological and behavioural factors contribute to high HIV incidence, including hormonal changes that alter genital mucosal surfaces, and frequent condomless sex with HIV-infected partners or partners of unknown serostatus...
July 18, 2017: AIDS
https://www.readbyqxmd.com/read/28723228/thermal-processing-of-live-bivalve-molluscs-for-controlling-viruses-on-the-need-for-a-risk-based-design
#9
Winy Messens, Pablo S Fernandez-Escamez, David Lees, Roland Lindqvist, Michael O'Mahony, Elisabetta Suffredini, José Cortiñas Abrahantes, Emmanouil Chantzis, Kostas Koutsoumanis
Norovirus (NoV) and Hepatitis A virus (HAV) are the most important viral hazards associated with human illness following consumption of contaminated bivalve molluscs. The effectiveness of the current EU criteria for heat processing of bivalve molluscs (i.e. raising the temperature of the internal mollusc flesh to at least 90°C for a minimum of 90 seconds) was evaluated using predictive microbiology. A HAV thermal inactivation model was developed based on literature data in mollusc matrices during isothermal heat treatment...
July 19, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28722659/combing-nlr-v20-and-mean-lung-dose-to-predict-radiation-induced-lung-injury-in-patients-with-lung-cancer-treated-with-intensity-modulated-radiation-therapy-and-chemotherapy
#10
Wen-Yan Pan, Chao Bian, Guan-Lian Zou, Cui-Ying Zhang, Ping Hai, Ren Zhao, Yan-Yang Wang
The purpose was to evaluate the predictive value of baseline neutrophil to lymphocyte ratio (NLR) level in the incidence of grade 3 or higher radiation induced lung injury (RILI) for lung cancer patients. A retrospectively analysis with 166 lung cancer patients was performed. All of the enrolled patients received chemoradiotherapy at our hospital between April 2014 and May 2016. The Cox proportional hazard model was used to identify the potential risk factors for RILI. In this cohort, the incidence of grade 3 or higher RILI was 23...
July 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28722632/pilot-intervention-study-of-household-ventilation-and-fine-particulate-matter-concentrations-in-a-low-income-urban-area-dhaka-bangladesh
#11
Anne M Weaver, Shahana Parveen, Doli Goswami, Christina Crabtree-Ide, Carole Rudra, Jihnhee Yu, Lina Mu, Alicia M Fry, Iffat Sharmin, Stephen P Luby, Pavani K Ram
Fine particulate matter (PM2.5) is a risk factor for pneumonia; ventilation may be protective. We tested behavioral and structural ventilation interventions on indoor PM2.5 in Dhaka, Bangladesh. We recruited 59 good ventilation (window or door in ≥ 3 walls) and 29 poor ventilation (no window, one door) homes. We monitored baseline indoor and outdoor PM2.5 for 48 hours. We asked all participants to increase ventilation behavior, including opening windows and doors, and operating fans. Where permitted, we installed windows in nine poor ventilation homes, then repeated PM2...
May 30, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28722466/assessing-the-generalizability-of-the-national-lung-screening-trial-comparison-of-stage-1-patients
#12
Nichole T Tanner, Lin Dai, Brett C Bade, Mulugeta Gebregziabher, Gerard A Silvestri
RATIONALE: The findings of the National Lung Screening Trial (NLST) is the basis for screening high risk individuals based on age and smoking history. While screening is covered for eligible Medicare beneficiaries, the generalizability of the NLST in the elderly population has been questioned. OBJECTIVE: Compare outcomes of patients diagnosed with stage 1 non-small cell lung cancer(NSCLC) in the NLST to a nationally representative cohort of elderly patients Methods: Analysis of SEER-Medicare and NLST datasets for stage 1 patients ages 65-74 Measurements and Main Results: Lung cancer-specific mortality, all-cause mortality, and 30-60-90 day treatment mortality were measured...
July 19, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28722339/structured-pain-management-reduces-patient-discomfort-after-catheter-ablation-and-rhythm-device-surgery
#13
M Dörschner, A Bollmann, B Dinov, S Richter, M Döring, A Arya, A Müssigbrodt, S Kircher, N Dagres, P Sommer, G Hindricks, K Bode
BACKGROUND: The goal was to test the effectiveness of a structured pain management programme after invasive electrophysiological interventions in cardiology including ablation of atrial fibrillation (AF) or ventricular tachycardia (VT) and implantation, or explantation, of pacemakers or implantable cardioverter defibrillators. METHODS: This was a prospective study with a pre-/post-design where a post-intervention group (116 consecutive patients) was compared to a pre-intervention group (102 consecutive patients) after implementation of a structured pain-management programme using the numeric rating scale (NRS 0-10) and classified as moderate-to-severe if NRS > 3...
July 18, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28722293/robotic-assisted-percutaneous-coronary-intervention
#14
Daniel R Mangels, Jay Giri, John Hirshfeld, Robert L Wilensky
Performance of percutaneous coronary intervention (PCI) is associated with several occupational hazards including radiation exposure and musculoskeletal injury. Current methods to mitigate these risks range from suspended radiation suits to adjustable lead-lined glass shields. Robotic-assisted PCI is a novel approach to PCI that utilizes remote-controlled technology to manipulate catheters thereby significantly reducing radiation exposure to the operator and catheterization laboratory staff. Although limited, current evidence indicates that robotic-assisted PCI is associated with a high technical success rate and may have additional advantages over conventional PCI, such as a decreased incidence of geographical miss...
July 19, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28722210/plasma-microrna-based-signatures-to-predict-3-year-postoperative-recurrence-risk-for-stage-ii-and-iii-gastric-cancer
#15
Xinyang Liu, Xiaowei Zhang, Zhe Zhang, Jinjia Chang, Zhichao Wang, Zheng Wu, Chenchen Wang, Zuojun Sun, Xiaoxiao Ge, Ruixuan Geng, Wenbo Tang, Congqi Dai, Ying Lin, Fengjuan Lin, Menghong Sun, Weihua Jia, Wenqiong Xue, Jiafu Ji, Ying Hu, Guoyou Qin, Jin Li
Our aim was to identify plasma microRNA (miRNA)-based signatures to predict 3-year postoperative recurrence risk for patients with stage II and III gastric cancer (GC) so as to provide insights for individualized adjuvant therapy. Plasma miRNA expression was investigated in three phases, involving 407 patients recruited from three centers. ABI miRNA microarray and TaqMan Low Density Array were adopted in the discovery phase to identify potential miRNAs. Quantitative reverse-transcriptase polymerase chain reaction was used to assess the expression of selected miRNAs...
July 19, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28722086/-current-surgical-strategy-of-locally-recurrent-rectal-cancer
#16
Xin Wang, Yong Jiang
The incidence of locally recurrent rectal cancer (LRRC) is less than 10% following treatment for primary rectal cancer, while LRRC usually has serious symptoms and a very low survival rate when lack of treatment. For further efficacy improvement of LRRC operation, recent research topics include preoperative precise evaluation, correct decision, reasonable individual treatment by multidisciplinary collaboration. Surgery remains the only option for potential cure. Studies show R0 resection is the most important prognostic factor...
July 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28722080/-a-surgery-oriented-classification-in-conversion-therapy-of-gastric-cancer
#17
Ziyu Li, Kan Xue, Jiafu Ji
Clinical practice showed that some advanced gastric cancer (AGC) patients achieved long-term survival after surgery, whereas some benefited from non-surgical treatment. In recent years, with the emergence of new drugs, diversity of treatment and development of multi-disciplinary team, the concept of conversion therapy comes into attention. Owing to diverse phenotypes with scattered cases, publications are mainly case reports or small sample studies from single centers, which makes it hard to acquire high-level evidence...
July 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28721884/dosimetric-predictors-of-patient-reported-xerostomia-and-dysphagia-with-deintensified-chemoradiation-therapy-for-hpv-associated-oropharyngeal-squamous-cell-carcinoma
#18
Bhishamjit S Chera, David Fried, Alex Price, Robert J Amdur, William Mendenhall, Chiray Lu, Shiva Das, Nathan Sheets, Lawrence Marks, Panayiotis Mavroidis
PURPOSE/OBJECTIVE(S): To estimate the association between different dose-volume metrics of the salivary glands and pharyngeal constrictors with patient reported severity of xerostomia/dysphagia in the setting of deintensified chemoradiation therapy (CRT). METHODS AND MATERIALS: Forty-five patients were treated on a phase 2 study assessing the efficacy of deintensified CRT for favorable-risk, HPV-associated oropharyngeal squamous cell carcinoma. Patients received 60 Gy intensity modulated radiation therapy with concurrent weekly cisplatin (30 mg/m(2)), and reported the severity of their xerostomia/dysphagia (before and after treatment) using the patient-reported outcome version of the Common Terminology Criteria for Adverse Events (CTCAE) (PRO-CTCAE)...
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28721796/managing-patients-anxiety-about-planned-medical-interventions
#19
Bob Price
Patients are often anxious about planned medical interventions, and those experiencing anxiety are less likely to have the confidence to collaborate with healthcare professionals on their plan of care, and make decisions about consent. They may also find it challenging to follow rehabilitation guidelines, which can affect their long-term recovery. As part of their professional duty, nurses are required to recognise when people are anxious or in distress and respond compassionately, and while acquiring valid consent for any planned medical intervention requires the nurse to explain any risks, they should also attempt to reassure patients...
July 19, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28721634/minimally-invasive-abdominal-cerclage-compared-to-laparotomy-a-comparison-of-surgical-and-obstetric-outcomes
#20
Soorin Kim, Amanda Hill, Gulden Menderes, Sarah Cross, Masoud Azodi, Mert Ozan Bahtiyar
The objective of this study is to report surgical and obstetric outcomes of patients following abdominal cerclage placement through either minimally invasive or open techniques. Subjects of this retrospective cohort study were patients at two referral centers specializing in high-risk pregnancy and minimally invasive gynecologic surgery. Electronic medical records of all patients who underwent abdominal cerclage placement between December 2011 and December 2015 at Yale New Haven Hospital and Bridgeport Hospital were reviewed...
July 18, 2017: Journal of Robotic Surgery
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