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https://www.readbyqxmd.com/read/28640264/counterfeit-drugs-fight-fake-reagents-with-digital-tools
#1
Don Gunasekera
No abstract text is available yet for this article.
June 21, 2017: Nature
https://www.readbyqxmd.com/read/28637625/counterfeit-drugs-a-plot-worthy-of-john-le-carr%C3%A3
#2
EDITORIAL
Raymond L Woosley, Peter J Schwartz
No abstract text is available yet for this article.
June 18, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28633634/the-development-and-appraisal-of-a-tool-designed-to-find-patients-harmed-by-falsely-labelled-falsified-counterfeit-medicines
#3
Marija Anđelković, Einar Björnsson, Virgilio De Bono, Nenad Dikić, Katleen Devue, Daniel Ferlin, Miroslav Hanževački, Freyja Jónsdóttir, Mkrtich Shakaryan, Sabine Walser
BACKGROUND: Falsely labelled, falsified (counterfeit) medicines (FFCm's) are produced or distributed illegally and can harm patients. Although the occurrence of FFCm's is increasing in Europe, harm is rarely reported. The European Directorate for the Quality of Medicines & Health-Care (EDQM) has therefore coordinated the development and validation of a screening tool. METHODS: The tool consists of a questionnaire referring to a watch-list of FFCm's identified in Europe, including symptoms of their use and individual risk factors, and a scoring form...
June 20, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28631113/fast-determination-of-ingredients-in-solid-pharmaceuticals-by-microwave-enhanced-in-source-decay-of-microwave-plasma-torch-mass-spectrometry
#4
Rui Su, Xinchen Wang, Changming Hou, Meiling Yang, Keke Huang, Huanwen Chen
Rapid qualitative and quantitative analysis of solid samples (e.g., pharmaceutical preparations) by using a small and low-resolution mass spectrometer without MS/MS function is still a challenge in ambient pressure ionization mass spectrometric analysis. Herein, a practically efficient method termed microwave-enhanced in-source decay (MEISD) using microwave plasma torch desorption ionization coupled with time-of-flight mass spectrometry (MPTDI-TOF MS) was developed for fast analysis of pharmaceutical tablets using a miniature TOF mass spectrometer without tandem mass function...
June 19, 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28625144/detection-of-poor-quality-artemisinin-based-combination-therapy-act-medicines-marketed-in-benin-using-simple-and-advanced-analytical-techniques
#5
Achille Yemoa, Védaste Habyalimana, Jérémie K Mbinze, Victoria Crickboom, Benjamin Muhigirwa, Agnès Ngoya, Pierre-Yves Sacré, Fernand Gbaguidi, Joëlle Quetin-Leclercq, Philippe Hubert, Roland D Marini
BACKGROUND: Poor quality antimalarial medicines still represent a threat to the public health, especially in Sub-Saharan Africa who bears a disproportionate share of the global burden of malaria. It is essential and urgent to strengthen mechanisms against counterfeit medicines. One of the approaches is regular market surveillance through quality controls. METHODS: 12 samples of artemether/lumefantrine were collected from formal and informal drug sellers in Cotonou (Benin) as well as additional other similar samples from Rwanda (13 samples) and from D...
June 15, 2017: Current Drug Safety
https://www.readbyqxmd.com/read/28624673/a-geographical-analysis-of-trafficking-on-a-popular-darknet-market
#6
Julian Broséus, Damien Rhumorbarbe, Marie Morelato, Ludovic Staehli, Quentin Rossy
Cryptomarkets are online marketplaces, located on the darknet, that facilitate the trading of a variety of illegal goods, mostly drugs. While the literature essentially focus on drugs, various other goods and products related to financial or identity fraud, firearms, counterfeit goods, as well as doping products are also offered on these marketplaces. Through the analysis of relevant data collected on a popular marketplace in 2014-2015, Evolution, this research provides an analysis of the structure of trafficking (types and proportions of products, number of vendors and shipping countries)...
June 4, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28621556/exposure-to-sexual-stimuli-induces-greater-discounting-leading-to-increased-involvement-in-cyber-delinquency-among-men
#7
Wen Cheng, Wen-Bin Chiou
People frequently encounter sexual stimuli during Internet use. Research has shown that stimuli inducing sexual motivation can lead to greater impulsivity in men, as manifested in greater temporal discounting (i.e., a tendency to prefer smaller, immediate gains to larger, future ones). Extant findings in crime research suggest that delinquents tend to focus on short-term gains while failing to adequately think through the longer-term consequences of delinquent behavior. We experimentally tested the possibility that exposure to sexual stimuli is associated with the tendency to engage in cyber delinquency among men, as a result of their overly discounting remote consequences...
June 16, 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28606338/forensic-intelligence-applied-to-questioned-document-analysis-a-model-and-its-application-against-organized-crime
#8
Josep De Alcaraz-Fossoul, Katherine A Roberts
The capability of forensic sciences to fight crime, especially against organized criminal groups, becomes relevant in the recent economic downturn and the war on terrorism. In view of these societal challenges, the methods of combating crime should experience critical changes in order to improve the effectiveness and efficiency of the current resources available. It is obvious that authorities have serious difficulties combating criminal groups of transnational nature. These are characterized as well structured organizations with international connections, abundant financial resources and comprised of members with significant and diverse expertise...
July 2017: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/28606335/atr-ftir-characterization-of-generic-brand-named-and-counterfeit-sildenafil-and-tadalafil-based-tablets-found-on-the-brazilian-market
#9
José Coelho Neto, Fernanda L C Lisboa
Viagra and Cialis are among the most counterfeited medicines in many parts of the world, including Brazil. Despite the many studies that have been made regarding discrimination between genuine and counterfeit samples, most published works do not contemplate generic and similar versions of these medicines and also do not explore excipients/adjuvants contributions when characterizing genuine and suspected samples. In this study, we present our findings in exploring ATR-FTIR spectral profiles for characterizing both genuine and questioned samples of several generic and brand-name sildenafil- and tadalafil-based tablets available on the Brazilian market, including Viagra and Cialis...
July 2017: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/28605074/covert-photonic-barcodes-based-on-light-controlled-acidichromism-in-organic-dye-doped-whispering-gallery-mode-microdisks
#10
Zhenhua Gao, Cong Wei, Yongli Yan, Wei Zhang, Haiyun Dong, Jinyang Zhao, Jun Yi, Chunhuan Zhang, Yong Jun Li, Yong Sheng Zhao
Photonic barcodes with a small footprint have demonstrated a great value for multiplexed high-throughput bioassays and tracking systems. Attempts to develop coding technology tend to focus on the generation of featured barcodes both with high coding capacity and accurate recognition. In this work, a strategy to design photonic barcodes is proposed based on whispering-gallery-mode (WGM) modulations in dye-doped microdisk resonant cavities, where each modulated photoluminescence spectrum constitutes the fingerprint of a corresponding microdisk...
June 12, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28598163/structural-color-patterns-on-paper-fabricated-by-inkjet-printer-and-their-application-in-anti-counterfeiting
#11
Suli Wu, Baoqi Liu, Xin Su, Shufen Zhang
Inkjet printed structural color patterns have attracted great attention in recent years because of their broadly promising applications. However, the patterns are usually fabricated on pre-treated plastic substrates. Herein a convenient inkjet printing method was developed to fabricate large scale computer designed structural color patterns on photo paper without any treatment using inks containing monodisperse CdS spheres. By this strategy, not only the single color and multi-color structural color patterns on paper were successfully obtained, but also invisible photonic anti-counterfeiting was achieved without any external stimuli...
June 9, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28590391/misuse-of-novel-synthetic-opioids-a-deadly-new-trend
#12
Matthew P Prekupec, Peter A Mansky, Michael H Baumann
: Novel synthetic opioids (NSOs) include various analogs of fentanyl and newly emerging non-fentanyl compounds. Together with illicitly manufactured fentanyl (IMF), these drugs have caused a recent spike in overdose deaths, whereas deaths from prescription opioids have stabilized. NSOs are used as stand-alone products, as adulterants in heroin, or as constituents of counterfeit prescription medications. During 2015 alone, there were 9580 deaths from synthetic opioids other than methadone. Most of these fatalities were associated with IMF rather than diverted pharmaceutical fentanyl...
June 5, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28576314/multivariate-analysis-of-scotch-whisky-by-total-reflection-x-ray-fluorescence-and-chemometric-methods-a-potential-tool-in-the-identification-of-counterfeits
#13
Charles A Shand, Renate Wendler, Lorna Dawson, Kyari Yates, Hayleigh Stephenson
Most methods used in the identification of counterfeit whisky have focused on the profiling of volatile organic congeners determined by gas chromatography. We tested the use of total reflection x-ray fluorescence (TXRF) for trace element analysis of whisky and application of the data as a potential tool in the identification of counterfeit samples. Twenty five whiskies that were produced in different regions of Scotland or were blends, 5 counterfeit whiskies, 1 unmatured grain whisky, and 1 matured grain whisky were analysed for 11 elements (P, S, Cl, K, Ca, Mn, Fe, Cu, Zn, Br and Rb)...
July 11, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28572433/the-counterfeiters-by-andr%C3%A3-gide-psychiatry-in-literature
#14
Alistair Stewart
No abstract text is available yet for this article.
June 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28569319/employing-shells-to-eliminate-concentration-quenching-in-photonic-upconversion-nanostructure
#15
Jing Zuo, Qiqing Li, Bin Xue, Cuixia Li, Yulei Chang, Youlin Zhang, Xiaomin Liu, Langping Tu, Hong Zhang, Xianggui Kong
It is generally accepted that a lanthanide ions based upconversion material follows an activator low doping strategy (normally <3 mol%), because of the restriction of the harmful concentration quenching effect. Here, we demonstrate that this limitation can be broken in nanostructures. Simply by using an inert shell coating strategy, the concentration quenching effect for the activator (Er(3+)) could be eliminated and highly efficient upconversion luminescence realized in the activator fully doped nanostructure, e...
June 1, 2017: Nanoscale
https://www.readbyqxmd.com/read/28559845/combating-sale-of-counterfeit-and-falsified-medicines-online-a-losing-battle
#16
Kah Seng Lee, Siew Mei Yee, Syed Tabish Razi Zaidi, Rahul P Patel, Quan Yang, Yaser Mohammed Al-Worafi, Long Chiau Ming
No abstract text is available yet for this article.
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28549909/poor-quality-and-counterfeit-drugs-a-systematic-assessment-of-prevalence-and-risks-based-on-data-published-from-2007-2016
#17
Andreas Koczwara, Jennifer Dressman
Counterfeit drugs can hurt patients and harm the pharmaceutical industry. In 2006, the International Medical Products Anti-Counterfeiting Taskforce expressed a need to generate more and better data to calculate a worldwide prevalence of counterfeiting. This review analyzes field test data that were published in the time-frame January 2007 to December 2016, were accessible via Pubmed, and which addressed the prevalence of counterfeit drugs. Based on the 41 studies identified, it is still not possible to make a reliable statement about the prevalence of counterfeit drugs due to the heterogeneity of the results...
May 23, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28549854/an-empirical-review-of-antimalarial-quality-field-surveys-the-importance-of-characterising-outcomes
#18
REVIEW
James Grech, James Robertson, Jackson Thomas, Gabrielle Cooper, Mark Naunton, Tamsin Kelly
For decades, thousands of people have been dying from malaria infections because of poor-quality medicines (PQMs). While numerous efforts have been initiated to reduce their presence, PQMs are still risking the lives of those seeking treatment. This review addresses the importance of characterising results of antimalarial medicine field surveys based upon the agreement of clearly defined definitions. Medicines found to be of poor quality can be falsified or counterfeit, substandard or degraded. The distinction between these categories is important as each category requires a different countermeasure...
May 8, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28542816/identification-of-microorganisms-isolated-from-counterfeit-and-unapproved-decorative-contact-lenses
#19
Adrian D Land, Katie L Penno, Jennifer L Brzezinski
All contact lenses (corrective/noncorrective) are considered Class II or Class III medical devices under the Federal Food, Drug, and Cosmetic Act, which also states that contact lenses can only be obtained with a prescription. The Forensic Chemistry Center of the US Food & Drug Administration has examined over 300 decorative, noncorrective contact lenses obtained without a prescription. Our observations indicate that 60% of the counterfeit lenses and 27% of the unapproved lenses examined were positive for microbial contamination...
May 24, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28525909/counterfeit-pennies-distinguishing-chromoblastomycosis-from-phaeohyphomycotic-infections
#20
Hadas Skupsky, Jacqueline Junkins-Hopkins
No abstract text is available yet for this article.
June 2017: American Journal of Dermatopathology
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