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https://www.readbyqxmd.com/read/29052964/brief-interactive-psychoeducation-for-caregivers-of-patients-with-early-phase-psychosis-in-yogyakarta-indonesia
#1
Carla R Marchira, Irwan Supriyanto, Subandi Subandi, Mary Jo D Good, Byron J Good
AIM: Brief psychoeducation for families of psychotic patients has been shown to significantly increase family members' knowledge of the disorder. This increase is associated with reductions in relapse and rehospitalization. The aim of this study was to assess the effectiveness of brief psychoeducation about schizophrenia to caregivers of patients in early phases of psychotic disorders in Yogyakarta, Indonesia. METHODS: This study was a prospective, randomized trial with 2 parallel groups...
October 20, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29045304/effect-of-clozapine-vs-other-second-generation-antipsychotics-on-hospitalization-and-seclusion-a-retrospective-mirror-image-study-in-a-japanese-public-psychiatric-hospital
#2
Fuminari Misawa, Takefumi Suzuki, Yasuo Fujii
BACKGROUND: Clozapine has been regarded as the gold standard for patients with treatment-resistant schizophrenia, but a recent network meta-analysis has questioned its relative superiority over other second-generation antipsychotics (SGAs) such as olanzapine and risperidone. PURPOSE: We conducted a retrospective mirror-image study of clozapine vs other SGAs to evaluate real-world effectiveness of clozapine in terms of the duration of hospitalization and seclusion, both of which represent a critical outcome...
October 17, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29042823/digital-health-technology-for-use-in-patients-with-serious-mental-illness-a-systematic-review-of-the-literature
#3
REVIEW
Sonal Batra, Ross A Baker, Tao Wang, Felicia Forma, Faith DiBiasi, Timothy Peters-Strickland
BACKGROUND: As the capabilities and reach of technology have expanded, there is an accompanying proliferation of digital technologies developed for use in the care of patients with mental illness. The objective of this review was to systematically search published literature to identify currently available health technologies and their intended uses for patients with serious mental illness. MATERIALS AND METHODS: The Medline, Embase, and BIOSIS Previews electronic databases were searched to identify peer-reviewed English language articles that reported the use of digital, mobile, and other advanced technology in patients with schizophrenia/schizoaffective disorder, bipolar disorder, and major depressive disorder...
2017: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/29024893/plasma-ratio-of-clozapine-to-n-desmethylclozapine-can-predict-cognitive-performance-in-treatment-resistant-psychotic-patients
#4
Conrad Molins, Mar Carceller-Sindreu, Helena Navarro, Cristina Carmona, Marina Piñeiro, Estrella Martínez, Enric Álvarez, Maria J Portella
Cognitive symptoms play a central role in schizophrenia and are strongly associated with social functioning. Treatment with clozapine presents controversial results regarding its effects on cognition. The opposite effects of clozapine and n-desmethylclozapine (NDMC) on cholinergic system have been suggested to underlie these inconclusive findings. The aim of this study is to determine whether clozapine/NDMC ratio can predict cognitive performance in patients with treatment-resistant psychosis. Nineteen clinically stable patients with schizophrenia or schizoaffective disorder treated with clozapine monotherapy completed demographic and clinical interviews...
October 3, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29021925/acetazolamide-treatment-of-psychogenic-polydipsia
#5
Syed E Ahmed, Afaque H Khan
We are reporting a case of psychogenic polydipsia from a State of Ohio psychiatric hospital. The patient has a known five-year history of psychogenic polydipsia with recurrent hyponatremia and has been diagnosed with schizoaffective disorder bipolar type 1, according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria, for the past two decades. There was a marked improvement with the use of acetazolamide, resulting in a decreased compulsion to drink fluid and improvement of his hyponatremia...
August 9, 2017: Curēus
https://www.readbyqxmd.com/read/29018549/perceptions-and-knowledge-of-antipsychotics-among-mental-health-professionals-and-patients
#6
Lindah Cahling, Anders Berntsson, Gabriella Bröms, Lars Öhrmalm
Aims and method To assess the patients' most influential concerns regarding long-acting injectable antipsychotics (LAIs) and mental health professionals' preconceptions about these concerns. For both groups, to assess the level of knowledge about LAIs. This cross-sectional study used semi-structured interviews of patients with schizophrenia or schizoaffective disorder (n = 164), nurses (n = 43) and physicians (n = 20). Results The mental health professionals overestimated many of the patients' fears of LAIs, and the expressed fears exceeded the actual experiences of patients already on LAIs...
October 2017: BJPsych Bulletin
https://www.readbyqxmd.com/read/28987077/remission-of-schizoaffective-disorder-using-homeopathic-medicine-2-case-reports
#7
Diane E Grise, Tara Peyman, Jeffrey Langland
Context • Research on the schizophrenia spectrum is primarily focused on pharmaceutical interventions, although alternative treatments have been gaining increasing popularity in recent years because patients are seeking treatments that are effective and have reduced side effects. A significant body of evidence already exists supporting the effectiveness of homeopathy to treat a wide array of illnesses. Objective • The research team intended to demonstrate the need for using both alternative and conventional treatments to improve clinical outcomes in the treatment of schizoaffective disorder...
October 2, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28981913/olfactory-functioning-in-first-episode-psychosis
#8
Vidyulata Kamath, Patricia Lasutschinkow, Koko Ishizuka, Akira Sawa
BACKGROUND: Though olfactory deficits are well-documented in schizophrenia, fewer studies have examined olfactory performance profiles across the psychosis spectrum. The current study examined odor identification, discrimination, and detection threshold performance in first-episode psychosis (FEP) patients diagnosed with schizophrenia, schizoaffective disorder, bipolar disorder with psychotic features, major depression with psychotic features, and other psychotic conditions. METHOD: FEP patients (n = 97) and healthy adults (n = 98) completed birhinal assessments of odor identification, discrimination, and detection threshold sensitivity for lyral and citralva...
August 31, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28981832/cognitive-predictors-of-work-among-social-security-disability-insurance-beneficiaries-with-psychiatric-disorders-enrolled-in-ips-supported-employment
#9
Susan R McGurk, Robert E Drake, Haiyi Xie, Jarnee Riley, Roline Milfort, Thomas W Hale, William Frey
BACKGROUND: Impaired cognitive functioning is a significant predictor of work dysfunction in schizophrenia. Less is known, however about relationships of cognition and work in people with less severe disorders with relatively normal cognitive functioning. METHODS: This secondary analysis evaluated cognitive predictors of work in Social Security Disability Insurance (SSDI) beneficiaries with a recent work history who were randomized to receive mental health services, supported employment, and freedom from work disincentives over a 2-year study period in the Mental Health Treatment Study...
August 31, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28981831/widespread-volumetric-reductions-in-schizophrenia-and-schizoaffective-patients-displaying-compromised-cognitive-abilities
#10
Tamsyn E Van Rheenen, Vanessa Cropley, Andrew Zalesky, Chad Bousman, Ruth Wells, Jason Bruggemann, Suresh Sundram, Danielle Weinberg, Roshel K Lenroot, Avril Pereira, Cynthia Shannon Weickert, Thomas W Weickert, Christos Pantelis
OBJECTIVE: Progress toward understanding brain mechanisms in psychosis is hampered by failures to account for within-group heterogeneity that exists across neuropsychological domains. We recently identified distinct cognitive subgroups that might assist in identifying more biologically meaningful subtypes of psychosis. In the present study, we examined whether underlying structural brain abnormalities differentiate these cognitively derived subgroups. METHOD: 1...
August 21, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28981811/prospective-relationships-between-motivation-and-functioning-in-recovery-after-a-first-episode-of-schizophrenia
#11
Daniel Fulford, Danijela Piskulic, Jean Addington, John M Kane, Nina R Schooler, Kim T Mueser
Diminished motivation is associated with robust impairment in psychosocial functioning in schizophrenia (SZ). Little is known about the reciprocal relationships between motivation and functioning, particularly following a first episode of psychosis. We tested bidirectional associations between motivation and social and occupational functioning in the year following a first episode of SZ spectrum disorder among patients in the Recovery After an Initial Schizophrenia Episode-Early Treatment Program (RAISE-ETP) study...
August 18, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28967321/psychological-distress-among-caregivers-of-individuals-with-a-diagnosis-of-schizophrenia-or-schizoaffective-disorder
#12
Debra Lerner, Hong Chang, William H Rogers, Carmela Benson, Mercedes C Lyson, Lisa B Dixon
OBJECTIVE: The aim was to quantify caregiver distress among informal caregivers of individuals with schizophrenia or schizoaffective disorder and identify its correlates. METHODS: From December 2014 through April 2015, ads posted with mental health advocates and the media recruited informal caregivers, age ≥21 years, to complete an online questionnaire. It included the ten-item Perceived Stress Scale (PSS) (0, no distress; 39, highest) and hypothesized distress correlates in four groups: caregiver and care recipient characteristics; caregiver role demands; caregiver social supports; and caregiver cognitive appraisals of caregiving...
October 2, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28965532/pharmacogenetic-testing-for-the-guidance-of-psychiatric-treatment-of-a-schizoaffective-patient-with-haltlose-personality-disorder
#13
João Gama Marques
No abstract text is available yet for this article.
October 2, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28953804/guidelines-for-individual-and-group-psychodynamic-psychotherapy-for-the-treatment-of-persons-diagnosed-with-psychosis-and-or-schizophrenia
#14
Slađana Štrkalj Ivezić, Branka Restek Petrović, Ivan Urlić, Majda Grah, Nina Mayer, Dubravka Stijačić, Tihana Jendričko, Sanja Martić-Biočina
The hereby presented guidelines for the use of psychodynamic psychotherapy are based on references and research in the field of individual and group therapy and they refer to psychotherapy for patients suffering from the first psychotic episode, schizophrenia, schizoaffective psychosis, bipolar disorder and paranoid psychosis. The aim was to provide an overview of present literature and to give recommendations based on current knowledge. Clinical experience and research of the outcomes of psychodynamic psychotherapy encourage positioning of such treatments among recommendations for treating various mental disorders, as well as in the field of psychotherapy of patients with psychotic disorders (PD)...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28948424/feasibility-acceptability-and-preliminary-effectiveness-of-a-peer-delivered-and-technology-supported-self-management-intervention-for-older-adults-with-serious-mental-illness
#15
Karen L Fortuna, Peter R DiMilia, Matthew C Lohman, Martha L Bruce, Cynthia D Zubritsky, Mitch R Halaby, Robert M Walker, Jessica M Brooks, Stephen J Bartels
To assess the feasibility, acceptability, and preliminary effectiveness of a peer-delivered and technology supported integrated medical and psychiatric self-management intervention for older adults with serious mental illness. Ten older adults with serious mental illness (i.e., schizophrenia, schizoaffective disorder, bipolar disorder, or major depressive disorder) and medical comorbidity (i.e., cardiovascular disease, obesity, diabetes, chronic obstructive pulmonary disease, hypertension, and/or high cholesterol) aged 60 years and older received the PeerTECH intervention in their homes...
September 26, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28932600/abnormal-n400-semantic-priming-effect-may-reflect-psychopathological-processes-in-schizophrenia-a-twin-study
#16
Anuradha Sharma, Heinrich Sauer, Holger Hill, Claudia Kaufmann, Stephan Bender, Matthias Weisbrod
OBJECTIVE: Activation of semantic networks is indexed by the N400 effect. We used a twin study design to investigate whether N400 effect abnormalities reflect genetic/trait liability or are related to psychopathological processes in schizophrenia. METHODS: We employed robust linear regression to compare N400 and behavioral priming effects across 36 monozygotic twin pairs (6 pairs concordant for schizophrenia/schizoaffective disorder, 11 discordant pairs, and 19 healthy control pairs) performing a lexical decision task...
2017: Schizophrenia Research and Treatment
https://www.readbyqxmd.com/read/28926346/coprophagic-asphyxiation-in-an-intellectually-disabled-woman
#17
Stephanie LeeAnne Erickson, Aaron David Gambrell, James Fulcher, Michael Ward
The ingestion of one's own feces is referred to as coprophagia. In this report, the author discusses a case of coprophagia-associated death in a 36-year-old woman. The woman had a history of intellectual disability, bipolar disorder, and schizoaffective disorder and was living in a group home. At autopsy, examination of the upper airway revealed 4 distinct spherical boli of impacted fecal matter in the oral cavity and pharynx. Death was attributed to asphyxia due to aspiration of stool bolus during an episode of coprophagia...
September 19, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28923068/using-blood-cytokine-measures-to-define-high-inflammatory-biotype-of-schizophrenia-and-schizoaffective-disorder
#18
Danny Boerrigter, Thomas W Weickert, Rhoshel Lenroot, Maryanne O'Donnell, Cherrie Galletly, Dennis Liu, Martin Burgess, Roxanne Cadiz, Isabella Jacomb, Vibeke S Catts, Stu G Fillman, Cynthia Shannon Weickert
BACKGROUND: Increases in pro-inflammatory cytokines are found in the brain and blood of people with schizophrenia. However, increased cytokines are not evident in all people with schizophrenia, but are found in a subset. The cytokine changes that best define this subset, termed the "elevated inflammatory biotype", are still being identified. METHODS: Using quantitative RT-PCR, we measured five cytokine mRNAs (IL-1β, IL-2 IL-6, IL-8 and IL-18) from peripheral blood of healthy controls and of people with schizophrenia or schizoaffective disorder (n = 165)...
September 18, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/28918417/-clinical-features-of-psychotic-and-non-psychotic-bipolar-patients
#19
Zsuzsanna Belteczki, Zoltan Rihmer, Julia Ujvari
BACKGROUND: Psychotic symptoms are common in the case of manic, depressive and mixed episodes of bipolar disorder; however, the assessment of delusions and hallucinations is frequently improper, thus the patients presenting also psychotic symptoms are treated based on their diagnosis of schizophrenia, schizoaffective disorder or paranoia. Psychotic symptoms in bipolar disorder result less favourable outcomes and course of illness. METHODS: 365 patients (106 males, 259 females) were hospitalized in or institution from January 1st 2015 to September 30th 2016, who were diagnosed with bipolar disorder according to the ICD-10 criteria...
June 2017: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/28902459/exome-sequences-of-multiplex-multigenerational-families-reveal-schizophrenia-risk-loci-with-potential-implications-for-neurocognitive-performance
#20
Mark Z Kos, Melanie A Carless, Juan Peralta, Joanne E Curran, Ellen E Quillen, Marcio Almeida, August Blackburn, Lucy Blondell, David R Roalf, Michael F Pogue-Geile, Ruben C Gur, Harald H H Göring, Vishwajit L Nimgaonkar, Raquel E Gur, Laura Almasy
Schizophrenia is a serious mental illness, involving disruptions in thought and behavior, with a worldwide prevalence of about one percent. Although highly heritable, much of the genetic liability of schizophrenia is yet to be explained. We searched for susceptibility loci in multiplex, multigenerational families affected by schizophrenia, targeting protein-altering variation with in silico predicted functional effects. Exome sequencing was performed on 136 samples from eight European-American families, including 23 individuals diagnosed with schizophrenia or schizoaffective disorder...
September 13, 2017: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
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