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https://www.readbyqxmd.com/read/28525618/establishing-expanding-and-certifying-a-closed-colony-of-phlebotomus-argentipes-diptera-psychodidae-for-xenodiagnostic-studies-at-the-kala-azar-medical-research-center-muzaffarpur-bihar-india
#1
Puja Tiwary, Shakti Kumar Singh, Anurag Kumar Kushwaha, Edgar Rowton, David Sacks, Om Prakash Singh, Shyam Sundar, Phillip Lawyer
This pilot project was preliminary and essential to a larger effort to define the ability of certain human-subject groups across the infection spectrum to serve as reservoirs of Leishmania donovani infection to sand flies in areas of anthroponotic transmission such as in Bihar state, India. This is possible only via xenodiagnosis of well-defined subject groups using live vector sand flies. The objective was to establish at the Kala Azar Medical Research Center (KAMRC), Muzaffarpur, Bihar, India, a self-sustaining colony of Phlebotomus argentipes (Annandale & Brunneti), closed to infusion with wild-caught material and certified safe for human xenodiagnosis...
May 19, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28524239/oral-contraceptive-pills-risky-or-protective-in-case-of-trichinella-spiralis-infection
#2
Marwa A Hasby Saad, Dina A Radi, Eiman A Hasby
AIM: to investigate how Trichinella spiralis infection can be affected by contraceptive pills invivo. METHODS: included six groups of female Wistar rats; healthy, Trichinella infected, receiving combined contraceptive pills (COCPs), receiving progestin only pills (POPs), infected receiving COCPs and infected receiving POPs. Parasite burden was measured (two gender worm counts, gravidity, larvae/muscle and RCI). Histopathological examination, immunohistochemical detection of C-kit mast cells & Foxp3+ T-reg...
May 19, 2017: Parasite Immunology
https://www.readbyqxmd.com/read/28510071/surgical-techniques-for-open-fetal-repair-of-myelomeningocele
#3
Nalin Gupta
The current standard for fetal repair of myelomeningocele is an open exposure of the gravid uterus with control of the amniotic membranes, and then a multi-layer closure of the fetal defect. The nature of the surgical repair has evolved and requires a series of steps that take into account the delicate nature of the fetal tissues. The individual surgical steps are described including potential pitfalls.
May 16, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28505513/polyfluoroalkyl-substance-exposure-in-the-mid-ohio-river-valley-1991-2012
#4
Robert L Herrick, Jeanette Buckholz, Frank M Biro, Antonia M Calafat, Xiaoyun Ye, Changchun Xie, Susan M Pinney
BACKGROUND: Industrial discharges of perfluorooctanoic acid (PFOA) to the Ohio River, contaminating water systems near Parkersburg, WV, were previously associated with nearby residents' serum PFOA concentrations above US general population medians. Ohio River PFOA concentrations downstream are elevated, suggesting Mid-Ohio River Valley residents are exposed through drinking water. OBJECTIVES: Quantify PFOA and 10 other per- and polyfluoroalkyl substances (PFAS) in Mid-Ohio River Valley resident sera collected between 1991 and 2013 and determine whether the Ohio River and Ohio River Aquifer are exposure sources...
May 12, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28501362/mode-of-conception-does-not-appear-to-affect-placental-volume-in-the-first-trimester
#5
Sara J Churchill, Erica T Wang, Marcy Akhlaghpour, Ellen H Goldstein, Dina Eschevarria, Naomi Greene, Matthew Macer, Temeka Zore, John Williams, Margareta D Pisarska
OBJECTIVE: To study whether infertility treatments, including IVF and non-IVF fertility treatments, are associated with diseases of placental insufficiency in early gestation. First trimester placental volumes by ultrasound and chorionic villi weight during sampling (CVS) were performed to detect differences between pregnancies conceived spontaneously versus with fertility treatments. DESIGN: Retrospective cohort. SETTING: Academic tertiary center...
May 10, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28500814/fta-cards-facilitate-storage-shipment-and-detection-of-arboviruses-in-infected-aedes-aegypti-collected-in-adult-mosquito-traps
#6
Sonja Hall-Mendelin, Glen R Hewitson, Doris Genge, Peter J Burtonclay, Amanda J De Jong, Alyssa T Pyke, Andrew F van den Hurk
AbstractThe utility of applying infected Aedes aegypti to Flinders Technology Associates (FTA(®)) cards for storage, transport, and detection of dengue, Zika, and Barmah Forest viruses was assessed in laboratory-based experiments. The mosquitoes had been removed from Gravid Aedes Traps maintained under conditions of high temperature and humidity. RNA of all viruses could be detected in infected mosquitoes on FTA cards either individually or in pools with uninfected mosquitoes, and stored for up to 28 days...
May 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28498341/replication-of-high-fetal-alcohol-spectrum-disorders-prevalence-rates-child-characteristics-and-maternal-risk-factors-in-a-second-sample-of-rural-communities-in-south-africa
#7
Philip A May, Marlene M De Vries, Anna-Susan Marais, Wendy O Kalberg, David Buckley, Colleen M Adnams, Julie M Hasken, Barbara Tabachnick, Luther K Robinson, Melanie A Manning, Heidre Bezuidenhout, Margaret P Adam, Kenneth L Jones, Soraya Seedat, Charles D H Parry, H Eugene Hoyme
Background: Prevalence and characteristics of fetal alcohol syndrome (FAS) and total fetal alcohol spectrum disorders (FASD) were studied in a second sample of three South African rural communities to assess change. Methods: Active case ascertainment focused on children with height, weight and/or head circumference ≤25th centile and randomly-selected children. Final diagnoses were based on dysmorphology, neurobehavioral scores, and maternal risk interviews. Results: Cardinal facial features, head circumference, and total dysmorphology scores differentiated specific FASD diagnostic categories in a somewhat linear fashion but all FASD traits were significantly worse than those of randomly-selected controls...
May 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28494269/medical-conditions-associated-with-recurrent-miscarriage-is-bmi-the-tip-of-the-iceberg
#8
Mushi J Matjila, Anne Hoffman, Zephne M van der Spuy
BACKGROUND: In contrast to sporadic miscarriage, recurrent miscarriage (RM) is a rare entity which affects 1% of couples attempting conception. It is distressing for couples and healthcare professionals as the aetiology is unclear with limited treatment options. Apart from anti-phospholipid syndrome (APS), the strength of associations between RM and commonly investigated endocrine, autoimmune, thrombophilic and uterine structural abnormalities remains uncertain and variable. OBJECTIVES: To assess the prevalence of commonly investigated medical conditions associated with RM...
May 3, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28479738/prenatal-developmental-toxicity-study-of-glycosides-based-standardized-fenugreek-seed-extract-in-rats
#9
Pallavi O Deshpande, Vishwaraman Mohan, Mukul P Pore, Shailesh Gumaste, Prasad A Thakurdesai
CONTEXT: Glycoside-based standardized fenugreek seed extract (SFSE-G) demonstrated promising efficacy in animal models of immune-inflammatory conditions. AIM: The present study was aimed at embryo-fetal development toxicity evaluation of SFSE-G in Wistar rats as per guideline No. 414 of the Organization for Economic Co-operation and Development (OECD). MATERIAL AND METHODS: Mated female rats were randomized into four groups of 30 each and received oral doses of either SFSE-G at 250, 500, and 1000 mg/kg or vehicle (water) during the period of gestation (postconception) from gestational day 5 (GD5, an implantation day) until 1 day before cesarean sections (GD19)...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28474123/ct-pulmonary-angiogram-quality-comparison-between-early-and-later-pregnancy
#10
Yoel Siegel, Russ Kuker, James Banks, Gary Danton
PURPOSE: Pregnancy increases the risk for thromboembolic disease. CT pulmonary angiogram (CTPA) is widely used for the diagnosis of pulmonary embolus (PE); however, a significant number of scans are suboptimal or non-diagnostic in pregnant patients. This phenomenon is attributed to physiology during the gravid state. The aim of this study is to examine whether all stages of pregnancy are similarly at risk for suboptimal scans. METHODS: Pregnant patients who had CTPA scans between February 2008 and November 2014 were included...
May 4, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28472898/the-relation-among-steroid-hormone-levels-lipid-profile-and-menopausal-symptom-severity
#11
Cihan Kaya, Hüseyin Cengiz, Ali Yeşil, Murat Ekin, Levent Yaşar
INTRODUCTION: Many postmenopausal women experience hot flashes, night sweats, non-specific emotional and psychological distresses. Our aim was to investigate the relation among steroid hormone levels, lipid profile and menopausal symptom severity using the menopause rating scale (MRS). METHODS: A cross-sectional study was performed at our outpatient clinic with natural postmenopausal women. A total of 444 women were included in this study. The basic characteristics of the study population, such as age, gravidity, parity, time to menopause onset and body mass index (BMI) were recorded...
May 4, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28471125/the-association-between-clinical-parameters-and-uterine-fibroid-size-in-patients-who-underwent-abdominal-myomectomy
#12
Mehmet Çınar, Rıfat Taner Aksoy, Ali İrfan Güzel, Aytekin Tokmak, Okan Yenicesu, Esma Sarıkaya, Özlem Evliyaoğlu
OBJECTIVES: To evaluate if there is an association between neutrophil lymphocyte ratio and tumor markers in patients with uterine fibroids. METHODS: A total of three hundred and fifty seven patients who operated for myomectomy were enrolled this retrospective case control study. Risk factors evaluated were; age, uterine fibroid type, body mass index (BMI), gravidity, parity, preoperative and postoperative hemoglobin difference, neutrophil/lymphocyte ratio (NLR), alpha fetoprotein (AFP), cancer antigen 125 (CA 125), cancer antigen 19-9 (CA 19-9), cancer antigen 15-3 (CA 15-3), carsino embryonic antigen (CEA) levels...
July 2016: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/28471052/supplementation-with-triptolide-increases-resistance-to-environmental-stressors-and-lifespan-in-c-elegans
#13
Sung-Jin Kim, Sun-Mi Beak, Sang-Kyu Park
Triptolide is a major active compound found in Tripterygium wilfordii., also known as Thunder God Vine. Triptolide has been shown to have anti-inflammatory and anticancer activities. In this study, we examined the effect of dietary supplementation with triptolide on response to environmental stressors and lifespan in vivo using Caenorhabditis elegans as a model system. Treatment with 50 mg/L of triptolide in the growth media increased resistance to oxidative stress and reduced the generation of intracellular reactive oxygen species...
May 4, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28467097/exclusive-breastfeeding-is-more-common-among-hiv-infected-than-hiv-uninfected-kenyan-mothers-at-6-weeks-and-6-months-postpartum
#14
Shadrack Oiye, Walter Mwanda, Mary Mugambi, Suzanne Filteau, Victor Owino
OBJECTIVE: To compare breastfeeding practices determined by mothers' own recall versus a stable isotope technique (deuterium oxide dilution) among human immunodeficiency virus (HIV)-infected and HIV-uninfected mothers at 6 weeks and 6 months postpartum. METHODS: Exclusive breastfeeding (EBF) rates were assessed cross-sectionally at 6 weeks and 6 months postpartum among 75 HIV-positive and 68 HIV-negative women attending postnatal care. EBF was derived from maternal 24-hour recall of foods that were fed to the infant and by objective measurement of nonhuman milk-water intake using deuterium oxide (DO) dilution technique...
May 3, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28459228/risk-factors-for-surgical-site-infection-after-hysterectomy
#15
Hale Göksever Çelik, Engin Çelik, Gökçe Turan, Kerem Doğa Seçkin, Ali Gedikbaşı
INTRODUCTION: The aim of the study was to define the clinical and laboratory characteristics of patients who had surgical site infection (SSI) after hysterectomy. METHODOLOGY: This study was a retrospective cohort study. The patient data of 840 subjects who had undergone any type of hysterectomy and reported SSI after surgery were obtained from the archives of a tertiary referral center. The different types of hysterectomy procedures performed on these patients included total abdominal hysterectomy (TAH), laparoscopic hysterectomy (LH), and vaginal hysterectomy (VH)...
April 30, 2017: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/28455888/helicobacter-infection-significantly-alters-pregnancy-success-in-laboratory-mice
#16
Tara C Bracken, Caitlin A Cooper, Zil Ali, Ha Truong, Julie M Moore
Helicobacter spp. are gram-negative, helically shaped bacteria that cause gastric and enterohepatic infections in mammalianspecies. Although Helicobacter infection frequently is implicated to interfere with reproductive success, few experimentaldata support these claims. We therefore retrospectively investigated the effect of Helicobacter infection on murine pregnancy outcome after the identification of endemic Helicobacter infection in an animal research facility. Multiplex conventional PCR analysis was used to characterize Helicobacter infection status in one inbred and 2 transgenic strains of mice in 2 self-contained rooms assigned to the same investigator...
April 28, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28455085/randomized-controlled-trial-of-intravenous-acetaminophen-for-post-cesarean-delivery-pain-control
#17
Brie Altenau, Catrina C Crisp, C Ganga Devaiah, Donna S Lambers
BACKGROUND: Cesarean delivery is a common surgery in the United States with 1.3 million performed during 2009.(1) Obstetricians must balance the growing concern with opioid abuse, dependence and side effects with optimal post-operative pain control. IV acetaminophen may represent an additional method to decrease the reliance on opioid medications and improve post-operative pain following cesarean section. OBJECTIVE: To determine if administration of IV acetaminophen following routine scheduled cesarean delivery would decrease the need for narcotic medications to control post-operative pain...
April 25, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28449651/impacts-of-counseling-on-knowledge-attitude-and-practice-of-medication-use-during-pregnancy
#18
Ramesh Devkota, G M Khan, Kadir Alam, Binaya Sapkota, Deepa Devkota
BACKGROUND: Counseling has a significant role in improving knowledge, attitude and practice outcomes of pregnant women towards medication use. Proper counseling thus could be beneficial to prevent any medication related misadventure during pregnancy. The present study was aimed to assess the knowledge, attitude and practice (KAP) of pregnant women towards their medications, to provide counseling regarding their understanding of medication use during pregnancy and evaluate the impacts of such counseling...
April 27, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28448320/difficult-airway-management-resulting-from-local-anesthetic-allergy-during-emergent-cesarean-delivery-a-case-report
#19
Courtney L Maxey-Jones, Alec Palmerton, Jocelyn R Farmer, Brian T Bateman
Difficult airway management in the gravid patient is a well-described phenomenon. We present a case of emergent cesarean delivery complicated by a "cannot intubate, cannot ventilate" scenario that was later determined to be secondary to an allergic, IgE-mediated reaction to epidurally administered local anesthetic.
April 26, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28445440/micronutrient-status-among-pregnant-women-in-zinder-niger-and-risk-factors-associated-with-deficiency
#20
K Ryan Wessells, Césaire T Ouédraogo, Rebecca R Young, M Thierno Faye, Alex Brito, Sonja Y Hess
Anemia and micronutrient (MN) deficiencies in pregnant women are associated with adverse pregnancy outcomes. In Niger, 58.6% of pregnant women are anemic; however, MN statuses are unknown. The study objectives were to estimate the prevalence of MN deficiencies among pregnant women in Zinder, Niger and explore associated risk factors. Pregnant women living in randomly selected rural villages (n = 88) were included. Capillary and venous blood samples (n = 770) were analyzed for hemoglobin (Hb) and plasma ferritin, soluble transferrin receptor (sTfR), zinc (pZn), retinol binding protein (RBP), folate and vitamin B12...
April 26, 2017: Nutrients
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