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https://www.readbyqxmd.com/read/29330015/mother-to-child-transmission-of-extended-spectrum-beta-lactamase-producing-enterobacteriaceae
#1
Dana Danino, Rimma Melamed, Batya Sterer, Nurith Porat, Guy Hazan, Alex Gushanski, Eilon Shany, David Greenberg, Avraham Borer
BACKGROUND: Preterm infants are at high risk for extended spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) sepsis and neonatal intensive care unit (NICU) outbreaks. Maternal colonization with ESBL-E may be precursory to maternal-neonatal transmission. However, there is no consensus regarding surveillance of pregnant women for ESBL-E colonization. AIM: To identify pairs of mothers and offspring harbouring same-strain ESBL-E colonization and to determine whether maternal transmission may play a role in increasing ESBL-E carriage in preterm infants...
January 9, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29324745/proof-of-concept-study-of-an-at-home-engaging-digital-intervention-for-pediatric-adhd
#2
Naomi O Davis, Jeffrey Bower, Scott H Kollins
OBJECTIVE: Pharmacological and behavioral therapies have limited impact on the distinct neurocognitive impairments associated with ADHD, and existing cognitive training programs have shown limited efficacy. This proof-of-concept study assessed treatment acceptability and explored outcomes for a novel digital treatment targeting cognitive processes implicated in ADHD. METHOD: Participants included 40 children with ADHD and 40 children without ADHD. Following psychiatric screening, ADHD ratings, and baseline neuropsychological measures, participants completed 28-days of at-home treatment...
2018: PloS One
https://www.readbyqxmd.com/read/29298252/adolescent-attitudes-toward-sexually-transmitted-infection-screening-in-the-emergency-department
#3
Addison S Gearhart, Gia M Badolato, Monika K Goyal
OBJECTIVES: Adolescents who seek care in emergency departments (EDs) are often at high risk for sexually transmitted infections (STIs). The objective of this study was to assess adolescent attitudes toward ED-based STI screening. METHODS: We conducted a secondary analysis of a cross-sectional study that evaluated STI screening acceptability and prevalence when STI testing was universally offered to asymptomatic adolescents presenting to the ED for care. Adolescents 14 to 21 years old completed a computerized survey and answered questions regarding attitudes toward ED-based STI screening and sexual behavior...
January 2, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29296931/bone-disease-in-monoclonal-gammopathy-of-undetermined-significance-results-from-a-screened-population-based-study
#4
Sigrun Thorsteinsdottir, Sigrun H Lund, Ebba K Lindqvist, Marianna Thordardottir, Gunnar Sigurdsson, Rene Costello, Debra Burton, Hlif Steingrimsdottir, Vilmundur Gudnason, Gudny Eiriksdottir, Kristin Siggeirsdottir, Tamara B Harris, Ola Landgren, Sigurdur Y Kristinsson
Previous studies have shown that individuals with monoclonal gammopathy of undetermined significance (MGUS) have an increased risk of fractures, although the underlying mechanisms remain unknown. Our aim was to analyze bone mineral density (BMD), bone volume, and risk of fractures among individuals with MGUS. We performed a screening using the Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study cohort, consisting of 5764 elderly individuals, identifying 300 individuals with MGUS, and 275 with light-chain MGUS...
December 26, 2017: Blood Advances
https://www.readbyqxmd.com/read/29290259/radiomics-and-radiogenomics-in-lung-cancer-a-review-for-the-clinician
#5
REVIEW
Rajat Thawani, Michael McLane, Niha Beig, Soumya Ghose, Prateek Prasanna, Vamsidhar Velcheti, Anant Madabhushi
Lung cancer is responsible for a large proportion of cancer-related deaths across the globe, with delayed detection being perhaps the most significant factor for its high mortality rate. Though the National Lung Screening Trial argues for screening of certain at-risk populations, the practical implementation of these screening efforts has not yet been successful and remains in high demand. Radiomics refers to the computerized extraction of data from radiologic images, and provides unique potential for making lung cancer screening more rapid and accurate using machine learning algorithms...
January 2018: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29288881/a-novel-screening-method-to-identify-late-stage-dementia-patients-for-palliative-care-research-and-practice
#6
Natalie C Ernecoff, Kathryn L Wessell, Stacey Gabriel, Timothy S Carey, Laura C Hanson
CONTEXT: Investigators need novel methods for timely identification of patients with serious illness to test or implement new palliative care models. OBJECTIVE: The study aim was to develop an electronic health record (EHR) phenotype to identify patients with late-stage dementia for a clinical trial of palliative care consultation. METHODS: We developed a computerized method to identify patients with dementia on hospital admission. Within a data warehouse derived from the hospital's EHR, we used search terms of age, admission date, and ICD-9 and ICD-10 diagnosis codes to create a EHR dementia phenotype, followed by brief medical record review to confirm late-stage dementia...
December 27, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29287215/impact-of-vagus-nerve-stimulation-on-sleep-related-breathing-disorders-in-adults-with-epilepsy
#7
Aude Salvadé, Philippe Ryvlin, Andrea O Rossetti
BACKGROUND: Vagus nerve stimulation (VNS) can induce a sleep apnea syndrome (SAS), which in turn can worsen seizure control and represents a cardiovascular risk factor. Epidemiology of VNS-induced SAS has received little attention to date. The purpose of this study was to estimate the VNS-induced SAS prevalence and to explore clinical variables potentially correlating with its development. METHODS: We analyzed the computerized medical records of 18 consecutive adults treated for refractory epilepsy with VNS, implanted between May 2008 and October 2015...
December 26, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29286595/galantamine-and-computerized-cognitive-behavioral-therapy-for-cocaine-dependence-a-randomized-clinical-trial
#8
Kathleen M Carroll, Charla Nich, Elise E DeVito, Julia M Shi, Mehmet Sofuoglu
OBJECTIVE: To examine whether galantamine, a cognitive-enhancing medication that is both acetylcholinesterase inhibitor and agonist at nicotinic acetylcholine receptors, is effective at improving cocaine use outcomes and cognitive functioning, alone and in combination with computerized cognitive behavioral therapy (CBT). METHOD: A 12-week, randomized 2 × 2, factorial trial was conducted to evaluate galantamine versus placebo (double-blind) and computerized CBT plus standard methadone treatment versus standard methadone treatment alone in a community-based methadone maintenance program (September 2009-April 2015)...
December 26, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29284986/management-of-tooth-surface-loss-of-varying-etiology-with-full-mouth-all-ceramic-computer-aided-design-computer-aided-manufacture-restorations
#9
Nirmal Famila Bettie, Saravanan Kandasamy, Venkat Prasad
The anatomical form of a tooth can undergo changes leading to loss of tooth form. The loss of tooth surface can be due to varying etiology. Dental caries, attrition, abrasion, erosion, involving any surface of the tooth can lead to loss of tooth structure. The rate of tooth destruction may proceed to such an extent that the esthetics, function and comfort may be lost. The role of a practioner lies in identification and screening of such case and motivate for oral rehabilitation that includes habit cessation...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284443/readiness-to-change-and-therapy-outcomes-of-an-innovative-psychotherapy-program-for-surgical-patients-results-from-a-randomized-controlled-trial
#10
Henning Krampe, Anna-Lena Salz, Léonie F Kerper, Alexander Krannich, Tatjana Schnell, Klaus-Dieter Wernecke, Claudia D Spies
BACKGROUND: Readiness to change is a pivotal construct for psychotherapy research and a major target of motivational interventions. Our primary objective was to examine whether pre-treatment readiness to change moderated therapy effects of Bridging Intervention in Anesthesiology (BRIA), an innovative psychotherapy approach for surgical patients. This stepped care program aims at motivating and supporting surgical patients with mental disorders to engage in psychosocial mental health care...
December 29, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29282534/computerized-cognitive-training-in-prostate-cancer-patients-on-androgen-deprivation-therapy-a-pilot-study
#11
Lisa M Wu, Ali Amidi, Molly L Tanenbaum, Gary Winkel, Wayne A Gordon, Simon J Hall, Katrin Bovbjerg, Michael A Diefenbach
PURPOSE: Prostate cancer patients who have undergone androgen deprivation therapy (ADT) may experience cognitive impairment, yet there is an unmet need for nonpharmacological interventions to address cognitive impairment in this population. This study examines the feasibility, acceptability, and preliminary efficacy of a home-based computerized cognitive training (CCT) program to treat cancer-related cognitive impairment. METHODS: Sixty men who had received ≥ 3 months of ADT were screened for at least mild cognitive or neurobehavioral impairment and randomized to 8 weeks of CCT or usual care...
December 27, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29278776/the-development-and-evolution-of-a-computerized-testing-system-for-primates-cognition-welfare-and-the-rumbaughx
#12
Bonnie M Perdue, Michael J Beran, David A Washburn
Innovations in apparatus technology come about for a variety of reasons such as the need to use the same methodology with various species, the opportunity to present dynamic and carefully controlled stimuli, the goal of using automation to make data collection more precise or efficient, and the need to control for and/or eliminate the presence of experimenters in the testing context. At the Language Research Center (LRC) of Georgia State University, a computer-based system has been developed and used extensively with nonhuman primate species...
December 23, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/29248912/screening-for-fabry-disease-in-kidney-disease-a-cross-sectional-study-in-males-and-females
#13
Luciana Senra de Souza Sodré, Rosália Maria Nunes Henriques Huaira, Marcus Gomes Bastos, Fernando Antônio Basile Colugnati, Marcelo Paula Coutinho, Natália Maria da Silva Fernandes
BACKGROUND/AIMS: Evaluate the prevalence of Fabry disease in men and women with kidney disease; and observe the presence and importance of the main signs and symptoms in patients with kidney disease. METHODS: A cross-sectional analysis of secondary data from a multicenter project of Clinical and Epidemiological Analysis of Fabry Disease in 854 Dialysis Centers. A total of 36,442 patients underwent the questionnaire and algorithm; of them, 28,284 were discarded for not presenting signs and symptoms of Fabry disease, while the other 8,087 submitted to blood collection and analysis...
December 14, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29248158/the-role-of-left-insula-in-executive-set-switching-lesion-evidence-from-an-acute-stroke-cohort
#14
Andreja Varjačić, Dante Mantini, Jacob Levenstein, Elitsa D Slavkova, Nele Demeyere, Céline R Gillebert
Impairments in executive functions are common in stroke survivors, both in the acute and in the chronic phase. However, little is known about the underlying lesion neuroanatomy of these deficits. This study aimed to elucidate the pattern of brain damage underlying executive dysfunction in a large and acute stroke cohort. Executive set-switching deficits were evaluated by a shape-based analogue of the Trail Making Test (from the Oxford Cognitive Screen) in a consecutive sample of 144 stroke patients (age: 70 ± 15 years, examination: 5 ± 4 days post-stroke; brain imaging: 1...
November 22, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29242045/defining-the-applicant-pool-for-postgraduate-year-2-categorical-general-surgery-positions
#15
Weston Stover, Sujata Gill, Kim Schenarts, A Alfred Chahine
OBJECTIVE: In the spring of 2010, a categorical general surgery postgraduate year (PGY)-2 position became available at our academic medical center secondary to attrition of a PGY-1 resident. We sought to study the unique characteristics of applicants to that position and to describe the selection process with hopes to stimulate additional studies about the unique challenges of recruiting applicants into advanced standing positions. DESIGN: Applications were received via e-mail and reviewed to characterize the applicant pool...
December 11, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/29239998/seasonal-changes-in-functional-fitness-and-neurocognitive-assessments-in-youth-ice-hockey-players
#16
Michelle Avery, Nick Wattie, Michael Holmes, Shilpa Dogra
Deficits in balance and strength combined with differing rates of sensory and motor neural development may increase risk of sports related injury in youth. This study evaluated changes in functional fitness and concussion status over the course of a competitive season in youth ice-hockey players, and examined the relationship between these variables and injury occurrence. Thirty-six participants (8.9 ± 1.1 years) completed pre and post-season assessments including anthropometric measurements, the Functional Movement Screen (FMS), Lower Quarter Y-Balance Test (YBT-LQ), and a computerized neurocognitive assessment (ImPACT)...
December 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29236188/contributors-to-nonsuicidal-self-injury-in-incarcerated-youth
#17
Larkin Street McReynolds, Gail Wasserman, Elise Ozbardakci
BACKGROUND: Despite elevations in risks associated with self-injurious behavior among community adolescents, the degree to which these features are associated with self-injury among incarcerated youth has rarely been examined. Although the DSM-5 recently proposed a distinct category of nonsuicidal self-injury (NSSI), most studies of youths in forensic settings have not distinguished between subtypes of self-harming individuals. METHODS: Demographic, offense, and disorder contributors to NSSI in incarcerated youths of both genders (N = 358) were examined via a computerized self-report instrument (VISA), largely consistent with DSM-5...
December 13, 2017: Health & Justice
https://www.readbyqxmd.com/read/29231513/-application-of-data-mining-on-the-relationship-between-deqi-and-effect
#18
Qiuyin Pan, Liangxiao Ma, Yang Yang, Jiang Zhu
OBJECTIVE: To analyze the relationship between deqi and effect by data mining technique with retrieving clinical literature about acupuncture deqi since the founding of the country. METHODS: The modern computerization and data mining technologies were adopted to set up clinical literature about acupuncture deqi database. The relevant clinical literature was collected, screened, extracted, and statistical and correlation analyses were used so as to explore the relationship between deqi and effect...
June 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29229000/changes-in-specific-substance-involvement-scores-among-sbirt-recipients-in-an-hiv-primary-care-setting
#19
Carol Dawson-Rose, Jessica E Draughon, Yvette Cuca, Roland Zepf, Emily Huang, Bruce A Cooper, Paula J Lum
BACKGROUND: Substance use is common among people living with HIV (PLHIV) and is associated with worse outcomes along the HIV care continuum. One potentially effective clinic-based approach to addressing unhealthy substance use is screening, brief intervention, and referral to treatment (SBIRT). METHODS: We conducted a two-arm randomized trial to examine the effects of a self-administered, computerized SBIRT intervention compared to a clinician-administered SBIRT intervention in an HIV primary clinic...
December 12, 2017: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/29227903/sensory-processing-difficulties-in-school-age-children-born-very-preterm-an-exploratory-study
#20
Tinka Bröring, Marsh Königs, Kim J Oostrom, Harrie N Lafeber, Anniek Brugman, Jaap Oosterlaan
BACKGROUND: Very preterm birth has a detrimental impact on the developing brain, including widespread white matter brain abnormalities that threaten efficient sensory processing. Yet, sensory processing difficulties in very preterm children are scarcely studied, especially at school age. AIMS: To investigate somatosensory registration, multisensory integration and sensory modulation. PARTICIPANTS: 57 very preterm school-age children (mean age=9...
December 8, 2017: Early Human Development
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