keyword
https://read.qxmd.com/read/38172816/predicting-stone-composition-via-machine-learning-models-trained-on-intra-operative-endoscopic-digital-images
#21
JOURNAL ARTICLE
Guanhua Zhu, Chengbai Li, Yinsheng Guo, Lu Sun, Tao Jin, Ziyue Wang, Shiqing Li, Feng Zhou
OBJECTIVES: The aim of this study was to use deep learning (DL) of intraoperative images of urinary stones to predict the composition of urinary stones. In this way, the laser frequency and intensity can be adjusted in real time to reduce operation time and surgical trauma. MATERIALS AND METHODS: A total of 490 patients who underwent holmium laser surgery during the two-year period from March 2021 to March 2023 and had stone analysis results were collected by the stone laboratory...
January 3, 2024: BMC Urology
https://read.qxmd.com/read/38154005/a-cost-savings-analysis-of-topical-estrogen-therapy-in-uti-prevention-among-postmenopausal-women
#22
JOURNAL ARTICLE
Charlotte Goldman Houston, William S Azar, Sean Shenghsiu Huang, Rachel Rubin, C Scott Dorris, Rachael Sussman
INTRODUCTION: Urinary tract infections (UTI) are some of the most common infections in geriatric patients, with many women experiencing recurrent infections after menopause. In the United States annual UTI related costs are 2 billion dollars, with recurrent infections creating a significant economic burden. Given the data published on topical estrogen in reducing the number of infections for postmenopausal women with recurrent UTI, we sought to evaluate how this would translate to cost saving...
December 28, 2023: Urology Practice
https://read.qxmd.com/read/38150152/lack-of-microbiological-awareness-on-the-ward-as-a-key-factor-for-inappropriate-use-of-anti-infectives-results-of-a-point-prevalence-study-and-user-satisfaction-survey-in-a-large-university-hospital-in-austria
#23
JOURNAL ARTICLE
Jan Marco Kern, Karoline Berger, Arno Michael Lechner, Ulrike Porsche, Markus Wallner, Eva Maria Past
PURPOSE: Although diagnostic stewardship issues in clinical microbiology harbor an optimization potential for anti-infective consumption, they are only marginally addressed in antimicrobial stewardship (AMS) programs. As part of an AMS point prevalence (PPS) survey we therefore aimed to gain a more dynamic view on the microbiological awareness within therapeutic regimens. By examining whether initial microbiological sampling was performed and in which way microbiological results were incorporated into further treatment considerations we sought to find out to what extent these points determine the appropriateness of treatment regimens...
December 27, 2023: Infection
https://read.qxmd.com/read/38104629/seroprevalence-to-schistosoma-soluble-egg-antigen-among-nomadic-pastoralists-residing-in-northern-senegal
#24
JOURNAL ARTICLE
Mame Cheikh Seck, Aida Sadikh Badiane, Julie Thwing, Mouhamadou Ndiaye, Khadim Diongue, Ibrahima Mbaye Ndiaye, Mamadou Alpha Diallo, Mohamed Sy, Jules François Gomis, Tolla Ndiaye, Aminata Gaye, Yeuk-Mui Lee, W Evan Secor, Daouda Ndiaye, Eric Rogier
Urinary and intestinal schistosomiasis are endemic in Senegal, with prevalence heterogeneous throughout the country. Because of their way of life, nomadic pastoralists are not typically included in epidemiological surveys, and data on the prevalence of schistosomiasis in Senegalese nomadic populations are largely non-existent. The purpose of this study was to determine the seroprevalence of schistosomiasis in Senegalese nomadic pastoralists. A modified snowball sampling survey was conducted among 1,467 nomadic pastoralists aged 6 mo and older in 5 districts in northern Senegal...
November 1, 2023: Journal of Parasitology
https://read.qxmd.com/read/38066418/investigating-the-impact-of-an-online-hydration-intervention-in-care-homes-using-the-com-b-model-a-mixed-methods-study
#25
JOURNAL ARTICLE
Danielle McMichael, Patricia Gillen, Caroline McGeary, Muhammad Sartaj, Lynsey Patterson
BACKGROUND: Antimicrobial resistance is a serious threat to public health. To reduce antimicrobial resistance, interventions to reduce gram-negative infections, specifically urinary tract infections, are vital. Early evidence suggests increased fluid intake is linked with a reduction in UTIs and subsequently has potential to reduce antibiotic usage. Care homes have a high prevalence of UTIs and provide an opportunity in a closed setting to deliver an intervention focused on increasing fluid intake, where it is supported and monitored by health care workers...
December 8, 2023: BMC Geriatrics
https://read.qxmd.com/read/38060572/resveratrol-encapsulated-glutathione-modified-robust-mesoporous-silica-nanoparticles-as-an-antibacterial-and-antibiofilm-coating-agent-for-medical-devices
#26
JOURNAL ARTICLE
Mohini Verma, Anjali Nisha, Manik Bathla, Amitabha Acharya
The emergence of various lethal bacterial infections and their adherence to medical devices are major public health concerns. The increased bacterial exposure and titer are accompanied by the inappropriate use of antibiotics that sometimes lead to antibiotic resistance, and therefore, a drug-free antibacterial approach is required. Several nanoparticles (NPs) have been developed as antibacterial and antibiofilm coating agents, which can overcome different drug resistance mechanisms by inhibiting the important processes related to bacterial virulence potential...
December 7, 2023: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38045654/influencing-factors-of-massive-hemorrhage-and-high-grade-renal-vascular-injury-after-pcnl-a-retrospective-comparative-study
#27
JOURNAL ARTICLE
Qiushi He, Ziyan Song, Xinrui Wang, Bingbing Hou, Zongyao Hao
PURPOSE: Severe hemorrhage after percutaneous nephrolithotomy (PCNL) is a rare but alerting event. In this study, we report the factors affecting massive hemorrhage after PCNL, various levels of vascular damage during renal angiography, and the therapeutic effect of superselective renal artery embolization (SRAE). Patients and Methods . A retrospective analysis was performed on the data of 69 patients with postoperative PCNL hemorrhage who underwent SRAE from January 2010 to March 2021...
2023: International Journal of Clinical Practice
https://read.qxmd.com/read/38029257/alterations-in-urinary-microbiota-composition-in-urolithiasis-patients-insights-from-16s-rrna-gene-sequencing
#28
JOURNAL ARTICLE
Haoran Liu, Qingqing Hu, Qunsheng Yan, Zongyao Hao, Chaozhao Liang
OBJECTIVES: To investigate the urinary microbiota composition in urolithiasis patients compared to healthy controls and to identify potential microbial markers and their association with clinical parameters. METHODS: A total of 66 samples, comprising 45 from urolithiasis patients and 21 from healthy controls, were analyzed. 16S rRNA gene sequencing was employed to determine the microbiota composition. Various statistical and bioinformatics tools, including ANOVA, PCoA, and LEfSe, were utilized to analyze the sequencing data and identify significant differences in microbial abundance...
2023: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/37953342/contribution-of-medico-administrative-databases-to-health-vigilance-example-of-post-oocyte-retrieval-infections
#29
JOURNAL ARTICLE
G Lemardeley, G Porcu-Buisson, O Pirrello, J Gane, S Dieterlé, C Astrugue, T Charbonnier, S Lucas-Samuel, C Couchoud
STUDY QUESTION: Can we monitor post-oocyte retrieval infections in the French national health data system to complement the French ART vigilance system? SUMMARY ANSWER: Medico-administrative databases provide a more comprehensive view of post-oocyte retrieval infections and can be used to detect abnormal increases in frequency and outlier ART centers as a complementary tool to the ART vigilance system. WHAT IS KNOWN ALREADY: The various studies of ART complications are reassuring, showing relatively low overall complication rates...
November 11, 2023: Human Reproduction
https://read.qxmd.com/read/37933042/clinical-application-of-a-novel-stent-assisted-in-situ-intestinal-bypass-in-preventing-postoperative-anastomotic-leakage-for-low-mid-rectal-cancer-a-retrospective-study
#30
JOURNAL ARTICLE
Xiong Zhou, Lian Bai, Qi-Gang Li, Jian Xie, Chang-An Liu, Ze-Lin Wen
This study aimed to investigate the safety and feasibility of a novel stent-assisted in situ intestinal bypass for low-mid rectal cancer patients. Patients who were diagnosed with rectal cancer and received laparoscopic low anterior rectal resection plus a novel stent-assisted in situ intestinal bypass were respectively included from March 2022 to June 2022. Biofragmentable intestinal stent with a protective sleeve was placed in the proximal colon before anastomosis, and feces could be discharged through the protective sleeve without touching the anastomosis, which achieved an in situ bypass of feces...
November 3, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37906221/human-papillomavirus-hpv-infections-among-participants-undergoing-chlamydia-trachomatis-testing-in-reunion-island-run-surv-hpv-study-protocol-for-a-prevalence-study
#31
JOURNAL ARTICLE
Maxence Gandelin, Phuong Lien Tran, Emmanuel Chirpaz, Marie-Christine Jaffar-Bandjee, Nicolas Traversier, Dorothy Machalek, Antoine Bertolotti
BACKGROUND: Infection by human papillomavirus (HPV) induces various cancers, mainly cervical cancer but also anal and pharyngeal cancers. Reunion Island is a French department in the Indian Ocean. Due to the history of its settlement, the island's population has a wide variety of origins, and the population's sociodemographic characteristics differ from those of the French mainland. These characteristics make the island's population an original French population in its own right, particularly in terms of health...
October 31, 2023: JMIR Research Protocols
https://read.qxmd.com/read/37902379/control-of-glna-glutamine-synthetase-expression-by-urea-in-non-pathogenic-and-uropathogenic-escherichia-coli
#32
JOURNAL ARTICLE
Karthik Urs, Philippe E Zimmern, Larry Reitzer
Previous transcriptomic studies have shown that glnA , which codes for glutamine synthetase (GS), is induced during growth of uropathogenic E. coli in urine. GS is at the intersection of carbon and nitrogen metabolism and is, not surprisingly, highly regulated. The glnALG operon specifies GS and two regulators of the nitrogen-regulated (Ntr) response, which scavenges nitrogenous compounds during nitrogen limitation. Transcription of glnA initiates from the cAMP receptor protein (Crp)-dependent glnAp1 and the GlnG-dependent glnAp2 promoters which respond to carbon and nitrogen limitation, respectively...
October 30, 2023: Journal of Bacteriology
https://read.qxmd.com/read/37900519/specialty-impact-on-patient-outcomes-paving-a-way-for-an-integrated-approach-to-spinal-disorders
#33
REVIEW
Venkataramana Kuruba, Anjani Mahesh Kumar Cherukuri, Subiksha Arul, Abdulaziz Alzarooni, Sheryl Biju, Taimur Hassan, Riya Gupta, Saya Alasaadi, Jarin Tasnim Sikto, Arnav C Muppuri, Humza F Siddiqui
Spinal surgical procedures are steadily increasing globally due to broad indications of certain techniques encompassing a wide spectrum of conditions, including degenerative spine disorders, congenital anomalies, spinal metastases, and traumatic spinal fractures. The two specialties, neurosurgery (NS) and orthopedic surgery (OS), both possess the clinical adeptness to perform these procedures. With the advancing focus on comparative effectiveness research, it is vital to compare patient outcomes in spine surgeries performed by orthopedic surgeons and neurosurgeons, given their distinct approaches and training backgrounds to guide hospital programs and physicians to consider surgeon specialty when making informed decisions...
September 2023: Curēus
https://read.qxmd.com/read/37898607/hierarchical-ai-enables-global-interpretation-of-culture-plates-in-the-era-of-digital-microbiology
#34
JOURNAL ARTICLE
Alberto Signoroni, Alessandro Ferrari, Stefano Lombardi, Mattia Savardi, Stefania Fontana, Karissa Culbreath
Full Laboratory Automation is revolutionizing work habits in an increasing number of clinical microbiology facilities worldwide, generating huge streams of digital images for interpretation. Contextually, deep learning architectures are leading to paradigm shifts in the way computers can assist with difficult visual interpretation tasks in several domains. At the crossroads of these epochal trends, we present a system able to tackle a core task in clinical microbiology, namely the global interpretation of diagnostic bacterial culture plates, including presumptive pathogen identification...
October 28, 2023: Nature Communications
https://read.qxmd.com/read/37886025/dual-challenge-of-a-cecoureterocele-with-calculus-a-rare-case-report
#35
Yuvaraj Muralidharan, Iffath Misbah, Afwaan Faizal, Paarthipan Natarajan
Ureteroceles are the most prevalent urinary tract malformations in humans. Only 5% of ureteroceles are predicted to prolapse and it usually occurs in childhood. We outline the clinical history, radiological results, and a potential course of treatment for this challenging condition. A 32-year-old female checked herself into our institution with complaints of burning urination and 20 years of complaints of urethral ballooning when urinating. Initial sonographic evaluation revealed that at the left vesicoureteric junction, a cystic lesion extends into the bladder, with a hyperechoic focus causing posterior acoustic shadowing...
January 2024: Radiology Case Reports
https://read.qxmd.com/read/37872476/repurposing-carvacrol-cinnamaldehyde-and-eugenol-as-potential-anti-quorum-sensing-agents-against-uropathogenic-escherichia-coli-isolates-in-alexandria-egypt
#36
JOURNAL ARTICLE
Hadeer A Morgaan, Hoda M G Omar, Azza S Zakaria, Nelly M Mohamed
BACKGROUND: Urinary tract infections represent one of the most frequent hospital and community-acquired infections with uropathogenic Escherichia coli (UPEC) being the main causative agent. The global increase in the emergence of multidrug-resistant (MDR) UPEC necessitates exploring novel approaches. Repurposing natural products as anti-quorum sensing (QS) agents to impede bacterial virulence is gaining momentum nowadays. Hence, this study investigates the anti-QS potentials of carvacrol, cinnamaldehyde, and eugenol against E...
October 23, 2023: BMC Microbiology
https://read.qxmd.com/read/37841934/current-state-of-research-on-the-clinical-benefits-of-herbal-medicines-for-non-life-threatening-ailments
#37
Sandra Salm, Jochen Rutz, Marjan van den Akker, Roman A Blaheta, Beatrice E Bachmeier
Herbal medicines are becoming increasingly popular among patients because they are well tolerated and do not exert severe side effects. Nevertheless, they receive little consideration in therapeutic settings. The present article reviews the current state of research on the clinical benefits of herbal medicines on five indication groups, psychosomatic disorders, gynecological complaints, gastrointestinal disorders, urinary and upper respiratory tract infections. The study search was based on the database PubMed and concentrated on herbal medicines legally approved in Europe...
2023: Frontiers in Pharmacology
https://read.qxmd.com/read/37841913/impact-of-selective-reporting-of-antimicrobial-susceptibility-testing-report-on-clinicians-prescribing-behavior-of-antibiotics
#38
JOURNAL ARTICLE
Ying Wang, Xinping Zhang, Qian Zhou, Xiaojun Xu
Background: Selective reporting has important value in antibiotic management. The purpose of this study was to explore the impact of AST selective reporting on prescribing behavior, so as to provide evidence for the implementation and improvement of selective reporting policies in microbiology laboratories at home and abroad. Methods: A cross-sectional study was conducted in a teaching tertiary hospital in China in July 2021. We designed selective reports and routine reports for urinary tract infections caused by Escherichia coli and lower respiratory tract infections caused by Pseudomonas aeruginosa ...
2023: Frontiers in Pharmacology
https://read.qxmd.com/read/37803376/nursing-sensitive-quality-indicators-for-quality-improvement-in-norwegian-nursing-homes-a-modified-delphi-study
#39
JOURNAL ARTICLE
Kjerstin Tevik, Anne-Sofie Helvik, Geir-Tore Stensvik, Marion S Nordberg, Sigrid Nakrem
BACKGROUND: Use of nursing-sensitive quality indicators (QIs) is one way to monitor the quality of care in nursing homes (NHs). The aim of this study was to develop a consensus list of nursing-sensitive QIs for Norwegian NHs. METHODS: A narrative literature review followed by a non-in-person, two-round, six-step modified Delphi survey was conducted. A five-member project group was established to draw up a list of nursing-sensitive QIs from a preliminary list of 24 QIs selected from Minimum Data Set (2...
October 6, 2023: BMC Health Services Research
https://read.qxmd.com/read/37750974/the-effect-of-smoking-on-30-day-complications-following-primary-repair-of-achilles-tendon-ruptures
#40
JOURNAL ARTICLE
Anna M Ifarraguerri, Theodore Quan, Benjamin Farley, Emile-Victor Kuyl, John Koch, Philip M Parel, Alisa Malyavko, Sean Tabaie
PURPOSE: There exists a gap in the knowledge of the impact of smoking on Achilles tendon rupture repair. This study evaluates perioperative and postoperative complications associated with smoking to allow for a more informed evaluation and discussion with the patients when considering the surgical management of Achilles tendon repair in this patient population. METHODS: The National Surgical Quality Improvement Program database was queried for patients undergoing Achilles tendon rupture repair from 2006 to 2019...
September 26, 2023: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
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