Read by QxMD icon Read

Burn fat

Nicole Niehoff, Alexandra J White, Lauren E McCullough, Susan E Steck, Jan Beyea, Irina Mordukhovich, Jing Shen, Alfred I Neugut, Kathleen Conway, Regina M Santella, Marilie D Gammon
BACKGROUND: Polycyclic aromatic hydrocarbons (PAHs) have been linked to breast cancer in many, but not all, previous studies. PAHs are lipophilic and stored in fat tissue, which we hypothesized may result in constant low-dose exposure to these carcinogens. No previous studies have evaluated whether obesity modifies associations between multiple measures of PAHs and breast cancer incidence. METHODS: This population-based study included 1,006 postmenopausal women with first primary in situ or invasive breast cancer and 990 age-frequency matched controls...
October 11, 2016: Environmental Research
M E H Jaspers, K M Brouwer, A J M van Trier, M L Groot, E Middelkoop, P P M van Zuijlen
BACKGROUND: Nowadays, patients normally survive severe traumas such as burn injuries and necrotizing fasciitis. Large skin defects can be closed but the scars remain. Scars may become adherent to underlying structures when the subcutical fat layer is damaged. Autologous fat grafting (AFG) provides the possibility to reconstruct a functional sliding layer underneath the scar. AFG is becoming increasingly popular for scar treatment although large studies using validated evaluation tools are lacking...
September 14, 2016: Plastic and Reconstructive Surgery
Saverio Cinti
In all mammals, adipocytes are cells with abundant cytoplasmic lipids forming the parenchyma of the adipose organ. White adipocytes store highly energetic molecules to release them, in the form of free fatty acids to survive between meals. Brown adipocytes trough their unique mitochondrial UCP1 protein burn glucose and lipids to perform thermogenesis in order to survive in cold environments. A third type of adipocytes appears in the subcutaneous depot of the adipose organ of female mice during pregnancy and lactation: the pink adipocytes...
September 10, 2016: Biochimie
Anders H Carlsson, Lloyd F Rose, John L Fletcher, Jesse C Wu, Kai P Leung, Rodney K Chan
Current standard of care for full-thickness burn is excision followed by autologous split-thickness skin graft placement. Skin grafts are also frequently used to cover surgical wounds not amenable to linear closure. While all grafts have potential to contract, clinical observation suggests that antecedent thermal injury worsens contraction and impairs functional and aesthetic outcomes. This study evaluates the impact of antecedent full-thickness burn on split-thickness skin graft scar outcomes and the potential mediating factors...
September 3, 2016: Burns: Journal of the International Society for Burn Injuries
Melanie S Adams, Robert B Adams, Carol A Wessman, Barbara Demmig-Adams
We connect modern, intensive agriculture's role in environmental degradation to its role in producing nutritionally unbalanced foods, and delineate specific approaches to reduce agriculture's environmental impact, while producing healthful foods. We call attention to recently discovered genetic programs used by all living organisms to respond to their environment, and present a model of how these programs change body composition and function (of humans and their crop plants and livestock alike) in response to environmental cues...
2016: Frontiers in Nutrition
Ibrahim Khansa, Bridget Harrison, Jeffrey E Janis
BACKGROUND: Scars represent the visible sequelae of trauma, injury, burn, or surgery. They may induce distress in the patient because of their aesthetically unpleasant appearance, especially if they are excessively raised, depressed, wide, or erythematous. They may also cause the patient symptoms of pain, tightness, and pruritus. Numerous products are marketed for scar prevention or improvement, but their efficacy is unclear. METHODS: A literature review of high-level studies analyzing methods to prevent or improve hypertrophic scars, keloids, and striae distensae was performed...
September 2016: Plastic and Reconstructive Surgery
Weiwei Fan, Ronald Evans
No abstract text is available yet for this article.
August 19, 2016: Science
Luca Maione, Andrea Vittorio Emanuele Lisa, Valeriano Vinci, Francesco Klinger, Fabio Caviggioli, Marco Ettore Attilio Klinger
No abstract text is available yet for this article.
October 2016: Annals of Plastic Surgery
Derek J Snyder, Linda M Bartoshuk
Oral sensations (i.e., taste, oral somatosensation, retronasal olfaction) are integrated into a composite sense of flavor, which guides dietary choices with long-term health impact. The nerves carrying this input are vulnerable to peripheral damage from multiple sources (e.g., otitis media, tonsillectomy, head injury), and this regional damage can boost sensations elsewhere in the mouth because of central interactions among nerve targets. Mutual inhibition governs this compensatory process, but individual differences lead to variation in whole-mouth outcomes: some individuals are unaffected, others experience severe loss, and some encounter sensory increases that may (if experienced early in life) elevate sweet-fat palatability and body mass...
June 2016: Reviews in Endocrine & Metabolic Disorders
Charles Scott Hultman
No abstract text is available yet for this article.
October 2016: Annals of Plastic Surgery
Shruti Purohit, Devashree Jahagirdar, Azad Kumar, Nilesh Kumar Sharma
Breast cancer among women is one of the most common carcinoma worldwide. In comparison to developed country, the breast cancer cases reported in India are boosted rapidly that in near future, statistically will surpass USA. At the same time, alarming statistics indicate that ratio of mortality cases over the total incidences is significantly high in comparison to developed world (Global Heath Estimates, WHO 2015). In recent times, several oncogenic signaling pathways have shown convergent effects on various types of cancer cell metabolism including breast cancer leading to tumor development...
July 27, 2016: MicroRNA
F Accatino, D Ward, K Wiegand, C De Michele
Assessing the carrying capacity is of primary importance in arid rangelands. This becomes even more important during droughts, when rangelands exhibit non-equilibrium dynamics, and the dynamics of livestock conditions and forage resource are decoupled. Carrying capacity is usually conceived as an equilibrium concept, that is, the consumer density that can co-exist in long-term equilibrium with the resource. As one of the first, here we address the concept of carrying capacity in systems, where there is no feedback between consumer and resource in a limited period of time...
July 25, 2016: Animal: An International Journal of Animal Bioscience
María Calderon-Dominguez, David Sebastián, Raquel Fucho, Minéia Weber, Joan F Mir, Ester García-Casarrubios, María Jesús Obregón, Antonio Zorzano, Ángela M Valverde, Dolors Serra, Laura Herrero
The discovery of active brown adipose tissue (BAT) in adult humans and the fact that it is reduced in obese and diabetic patients have put a spotlight on this tissue as a key player in obesity-induced metabolic disorders. BAT regulates energy expenditure through thermogenesis; therefore, harnessing its thermogenic fat-burning power is an attractive therapeutic approach. We aimed to enhance BAT thermogenesis by increasing its fatty acid oxidation (FAO) rate. Thus, we expressed carnitine palmitoyltransferase 1AM (CPT1AM), a permanently active mutant form of CPT1A (the rate-limiting enzyme in FAO), in a rat brown adipocyte (rBA) cell line through adenoviral infection...
2016: PloS One
Daniel Thomas, Ravindra Majeti
Obese leukemia patients exhibit reduced survival after chemotherapy, suggesting an important role of adipose tissue in disease progression. In this issue of Cell Stem Cell, Ye et al. (2016) reveal metabolic heterogeneity in leukemic stem cell (LSC) subpopulations and show that chemotherapy-resistant CD36+ LSCs co-opt gonadal adipose tissue to support their metabolism and survival.
July 7, 2016: Cell Stem Cell
Eun Jin Kim, Hyoung Il Kwon, Un Cheol Yeo, Joo Yeon Ko
As demand for a youthful appearance has increased, various techniques for face lifting and contouring have been used to reduce excess fat deposition and improve skin laxity. Recently, radiofrequency (RF)-assisted lipolysis and liposuction (RFAL) has been introduced for body and face contouring. This study aimed to evaluate the clinical improvement and safety of a new RFAL device for face lifting and contouring. A prospective study was conducted in 20 Korean patients who underwent an internal real-time thermosensing monopolar RFAL procedure...
September 2016: Lasers in Medical Science
Didier F Pisani, Olivier Dumortier, Guillaume E Beranger, Virginie Casamento, Rayane A Ghandour, Maude Giroud, Nadine Gautier, Thierry Balaguer, Jean-Claude Chambard, Kirsi A Virtanen, Pirjo Nuutila, Tarja Niemi, Markku Taittonen, Emmanuel Van Obberghen, Charlotte Hinault, Ez-Zoubir Amri
Human brown adipocytes are able to burn fat and glucose and are now considered as a potential strategy to treat obesity, type 2 diabetes and metabolic disorders. Besides their thermogenic function, brown adipocytes are able to secrete adipokines. One of these is visfatin, a nicotinamide phosphoribosyltransferase involved in nicotinamide dinucleotide synthesis, which is known to participate in the synthesis of insulin by pancreatic β cells. In a therapeutic context, it is of interest to establish whether a potential correlation exists between brown adipocyte activation and/or brite adipocyte recruitment, and adipokine expression...
April 2016: Adipocyte
Rebecca L Burns, Sharukh J Bhavnagri
Mesenteric panniculitis is a rare inflammatory and fibrotic process that affects the small intestine mesentery. It may occur following abdominal surgery or in association with a variety of conditions, including malignancy, infection, and certain autoimmune and inflammatory conditions. Herein, an unusual case of mesenteric panniculitis in a patient with primary Sjögren's syndrome will be presented. The patient presented with abdominal pain, weight loss, sicca symptoms, fatigue, and arthralgia. An abdominal CT revealed mesenteric fat stranding and prominent lymph nodes of the small intestine mesentery...
2016: Case Reports in Rheumatology
Ryan M Miller, Toby L Chambers, Stephen P Burns, Michael P Godard
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Kathleen F Janz, Elena M Letuchy, Trudy L Burns, Soyang Kwon, Julie M Gilmore-Eichenberger, James C Torner, Steven M Levy
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Marc G Jeschke, Abdikarim Abdullahi, Marjorie Burnett, Sarah Rehou, Mile Stanojcic
OBJECTIVE: To determine whether metformin can achieve glucose control no worse than insulin (noninferiority) without the danger of hypoglycemia (superiority). In addition, to assess whether metformin has any additional effects on lipolysis and inflammation that will enhance burn recovery (superiority). SUMMARY BACKGROUND DATA: Hyperglycemia and insulin resistance after burn injury are associated with increased morbidity and mortality. Insulin administration improves postburn infections, severity of sepsis, and morbidity, but also causes a 4-5-fold increase in hypoglycemia, which is associated with a 9-fold increase in mortality...
September 2016: Annals of Surgery
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"