Karla Helena-Bueno, Mariia Yu Rybak, Chinenye L Ekemezie, Rudi Sullivan, Charlotte R Brown, Charlotte Dingwall, Arnaud Baslé, Claudia Schneider, James P R Connolly, James N Blaza, Bálint Csörgő, Patrick J Moynihan, Matthieu G Gagnon, Chris H Hill, Sergey V Melnikov
To conserve energy during starvation and stress, many organisms use hibernation factor proteins to inhibit protein synthesis and protect their ribosomes from damage1,2 . In bacteria, two families of hibernation factors have been described, but the low conservation of these proteins and the huge diversity of species, habitats and environmental stressors have confounded their discovery3-6 . Here, by combining cryogenic electron microscopy, genetics and biochemistry, we identify Balon, a new hibernation factor in the cold-adapted bacterium Psychrobacter urativorans...
February 14, 2024: Nature