keyword
https://read.qxmd.com/read/38341907/adherence-and-impact-of-an-oral-nutritional-supplement-enriched-in-leucine-evoo-epa-and-dha-and-beta-glucans-on-the-coverage-of-energy-and-protein-requirements-in-patients-with-cancer-and-malnutrition-alisenoc-study
#21
JOURNAL ARTICLE
Samara Palma Milla, Pedro P García Luna, Alfonso Vidal Casariego, Francisco Villazón González, Tomás Martín Folgueras, Olatz Izaola Jáuregui, Silvia García Rey, Alicia Calleja Fernández, Bricia López Plaza, Tamara Casañas Quintana, Daniel A de Luis Román
OBJECTIVE: The aim of this study was to evaluate the impact of an enhanced ONS (enriched in EPA, DHA, leucine, and beta-glucans) on the dietary intake of cancer patients. METHODS: A randomized, double-blind, parallel, controlled, and multicenter clinical trial was conducted in patients with cancer and malnutrition. The trial compared prescribed dietary advice and two packs per day, for 8 weeks, of a hypercaloric (400 kcal/pack) and hyperproteic ONS (20 g/pack) with fiber and specific ingredients (leucine, EPA and DHA, and beta-glucans) (enhanced-ONS) versus an isocaloric and isoproteic formula (standard-ONS) without specific ingredients...
January 10, 2024: Nutrition
https://read.qxmd.com/read/38338593/investigation-on-the-efficacy-of-two-food-supplements-containing-a-fixed-combination-of-selected-probiotics-and-%C3%AE-glucans-or-elderberry-extract-for-the-immune-system-modulation-on-cytokines-expression-in-human-thp-1-and-pbmc
#22
JOURNAL ARTICLE
Giorgio Cappellucci, Giulia Baini, Elisabetta Miraldi, Lara Pauletto, Heide De Togni, Floriana Raso, Marco Biagi
Several herbal and other natural products are used as ingredients in food supplements to strengthen immunity even if, very often, marketed products are proposed without a clear rationale or experimental evidence. In this study, we aimed to investigate the effect on human monocytes (THP-1) and on ex vivo human peripheral blood mononuclear cells (PBMC) of two formulations, one containing Bifidobacterium animalis subsp . lactis Bl-04® with β-glucans (for adults) and one containing Lactobacillus rhamnosus CRL1505 with elderberry extract (for children)...
February 1, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38328439/microbiota-modulation-by-dietary-oat-beta-glucan-prevents-steatotic-liver-disease-progression
#23
JOURNAL ARTICLE
Julius W Jaeger, Annette Brandt, Wenfang Gui, Timur Yergaliyev, Angélica Hernández-Arriaga, Mukil Marutha Muthu, Karolina Edlund, Ahmed Elashy, Antonio Molinaro, Diana Möckel, Jan Sarges, Emina Halibasic, Michael Trauner, Florian Kahles, Ulrike Rolle-Kampczyk, Jan Hengstler, Carolin Victoria Schneider, Twan Lammers, Hanns-Ulrich Marschall, Martin von Bergen, Amélia Camarinha-Silva, Ina Bergheim, Christian Trautwein, Kai Markus Schneider
BACKGROUND & AIMS: Changes in gut microbiota in metabolic dysfunction-associated steatotic liver disease (MASLD) are important drivers of disease progression towards fibrosis. Therefore, reversing microbial alterations could ameliorate MASLD progression. Oat beta-glucan, a non-digestible polysaccharide, has shown promising therapeutic effects on hyperlipidemia associated with MASLD, but its impact on gut microbiota and most importantly MASLD-related fibrosis remains unknown. METHODS: We performed detailed metabolic phenotyping, including assessments of body composition, glucose tolerance, and lipid metabolism, as well as comprehensive characterization of the gut-liver axis in a western-style diet (WSD)-induced model of MASLD and assessed the effect of a beta-glucan intervention on early and advanced liver disease...
March 2024: JHEP reports: innovation in hepatology
https://read.qxmd.com/read/38326203/plasma-concentration-of-antifungal-agent-micafungin-for-pediatric-living-donor-liver-transplantation
#24
JOURNAL ARTICLE
Takehisa Ueno, Koki Takase, Koichi Deguchi, Motonari Nomura, Miho Watanabe, Masafumi Kamiyama, Yuko Tazuke, Takeshi Kimura, Hiroomi Okuyama
BACKGROUND: Pediatric living-donor liver transplantation (LDLT) candidates often receive long-term antibiotic treatment. Micafungin has been used as an antifungal agent after LDLT, but the adequate dose after pediatric LDLT was unknown. Here, we report micafungin blood concentrations after pediatric LDLT and discuss its safety and adequate dosing. METHODS: Pediatric patients with data on micafungin concentrations after LDLT were identified. Those with surgical complications were excluded...
February 6, 2024: Transplantation Proceedings
https://read.qxmd.com/read/38311343/the-first-crystal-structure-of-a-family-45-glycoside-hydrolase-from-a-brown-rot-fungus-gloeophyllum-trabeum-gtcel45a
#25
JOURNAL ARTICLE
Laura Okmane, Louise Fitkin, Mats Sandgren, Jerry Ståhlberg
Here we describe the first crystal structure of a beta-1,4-endoglucanase from a brown-rot fungus, Gloeophyllum trabeum GtCel45A, which belongs to subfamily C of glycoside hydrolase family 45 (GH45). GtCel45A is ~ 18 kDa in size and the crystal structure contains 179 amino acids. The structure is refined at 1.30 Å resolution and Rfree 0.18. The enzyme consists of a single catalytic module folded into a six-stranded double-psi beta-barrel domain surrounded by long loops. GtCel45A is very similar in sequence (82% identity) and structure to PcCel45A from the white-rot fungus Phanerochaete chrysosporium...
February 4, 2024: FEBS Open Bio
https://read.qxmd.com/read/38309915/exploring-the-dynamics-of-bioactive-metabolites-changes-in-barley-grains-hordeum-vulgare-l-during-roasting-insights-from-uplc-qqq-ms-ms-analysis-combined-to-chemometrics
#26
JOURNAL ARTICLE
Eman Shawky, Samar M Bassam, Hanan S Marzouk, Doaa A Ghareeb, Samah M El Sohafy
This investigation delves into the dynamic metabolic shifts within barley grains during the roasting process, employing UPLC-QqQ-MS/MS analysis. The complex spectrum of metabolites before and after roasting is revealed. The resulting data, unveils substantial transformations in chemical composition during roasting. A total of 62 chromatographic peaks spanning phenolic compounds, flavones, Millard Reaction Products, amino acids, lignans, vitamins, folates, and anthocyanins were annotated. Leveraging UPLC-QqQ-MS/MS analysis, we scrutinized the intricate metabolite profile before and after roasting where the roasting process was found to trigger dynamic changes across diverse metabolite classes particularly Millard Reaction Products, produced through the Maillard reaction, with dihydro-5-methyl-5H-cyclopentapyrazine, maltol and hydroxy maltol emerging as discerning markers of roasting progression...
February 2024: Food Research International
https://read.qxmd.com/read/38276031/associations-between-genomic-variants-and-antifungal-susceptibilities-in-the-archived-global-candida-auris-population
#27
JOURNAL ARTICLE
Yue Wang, Jianping Xu
Candida auris is a recently emerged human fungal pathogen that has posed a significant threat to public health. Since its first identification in 2009, this fungus has caused nosocomial infections in over 47 countries across all inhabited continents. As of May 2023, the whole-genome sequences of over 4000 strains have been reported and a diversity of mutations, including in genes known to be associated with drug resistance in other human fungal pathogens, have been described. Among them, 387 strains contained antifungal-susceptibility information for which different methods might be used depending on the drugs and/or investigators...
January 22, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38275642/supplementation-with-complex-dietary-fiber-during-late-pregnancy-and-lactation-can-improve-progeny-growth-performance-by-regulating-maternal-antioxidant-status-and-milk-quality
#28
JOURNAL ARTICLE
Xinyu Liu, Xinke Wei, Ye Feng, Huawei Liu, Jiaqi Tang, Feng Gao, Baoming Shi
This study investigated the nutritional benefits of complex dietary fiber (beta-glucan and fructo-oligosaccharides, CDF) supplementation in sows and piglets during late pregnancy and lactation. Twenty-four sows were randomly divided into two groups: the control group was fed a basal diet ( n = 12), and the experimental group was fed a CDF diet (0.25% CDF replaced the same proportion of corn in the basal diet, n = 12). Dietary treatment was given from day 107 of pregnancy to day 25 of lactation. The results of this experiment showed that CDF increased the average daily feed intake (ADFI) of sows during lactation and the weaning body weight (BW) and average daily gain of piglets...
December 21, 2023: Antioxidants (Basel, Switzerland)
https://read.qxmd.com/read/38257940/effects-of-increasing-levels-of-purified-beta-1-3-1-6-glucans-on-the-fecal-microbiome-digestibility-and-immunity-variables-of-healthy-adult-dogs
#29
JOURNAL ARTICLE
Pedro Henrique Marchi, Thiago Henrique Annibale Vendramini, Rafael Vessecchi Amorim Zafalon, Leonardo de Andrade Príncipe, Cinthia Gonçalves Lenz Cesar, Mariana Pamplona Perini, Thaila Cristina Putarov, Cristina Oliveira Massoco Salles Gomes, Júlio Cesar de Carvalho Balieiro, Marcio Antonio Brunetto
Yeast-purified beta-1,3/1,6-glucans (BG) can modulate dogs' immune systems and microbiome, but the optimal inclusion dose remains unknown. The aim of the study was to evaluate the effects of 0.0, 0.07, 0.14, and 0.28% inclusion of BG in a dry extruded diet on the digestibility, immunity, and fecal microbiota of healthy adult dogs. Eight male and female border collies [n = 4; body condition score (BCS) = 5] and English cocker spaniels (n = 4; BCS = 5), aged 3.5 ± 0.5 years, were randomly distributed into two 4 × 4 balanced Latin squares...
January 5, 2024: Microorganisms
https://read.qxmd.com/read/38255195/-aedes-aegypti-beta-1-3-glucan-binding-protein-inhibits-dengue-and-zika-virus-replication
#30
JOURNAL ARTICLE
Xiaoxue Xie, Di Wang, Bo Li, Guorui Liang, Xiaoli Chen, Dan Xing, Teng Zhao, Xinyu Zhou, Chunxiao Li
GNBPB6, a beta-1,3-glucan-binding protein, was identified in the transcriptome of Aedes aegypti ( A. aegypti ) with dengue (DENV), Zika (ZIKV), and chikungunya viruses (CHIKV). In this study, we not only clarified that DENV2 and ZIKV regulate the changes in GNBPB6 expression but also identified the relationship of this gene with viral infections. The changes in GNBPB6 expression were quantified and showed a decrease in A. aegypti cells (Aag2 cells) at 2 dpi and 3 dpi and an increase at 4 dpi and 5 dpi ( p < 0...
January 1, 2024: Biomedicines
https://read.qxmd.com/read/38251046/current-views-about-the-inflammatory-damage-triggered-by-bacterial-superantigens-and-experimental-attempts-to-neutralize-superantigen-mediated-toxic-effects-with-natural-and-biological-products
#31
REVIEW
Luigi Santacroce, Skender Topi, Ioannis Alexandros Charitos, Roberto Lovero, Paolo Luperto, Raffaele Palmirotta, Emilio Jirillo
Superantigens, i.e., staphylococcal enterotoxins and toxic shock syndrome toxin-1, interact with T cells in a different manner in comparison to conventional antigens. In fact, they activate a larger contingent of T lymphocytes, binding outside the peptide-binding groove of the major histocompatibility complex class II. Involvement of many T cells by superantigens leads to a massive release of pro-inflammatory cytokines, such as interleukin (IL)-1, IL-2, IL-6, tumor necrosis factor-alpha and interferon-gamma...
January 9, 2024: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://read.qxmd.com/read/38247477/dietary-%C3%AE-glucan-alleviates-antibiotic-associated-side-effects-by-increasing-the-levels-of-antioxidant-enzyme-activities-and-modifying-intestinal-microbiota-in-pacific-white-shrimp-litopenaeus-vannamei
#32
JOURNAL ARTICLE
Yanbing Qiao, Fenglu Han, Xuhan Peng, Artur Rombenso, Erchao Li
Antibiotics and their secondary metabolites are commonly found in aquatic ecosystems, leading to the passive exposure of many aquatic animals to low doses of antibiotics, which can affect their health. However, there is limited information available on how to mitigate the side effects of antibiotics on normal aquatic animals. This study aimed to investigate the potential of dietary β-glucan to alleviate the side effects induced by antibiotics in Pacific white shrimp ( Litopenaeus vannamei ) (0.37 ± 0...
December 28, 2023: Antioxidants (Basel, Switzerland)
https://read.qxmd.com/read/38247312/effect-of-beta-glucan-coating-on-controlled-release-bioaccessibility-and-absorption-of-%C3%AE-carotene-from-loaded-liposomes
#33
JOURNAL ARTICLE
Taskeen Niaz, Alan Mackie
Recently, the use of biopolymers as coating material to stabilise phospholipid-based nanocarriers has increased. One such class of biopolymers is the dietary fibre beta-glucan (βG). In this study, we developed and characterized beta-carotene (βC) loaded βG coated nanoliposomes (GNLs) to investigate the effect of βG coating on the stability, controlled release, bioaccessibility, diffusion and subsequent absorption of the lipophilic active agent. The size, charge ( Z -potential), and FTIR spectra were measured to determine the physicochemical stability of GNLs...
January 22, 2024: Food & Function
https://read.qxmd.com/read/38229865/current-technologies-and-future-perspective-in-meat-analogs-made-from-plant-insect-and-mycoprotein-materials-a-review
#34
REVIEW
Da Young Lee, Seung Yun Lee, Seung Hyeon Yun, Juhyun Lee, Ermie Mariano, Jinmo Park, Yeongwoo Choi, Dahee Han, Jin Soo Kim, Sun Jin Hur
This study reviewed the current data presented in the literature on developing meat analogs using plant-, insect-, and protein-derived materials and presents a conclusion on future perspectives. As a result of this study, it was found that the current products developed using plant-, insect-, and mycoprotein-derived materials still did not provide the quality of traditional meat products. Plant-derived meat analogs have been shown to use soybean-derived materials and beta-glucan or gluten, while insect-derived materials have been studied by mixing them with plant-derived materials...
January 2024: Food science of animal resources
https://read.qxmd.com/read/38228404/deep-cutaneous-mycoses-in-kidney-transplant-recipients-diagnostic-and-therapeutic-challenges
#35
JOURNAL ARTICLE
Chloé Bertin, Emilie Sitterlé, Anne Scemla, Sylvie Fraitag, Sarah Delliere, Sarah Guegan, Dea Garcia Hermoso, Stéphanie Leclerc-Mercier, Claire Rouzaud, Fanny Lanternier, Marie-Elisabeth Bougnoux
Deep cutaneous mycoses (DCMs) are rare infections that extend throughout the dermis and subcutis, often occurring after inoculation with pathogenic fungi. Trends toward a growing incidence have been observed that may be partially related to an increasing population of solid organ transplant patients. The aim of this study is to describe the diagnostic and the outcomes of DCM among kidney transplant recipients so as to optimize their management. We performed a retrospective review of cases of DCM occurring among kidney transplant recipients in our institution over 12 years...
January 16, 2024: Medical Mycology
https://read.qxmd.com/read/38220355/effect-of-chemical-thermal-and-enzymatic-processing-of-wheat-bran-on-the-solubilization-technological-and-biological-properties-of-non-starch-polysaccharides
#36
JOURNAL ARTICLE
Candela Paesani, Tamy C G L Lammers, Lorena S Sciarini, Malena Moiraghi, Gabriela T Pérez, João Paulo Fabi
Wheat bran is a low-cost by-product with significant nutritional value, but it is primarily utilized in animal feed applications. This study sought to investigate chemical methodologies for modifying the wheat bran's structure, enhancing non-starch polysaccharides solubility in water, and assessing alterations in functional and biological attributes. Chemical modifications were conducted under aqueous, alkaline, acid, and oxidizing conditions. Parameters such as yield, monosaccharides, arabinoxylans, β-glucan and phenolic content, molecular weight, functional properties, and prebiotic in vitro capacity were examined...
March 15, 2024: Carbohydrate Polymers
https://read.qxmd.com/read/38154453/the-effect-of-enzymatic-treatment-with-mutanase-beta-glucanase-and-dnase-on-a-saliva-derived-biofilm-model
#37
JOURNAL ARTICLE
Pernille Dukanovic Rikvold, Lea Benedicte Hansen Skov, Rikke Louise Meyer, Mette Rose Jorgensen, Manish K Tiwari, Sebastian Schlafer
INTRODUCTION: The dental biofilm matrix is an important determinant of virulence for caries development and comprises a variety of extracellular polymeric substances that contribute to biofilm stability. Enzymes that break down matrix components may be a promising approach to caries control, and in light of the compositional complexity of the dental biofilm matrix, treatment with multiple enzymes may enhance the reduction of biofilm formation compared to single enzyme therapy. The present study investigated the effect of the three matrix-degrading enzymes mutanase, beta-glucanase and DNase, applied separately or in combinations, on biofilm prevention and removal in a saliva-derived in vitro-grown model...
December 28, 2023: Caries Research
https://read.qxmd.com/read/38143818/effects-of-long-term-administration-of-various-dietary-prebiotic-supplements-on-the-growth-immune-cell-activity-and-digestive-tract-histology-of-juvenile-vimba-vimba-vimba
#38
JOURNAL ARTICLE
Barbara Kazuń, Krzysztof Kazuń, Joanna Małaczewska, Rafał Kamiński, Dobrochna Adamek-Urbańska, Justyna Sikorska, Jacek Wolnicki, Hubert Szudrowicz
INTRODUCTION: The experiment was set to determine the effects of long-term (55-day) use of three commercial prebiotics including Saccharomyces cerevisiae -derived β-glucans and one including inulin on juvenile vimba (Vimba vimba) reared intensively under controlled conditions. MATERIAL AND METHODS: Six-month-old fish were fed commercial feed (Control group, n = 90), or the same feed supplemented with 0.02% Leiber Beta-S (BS group, n = 90), 0.20% Biolex MB40 (MB group, n = 90), 0...
June 2023: Journal of Veterinary Research
https://read.qxmd.com/read/38140486/genome-wide-identification-of-callose-synthase-family-genes-and-their-expression-analysis-in-floral-bud-development-and-hormonal-responses-in-prunus-mume
#39
JOURNAL ARTICLE
Man Zhang, Wenhui Cheng, Jia Wang, Tangren Cheng, Xinlian Lin, Qixiang Zhang, Cuiling Li
Callose is an important polysaccharide composed of beta-1,3-glucans and is widely implicated in plant development and defense responses. Callose synthesis is mainly catalyzed by a family of callose synthases, also known as glucan synthase-like (GSL) enzymes. Despite the fact that GSL family genes were studied in a few plant species, their functional roles have not been fully understood in woody perennials. In this study, we identified total of 84 GSL genes in seven plant species and classified them into six phylogenetic clades...
December 14, 2023: Plants (Basel, Switzerland)
https://read.qxmd.com/read/38136815/effects-of-dietary-%C3%AE-glucan-feeding-strategy-on-the-growth-physiological-response-and-gut-microbiota-of-pacific-white-shrimp-litopenaeus-vannamei-under-low-salinity
#40
JOURNAL ARTICLE
Yanbing Qiao, Fenglu Han, Kunyu Lu, Li Zhou, Artur Rombenso, Erchao Li
An eight-week feeding trial was conducted to investigate the effects of a dietary β-glucan application strategy on the growth performance, physiological response, and gut microbiota of Pacific white shrimp ( Litopenaeus vannamei ) (0.49 ± 0.17 g) under low salinity. Six feeding strategies were established, including a continuous β-glucan-free diet group (control), a continuously fed group with a 0.1% β-glucan diet (T1), and groups with the following intermittent feeding patterns: 1 day of β-glucan diet and 6 days of β-glucan-free diet (T2), 2 days of β-glucan diet and 5 days of β-glucan-free diet (T3), 3 days of β-glucan diet and 4 days of β-glucan-free diet (T4), and 4 days of β-glucan diet and 3 days of β-glucan-free diet (T5) each week...
December 7, 2023: Animals: An Open Access Journal From MDPI
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