keyword
https://read.qxmd.com/read/38533456/diving-into-the-zebrafish-brain-exploring-neuroscience-frontiers-with-genetic-tools-imaging-techniques-and-behavioral-insights
#21
REVIEW
O Doszyn, T Dulski, J Zmorzynska
The zebrafish ( Danio rerio ) is increasingly used in neuroscience research. Zebrafish are relatively easy to maintain, and their high fecundity makes them suitable for high-throughput experiments. Their small, transparent embryos and larvae allow for easy microscopic imaging of the developing brain. Zebrafish also share a high degree of genetic similarity with humans, and are amenable to genetic manipulation techniques, such as gene knockdown, knockout, or knock-in, which allows researchers to study the role of specific genes relevant to human brain development, function, and disease...
2024: Frontiers in Molecular Neuroscience
https://read.qxmd.com/read/38533453/inter-individual-variations-in-circadian-misalignment-induced-nafld-pathophysiology-in-mice
#22
JOURNAL ARTICLE
Nobuya Koike, Yasuhiro Umemura, Hitoshi Inokawa, Isao Tokuda, Yoshiki Tsuchiya, Yuh Sasawaki, Atsushi Umemura, Naoko Masuzawa, Kazuya Yabumoto, Takashi Seya, Akira Sugimoto, Seung-Hee Yoo, Zheng Chen, Kazuhiro Yagita
Pathological consequences of circadian misalignment, such as shift work, show considerable individual differences, but the lack of mechanistic understanding hinders precision prevention to prevent and mitigate disease symptoms. Here, we employed an integrative approach involving physiological, transcriptional, and histological phenotypes to examine inter-individual differences in pre-symptomatic pathological progression, preceding irreversible disease onset, in wild-type mice exposed to chronic jet-lag (CJL)...
February 16, 2024: IScience
https://read.qxmd.com/read/38533447/research-on-adults-with-subthreshold-depression-after-aerobic-exercise-a-resting-state-fmri-study-based-on-regional-homogeneity-reho
#23
JOURNAL ARTICLE
Wenbin Shen, Xiaoxiao Wang, Qin Li, Qingguo Ding, Hongqiang Zhang, Zheng Qian, Zhixin Sun, Xingyu Chen, Jun Zhang, Mengqi Zhao, Lina Huang, Wei Xing
OBJECTIVE: Subthreshold depression (StD)/subsyndromal depression refers to a threatening precursor to depression. Aerobic exercise is a promising self-supportive adjunctive intervention and an effective measure for StD. Our study utilizes regional homogeneity (ReHo) to investigate the impact of aerobic exercise on resting-state brain function. METHODS: A total of 78 subjects, aged between 18 and 48 years, (StD group, n = 44; healthy control (HC) group, n = 34) engaged in moderate-intensity aerobic exercise 3-4 times per week for 8 weeks...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38533446/higher-serum-lp-pla2-is-associated-with-cognitive-impairment-in-parkinson-s-disease-patients
#24
JOURNAL ARTICLE
Zubo Wu, Defeng Shu, Suyuan Wu, Pengcheng Cai, Tao Liang
OBJECTIVE: To explore the association between lipoprotein-associated phospholipase A2 (Lp-PLA2) and the risk of cognitive impairment in Parkinson's disease (PD-CI). METHODS: A case-control study involving 100 hospitalized PD patients and 60 healthy controls was carried out. Serum Lp-PLA2 level was detected by automatic biochemical analyzer. Based on whether Parkinson's patients have cognitive impairment, PD patients were subdivided to analyze the clinical value of Lp-PLA2...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38533445/a-study-on-eeg-differences-between-active-counting-and-focused-breathing-tasks-for-more-sensitive-detection-of-consciousness
#25
JOURNAL ARTICLE
Yimeng You, Yahui Li, Baobao Yu, Ankai Ying, Huilin Zhou, Guokun Zuo, Jialin Xu
INTRODUCTION: In studies on consciousness detection for patients with disorders of consciousness, difference comparison of EEG responses based on active and passive task modes is difficult to sensitively detect patients' consciousness, while a single potential analysis of EEG responses cannot comprehensively and accurately determine patients' consciousness status. Therefore, in this paper, we designed a new consciousness detection paradigm based on a multi-stage cognitive task that could induce a series of event-related potentials and ERD/ERS phenomena reflecting different consciousness contents...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38533444/small-size-big-problems-insights-and-difficulties-in-prenatal-diagnosis-of-fetal-microcephaly
#26
REVIEW
Leila Haddad, Efrat Hadi, Zvi Leibovitz, Dorit Lev, Yoseph Shalev, Liat Gindes, Tally Lerman-Sagie
Microcephaly is a sign, not a diagnosis. Its incidence varies widely due to the differences in the definition and the population being studied. It is strongly related to neurodevelopmental disorders. Differences in definitions and measurement techniques between fetuses and newborns pose a great challenge for the diagnosis and prognostication of fetal microcephaly. A false positive diagnosis can result (in countries where it is legal) in erroneous termination of pregnancy, where a false negative diagnosis might lead to the birth of a microcephalic newborn...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38533425/analyzing-changes-in-parkinsonian-speech-over-time-a-diachronic-experimental-phonetics-study
#27
JOURNAL ARTICLE
Massimo Pettorino, Marta Maffia
In this contribution the use of web resources for the longitudinal study of speech rhythm of a 'well-known' person diagnosed with Parkinson's disease, the American actor Alan Alda, is proposed. A corpus of 20 speech samples produced in the period between 1979 and 2021 was collected from the web. A rhythmical analysis was conducted, based on two parameters: the percentage of vocalic portion on the total duration of the utterance (%V) and the VtoV, the mean duration of the interval between two consecutive vowel onset points...
2024: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/38533420/an-eye-on-semantics-a-study-on-the-influence-of-concreteness-and-predictability-on-early-fixation-durations
#28
JOURNAL ARTICLE
Federica Magnabosco, Olaf Hauk
We used eye-tracking during natural reading to study how semantic control and representation mechanisms interact for the successful comprehension of sentences, by manipulating sentence context and single-word meaning. Specifically, we examined whether a word's semantic characteristic (concreteness) affects first fixation and gaze durations (FFDs and GDs) and whether it interacts with the predictability of a word. We used a linear mixed effects model including several possible psycholinguistic covariates. We found a small but reliable main effect of concreteness and replicated a predictability effect on FFDs, but we found no interaction between the two...
2024: Language, Cognition and Neuroscience
https://read.qxmd.com/read/38533314/differential-contributions-of-body-form-motion-and-temporal-information-to-subjective-action-understanding-in-naturalistic-stimuli
#29
JOURNAL ARTICLE
Vojtěch Smekal, Marta Poyo Solanas, Evelyne I C Fraats, Beatrice de Gelder
INTRODUCTION: We investigated the factors underlying naturalistic action recognition and understanding, as well as the errors occurring during recognition failures. METHODS: Participants saw full-light stimuli of ten different whole-body actions presented in three different conditions: as normal videos, as videos with the temporal order of the frames scrambled, and as single static representative frames. After each stimulus presentation participants completed one of two tasks-a forced choice task where they were given the ten potential action labels as options, or a free description task, where they could describe the action performed in each stimulus in their own words...
2024: Frontiers in Integrative Neuroscience
https://read.qxmd.com/read/38533115/neurobiosense-a-multidimensional-dataset-for-neuromarketing-analysis
#30
JOURNAL ARTICLE
Büşra Kocaçınar, Pelin İnan, Ela Nur Zamur, Buket Çalşimşek, Fatma Patlar Akbulut, Cagatay Catal
In the context of neuromarketing, sales, and branding, the investigation of consumer decision-making processes presents complex and intriguing challenges. Consideration of the effects of multicultural influences and societal conditions from a global perspective enriches this multifaceted field. The application of neuroscience tools and techniques to international marketing and consumer behavior is an emerging interdisciplinary field that seeks to understand the cognitive processes, reactions, and selection mechanisms of consumers within the context of branding and sales...
April 2024: Data in Brief
https://read.qxmd.com/read/38533112/a-simultaneous-eeg-fnirs-dataset-of-the-visual-cognitive-motivation-study-in-healthy-adults
#31
JOURNAL ARTICLE
Tustanah Phukhachee, Thanate Angsuwatanakul, Keiji Iramina, Boonserm Kaewkamnerdpong
This article described a publicly available dataset of the visual cognitive motivation study in healthy adults. To gain an in-depth understanding and insights into motivation, Electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) were measured simultaneously at shared locations while participants performed a visual cognitive motivation task. The participants' choices in the cognitive motivation task were recorded. The effects of their motivation were identified in the recognition test afterward...
April 2024: Data in Brief
https://read.qxmd.com/read/38533067/validation-of-the-italian-version-of-the-neuroception-of-psychological-safety-scale-npss
#32
JOURNAL ARTICLE
Andrea Poli, Mario Miccoli
Research on the neuroscience of fear in both humans and non-humans has suggested that a lack of acquisition of safety cues might be a biological hallmark of posttraumatic stress disorder (PTSD). Danger perception, and in particular, feeling as one's own life is in danger, is thought to represent a major predictor of PTSD. Persistent danger perception is concurrently associated with a persistence of lack of safety. However, despite several research efforts, no validated psychometric tools exist regarding psychological safety as a unique core construct in the domain of a soothing-contentment system...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38532986/a-theory-of-the-neural-mechanisms-underlying-negative-cognitive-bias-in-major-depression
#33
JOURNAL ARTICLE
Yuyue Jiang
The widely acknowledged cognitive theory of depression, developed by Aaron Beck, focused on biased information processing that emphasizes the negative aspects of affective and conceptual information. Current attempts to discover the neurological mechanism underlying such cognitive and affective bias have successfully identified various brain regions associated with severally biased functions such as emotion, attention, rumination, and inhibition control. However, the neurobiological mechanisms of how individuals in depression develop this selective processing toward negative is still under question...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38532984/editorial-plasticity-and-flexibility-in-the-parental-brain
#34
EDITORIAL
Natalia Uriarte, Mariana Pereira
No abstract text is available yet for this article.
2024: Frontiers in Behavioral Neuroscience
https://read.qxmd.com/read/38532887/emergence-of-complex-oscillatory-dynamics-in-the-neuronal-networks-with-long-activity-time-of-inhibitory-synapses
#35
JOURNAL ARTICLE
Mozhgan Khanjanianpak, Nahid Azimi-Tafreshi, Alireza Valizadeh
The brain displays complex dynamics, including collective oscillations, and extensive research has been conducted to understand their generation. However, our understanding of how biological constraints influence these oscillations is incomplete. This study investigates the essential properties of neuronal networks needed to generate oscillations resembling those in the brain. A simple discrete-time model of interconnected excitable elements is developed, capable of closely resembling the complex oscillations observed in biological neural networks...
April 19, 2024: IScience
https://read.qxmd.com/read/38532826/neuropathology-and-epilepsy-surgery-2024-update
#36
JOURNAL ARTICLE
Ingmar Blümcke
Neuropathology-based studies in neurosurgically resected brain tissue obtained from carefully examined patients with focal epilepsies remain a treasure box for excellent insights into human neuroscience, including avenues to better understand the neurobiology of human brain organization and neuronal hyperexcitability at the cellular level including glio-neuronal interaction. It also allows to translate results from animal models in order to develop personalized treatment strategies in the near future. A nice example of this is the discovery of a new disease entity in 2017, termed mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy or MOGHE, in the frontal lobe of young children with intractable seizures...
January 2024: Free neuropathology
https://read.qxmd.com/read/38532792/interpersonal-eye-tracking-reveals-the-dynamics-of-interacting-minds
#37
REVIEW
Sophie Wohltjen, Thalia Wheatley
The human eye is a rich source of information about where, when, and how we attend. Our gaze paths indicate where and what captures our attention, while changes in pupil size can signal surprise, revealing our expectations. Similarly, the pattern of our blinks suggests levels of alertness and when our attention shifts between external engagement and internal thought. During interactions with others, these cues reveal how we coordinate and share our mental states. To leverage these insights effectively, we need accurate, timely methods to observe these cues as they naturally unfold...
2024: Frontiers in Human Neuroscience
https://read.qxmd.com/read/38532791/global-sensitivity-of-eeg-source-analysis-to-tissue-conductivity-uncertainties
#38
JOURNAL ARTICLE
Johannes Vorwerk, Carsten H Wolters, Daniel Baumgarten
INTRODUCTION: To reliably solve the EEG inverse problem, accurate EEG forward solutions based on a detailed, individual volume conductor model of the head are essential. A crucial-but often neglected-aspect in generating a volume conductor model is the choice of the tissue conductivities, as these may vary from subject to subject. In this study, we investigate the sensitivity of EEG forward and inverse solutions to tissue conductivity uncertainties for sources distributed over the whole cortex surface...
2024: Frontiers in Human Neuroscience
https://read.qxmd.com/read/38532790/inter-brain-desynchronization-in-social-interaction-a-consequence-of-subjective-involvement
#39
JOURNAL ARTICLE
Tom Froese, Chen Lam Loh, Finda Putri
Hyperscanning approaches to human neuroscience aim to uncover the neural mechanisms of social interaction. They have been largely guided by the expectation that increased levels of engagement between two persons will be supported by higher levels of inter-brain synchrony (IBS). A common approach to measuring IBS is phase synchrony in the context of EEG hyperscanning. Yet the growing number of experimental findings does not yield a straightforward interpretation, which has prompted critical reflections about the field's theoretical and methodological principles...
2024: Frontiers in Human Neuroscience
https://read.qxmd.com/read/38532789/the-effect-of-reward-on-motor-learning-different-stage-different-effect
#40
REVIEW
Jingwang Zhao, Guanghu Zhang, Dongsheng Xu
Motor learning is a prominent and extensively studied subject in rehabilitation following various types of neurological disorders. Motor repair and rehabilitation often extend over months and years post-injury with a slow pace of recovery, particularly affecting the fine movements of the distal extremities. This extended period can diminish the motivation and persistence of patients, a facet that has historically been overlooked in motor learning until recent years. Reward, including monetary compensation, social praise, video gaming, music, and virtual reality, is currently garnering heightened attention for its potential to enhance motor motivation and improve function...
2024: Frontiers in Human Neuroscience
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