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https://www.readbyqxmd.com/read/28342409/perceived-health-and-alcohol-use-in-individuals-with-hiv-and-hepatitis-c-who-use-drugs
#1
Jennifer C Elliott, Deborah S Hasin, Don C Des Jarlais
BACKGROUND: Individuals who use illicit drugs are at heightened risk for HIV and/or Hepatitis C Virus (HCV). Despite the medical consequences of drinking for drug-using individuals with these infections, many do drink. In other studies, how individuals perceive their health relates to their engagement in risk behaviors such as drinking. However, among drug-using individuals with HIV and HCV, whether perceived health relates to drinking is unknown. OBJECTIVE: We examine the association between perceived health and drinking among drug-using individuals with HIV and/or HCV...
March 10, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28337798/latent-classes-of-polydrug-and-polyroute-use-and-associations-with-human-immunodeficiency-virus-risk-behaviours-and-overdose-among-people-who-inject-drugs-in-tijuana-baja-california-mexico
#2
Meredith C Meacham, Scott C Roesch, Steffanie A Strathdee, Suzanne Lindsay, Patricia Gonzalez-Zuniga, Tommi L Gaines
INTRODUCTION AND AIMS: Patterns of polydrug use among people who inject drugs (PWID) may be differentially associated with overdose and unique human immunodeficiency virus (HIV) risk factors. Subgroups of PWID in Tijuana, Mexico, were identified based on substances used, route of administration, frequency of use and co-injection indicators. DESIGN AND METHODS: Participants were PWID residing in Tijuana age ≥18 years sampled from 2011 to 2012 who reported injecting an illicit substance in the past month (n = 735)...
March 24, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28336000/high-intensity-cannabis-use-and-hiv-clinical-outcomes-among-hiv-positive-people-who-use-illicit-drugs-in-vancouver-canada
#3
Stephanie Lake, Thomas Kerr, Rielle Capler, Jeannie Shoveller, Julio Montaner, M-J Milloy
BACKGROUND: Reforms to the legal status of medical and non-medical cannabis are underway in many jurisdictions, including Canada, as are renewed efforts to scale-up HIV treatment-as-prevention (TasP) initiatives. It has been suggested that high-intensity cannabis use may be associated with sub-optimal HIV treatment outcomes. Thus, using data from a setting with a community-wide treatment-as-prevention (TasP) initiative coinciding with increasing access to medical cannabis, we sought to investigate the possible impact of high-intensity cannabis use on HIV clinical outcomes...
March 20, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28334661/extended-release-naltrexone-reduces-alcohol-consumption-among-released-prisoners-with-hiv-disease-as-they-transition-to-the-community
#4
Sandra A Springer, Angela Di Paola, Marwan M Azar, Russell Barbour, Archana Krishnan, Frederick L Altice
BACKGROUND: Alcohol use disorders (AUDs) are highly prevalent among persons living with HIV (PLH) within the criminal justice system (CJS). Extended-release naltrexone (XR-NTX) has not been previously evaluated among CJS-involved PLH with AUDs. METHODS: A randomized, double-blind, placebo-controlled trial was conducted among 100 HIV+ prisoners with AUDs. Participants were randomized 2:1 to receive 6 monthly injections of XR-NTX or placebo starting one week prior to release...
March 10, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28329652/the-inpatient-burden-of-psoriasis-a-nationwide-analysis
#5
Derek Y Hsu
Psoriasis is a chronic inflammatory skin disorder associated with substantial morbidity and mortality. Little is known about psoriasis in the inpatient setting. We sought to determine the inpatient burden of psoriasis in the US. We analyzed the 2002-2012 Nationwide Inpatient Sample, containing a representative 20% stratified sample of all hospitalizations in the US. Psoriasis was determined by a validated algorithm using ICD-9-CM codes. Demographics, inflation-adjusted cost, length of stay, comorbidities, and sex- adjusted mortality were analyzed using descriptive statistics and regression analysis...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28327789/prevalence-of-hepatitis-c-virus-and-human-immunodeficiency-virus-in-a-group-of-patients-newly-diagnosed-with-active-tuberculosis-in-porto-alegre-southern-brazil
#6
Cintia Costi, Tarciana Grandi, Maria Laura Halon, Márcia Susana Nunes Silva, Cláudia Maria Dornelles da Silva, Tatiana Schäffer Gregianini, Lia Gonçalves Possuelo, Carla Adriane Jarczewski, Christian Niel, Maria Lucia Rosa Rossetti
BACKGROUND: Porto Alegre is the Brazilian state capital with second highest incidence of tuberculosis (TB) and the highest proportion of people infected with human immunodeficiency virus (HIV) among patients with TB. Hepatitis C virus (HCV) infection increases the risk of anti-TB drug-induced hepatotoxicity, which may result in discontinuation of the therapy. OBJECTIVES: The aim of this study was (i) to estimate prevalence of HCV and HIV in a group of patients newly diagnosed with active TB in a public reference hospital in Porto Alegre and (ii) to compare demographic, behavioural, and clinical characteristics of patients in relation to their HCV infection status...
April 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28324813/among-patients-with-unhealthy-alcohol-use-those-with-hiv-are-less-likely-than-those-without-to-receive-evidence-based-alcohol-related-care-a-national-va-study
#7
Emily C Williams, Gwen T Lapham, Susan M Shortreed, Anna D Rubinsky, Jennifer F Bobb, Kara M Bensley, Sheryl L Catz, Julie E Richards, Katharine A Bradley
BACKGROUND: Alcohol use has important adverse effects on people living with HIV (PLWH). This study of patients with recognized unhealthy alcohol use estimated and compared rates of alcohol-related care received by PLWH and HIV- patients. METHODS: Outpatients from the Veterans Health Administration who had one or more positive screen(s) for unhealthy alcohol use (AUDIT-C≥5) documented in their medical records 10/2009-5/2013 were eligible. Primary and secondary outcomes were brief intervention documented ≤14days after a positive alcohol screen, and a composite measure of any alcohol-related care (brief intervention, specialty addictions treatment or pharmacotherapy documented ≤365 days), respectively...
March 6, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28324675/arterial-stiffness-in-hiv-infected-youth-and-associations-with-hiv-related-variables
#8
Allison Ross Eckard, Paolo Raggi, Joshua H Ruff, Mary Ann O'Riordan, Julia C Rosebush, Danielle Labbato, Julie E Daniels, Monika Uribe-Leitz, Christopher T Longencker, Grace A McComsey
Children and young adults infected with HIV are at elevated risk for cardiovascular disease (CVD). However, scarce data exist on the utility of non-invasive methods to diagnose subclinical CVD, such as pulse wave velocity (PWV), a non-invasive measure of arterial stiffness. The objectives of this study were to assess the relationship of carotid-femoral PWV with subclinical atherosclerosis measured by carotid intima-media thickness (IMT), compare measurements to healthy controls, and evaluate variables associated with PWV in HIV-infected youth...
March 21, 2017: Virulence
https://www.readbyqxmd.com/read/28320796/effect-of-alcohol-consumption-and-psychosocial-stressors-on-preterm-and-small-for-gestational-age-births-in-hiv-infected-women-in-south-africa-a-cohort-study
#9
Ayesha Sania, Kirsty Brittain, Tamsin K Phillips, Allison Zerbe, Agnes Ronan, Landon Myer, Elaine J Abrams
OBJECTIVES: Psychosocial stressors such as depression and stress, intimate partner violence (IPV) and alcohol use have been linked to preterm and small-for-gestational-age (SGA) births in general populations. The prevalence of psychosocial stressors and alcohol abuse is high in many HIV-infected (HIV+) populations. Our objective was to evaluate the effects of psychosocial stressors and alcohol abuse on birth outcomes in HIV-infected women. METHODS: Antenatal depression and non-specific psychological distress, periconception IPV and alcohol consumption were measured during the second trimester among HIV+ women initiating antiretroviral treatment with efavirenz + emtricitibine + tenofovir in Cape Town, South Africa...
March 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28301592/psychosocial-correlates-of-nutritional-status-among-people-living-with-hiv-on-antiretroviral-therapy-a-matched-case-control-study-in-central-zone-of-tigray-northern-ethiopia
#10
Negassie Berhe Weldehaweria, Elsa Hagos Abreha, Meresa Gebremedhin Weldu, Kebede Haile Misgina
BACKGROUND: Malnutrition hastens progression to Acquired Human Immunodeficiency Syndromes (AIDS) related illnesses; undermines adherence and response to antiretroviral therapy (ART) in resource-poor settings. However, nutritional status of people living with HIV (PLHIV) can be affected by various psychosocial factors which have not been well explored in Ethiopia. Therefore, the objective of this study was to determine psychosocial correlates of nutritional status among people living with HIV (PLHIV) on ART in Central zone of Tigray, Northern Ethiopia...
2017: PloS One
https://www.readbyqxmd.com/read/28295416/validating-harmful-alcohol-use-as-a-phenotype-for-genetic-discovery-using-phosphatidylethanol-and-a-polymorphism-in-adh1b
#11
Amy C Justice, Kathleen A McGinnis, Jan Tate, Ke Xu, William C Becker, Hongyu Zhao, Joel Gelernter, Henry R Kranzler
BACKGROUND: Although alcohol risk is heritable, few genetic risk variants have been identified. Longitudinal (EHR) data offer a largely untapped source of phenotypic information for genetic studies, but EHR-derived phenotypes for harmful alcohol exposure have yet to be validated. Using a variant of known effect, we used electronic health record (EHR) data to develop and validate a phenotype for harmful alcohol exposure that can be used to identify unknown genetic variants in large samples...
March 11, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28285434/prevalence-and-factors-associated-with-hazardous-alcohol-use-among-persons-living-with-hiv-across-the-us-in-the-current-era-of-antiretroviral-treatment
#12
Heidi M Crane, Mary E McCaul, Geetanjali Chander, Heidi Hutton, Robin M Nance, Joseph A C Delaney, Joseph O Merrill, Bryan Lau, Kenneth H Mayer, Michael J Mugavero, Matthew Mimiaga, James H Willig, Greer A Burkholder, Daniel R Drozd, Rob J Fredericksen, Karen Cropsey, Richard D Moore, Jane M Simoni, W Christopher Mathews, Joseph J Eron, Sonia Napravnik, Katerina Christopoulos, Elvin Geng, Michael S Saag, Mari M Kitahata
Hazardous alcohol use is associated with detrimental health outcomes among persons living with HIV (PLWH). We examined the prevalence and factors associated with hazardous alcohol use in the current era using several hazardous drinking definitions and binge drinking defined as ≥5 drinks for men versus ≥4 for women. We included 8567 PLWH from 7 U.S. sites from 2013 to 2015. Current hazardous alcohol use was reported by 27% and 34% reported binge drinking. In adjusted analyses, current and past cocaine/crack (odd ratio [OR] 4...
March 11, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28280398/interrelationship-of-hepatitis-c-virus-genotypes-with-patient-characteristics-in-bahrain
#13
Maheeba A Abdulla, Eman A Murad, Hend A Aljenaidi, Duha R Aljowder, Omar Ik Aljeeran, Eman Farid, Jehad R Al Qamish
AIM: Hepatitis C virus (HCV) shows genotype-based variation in prevalence across geographical regions. This study was conducted to understand the clinical interrelationship of HCV genotypes with patient characteristics. METHODS: Medical records of 122 patients positive for HCV RNA test collected during 2013 and 2014 were included for analysis. Only adults were included in the study. HCV RNA extraction and genotyping was done as part of the routine diagnostic requirements...
2017: Hepatic Medicine: Evidence and Research
https://www.readbyqxmd.com/read/28278568/phosphatidylethanol-confirmed-alcohol-use-among-art-na%C3%A3-ve-hiv-infected-persons-who-denied-consumption-in-rural-uganda
#14
Winnie R Muyindike, Christine Lloyd-Travaglini, Robin Fatch, Nneka I Emenyonu, Julian Adong, Christine Ngabirano, Debbie M Cheng, Michael R Winter, Jeffrey H Samet, Judith A Hahn
Under-reporting of alcohol use by HIV-infected patients could adversely impact clinical care. This study examined factors associated with under-reporting of alcohol consumption by patients who denied alcohol use in clinical and research settings using an alcohol biomarker. We enrolled ART-naïve, HIV-infected adults at Mbarara Hospital HIV clinic in Uganda. We conducted baseline interviews on alcohol use, demographics, Spirituality and Religiosity Index (SRI), health and functional status; and tested for breath alcohol content and collected blood for phosphatidylethanol (PEth), a sensitive and specific biomarker of alcohol use...
February 13, 2017: AIDS Care
https://www.readbyqxmd.com/read/28273350/sexual-dysfunction-and-its-determinants-among-women-infected-with-hiv
#15
Patricia A Agaba, Seema T Meloni, Halima M Sule, Emmanuel I Agaba, John A Idoko, Phyllis J Kanki
OBJECTIVE: To describe the prevalence of female sexual dysfunction (FSD) and its determinants among women with HIV infection enrolled for care and treatment in an ambulatory care setting. METHODS: A questionnaire-based cross-sectional survey was conducted among women attending the HIV clinic of Jos University Teaching Hospital, Nigeria, between March 2013 and February 2014. The self-administered Female Sexual Function Index (FSFI) was used to assess FSD; a score of less than 26...
March 8, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28270536/relationships-between-neighbourhood-characteristics-and-current-sti-status-among-hiv-infected-and-hiv-uninfected-women-living-in-the-southern-usa-a-cross-sectional-multilevel-analysis
#16
Danielle F Haley, Michael R Kramer, Adaora A Adimora, Regine Haardörfer, Gina M Wingood, Christina Ludema, Anna Rubtsova, DeMarc A Hickson, Zev Ross, Elizabeth Golub, Hector Bolivar, Hannah Lf Cooper
OBJECTIVES: Neighbourhood characteristics (eg, high poverty rates) are associated with STIs among HIV-uninfected women in the USA. However, no multilevel analyses investigating the associations between neighbourhood exposures and STIs have explored these relationships among women living with HIV infection. The objectives of this study were to: (1) examine relationships between neighbourhood characteristics and current STI status and (2) investigate whether the magnitudes and directions of these relationships varied by HIV status in a predominantly HIV-infected cohort of women living in the Southern USA...
March 7, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28267790/cigarette-smoking-is-associated-with-high-hiv-viral-load-among-adults-presenting-for-antiretroviral-therapy-in-vietnam
#17
Todd M Pollack, Hao T Duong, Thuy T Pham, Cuong D Do, Donn Colby
High HIV viral load (VL >100,000 cp/ml) is associated with increased HIV transmission risk, faster progression to AIDS, and reduced response to some antiretroviral regimens. To better understand factors associated with high VL, we examined characteristics of patients presenting for treatment in Hanoi, Vietnam. We examined baseline data from the Viral Load Monitoring in Vietnam Study, a randomized controlled trial of routine VL monitoring in a population starting antiretroviral therapy (ART) at a clinic in Hanoi...
2017: PloS One
https://www.readbyqxmd.com/read/28252529/immunodeficiency-aids-related-pneumonia-and-risk-of-lung-cancer-among-hiv-infected-individuals
#18
Julia L Marcus, Wendy A Leyden, Chun R Chao, Michael A Horberg, Daniel B Klein, Charles P Quesenberry, William J Towner, Michael J Silverberg
OBJECTIVE: To clarify the role of immunodeficiency and pneumonia in elevated lung cancer risk among HIV-infected individuals. DESIGN: Cohort study of HIV-infected and HIV-uninfected adults in a large integrated healthcare system in California during 1996-2011. METHODS: We used Poisson models to obtain rate ratios (RR) for lung cancer associated with HIV infection, overall and stratified by recent CD4 cells/μL (HIV-uninfected as reference group), with chi-square tests for trends across CD4 strata...
March 1, 2017: AIDS
https://www.readbyqxmd.com/read/28243934/risky-sex-and-hiv-acquisition-among-hiv-serodiscordant-couples-in-zambia-2002-2012-what-does-alcohol-have-to-do-with-it
#19
Dvora Joseph Davey, William Kilembe, Kristin M Wall, Naw Htee Khu, Ilene Brill, Bellington Vwalika, Elwyn Chomba, Joseph Mulenga, Amanda Tichacek, Marjan Javanbakht, W Scott Comulada, Susan Allen, Pamina M Gorbach
In this paper we evaluate the effects of heavy alcohol consumption on sexual behavior, HIV acquisition, and antiretroviral treatment (ART) initiation in a longitudinal open cohort of 1929 serodiscordant couples in Lusaka, Zambia from 2002 to 2012. We evaluated factors associated with baseline heavy alcohol consumption and its association with condomless sex with the study partner, sex outside of the partnership, and ART initiation using multivariable logistic regression. We estimated the effect of alcohol consumption on HIV acquisition using multivariable Cox models...
February 27, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28235839/sexual-partner-characteristics-and-incident-rectal-neisseria-gonorrhoeae-and-chlamydia-trachomatis-infections-among-gay-men-and-other-men-who-have-sex-with-men-msm-a-prospective-cohort-in-abuja-and-lagos-nigeria
#20
Habib O Ramadhani, Hongjie Liu, Rebecca G Nowak, Trevor A Crowell, Teclaire Ndomb, Charlotte Gaydos, Sheila Peel, Nicaise Ndembi, Stefan D Baral, Julie Ake, Man E Charurat
BACKGROUND: STIs including Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) potentiate HIV acquisition and transmission especially among gay men and other men who have sex with men (MSM). We investigated the influence of sexual network composition on incident rectal NG and/or CT infections among Nigerian MSM. METHODS: TRUST/RV368 is a cohort of MSM recruited using respondent-driven sampling at trusted community centres in Abuja and Lagos, Nigeria. MSM respondents (egos) provided STI risk factors and demographic information for up to five of their most recent sexual partners (alters) within their sexual networks...
February 24, 2017: Sexually Transmitted Infections
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