keyword
MENU ▼
Read by QxMD icon Read
search

Vitamin d3

keyword
https://www.readbyqxmd.com/read/29350749/quality-characteristics-of-a-low-fat-beef-patty-enriched-by-polyunsaturated-fatty-acids-and-vitamin-d3
#1
Inmaculada Gómez, María Victoria Sarriés, Francisco C Ibañez, María José Beriain
Olive and linseed oils have high contents of oleic acid and n-3 fatty acids (FA), respectively. Vitamin D3 , an essential nutrient, is in low contents in meat. This study investigated the potential application of olive and linseed oils' mixture as a backfat replacer, and vitamin D3 as a supplement, in order to develop a product enriched by polyunsaturated FAs and vitamin D3 . Two treatments were manufactured: conventional (C: 0% emulsion, 0 μg vitamin D3 /100 g product) and modified (M: 10.9% emulsion/, 8...
January 19, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29349624/combined-effects-of-aspirin-and-vitamin-d3-on-two-oscc-cell-lines-a-preliminary-study
#2
Ting-Ting Xiao, Xian Li, Jia-Li Feng, Yong Li
OBJECTIVES: We evaluated the potential effects of aspirin combined with vitamin D3 on cell proliferation and apoptosis in oral cancer cells. RESULTS: Compared to the untreated control or individual drug, the combinations of aspirin and vitamin D3 significantly decreased the rates of cell proliferation by CCK-8 assay, and caused higher rates of cell apoptosis in both CAL-27 and SCC-15 cells by Annexin V-FITC apoptosis assay and flow cytometry. Remarkably, the combined treatment with aspirin and vitamin D3 significantly suppressed the expression of Bcl-2 protein and p-Erk1/2 protein, examined by western blot analysis...
January 18, 2018: Biotechnology Letters
https://www.readbyqxmd.com/read/29343609/polymorphic-human-sulfotransferase-2a1-mediates-the-formation-of-25-hydroxyvitamin-d3-3-o-sulfate-a-major-circulating-vitamin-d-metabolite-in-humans
#3
Timothy Wong, Zhican Wang, Brian D Chapron, Mizuki Suzuki, Katrina G Claw, Chunying Gao, Robert S Foti, Bhagwat Prasad, Alenka Chapron, Justina Calamia, Amarjit Chaudhry, Erin G Schuetz, Ronald L Horst, Qingcheng Mao, Ian H de Boer, Timothy A Thornton, Kenneth E Thummel
Metabolism of 25-hydroxyvitamin D3 (25OHD3) plays a central role in regulating the biological effects of vitamin D in the body. Although cytochrome P450-dependent hydroxylation of 25OHD3 has been extensively investigated, limited information is available on the conjugation of 25OHD3. In the present study, we report that 25OHD3 is selectively conjugated to 25OHD3-3-O-sulfate by human sulfotransferase 2A1 (SULT2A1) and that the liver is a primary site of metabolite formation. At a low (50 nM) concentration of 25OHD3, 25OHD3-3-O-sulfate was the most abundant metabolite, with an intrinsic clearance approximately 8-fold higher than the next most efficient metabolic route...
January 17, 2018: Drug Metabolism and Disposition: the Biological Fate of Chemicals
https://www.readbyqxmd.com/read/29342138/%C3%AE-klotho-is-a-non-enzymatic-molecular-scaffold-for-fgf23-hormone-signalling
#4
Gaozhi Chen, Yang Liu, Regina Goetz, Lili Fu, Seetharaman Jayaraman, Ming-Chang Hu, Orson W Moe, Guang Liang, Xiaokun Li, Moosa Mohammadi
The ageing suppressor α-klotho binds to the fibroblast growth factor receptor (FGFR). This commits FGFR to respond to FGF23, a key hormone in the regulation of mineral ion and vitamin D homeostasis. The role and mechanism of this co-receptor are unknown. Here we present the atomic structure of a 1:1:1 ternary complex that consists of the shed extracellular domain of α-klotho, the FGFR1c ligand-binding domain, and FGF23. In this complex, α-klotho simultaneously tethers FGFR1c by its D3 domain and FGF23 by its C-terminal tail, thus implementing FGF23-FGFR1c proximity and conferring stability...
January 17, 2018: Nature
https://www.readbyqxmd.com/read/29340280/serum-vitamin-d-levels-in-treatment-na%C3%A3-ve-chronic-hepatitis-b-patients
#5
Ebada Said, Waleed El Agawy, Rehab Ahmed, Mohamed Hassany, Amal Ahmed, Hanan Fouad, Hosam Baiumy
Background and Objectives: According to the demographic health survey conducted in 2015, Egypt had 10% documented prevalence of anti-HBc positive patients aged 1-59 and 1% viremic patients amongst the population in the same age group, with a domination of genotype D. Several studies claimed the possible role of vitamin D deficiency in hepatitis B virus (HBV) replication and disease progression. Patients and Methods: Serum vitamin D levels [25(OH D3] were assessed in 96 HBeAg negative non-cirrhotic chronic HBV patients and 25 healthy subjects classified as following: Group I: 48 chronic HBV patients with persistently normal ALT levels and HBV DNA level < 2000 IU/mL for ≥ 6 months; Group II: 48 chronic HBV patients with CHB with persistently elevated ALT and HBV DNA level ≥ 2000 IU/mL for ≥ 6 months; and Group III: 25 apparently healthy subjects with normal liver enzymes and negative hepatitis viral markers were taken as the control group...
December 2017: Journal of Translational Internal Medicine
https://www.readbyqxmd.com/read/29336863/age-associated-expression-of-vitamin-d-receptor-and-vitamin-d-metabolizing-enzymes-in-the-male-reproductive-tract-and-sperm-of-hu-sheep
#6
Xiaolei Yao, M A Ei-Samahy, Hua Yang, Xu Feng, Fengzhe Li, Fanxing Meng, Haitao Nie, Feng Wang
The cellular response to 1,25-dihydroxyvitamin D3 (Vit D3; biologically active form of Vitamin D) is complex and depends not only on Vitamin D receptor (VDR) expression but also on cellular uptake of circulating Vit D3 and the presence and activity of Vitamin D-metabolizing enzyme. This study evaluated the expression of VDR and Vitamin D-metabolizing enzymes in the ram reproductive tract at different developmental stages and in spermatozoa. Nearly all cell types in the testes and epithelial cells of the caput, corpus, and cauda expressed VDR, CYP27B1, and CYP24A1 proteins...
January 10, 2018: Animal Reproduction Science
https://www.readbyqxmd.com/read/29336628/effect-of-multi-ingredient-supplement-containing-satiereal-naringin-and-vitamin-d-on-body-composition-mood-and-satiety-in-overweight-adults
#7
Adam M Gonzalez, Katie M Sell, Jamie J Ghigiarelli, Robert W Spitz, Matthew R Accetta, Gerald T Mangine
The purpose of this investigation was to examine the effects of 28 days of a dietary supplement on body composition, mood, and satiety in overweight adults. Twenty healthy adults (25.5 ± 3.8 years; 87.3 ± 20.7 kg; 169.9 ± 10.6 cm; 29.9 ± 5.1 body mass index) participated in this randomized, double-blind, placebo-controlled investigation. Ten participants were provided with a dietary supplement containing 178 mg satiereal, 100 mg naringin, and 2,000 IU vitamin D3 daily (SUPP), and ten participants were provided a placebo (PL) for 28 days...
January 16, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29335688/multiple-invasive-cervical-resorption-and-celiac-disease-a-case-report
#8
Katarzyna Dobroś, Paweł Myciński, Przemysław Borowy, Joanna Zarzecka
Multiple invasive cervical resorption (MICR) is a rare disease of unknown etiology. A case of a patient with MICR of six teeth, with low vitamin D3 level detected, is presented. Applied surgical and general treatments were only partially effective, as they failed to stop the resorption, although the parameters of calcium-phosphate management appreciably improved, and secondary hyperparathyroidism was successfully resolved.
January 15, 2018: Quintessence International
https://www.readbyqxmd.com/read/29334624/adequate-vitamin-d3-skin-synthesis-versus-erythema-risk-in-the-northern-hemisphere-midlatitudes
#9
Jakub Guzikowski, Janusz Krzyścin, Agnieszka Czerwińska, Weronika Raszewska
Health-optimum-exposure index (HOEI) is proposed to assess if the prescribed amount of vitamin D3 (target value) could be synthesized in the human skin without erythema appearance. It is defined as the ratio between the vitamin D3 quantity received during the maximum allowed outdoor exposure without erythema risk and the target value. Sunbathing is safe for HOEI>1 and 1/HOEI represents a part of minimal erythema dose (MED) necessary to obtain the target value. We examine the following targets: a vitamin D3 quantity equivalent to 1000 IU vitamin D3 taken orally, and an optimal vitamin D3 quantity defined by Krzyścin et al...
January 11, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29331461/stabilizing-vitamin-d3-using-the-molten-globule-state-of-%C3%AE-lactalbumin
#10
Jannik Nedergaard Pedersen, Henrik V Sørensen, Daniel E Otzen
α-Lactalbumin (α-LA) is the second most abundant bovine whey protein. It has been intensively studied because of its readiness to populate the molten globular (MG) state, a partially folded state with native levels of secondary structure but loss of tertiary structure. The MG state of α-LA exposes a significant number of hydrophobic patches that could be used to bind and stabilize small hydrophobic molecules such as vitamin D3 (vitD). Accordingly, we tested the ability of α-LA to stabilize vitD in a pH interval from 7...
January 10, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29330997/comparison-of-different-formulations-of-vitamin-d
#11
Hafiz Muhammad Fahan Rashid, Uneeba Syed, Zaheer Ahmad, Kbaa Khalil Chauhdary, Usman Musharraf, Suresh Kumar
BACKGROUND: Vitamin D Deficiency (VDD) is responsible for a wide spectrum of clinical diseases and vitamin D deficiency prevalence is frightening in most parts of the world including Pakistan. Therefore, supplementations of vitamin D are used in the population at high risk for the prevention and the treatment of vitamin D deficiency. Vitamin D supplementation comes in various formulations both oral and intramuscular. Cholecalciferol is the most commonly used preparation which is given through these routes of administration...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29326421/vitamin-d3-fortified-milk-did-not-affect-glycemic-control-lipid-profile-and-anthropometric-measures-in-patients-with-type-2-diabetes-a-triple-blind-randomized-clinical-trial
#12
Saedeh Salehi, Fatemeh Sadeghi, Masoumeh Akhlaghi, Mohammad Amin Hanifpour, Mahdi Roshanzamir
BACKGROUND/OBJECTIVES: The effect of vitamin D on glycemic status of diabetes patients is controversial. The objective was to assess the effect of vitamin D3-fortified milk on cardiometabolic markers of patients with type 2 diabetes. SUBJECTS/METHODS: In this randomized triple-blind, placebo-controlled trial, 102 patients (34 males and 68 females) aged 31-74 years with type 2 diabetes were randomized to receive either 250 ml unfortified or 250 ml 1000 IU vitamin D3-fortified milk daily for 9 weeks...
January 11, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29325695/investigation-of-the-uterine-structural-changes-in-the-experimental-model-with-polycystic-ovary-syndrome-and-effects-of-vitamin-d-treatment-an-ultrastructural-and-immunohistochemical-study
#13
Yurdun Kuyucu, Latife Seyran Çelik, Özge Kendirlinan, Özgül Tap, Ufuk Özgü Mete
In this study, we aimed to investigate the structural changes seen in the endometrium in experimental PCOS rat model and the effects of vitamin D treatment on these changes at immunohistochemical and electron microscopic levels. 24 prepubertal female rats were divided into three groups. Two groups were injected with dehydroepiandrosterone and one of them was treated with 1,25(OH)2 D3 at the same time. The control group was injected with sesame oil. At the end of the 28th day, the blood samples were collected...
January 8, 2018: Reproductive Biology
https://www.readbyqxmd.com/read/29325125/age-phosphorus-and-25-hydroxycholecalciferol-regulate-mrna-expression-of-vitamin-d-receptor-and-sodium-phosphate-cotransporter-in-the-small-intestine-of-broiler-chickens
#14
J C Han, J L Zhang, N Zhang, X Yang, H X Qu, Y Guo, C X Shi, Y F Yan
Four experiments were conducted in this study. Experiment 1 was carried out to examine mRNA expressions of nuclear vitamin D receptor (nVDR), membrane vitamin D receptor (mVDR), and type IIb sodium-phosphate cotransporter (NaPi-IIb) in the small intestine of broiler chickens. Experiments 2, 3, and 4 were implemented to evaluate effects of age, non-phytate phosphorus (NPP), and 25-hydroxycholecalciferol (25-OH-D3) on mRNA expressions of nVDR, mVDR, and NaPi-IIb in the duodenum of chickens. Results showed that mRNA expression levels of nVDR and NaPi-IIb were highest in the duodenum of 21-day-old broilers, lower in the jejunum, and lowest in the ileum...
January 6, 2018: Poultry Science
https://www.readbyqxmd.com/read/29325121/plasma-25-hydroxyvitamin-d-and-mortality-in-patients-with-suspected-stable-angina-pectoris
#15
Eirik Degerud, Ottar Nygård, Stefan de Vogel, Rune Hoff, Gard Frodahl Tveitevåg Svingen, Eva Ringdal Pedersen, Dennis Winston Trygve Nilsen, Jan Erik Nordrehaug, Øivind Midttun, Per Magne Ueland, Jutta Dierkes
Context and objective: Vitamin D status may affect cardiovascular disease (CVD) development and survival. We studied the relationship between concentrations of the circulating biomarker 25-hydroxyvitamin D (25OHD) and all-cause and cardiovascular mortality risk. Design, Setting, Participants and main Outcome Measures: 25OHD, the sum of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2, was analysed in plasma samples from 4114 Caucasian patients with suspected stable angina pectoris, and adjusted for seasonal variation...
January 9, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29317287/in-vivo-response-of-the-human-epigenome-to-vitamin-d-a-proof-of-principle-study
#16
Carsten Carlberg, Sabine Seuter, Tarja Nurmi, Tomi-Pekka Tuomainen, Jyrki K Virtanen, Antonio Neme
In vitro cell culture studies showed that the hormonal form of vitamin D3, 1α,25-dihydroxyvitamin D3, significantly (p < 0.05) affects the human epigenome at thousands of genomic loci. Phase II of the VitDbol vitamin D intervention trial (NCT02063334) involved a proof-of-principle study of one individual, who was exposed three times every 28 days to an oral bolus (2,000 µg) of vitamin D3. Blood samples were taken directly before each supplementation as well as one and two days after, chromatin was isolated from peripheral blood mononuclear cells without any further in vitro culture and at all nine time points epigenome-wide chromatin accessibility was assessed by applying FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing)...
January 6, 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29316495/vdr-and-gc-gene-polymorphisms-modulate-the-risk-of-lumbar-disc-degeneration-in-iran
#17
Sohail Mashayekhi, Alia Saberi, Zivar Salehi, Gelareh Biazar, Roghayeh Mehrdel
OBJECTIVE: Lumbar disc degeneration (LDD) occurs commonly in humans. Vitamin D metabolic and signaling pathway plays a significant role in intervertebral disc degeneration. The aim of this study was to evaluate the influence of the genetic polymorphism in the two key genes of 1,25-(OH)2-D3 pathway, VDR (vitamin D receptor) and GC (group-specific component), in LDD development. PATIENTS AND METHODS: Two single-nucleotide polymorphisms, VDR rs2228570 (FokI) and GC rs7041, were genotyped in 180 patients with LDD and 230 healthy individuals...
December 29, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29316289/flotation-ultrasound-assisted-microextraction-followed-by-hplc-for-the-determination-of-fat-soluble-vitamins-in-multivitamin-pharmaceutical-preparations
#18
Parvin Shahdousti, Mohammad Aghamohammadi
Dissolved carbon dioxide flotation-emulsification microextraction technique coupled with high-performance liquid chromatography was developed for the separation and determination of fat-soluble vitamins (A, D3 , E and K3 ) in multivitamin pharmaceutical preparations. Dissolved carbon dioxide flotation was used to break up the emulsion of extraction solvent in water and to collect the extraction solvent on the surface of the aqueous sample in the narrowed capillary part of extraction cell. Carbon dioxide bubbles were generated in situ through the addition of 300 μL of concentrated hydrochloric acid into the alkaline sample solution at pH = 11...
January 5, 2018: Journal of Separation Science
https://www.readbyqxmd.com/read/29310423/phloxine-o-a-cosmetic-colorant-suppresses-the-expression-of-thymic-stromal-lymphopoietin-and-acute-dermatitis-symptoms-in-mice
#19
Hye Eun Lee, Gabsik Yang, Kyu-Bong Kim, Byung-Mu Lee, Joo Young Lee
Cosmetics are primarily applied to the skin; therefore, the association of cosmetic dyes with skin diseases or inflammation is a topic of great interest. Thymic stromal lymphopoietin (TSLP) is an interleukin 7-like cytokine that activates dendritic cells to promote Th2 inflammatory immune responses. TSLP is highly expressed in keratinocytes under inflammatory conditions, which suggests that it may play a critical role in the development of skin diseases, such as atopic dermatitis. Therefore, we investigated whether cosmetic dyes influenced the production of TSLP by keratinocytes...
January 9, 2018: Biomolecules & Therapeutics
https://www.readbyqxmd.com/read/29306481/effect-of-calcifediol-treatment-on-cardiovascular-outcomes-in-patients-with-acute-coronary-syndrome-and-percutaneous-revascularization
#20
Cristina Navarro-Valverde, Jose M Quesada-Gómez, Ramón Pérez-Cano, Ana Fernández-Palacín, Luis F Pastor-Torres
BACKGROUND AND OBJECTIVES: Vitamin D deficiency has been consistently linked with cardiovascular diseases. However, results of intervention studies are contradictory. The aim of this study was to evaluate the effect of treatment with calcifediol (25(OH)D3) on the cardiovascular system of patients with non-ST-elevation acute coronary syndrome after percutaneous coronary intervention. PATIENTS AND METHODS: A prospective study assessing≥60-year-old patients with non-ST-elevation acute coronary syndrome, coronary artery disease and percutaneous revascularisation...
January 3, 2018: Medicina Clínica
keyword
keyword
67285
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"