keyword
MENU ▼
Read by QxMD icon Read
search

Developmental coordination disorder

keyword
https://www.readbyqxmd.com/read/29749079/acute-tau-knockdown-in-the-hippocampus-of-adult-mice-causes-learning-and-memory-deficits
#1
Ramon Velazquez, Eric Ferreira, An Tran, Emily C Turner, Ramona Belfiore, Caterina Branca, Salvatore Oddo
Misfolded and hyperphosphorylated tau accumulates in several neurodegenerative disorders including Alzheimer's disease, frontotemporal dementia with Parkinsonism, corticobasal degeneration, progressive supranuclear palsy, Down syndrome, and Pick's disease. Tau is a microtubule-binding protein, and its role in microtubule stabilization is well defined. In contrast, while growing evidence suggests that tau is also involved in synaptic physiology, a complete assessment of tau function in the adult brain has been hampered by robust developmental compensation of other microtubule-binding proteins in tau knockout mice...
May 10, 2018: Aging Cell
https://www.readbyqxmd.com/read/29746896/insights-into-cerebellar-development-and-connectivity
#2
REVIEW
Jaclyn Beckinghausen, Roy V Sillitoe
The cerebellum has a well-established role in controlling motor functions such coordination, balance, posture, and skilled learning. There is mounting evidence that it might also play a critical role in non-motor functions such as cognition and emotion. It is therefore not surprising that cerebellar deficits are associated with a wide array of diseases including ataxia, dystonia tremor, schizophrenia, dyslexia, and autism spectrum disorder. What is intriguing is that a seemingly uniform circuit that is often described as being "simple" should carry out all of these behaviors...
May 7, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29741273/is-auditory-perceptual-timing-a-core-deficit-of-developmental-coordination-disorder
#3
Laurel J Trainor, Andrew Chang, John Cairney, Yao-Chuen Li
Time is an essential dimension for perceiving and processing auditory events, and for planning and producing motor behaviors. Developmental coordination disorder (DCD) is a neurodevelopmental disorder affecting 5-6% of children that is characterized by deficits in motor skills. Studies show that children with DCD have motor timing and sensorimotor timing deficits. We suggest that auditory perceptual timing deficits may also be core characteristics of DCD. This idea is consistent with evidence from several domains, (1) motor-related brain regions are often involved in auditory timing process; (2) DCD has high comorbidity with dyslexia and attention deficit hyperactivity, which are known to be associated with auditory timing deficits; (3) a few studies report deficits in auditory-motor timing among children with DCD; and (4) our preliminary behavioral and neuroimaging results show that children with DCD at age 6 and 7 have deficits in auditory time discrimination compared to typically developing children...
May 9, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29727010/quality-of-life-and-psychosocial-functioning-in-adolescents-with-developmental-coordination-disorder-and-attention-deficit-hyperactivity-disorder
#4
John Cairney
No abstract text is available yet for this article.
May 4, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29723752/prenatal-lead-cadmium-and-mercury-exposure-and-associations-with-motor-skills-at-age-7-years-in-a-uk-observational-birth-cohort
#5
Caroline M Taylor, Alan M Emond, Raghu Lingam, Jean Golding
BACKGROUND: Lead and mercury are freely transferred across the placenta, while cadmium tends to accumulate in the placenta. Each contributes to adverse neurological outcomes for the child. Although prenatal heavy metal exposure has been linked with an array of neurodevelopmental outcomes in childhood, its association with the development of motor skills in children has not been robustly studied. AIMS/OBJECTIVE: The aim of the present study was to investigate the association between prenatal exposure to lead, cadmium and mercury, measured as maternal blood concentrations during pregnancy, and motor skills, measured as subtests of the Movement Assessment Battery for Children (Movement ABC) at age 7 years in a large sample of mother-child pairs enrolled in a UK observational birth cohort study (Avon Longitudinal Study of Parents and Children, ALSPAC)...
April 30, 2018: Environment International
https://www.readbyqxmd.com/read/29722020/atrioventricular-canal-defect-and-genetic-syndromes-the-unifying-role-of-sonic-hedgehog
#6
REVIEW
M C Digilio, F Pugnaloni, A De Luca, G Calcagni, A Baban, M L Dentici, P Versacci, B Dallapiccola, M Tartaglia, B Marino
The atrioventricular canal defect (AVCD) is a congenital heart defect (CHD) frequently associated with extracardiac anomalies (75%). Previous observations from a personal series of patients with AVCD and "polydactyly syndromes" demonstrated that the distinct morphology and combination of AVCD features in some of these syndromes is reminiscent of the cardiac phenotype found in heterotaxy, a malformation complex previously associated with functional cilia abnormalities and aberrant Hedgehog (Hh) signaling...
May 3, 2018: Clinical Genetics
https://www.readbyqxmd.com/read/29699866/effects-of-practice-on-visual-finger-force-control-in-children-at-risk-of-developmental-coordination-disorder
#7
Maria Angélica da Rocha Diz, Marcela de Castro Ferracioli, Cynthia Yukiko Hiraga, Marcio Alves de Oliveira, Ana Maria Pellegrini
BACKGROUND: The production of finger force control is essential for a large number of daily activities. There is evidence that deficits in the mechanisms of accuracy and control of finger force tasks are associated with children's motor difficulties. OBJECTIVE: To compare the effect of practice of an isometric finger force/torque task between children with significant movement difficulty and those with no difficulty movement. METHODS: Twenty-four children aged between 9 and 10 years (12 at risk of developmental coordination disorder and 12 with no movement difficulty - typically developing children) were asked to produce finger force/torque control in a continuous and constant 25% of maximum voluntary torque with visual feedback during 15s...
April 14, 2018: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/29691944/developmental-performance-of-5-year-old-bulgarian-children-an-example-of-translational-neuroscience-in-practice
#8
Ralitsa Yordanova, Ivan Ivanov
RATIONALE, AIMS, AND OBJECTIVES: Developmental testing is essential for early recognition of the various developmental impairments. The tools used should be composed of items that are age specific, adapted, and standardized for the population they are applied to. The achievements of neurosciences, medicine, psychology, pedagogy, etc. are applied in the elaboration of a comprehensive examination tool that should screen all major areas of development. The key age of 5 years permits identification of almost all major developmental disabilities leaving time for therapeutic intervention before school entrance...
April 25, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29672338/effects-of-a-care-coordination-intervention-with-children-with-neurodevelopmental-disabilities-and-their-families
#9
Jeanne W McAllister, Rebecca McNally Keehn, Rylin Rodgers, Philani Brian Mpofu, Patrick O Monahan, Thomas M Lock
: Care coordination is integral to improving the health of children and families. Using a Shared Plan of Care (SPoC) as a care coordination activity is recommended, but related research on outcomes in pediatric populations with complex medical conditions is scarce. OBJECTIVE: This study explores family outcomes associated with implementation of a care coordination/SPoC intervention with a population of children with neurodevelopmental disabilities and their families. METHODS: Children aged 2 to 10 years with a neurodevelopmental disability (autism spectrum disorder: 60...
April 17, 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29671621/a-research-framework-to-isolate-visuospatial-from-childhood-motor-coordination-phenotypes
#10
Michele Poletti
Clinicians acknowledge the presence of developmental cognitive phenotypes mainly characterized by a specific visuospatial impairment in presence of intact verbal functioning (usually referred as Nonverbal Learning Disability: NLD) since many decades, without providing sufficient empirical evidence supporting their nosological validity and inclusion in current diagnostic manuals. This contribution suggests that the goal of including NLD in future diagnostic manuals could be achieved only be the demonstration of the validity of this hypothesized clinical category...
April 19, 2018: Applied Neuropsychology. Child
https://www.readbyqxmd.com/read/29656792/training-children-aged-5-10-years-in-manual-compliance-control-to-improve-drawing-and-handwriting
#11
Geoffrey P Bingham, Winona Snapp-Childs
A large proportion of school-aged children exhibit poor drawing and handwriting. This prevalence limits the availability of therapy. We developed an automated method for training improved manual compliance control and relatedly, prospective control of a stylus. The approach included a difficult training task, while providing parametrically modifiable support that enables the children to perform successfully while developing good compliance control. The task was to use a stylus to push a bead along a 3D wire path...
April 12, 2018: Human Movement Science
https://www.readbyqxmd.com/read/29628909/interhemispheric-cortical-inhibition-is-reduced-in-young-adults-with-developmental-coordination-disorder
#12
Jason L He, Ian Fuelscher, Peter G Enticott, Wei-Peng Teo, Pamela Barhoun, Christian Hyde
Introduction: While the etiology of developmental coordination disorder (DCD) is yet to be established, brain-behavior modeling provides a cogent argument that neuropathology may subserve the motor difficulties typical of DCD. We argue that a number of the core behavioral features of the DCD profile (such as poor surround inhibition, compromised motor inhibition, and the presence of mirror movements) are consistent with difficulties regulating inhibition within the primary motor cortex (M1)...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29623050/linear-and-nonlinear-analyses-of-the-cardiac-autonomic-control-in-children-with-developmental-coordination-disorder-a-case-control-study
#13
Jorge L Cavalcante Neto, Antonio R Zamunér, Bianca C Moreno, Ester Silva, Eloisa Tudella
Children with Developmental Coordination Disorder (DCD) and children at risk for DCD (r-DCD) present motor impairments interfering in their school, leisure and daily activities. In addition, these children may have abnormalities in their cardiac autonomic control, which together with their motor impairments, restrict their health and functionality. Therefore, this study aimed to assess the cardiac autonomic control, by linear and nonlinear analysis, at supine and during an orthostatic stimulus in DCD, r-DCD and typically developed children...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29611868/health-related-quality-of-life-and-peer-relationships-in-adolescents-with-developmental-coordination-disorder-and-attention-deficit-hyperactivity-disorder
#14
Deborah Dewey, Anna Volkovinskaia
AIM: Health-related quality of life (HRQoL) and peer relationships were investigated in adolescents with developmental coordination disorder (DCD) and attention-deficit-hyperactivity disorder (ADHD). METHOD: Adolescents with DCD (n=9), ADHD (n=9), DCD and ADHD (n=10), and typically developing adolescents (n=16) completed the following questionnaires: KIDSCREEN-52 Health-Related Quality of Life Questionnaire and Peer Relations Questionnaire for Children. Twenty-five participants took part in semi-structured interviews...
April 3, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29605507/developmental-dysgraphia-is-often-associated-with-minor-neurological-dysfunction-in-children-with-developmental-coordination-disorder-dcd
#15
Clémence Lopez, Cherhazad Hemimou, Bernard Golse, Laurence Vaivre-Douret
OBJECTIVES: Children with developmental coordination disorder (DCD) are particularly affected by handwriting disorders, which remain poorly understood and are not clearly defined. The aim of our study is to provide a better understanding of handwriting disorders, and specifically of dysgraphia in children with DCD. METHODS: Sixty-five children with DCD (5-15 years), enrolled according to DSM-5, were assessed with handwriting testing and standardized assessments of neuropsychological, neurovisual, MRI and neuropsychomotor functions, with special attention paid to muscular tone examination...
March 28, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/29593783/perinatal-programming-of-circadian-clock-stress-crosstalk
#16
REVIEW
Mariana Astiz, Henrik Oster
An intact communication between circadian clocks and the stress system is important for maintaining physiological homeostasis under resting conditions and in response to external stimuli. There is accumulating evidence for a reciprocal interaction between both-from the systemic to the molecular level. Disruption of this interaction by external factors such as shiftwork, jetlag, or chronic stress increases the risk of developing metabolic, immune, or mood disorders. From experiments in rodents, we know that both systems maturate during the perinatal period...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29588389/grain-size-and-number1-negatively-regulates-the-osmkkk10-osmkk4-osmpk6-cascade-to-coordinate-the-trade-off-between-grain-number-per-panicle-and-grain-size-in-rice
#17
Tao Guo, Ke Chen, Nai-Qian Dong, Chuan-Lin Shi, Wang-Wei Ye, Ji-Ping Gao, Jun-Xiang Shan, Hong-Xuan Lin
Grain number and size are interactive agronomic traits that determine grain yield. However, the molecular mechanisms responsible for coordinating the trade-off between these traits remain elusive. Here, we characterized the rice (Oryza sativa) grain size and number 1 (gsn1) mutant, which has larger grains but sparser panicles than the wild type due to disordered localized cell differentiation and proliferation. GSN1 encodes the mitogen-activated protein kinase phosphatase OsMKP1, a dual-specificity phosphatase of unknown function...
March 27, 2018: Plant Cell
https://www.readbyqxmd.com/read/29578997/commentary-on-role-of-pediatric-physical-therapists-in-promoting-sports-participation-in-developmental-coordination-disorder
#18
Lisa Dannemiller, Melinda Mueller
No abstract text is available yet for this article.
April 2018: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/29578996/role-of-pediatric-physical-therapists-in-promoting-sports-participation-in-developmental-coordination-disorder
#19
Imke L J Adams, Wenke Broekkamp, Peter H Wilson, Christine Imms, Anneloes Overvelde, Bert Steenbergen
PURPOSE: To explore the role of pediatric physical therapists (PPT) in promoting sports participation in children with developmental coordination disorder (DCD) and identify associated barriers and facilitators. METHODS: Questionnaires were provided to 243 PPTs. Qualitative, semistructured, in-depth interviews were administered with the PPTs, children with DCD, and parents. RESULTS: Approximately 67% of questionnaires were returned. Approximately 46% of PPTs were active in guiding children with DCD to sports clubs...
April 2018: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/29569748/maternal-obesity-alters-uterine-nk-activity-through-a-functional-kir2dl1-s1-imbalance
#20
Barbara Castellana, Sofie Perdu, Yoona Kim, Kathy Chan, Jawairia Atif, Megan Marziali, Alexander G Beristain
In pregnancy, uterine natural killer cells (uNK) play essential roles in coordinating uterine angiogenesis, blood vessel remodeling, and promoting maternal tolerance to fetal tissue. Deviances from a normal uterine microenvironment are thought to modify uNK function(s) by limiting their ability to establish a healthy pregnancy. While maternal obesity has become a major health concern due to associations with adverse effects on fetal and maternal health, our understanding into how obesity contributes to poor pregnancy disorders is unknown...
March 23, 2018: Immunology and Cell Biology
keyword
keyword
67283
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"