keyword
MENU ▼
Read by QxMD icon Read
search

Developmental coordination disorder

keyword
https://www.readbyqxmd.com/read/28650077/considerations-on-the-assessment-of-developmental-coordination-disorder-and-the-elaboration-of-related-contextual-pathways
#1
Matthias Wagner
No abstract text is available yet for this article.
June 26, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28645799/genotype-phenotype-evaluation-of-med13l-defects-in-the-light-of-a-novel-truncating-and-a-recurrent-missense-mutation
#2
Reza Asadollahi, Markus Zweier, Laura Gogoll, Raphael Schiffmann, Heinrich Sticht, Katharina Steindl, Anita Rauch
A decade after the designation of MED13L as a gene and its link to intellectual disability (ID) and dextro-looped transposition of great arteries in 2003, we previously described a recognizable syndrome due to MED13L haploinsufficiency. Subsequent reports of 22 further patients diagnosed by genome-wide testing further delineated the syndrome with expansion of the phenotypic spectrum and showed reduced penetrance for congenital heart defects. We now report two novel patients identified by whole exome sequencing, one with a de novo MED13L truncating mutation and the other with a de novo missense mutation...
June 20, 2017: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/28643166/structural-disorder-in-plant-proteins-where-plasticity-meets-sessility
#3
REVIEW
Alejandra A Covarrubias, Cesar L Cuevas-Velazquez, Paulette S Romero-Pérez, David F Rendón-Luna, Caspar C C Chater
Plants are sessile organisms. This intriguing nature provokes the question of how they survive despite the continual perturbations caused by their constantly changing environment. The large amount of knowledge accumulated to date demonstrates the fascinating dynamic and plastic mechanisms, which underpin the diverse strategies selected in plants in response to the fluctuating environment. This phenotypic plasticity requires an efficient integration of external cues to their growth and developmental programs that can only be achieved through the dynamic and interactive coordination of various signaling networks...
June 22, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28625683/a-developmental-and-clinical-perspective-of-rhythmic-interpersonal-coordination-from-mimicry-toward-the-interconnection-of-minds
#4
Jean Xavier, Julien Magnat, Alain Sherman, Soizic Gauthier, David Cohen, Laurence Chaby
Imitation plays a critical role in the development of intersubjectivity and serves as a prerequisite for understanding the emotions and intentions of others. In our review, we consider spontaneous motor imitation between children and their peers as a developmental process involving repetition and perspective-taking as well as flexibility and reciprocity. During childhood, this playful dynamic challenges developing visuospatial abilities and requires temporal coordination between partners. As such, we address synchrony as form of communication and social signal per se, that leads, from an experience of similarity, to the interconnexion of minds...
June 15, 2017: Journal of Physiology, Paris
https://www.readbyqxmd.com/read/28621420/the-retinal-pigmented-epithelium-from-basic-developmental-biology-research-to-translational-approaches
#5
Benjamin Amram, Yamit Cohen-Tayar, Ahuvit David, Ruth Ashery-Padan
The development of the eye has been a topic of extensive investigation, from the early studies on tissue induction to more recent breakthroughs in resolving the mechanism regulating progenitor patterning and their gradual and coordinated differentiation into diverse tissue types that function together throughout life. Among the ocular tissue types, the retinal pigmented epithelium (RPE) is at the forefront of developmental biology and stem cell research. The growing interest in this lineage stems from its importance for photoreceptor function as well as from its requirement during embryogenesis for the development of the photoreceptors and the choroid...
2017: International Journal of Developmental Biology
https://www.readbyqxmd.com/read/28607477/gabaa-receptor-subunit-gene-polymorphisms-predict-symptom-based-and-developmental-deficits-in-chinese-han-children-and-adolescents-with-autistic-spectrum-disorders
#6
Shuhan Yang, Xuan Guo, Xiaopeng Dong, Yu Han, Lei Gao, Yuanyuan Su, Wei Dai, Xin Zhang
GABAA receptor subunit genes GABRB3, GABRA5, and GABRG3 located on chromosome 15q11-q13 have been implicated in the etiology of autistic spectrum disorders (ASD). This study intended to investigate the possible role of single-nucleotide polymorphisms (SNPs) present in GABRB3 (rs2081648 and rs1426217), GABRA5 (rs35586628), and GABRG3 (rs208129) genes in ASD susceptibility and symptom-based and developmental phenotypes of ASD in Chinese Han children and adolescents. 99 ASD patients and 231 age- and gender- frequency-matched typical developing (TD) controls were tested by TaqMan® genotyping assay...
June 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28575651/mutations-in-nkx6-2-cause-progressive-spastic-ataxia-and-hypomyelination
#7
Viorica Chelban, Nisha Patel, Jana Vandrovcova, M Natalia Zanetti, David S Lynch, Mina Ryten, Juan A Botía, Oscar Bello, Eloise Tribollet, Stephanie Efthymiou, Indran Davagnanam, Fahad A Bashiri, Nicholas W Wood, James E Rothman, Fowzan S Alkuraya, Henry Houlden
Progressive limb spasticity and cerebellar ataxia are frequently found together in clinical practice and form a heterogeneous group of degenerative disorders that are classified either as pure spastic ataxia or as complex spastic ataxia with additional neurological signs. Inheritance is either autosomal dominant or autosomal recessive. Hypomyelinating features on MRI are sometimes seen with spastic ataxia, but this is usually mild in adults and severe and life limiting in children. We report seven individuals with an early-onset spastic-ataxia phenotype...
June 1, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/28565766/a-recurrent-mutation-in-bone-morphogenetic-proteins-2-inducible-kinase-gene-is-associated-with-developmental-dysplasia-of-the-hip
#8
Lihua Zhao, Zaiwei Zhou, Sun Wang, Qing Jiao, Jing Wu, Feng Ma, Lingyan Fan, Mengjie Chen, Hao Ying
Developmental dysplasia of the hip (DDH) is a complex disorder of the hip joint affecting 1-5‰ of newborns. While genetic influence on DDH has been long known, DDH has not been ascribed to any specific genetic event. The present study reported on variants contributing to DDH susceptibility in a family with four individuals affected across three generations. Whole-exome sequencing was performed in three affected and two unaffected individuals of a pedigree with DDH. Candidate variants were confirmed by Sanger sequencing and then validated in available family members and 37 sporadic DDH patients...
May 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28558620/children-with-developmental-coordination-disorder
#9
J M Loftesnes, R P Ingvaldsen, Hermundur Sigmundsson
This study tested the effect of task-specific training of a perceptual ability for children with Developmental Coordination Disorder (DCD) compared to control children. A manual matching task (target location and pointing task) was used, which required the children to locate target pins either visually (seen target) or proprioceptively (felt target), while matching to the located target was always carried out without vision. Thirty-one children (11-12 years) were selected based on teacher statements regarding everyday motor skill performance, the DSM-IV criteria, and the Movement ABC test...
April 2017: Psychological Reports
https://www.readbyqxmd.com/read/28554310/ion-channel-and-neurotransmitter-modulators-as-electroceutical-approaches-to-the-control-of-cancer
#10
Jack Tuszynski, Tatiana M Tilli, Michael Levin
The activities of individual cells must be tightly coordinated in order to build and maintain complex 3-dimensional body structures during embryogenesis and regeneration. Thus, one way to view cancer is within systems biology as a network disorder affecting the ability of cells to properly interact with a morphodynamic field of instructive signals that keeps proliferation and migration orchestrated toward the anatomical needs of the host organism. One layer of this set of instructive microenvironmental cues is bioelectrical...
May 29, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28542867/use-of-active-video-gaming-in-children-with-neuromotor-dysfunction-a-systematic-review
#11
REVIEW
Robbin Hickman, Lisa Popescu, Robert Manzanares, Brendan Morris, Szu-Ping Lee, Janet S Dufek
AIM: To examine current evidence on use of active video gaming (AVG) to improve motor function in children with movement disorders including cerebral palsy, developmental coordination disorder, and Down syndrome. METHOD: Scopus, MEDLINE, Cochrane Library, EMBASE, and CINAHL were searched. Included papers studied the use of AVG for improving movement-related outcomes in these populations. Parameters studied included health condition, strength of evidence, AVG delivery methods, capacity for individualizing play, outcomes addressed, effectiveness for achieving outcomes, and challenges/limitations...
May 19, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28533023/the-rna-modification-n-6-methyladenosine-and-its-implications-in-human-disease
#12
REVIEW
Pedro J Batista
Impaired gene regulation lies at the heart of many disorders, including developmental diseases and cancer. Furthermore, the molecular pathways that control gene expression are often the target of cellular parasites, such as viruses. Gene expression is controlled through multiple mechanisms that are coordinated to ensure the proper and timely expression of each gene. Many of these mechanisms target the life cycle of the RNA molecule, from transcription to translation. Recently, another layer of regulation at the RNA level involving RNA modifications has gained renewed interest of the scientific community...
May 19, 2017: Genomics, Proteomics & Bioinformatics
https://www.readbyqxmd.com/read/28512766/mental-health-outcomes-of-developmental-coordination-disorder-in-late-adolescence
#13
Ian Harrowell, Linda Hollén, Raghu Lingam, Alan Emond
AIM: To assess the relationship between developmental coordination disorder (DCD) and mental health outcomes in late adolescence. METHOD: Data were analyzed from the Avon Longitudinal Study of Parents and Children. Moderate-to-severe DCD was defined at 7 to 8 years according to the DSM-IV-TR criteria. Mental health was assessed at 16 to 18 years using self-reported questionnaires: Strengths and Difficulties Questionnaire, Short Moods and Feelings Questionnaire, and the Warwick-Edinburgh Mental Well-being Scale...
May 16, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28484035/intersectin-1-is-a-component-of-the-reelin-pathway-to-regulate-neuronal-migration-and-synaptic-plasticity-in-the-hippocampus
#14
Burkhard Jakob, Gaga Kochlamazashvili, Maria Jäpel, Aziz Gauhar, Hans H Bock, Tanja Maritzen, Volker Haucke
Brain development and function depend on the directed and coordinated migration of neurons from proliferative zones to their final position. The secreted glycoprotein Reelin is an important factor directing neuronal migration. Loss of Reelin function results in the severe developmental disorder lissencephaly and is associated with neurological diseases in humans. Reelin signals via the lipoprotein receptors very low density lipoprotein receptor (VLDLR) and apolipoprotein E receptor 2 (ApoER2), but the exact mechanism by which these receptors control cellular function is poorly understood...
May 23, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28481145/lack-of-motor-inhibition-as-a-marker-of-learning-difficulties-of-bimanual-coordination-in-teenagers-with-developmental-coordination-disorder
#15
Mélody Blais, Charlène Baly, Maëlle Biotteau, Jean-Michel Albaret, Yves Chaix, Jessica Tallet
This study tested the learning of a new bimanual coordination in teenagers with and without Developmental Coordination Disorder (DCD). Both groups improved accuracy of the new coordination. No difference was found on stability. But DCD teenagers exhibited an overall higher number of additional taps, suggesting a persistent lack of motor inhibition during learning. Moreover, teenagers with the lowest scores of motor abilities present the highest number of additional taps. All these results suggest that this number of additional taps (rather than traditional measures of accuracy and stability) could be a good marker of perceptual-motor learning deficit in DCD...
May 8, 2017: Developmental Neuropsychology
https://www.readbyqxmd.com/read/28465073/developmental-coordination-disorder-and-its-cause-the-road-less-travelled
#16
David Sugden
No abstract text is available yet for this article.
April 29, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28444245/can-a-community-of-practice-improve-physical-therapists-self-perceived-practice-in-developmental-coordination-disorder
#17
Chantal Camden, Lisa M Rivard, Karen Hurtubise, Léa Héguy, Jade Berbari
Background: Communities of practice (CoP ) are useful knowledge translation (KT) strategies but little is known about their impact on physical therapists' (PTs) self-perceived practice. Purpose: We evaluated the impact of a CoP on PTs' self-perceived practice, and explored factors influencing changes in self-perceived knowledge, skills, and practice related to developmental coordination disorder (DCD). Design: We used an explanatory sequential mixed-methods design, guided by The Theory of Reasoned Action and Theory of Planned Behavior...
April 21, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28440058/atypical-inter-hemispheric-communication-correlates-with-altered-motor-inhibition-during-learning-of-a-new-bimanual-coordination-pattern-in-developmental-coordination-disorder
#18
Mélody Blais, David Amarantini, Jean-Michel Albaret, Yves Chaix, Jessica Tallet
Impairment of motor learning skills in developmental coordination disorder (DCD) has been reported in several studies. Some hypotheses on neural mechanisms of motor learning deficits in DCD have emerged but, to date, brain-imaging investigations are scarce. The aim of the present study is to assess possible changes in communication between brain areas during practice of a new bimanual coordination task in teenagers with DCD (n = 10) compared to matched controls (n = 10). Accuracy, stability and number of mirror movements were computed as behavioural variables...
April 25, 2017: Developmental Science
https://www.readbyqxmd.com/read/28409696/collaborative-occupational-therapy-teachers-impressions-of-the-partnering-for-change-p4c-model
#19
A L Wilson, S R Harris
AIMS: Occupational therapists (OTs) often face barriers when trying to collaborate with teachers in school-based settings. Partnering for change (P4C), a collaborative practice model designed to support children with developmental coordination disorder, could potentially support all students with special needs. Therefore, the aim of this study was to explore how teachers experience OT services delivered using the P4C model to support children with a variety of special needs. METHODS: P4C was implemented at one elementary school in Courtenay, British Columbia...
April 14, 2017: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/28407444/familial-18q12-2-deletion-supports-the-role-of-rna-binding-protein-celf4-in-autism-spectrum-disorders
#20
Rita Barone, Marco Fichera, Mariaclara De Grandi, Marta Battaglia, Valeria Lo Faro, Teresa Mattina, Renata Rizzo
Deletion of 18q12.2 is an increasingly recognized condition with a distinct neuropsychiatric phenotype. Twenty-two patients have been described with overlapping neurobehavioral disturbances including developmental delay, intellectual disability of variable degree, seizures, motor coordination disorder, behavioral/emotional disturbances, and autism spectrum disorders. The CUGBP Elav-like family member 4 (CELF4) gene at 18q12.2 encodes a RNA-binding protein that links to RNA subsets involved in pre- and postsynaptic neurotransmission including almost 30% of potential autism-related genes...
June 2017: American Journal of Medical Genetics. Part A
keyword
keyword
67283
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"