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https://www.readbyqxmd.com/read/29673729/perinatal-outcomes-following-ivf-with-use-of-donor-versus-partner-sperm
#1
Mohan Shashikant Kamath, Belavendra Antonisamy, Hepsy Y Selliah, Antonio La Marca, Sesh Kamal Sunkara
It is a matter of interest whether pregnancies with the use of donor sperm are associated with a higher risk of adverse perinatal outcomes compared with partner sperm. Anonymized data were obtained from the Human Fertilization & Embryology Authority. Data from 1991 to 2011 involving a total of 95,787 singleton births (4523 with donor sperm and 91,264 with partner sperm) following fresh IVF/intracytoplasmic sperm injection (ICSI) were analysed to compare perinatal outcomes of preterm birth (PTB), low birthweight (LBW) and high birthweight (HBW)...
April 6, 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29649918/the-impact-of-unicornuate-uterus-on-perinatal-outcomes-after-ivf-icsi-cycles-a-matched-retrospective-cohort-study
#2
Xinxia Chen, Peihao Liu, Yan Sheng, Weiping Li, Rong Tang, Lingling Ding, Yingying Qin, Zi-Jiang Chen
OBJECTIVE: To evaluate the impact of unicornuate uterus on perinatal outcomes after in vitro fertilization and/or intracytoplasmic sperm injection (IVF/ICSI) cycles. METHODS: We performed a retrospective cohort study including 160 women with unicornuate uterus and 1:1 matched controls with normally shaped uterus. They received IVF/ICSI treatment during January 2009 and December 2011. The perinatal outcomes were followed up till December 2014. RESULTS: There were no significant differences in pregnancy rate, clinical pregnancy rate or live birth rate (53...
April 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29627351/placental-growth-factor-informed-management-of-suspected-pre-eclampsia-or-fetal-growth-restriction-the-mapple-cohort-study
#3
Andrew Sharp, Lucy C Chappell, Gustaaf Dekker, Sanja Pelletier, Yves Garnier, Onur Zeren, Katharina M Hillerer, Thorsten Fischer, Paul T Seed, Mark Turner, Andrew H Shennan, Zarko Alfirevic
OBJECTIVES: Placental Growth Factor (PlGF) has been shown to be beneficial in diagnosing pre-eclampsia. We performed a prospective cohort study of revealed PlGF in standard clinical use in four teaching hospitals in UK, Germany, Austria and Australia. STUDY DESIGN: Clinical data from women with suspected pre-eclampsia or fetal growth restriction <35 weeks' gestation with revealed PlGF measurement were collected (MAPPLE study). MAIN OUTCOME MEASURES: Data were compared to the PELICAN study (PlGF concealed)...
March 26, 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29626981/placental-lipoprotein-lipase-activity-is-positively-associated-with-newborn-adiposity
#4
Margaret J R Heerwagen, Diane L Gumina, Teri L Hernandez, Rachael E Van Pelt, Anita W Kramer, Rachel C Janssen, Dalan R Jensen, Theresa L Powell, Jacob E Friedman, Virginia D Winn, Linda A Barbour
INTRODUCTION: Recent data suggest that in addition to glucose, fetal growth is related to maternal triglycerides (TG). To reach the fetus, TG must be hydrolyzed to free fatty acids (FFA) and transported across the placenta, but regulation is uncertain. Placental lipoprotein lipase (pLPL) hydrolyzes TG, both dietary chylomicron TG (CM-TG) and very-low density lipoprotein TG (VLDL-TG), to FFA. This may promote fetal fat accretion by increasing the available FFA pool for placental uptake...
April 2018: Placenta
https://www.readbyqxmd.com/read/29616897/singleton-low-birthweight-rates-by-race-and-hispanic-origin-united-states-2006-2016
#5
Lindsay S Womack, Lauren M Rossen, Joyce A Martin
Low birthweight (LBW) is among the leading causes of infant death in the United States (1). LBW infants are also more likely to have health problems (2). After reaching its highest level in four decades, the LBW rate among all births declined from 2006 to 2014 (3,4), but the trend reversed in 2015 and 2016 when the LBW rate increased (4), moving further away from the Healthy People 2020 goal of reducing LBW rates to 7.8% of live births (5). This report shows trends in LBW, moderately low birthweight (MLBW), and very low birthweight (VLBW) by race and Hispanic origin from 2006 to 2016 for singleton births only, as rates of multiple births can impact LBW rates (4,6)...
March 2018: NCHS Data Brief
https://www.readbyqxmd.com/read/29581725/comparison-of-the-screening-tests-for-gestational-diabetes-mellitus-between-one-step-and-two-step-methods-among-thai-pregnant-women
#6
Suchaya Luewan, Phenphan Bootchaingam, Theera Tongsong
Objective: To compare the prevalence and pregnancy outcomes of GDM between those screened by the "one-step" (75 gm GTT) and "two-step" (100 gm GTT) methods. Methods: A prospective study was conducted on singleton pregnancies at low or average risk of GDM. All were screened between 24 and 28 weeks, using the one-step or two-step method based on patients' preference. The primary outcome was prevalence of GDM, and secondary outcomes included birthweight, gestational age, rates of preterm birth, small/large-for-gestational age, low Apgar scores, cesarean section, and pregnancy-induced hypertension...
2018: Obstetrics and Gynecology International
https://www.readbyqxmd.com/read/29561286/top-five-legal-pitfalls-in-retinopathy-of-prematurity
#7
Darius M Moshfeghi
PURPOSE OF REVIEW: This review highlights the common areas of medicolegal risk during retinopathy of prematurity (ROP) screening. RECENT FINDINGS: Most malpractice risk in ROP comes from systemic errors that ultimately result in failure to screen the patient in a timely fashion, resulting in failures to intervene and/or refer in a timely fashion. Currently, the emphasis is engaging the family members, the hospital staff, and clinic staff to pro-actively manage ROP patients and ensure that they are screened in a timely fashion...
May 2018: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29549372/long-term-neurodevelopmental-outcomes-of-premature-infants-in-singapore
#8
Charmaine M Teo, Woei Bing Poon, Selina Ky Ho
INTRODUCTION: Neonatal care advances have resulted in improved survival but have raised concerns of increase in neurodevelopmental impairment. This study looked at long-term neurodevelopmental outcomes at ages 5 and 8 years of very low birthweight infants born in the 2000s as compared to the 1990s. Neurodevelopmental assessment at 2 years old was compared to that at 5 and 8 years to determine if assessment at 2 years was predictive of later outcomes. MATERIALS AND METHODS: A retrospective cohort study of consecutive infants with birthweight less than 1250 grams admitted to a tertiary centre in Singapore between January 1994 to December 1995 (Epoch I) and January 2004 to December 2005 (Epoch II) were included...
February 2018: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29518647/vitamin-d-deficiency-and-respiratory-morbidity-among-african-american-very-low-birth-weight-infants
#9
S Nadya J Kazzi, Sreenivas Karnati, Subhash Puthuraya, Ronald Thomas
BACKGROUND: Very low birth weight infants (VLBWI) have unexplained variation in respiratory morbidity, including respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD). We examined a potential association to serum 25-hydroxyvitamin D (s-25OHD) on day one. STUDY DESIGN: Prospective, observational study on 89 VLBWI (≤1250 g). S-25OHD (day one and 21) and respiratory severity score (RSS) (day one) were examined. Other respiratory morbidities including BPD were compared between infants with s-25OHD ≤ 10 ng/ml (deficient) versus >10 ng/ml (adequate)...
April 2018: Early Human Development
https://www.readbyqxmd.com/read/29503275/feasibility-of-helmet-delivered-continous-positive-airway-pressure-in-very-low-birthweight-infants
#10
Almudena Alonso-Ojembarrena, Antonio Segado-Arenas, Isabel Benavente-Fernández, Simón Pedro Lubián-López
We describe our experience with helmet-delivered continuous positive airway pressure in five preterm newborns. We analyzed oxygen requirement, arterial oxygen saturation, respiratory rate, medium arterial pressure, heart rate, apneic spells and patient's comfort. The patients' vital signs or pain scale were not different before and after treatment.
February 15, 2018: Indian Pediatrics
https://www.readbyqxmd.com/read/29470268/facilitating-early-breast-milk-expression-in-mothers-of-very-low-birth-weight-infants
#11
Leslie Ann Parker, Jacqueline Hoffman, Ashley Darcy-Mahoney
BACKGROUND: Although early initiation of human milk (HM) expression after birth is known to increase lactation success in mothers of very low birthweight (VLBW) infants, initiation is frequently delayed, potentially decreasing both short- and long-term HM production. Obstetrical (OB) nurses are typically the healthcare provider responsible for facilitating the initial HM expression session. As delays in initiation are common, it is likely that nurses experience obstacles to facilitation of an early initiation of HM expression...
March 2018: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/29401677/adverse-pregnancy-outcomes-among-adolescents-in-northwest-russia-a-population-registry-based-study
#12
Anna A Usynina, Vitaly Postoev, Jon Øyvind Odland, Andrej M Grjibovski
This study aimed to assess whether adolescents have an increased risk of adverse pregnancy outcomes (APO) compared to adult women. We used data on 43,327 births from the population-based Arkhangelsk County Birth Registry, Northwest Russia, for 2012-2014. The perinatal outcomes included stillbirth, preterm birth (<37 and <32 weeks), low and very low birthweight, 5 min Apgar score <7 and <4, perinatal infections, and the need for neonatal transfer to a higher-level hospital. Multivariable logistic regression was applied to assess the associations between age and APO...
February 3, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29394356/carriage-of-cronobacter-sakazakii-in-the-very-preterm-infant-gut
#13
Sukantha Chandrasekaran, Carey-Ann D Burnham, Barbara B Warner, Phillip I Tarr, Todd N Wylie
Background: Cronobacter sakazakii causes severe neonatal infections, but we know little about gut carriage of this pathogen in very low birthweight infants. Methods: We sequenced 16S rRNA genes from 2,304 stools from 121 children at St. Louis Children's Hospital whose birthweight was ≤1,500 grams, attempted to isolate C. sakazakii from 157 of these stools, genome sequenced the recovered isolates, and sought correlations between indices of Cronobacter excretion, host characteristics and unit formula use...
January 31, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29377728/milk-volume-at-2-weeks-predicts-mother-s-own-milk-feeding-at-neonatal-intensive-care-unit-discharge-for-very-low-birthweight-infants
#14
Rebecca Hoban, Harold Bigger, Michael Schoeny, Janet Engstrom, Paula Meier, Aloka L Patel
OBJECTIVE: This study sought to determine the maternal prepregnancy, pregnancy, and delivery risk factors that predicted coming to volume (CTV; achieving pumped mother's own milk [MOM] volume ≥500 mLs/day) and the continuation of MOM provision through to discharge from the neonatal intensive care unit (NICU) in mothers and their very low birthweight (VLBW; <1,500 g at birth) infants. STUDY DESIGN: Secondary analysis of prospectively collected data from 402 mothers of VLBW infants admitted to an urban NICU, including detailed MOM pumping records for a subset (51%) of the cohort...
January 29, 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29374641/successful-percutaneous-drainage-of-pneumatoceles-in-an-extremely-low-birthweight-infant
#15
Jogender Kumar, Kanya Mukhopadhyay, Anmol Bhatia
Pneumatoceles are thin-walled, air-filled cystic lesions developing within the lung parenchyma. It used to be a relatively common entity in the presurfactant era when preterm babies were ventilated at an unacceptably high positive pressure for respiratory distress syndrome. Pneumatocele formation is a very rare complication of pneumonia in neonates. We here report a case of extremely low-birthweight (ELBW) neonate who developed large bilateral pneumatoceles after staphylococcal pneumonia. Hereby, we present a case of an ELBW infant with bilateral massive pneumatoceles who underwent successful percutaneous catheter drainage to decompress these pneumatoceles...
January 26, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29350401/neurodevelopmental-outcome-in-very-preterm-and-very-low-birthweight-infants-born-over-the-past-decade-a-meta-analytic-review
#16
REVIEW
Aurelie Pascal, Paul Govaert, Ann Oostra, Gunnar Naulaers, Els Ortibus, Christine Van den Broeck
AIM: The purpose of this systematic review was to provide an up-to-date global overview of the separate prevalences of motor and cognitive delays and cerebral palsy (CP) in very preterm (VPT) and very-low-birthweight (VLBW) infants. METHOD: A comprehensive search was conducted across four databases. Cohort studies reporting the prevalence of CP and motor or cognitive outcome from 18 months corrected age until 6 years of VPT or VLBW infants born after 2006 were included...
April 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29349938/improved-regional-disparities-in-neonatal-care-by-government-led-policies-in-korea
#17
In Gyu Song, Seung Han Shin, Han Suk Kim
BACKGROUND: Although the number of high-risk neonates has increased in Korea, hospitals were reluctant to open or maintain neonatal intensive care unit (NICU) due to the low medical cost. Consequently, there were regional disparities in facilities, equipment, and neonatal health outcomes. For these reasons, the Korean government began to invest in neonatal care during the last decade. We identified the status of NICUs in Korea and assessed changes after the government-driven policies...
February 5, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29341395/health-of-southern-tasmanian-4-to-6-year-old-children-in-out-of-home-care-compared-to-peers
#18
Marie Rauter, Anagha Jayakar, Tom Clemens, Zaharenia Galanos, Louise Newbery, Andrew Whelan
AIM: To compare the health of 4- to 6-year-old children in out-of-home care (OOHC) in Southern Tasmania with their peers. METHODS: Demographic and health data collection and prospective health assessment of all 4- to 6-year olds in OOHC in Southern Tasmania on 30 August 2011 was undertaken. Data were compared to Tasmanian and/or Australian peers. RESULTS: A total of 109 of 129 children aged 4 to 6 years were included in the study. Time in OOHC was on average 38 (range 0-76) months...
January 17, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29303230/planned-birth-at-or-near-term-for-improving-health-outcomes-for-pregnant-women-with-gestational-diabetes-and-their-infants
#19
REVIEW
Linda M Biesty, Aoife M Egan, Fidelma Dunne, Eugene Dempsey, Pauline Meskell, Valerie Smith, G Meabh Ni Bhuinneain, Declan Devane
BACKGROUND: Gestational diabetes is a type of diabetes that occurs during pregnancy. Women with gestational diabetes are more likely to experience adverse health outcomes such as pre-eclampsia or polyhydramnios (excess amniotic fluid). Their babies are also more likely to have health complications such as macrosomia (birthweight > 4000 g) and being large-for-gestational age (birthweight above the 90th percentile for gestational age). Current clinical guidelines support elective birth, at or near term in women with gestational diabetes to minimise perinatal complications, especially those related to macrosomia...
January 5, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29300996/factors-associated-with-time-to-full-feeds-in-preterm-very-low-birth-weight-infants
#20
Gaurav Patwardhan, Ankit Soni, Nitin Rachwani, Sandeep Kadam, Sanjay Patole, Anand Pandit
Background: Feeding intolerance prolongs time to full feeds (TFFs) in preterm infants. We studied factors associated with TFF in preterm infants on standardized feeding regimen (SFR) and routine probiotic supplementation (RPS). Methods: This is a prospective cohort study of preterm infants ≤1500 g. Pearson's correlation, Mann-Whitney test and multivariate analysis were used. Results: In total, 37 of 304 admitted infants died before reaching full feeds...
December 28, 2017: Journal of Tropical Pediatrics
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