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Very low birthweight

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https://www.readbyqxmd.com/read/28077516/early-onset-invasive-candidiasis-in-extremely-low-birth-weight-infants-perinatal-acquisition-predicts-poor-outcome
#1
Michelle Barton, Alex Shen, Karel O'Brien, Joan L Robinson, H Dele Davies, Kim Simpson, Elizabeth Asztalos, Joanne Langley, Nicole Le Saux, Reginald Sauve, Anne Synnes, Ben Tan, Louis de Repentigny, Earl Rubin, Chuck Hui, Lajos Kovacs, Yvonne Cw Yau, Susan E Richardson
BACKGROUND: Neonatal invasive candidiasis (IC)presenting in the first week of life is less common and less well described than later onset IC. Risk factors, clinical features and disease outcomeshave not been studied in early onset disease (EOD, ≤7d) or compared to late onset disease (LOD, >7d). METHODS: All extremely low birth weight (ELBW, <1000g) cases with IC and controls froma multicentre study of neonatal candidiasisenrolledfrom 2001 to 2003were included in this study...
January 11, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28068533/the-weight-of-inequalities-duration-of-residence-and-offspring-s-birthweight-among-migrant-mothers-in-sweden
#2
Sol P Juárez, Anders Hjern
In this study we assessed the effect duration of residence on the association between maternal origin and birthweight in Sweden. Considering sibling information, we also investigated how far the presence or lack of such an effect could be biased by the use of cross-sectional data, since there may be a selection among those mothers who decide to have a child soon after moving to the country (e.g. those with a more stable family situation). Using the Swedish Medical Birth Register for the period 1992-2012, we performed linear and multinomial regressions, multilevel linear regressions, and random effect meta-analysis...
December 30, 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/28050900/planned-early-birth-versus-expectant-management-waiting-for-prelabour-rupture-of-membranes-at-term-37-weeks-or-more
#3
REVIEW
Philippa Middleton, Emily Shepherd, Vicki Flenady, Rosemary D McBain, Caroline A Crowther
BACKGROUND: Prelabour rupture of membranes (PROM) at term is managed expectantly or by planned early birth. It is not clear if waiting for birth to occur spontaneously is better than intervening, e.g. by inducing labour. OBJECTIVES: The objective of this review is to assess the effects of planned early birth (immediate intervention or intervention within 24 hours) when compared with expectant management (no planned intervention within 24 hours) for women with term PROM on maternal, fetal and neonatal outcomes...
January 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28046205/dietary-advice-interventions-in-pregnancy-for-preventing-gestational-diabetes-mellitus
#4
REVIEW
Joanna Tieu, Emily Shepherd, Philippa Middleton, Caroline A Crowther
BACKGROUND: Gestational diabetes mellitus (GDM) is a form of diabetes occurring during pregnancy which can result in short- and long-term adverse outcomes for women and babies. With an increasing prevalence worldwide, there is a need to assess strategies, including dietary advice interventions, that might prevent GDM. OBJECTIVES: To assess the effects of dietary advice interventions for preventing GDM and associated adverse health outcomes for women and their babies...
January 3, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28043190/echocardiographic-assessment-of-patent-ductus-arteriosus-in-very-low-birthweight-infants-over-time-prospective-observational-study
#5
Sook Kyung Yum, Cheong-Jun Moon, Young-Ah Youn, Jae Young Lee, In Kyung Sung
BACKGROUND: We aimed to determine the echocardiographic parameters that can predict the presence of patent ductus arteriosus(PDA) and haemodynamically significant ductus arteriosus(HSDA) at different time points. METHODS: Echocardiogram was performed on postnatal days 3 and 7(D3-Echo and D7-Echo, respectively) in 71 very low birthweight infants with a median gestational age of 28.0 weeks. We first assessed the correlation between D3-Echo findings among infants with ductal patency and persistent ductal patency on D7-Echo...
January 2, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28011792/high-flow-nasal-cannula-versus-ncpap-duration-to-full-oral-feeds-in-preterm-infants-a-randomised-controlled-trial
#6
Sinead J Glackin, Anne O'Sullivan, Sherly George, Jana Semberova, Jan Miletin
OBJECTIVE: To compare the time taken by preterm infants with evolving chronic lung disease to achieve full oral feeding when supported with humidified high flow nasal cannula (HFNC) or nasal continuous positive airway pressure (NCPAP). DESIGN: Single centre randomised controlled trial. SETTING: Level III neonatal intensive care unit at the Coombe Women and Infants University Hospital, Dublin, Ireland. PATIENTS: Very low birthweight (birth weight <1500 g) infants born before 30 weeks' gestation who were NCPAP-dependent at 32 weeks corrected gestational age were eligible to participate...
December 23, 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/27936018/stillbirths-at-term-case-control-study-of-risk-factors-growth-status-and-placental-histology
#7
Federico Mecacci, Caterina Serena, Laura Avagliano, Mauro Cozzolino, Eleonora Baroni, Marianna Pina Rambaldi, Serena Simeone, Francesca Castiglione, Gian Luigi Taddei, Gaetano Bulfamante
OBJECTIVE: To investigate the proportion of stillbirths at term associated with abnormal growth using customized birth weight percentiles and to compare histological placental findings both in underweight stillborn fetuses and in live births. METHODS: A retrospective case-control study of 150 singleton term stillbirths. The livebirth control groups included 586 cases of low-risk pregnancies and 153 late fetal growth restriction fetuses. Stillbirths and livebirths from low-risk pregnancies were classified using customized standards for fetal weight at birth, as adequate for gestational age (AGA; 10-90th percentile), small (SGA; <10th percentile) or large for gestational age (LGA; >90th percentile)...
2016: PloS One
https://www.readbyqxmd.com/read/27907284/working-memory-in-very-low-birthweight-children-at-the-age-of-11-years
#8
Satu Korpela, Anna Nyman, Petriina Munck, Annarilla Ahtola, Jaakko Matomäki, Tapio Korhonen, Riitta Parkkola, Leena Haataja
The aim of this study is to investigate the working memory (WM) of very-low-birthweight (VLBW, ≤ 1500 g) children at the age of 11 years using Baddeley's WM model. A regional cohort of 95 VLBW children was assessed for the domains of the WM model (central executive [CE], visuospatial sketchpad [VS], and phonological loop [PL]) using subtests from the Working Memory Test Battery for Children (WMTB-C) and the Wechsler Intelligence Scale for Children - Fourth Edition (WISC-IV). VLBW children were categorized into three groups according to their degree of brain pathology (normal, minor, or major) in neonatal brain magnetic resonance imaging at the term age, and the WM performance was compared between groups to test norms...
December 1, 2016: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/27882544/prospective-evaluation-of-the-ages-and-stages-questionnaire-3rd-edition-in-very-low-birthweight-infants
#9
Pratibha K Agarwal, Luming Shi, Lourdes M Daniel, Phey Hong Yang, Poh Choo Khoo, Bin Huey Quek, Qishi Zheng, Victor S Rajadurai
AIM: To evaluate the predictive and concurrent diagnostic agreement of the Ages and Stages Questionnaire 3rd Edition (ASQ-3) with the Bayley Scales of Infant and Toddler Development 3rd Edition (Bayley-III) in infants born preterm and very-low-birthweight (PT/VLBW; ≤1250g). METHOD: We evaluated 141 PT/VLBW infants (68 males, 73 females) born at the KK Women's and Children's Hospital between January 2010 and December 2011, to determine predictive and concurrent diagnostic agreement between the ASQ-3 at 9, 12, 18, and 24 months corrected age and Bayley-III at 24 months...
November 24, 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27873371/getting-a-sporting-chance-title-ix-and-the-intergenerational-transmission-of-health
#10
Lisa Schulkind
We know that healthier mothers tend to have healthier infants, but we do not know how much of that relationship reflects the intergenerational transmission of genetic attributes versus environmental influences. From a policy perspective, it is crucial to understand which environmental influences are important and whether investments in one generation affect outcomes for the next. I use variation in the implementation of Title IX to measure the effects of increased athletic opportunities on the health of infants...
November 22, 2016: Health Economics
https://www.readbyqxmd.com/read/27864000/timing-of-initiation-of-antiretroviral-therapy-and-adverse-pregnancy-outcomes-a-systematic-review-and-meta-analysis
#11
Olalekan A Uthman, Jean B Nachega, Jean Anderson, Steve Kanters, Edward J Mills, Françoise Renaud, Shaffiq Essajee, Meg C Doherty, Lynne M Mofenson
BACKGROUND: Although lifelong combination antiretroviral therapy (ART) is recommended for all individuals with HIV, few data exist for pregnancy outcomes associated with ART initiation before conception. We assessed adverse pregnancy outcomes associated with ART initiated before conception compared with that of ART started after conception. METHODS: We did a systematic review of studies from low-income, middle-income, and high-income countries by searching the Cochrane Central Register of Controlled Trials, Embase, LILACS, MEDLINE, Toxline, Web of Knowledge, and WHO Global Index Medicus and trials in progress (International Clinical Trials Registry Platform) for randomised trials, quasi-randomised trials, and prospective cohort studies done between Jan 1, 1980, and June 1, 2016, in which timing of ART initiation in pregnant women living with HIV was reported...
January 2017: Lancet HIV
https://www.readbyqxmd.com/read/27828937/ethyl-linolenate-is-elevated-in-meconium-of-very-low-birth-weight-neonates-exposed-to-alcohol-in-utero
#12
Teresa S Gross, Frank Harris, Lou Ann S Brown, Theresa W Gauthier
BACKGROUND: The health implications of in utero alcohol exposure have been difficult to study in very-low-birth-weight newborns (VLBW) because of an inability to identify maternal alcohol exposure. Fatty acid ethyl esters (FAEEs) are elevated in meconium of alcohol-exposed term newborns. We hypothesized that meconium FAEEs would be similarly elevated in alcohol-exposed VLBW premature newborns. METHODS: In a retrospective cohort study of 64 VLBW neonates, newborns were classified into Non-Exposed, Any Exposure, or Weekly Exposure groups based on an in-depth structured maternal interview...
December 14, 2016: Pediatric Research
https://www.readbyqxmd.com/read/27809613/in-resource-limited-areas-complete-enteral-feed-in-stable-very-low-birth-weight-infants-1000-1500%C3%A2-g-started-within-24%C3%A2-h-of-life-can-improve-nutritional-outcome
#13
Reeta Bora, Nishchay B Murthy
OBJECTIVE: To evaluate feasibility of complete enteral feed (CEF) in stable very low birth weight neonates weighing 1000-1500 g. SUBJECTS AND INTERVENTIONS: One hundred and three stable very low birth weight (vlbw) neonates (1000-1500 g) irrespective of gestational age (GA) were randomized to receive either CEF with expressed breast milk (EBM) (n = 51) or minimal enteral feed (MEF) supplemented with intravenous fluid (IVF). (MEF) (n = 52). Feed volume was increased progressively...
November 29, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27806990/influence-of-own-mother-s-milk-on-bronchopulmonary-dysplasia-and-costs
#14
Aloka L Patel, Tricia J Johnson, Beverley Robin, Harold R Bigger, Ashley Buchanan, Elizabeth Christian, Vikram Nandhan, Anita Shroff, Michael Schoeny, Janet L Engstrom, Paula P Meier
BACKGROUND: Human milk from the infant's mother (own mother's milk; OMM) feedings reduces the risk of several morbidities in very low birthweight (VLBW) infants, but limited data exist regarding its impact on bronchopulmonary dysplasia (BPD). OBJECTIVE: To prospectively study the impact of OMM received in the neonatal intensive care unit (NICU) on the risk of BPD and associated costs. DESIGN/METHODS: A 5-year prospective cohort study of the impact of OMM dose on growth, morbidity and NICU costs in VLBW infants...
November 2, 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/27699897/childhood-body-mass-is-positively-associated-with-cesarean-birth-in-yucatec-maya-subsistence-farmers
#15
Amanda Veile, Karen L Kramer
OBJECTIVE: The epidemiologic link between cesarean birth and childhood obesity is unresolved, partly because most studies come from industrialized settings where many post-birth factors affect the risk for obesity. We take advantage of an unusual ethnographic situation where hospital and cesarean birth modes have recently been introduced among Yucatec Maya subsistence farmers, but young children have had minimal exposure to the nutritional transition. While we expect to find very low rates of childhood obesity, we predict that cesarean-born children will be larger and heavier than vaginally born children...
October 4, 2016: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/27677342/group-b-streptococcus-late-onset-sepsis-in-very-low-birth-weight-newborns-10-years-experience
#16
Francesco M Risso, Elio Castagnola, Roberto Bandettini, Diego Minghetti, Laura Pagani, Luca A Ramenghi
PURPOSE: The incidence of late-onset neonatal infection (LONS) group B streptococcus (GBS) in very low birthweight (VLBW) is still matter of debate. In the present 10-years retrospective study we investigated the epidemiology of GBS LONS in VLBW neonates. MATERIALS AND METHODS: From January 2006 to July 2015 we conducted a retrospective study in all preterm infants admitted at our third level referral center for neonatal intensive care (NICU). From our database we were able to retrieve all cases of bloodstream infections/meningitis GBS positive...
September 27, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27671836/two-hourly-versus-3-hourly-feeding-for-very-low-birthweight-infants-a-randomised-controlled-trial
#17
Nor Rosidah Ibrahim, Tan Hooi Kheng, Ariffin Nasir, Noraida Ramli, Jimmy Lee Kok Foo, Sharifah Huda Syed Alwi, Hans Van Rostenberghe
OBJECTIVE: To determine whether feeding with 2-hourly or 3-hourly feeding interval reduces the time to achieve full enteral feeding and to compare their outcome in very low birthweight preterm infants. DESIGN: Parallel-group randomised controlled trial with a 1:1 allocation ratio. SETTING: Two regional tertiary neonatal intensive care units. PATIENTS: 150 preterm infants less than 35 weeks gestation with birth weight between 1...
September 26, 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/27623808/a-quality-improvement-initiative-for-delayed-umbilical-cord-clamping-in-very-low-birthweight-infants
#18
Jeff Bolstridge, Tracy Bell, Barbara Dean, Amy Mackley, Gina Moore, Cheryl Swift, Dina Viscount, David A Paul, Stephen A Pearlman
BACKGROUND: Due to clinical benefits, delayed cord clamping (DCC) is recommended in infants born before 37 weeks gestational age. The objective was to institute a delayed cord clamping program and to evaluate clinical outcomes one year after initiation. METHODS: This study occured at Christiana Care Health System, a tertiary care facility with a 52 bed level 3 Neonatal Intensive Care Unit (NICU). A multidisciplinary team created a departmental policy, a DCC protocol and educational programs to support the development of a DCC program...
September 13, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27601464/adrenocortical-insufficiency-and-refractory-hypotension-in-preterm-infants
#19
Pak Cheung Ng
Preterm, very low birthweight (VLBW) infants are prone to life-threatening hypotension secondary to hypothalamic-pituitary-adrenal axis immaturity, resulting in adrenocortical insufficiency. Clinical presentations of inotrope-resistant refractory hypotension are usually evident, but interpretation of serum cortisol may pose much difficulty to front-line neonatologists. This review examines the salient pathophysiology of adrenocortical insufficiency in the immediate postnatal period, characterises its endocrinological abnormalities, and describes the typical and variant clinical presentations...
September 6, 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/27590475/insertion-of-peripherally-inserted-central-catheters-in-neonates-less-than-1-5%C3%A2-kg-using-ultrasound-guidance
#20
Kevin N Johnson, Tina Thomas, Jason Grove, Marcus D Jarboe
BACKGROUND: Neonates commonly require central access, and in those with very low or extremely low birthweight this can be challenging. Described here is a technique that uses ultrasound guidance in the placement of peripherally inserted central catheters (PICC) in neonates and an analysis of outcomes. METHODS: A retrospective chart review was conducted of all patients below 1500 g that underwent placement of a peripherally inserted central catheter under ultrasound guidance between January 1, 2012, and December 31, 2014 at a single center...
November 2016: Pediatric Surgery International
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