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Stefano Telera, Alfredo Pompili, Francesco Crispo, Maddalena Giovannetti, Andrea Pace, Veronica Villani, Alessandra Fabi, Isabella Sperduti, Laura Raus
OBJECTIVES: Balloon Kyphoplasty (BKP) for vertebral compression fractures (VCFs) in cancer patients is more challenging than for osteoporotic ones. Cord compressions are frequent and the incidence of complications ten-fold greater. Polymethylmetacrylate (PMMA) is the gold standard material for BKP but has disadvantages: exothermic reaction, short working time, rapid solidification, absence of osteoconduction. VK100 is a mixture of Dimethyl Methylvinyl siloxane and Barium Sulphate. It is elastic, adhesive to bone, leaves 30 min before solidification without exothermic reaction, and shows a stiffness close to the intact vertebrae...
June 15, 2018: Clinical Neurology and Neurosurgery
Zhirong Wang, Wen Zhang, Hao Xu, Aiqing Lu, Huilin Yang, Zong-Ping Luo
BACKGROUND: Cannulating fenestrated pedicle screws are effective for fixating osteoporotic vertebrae. However, a major limitation is the excessive pressure required to inject a sufficient amount of cement into the vertebral body through the narrow hole of a pedicle screw. We have recently proposed a new cannulating fenestrated pedicle screw with a large hole diameter and a matched inner pin for screw-strength maintenance. Our purpose was to determine whether the new screw can significantly reduce bone-cement perfusion pressure during cement augmentation, METHODS: Two different methods were used to examine perfusion pressure...
June 18, 2018: Clinical Biomechanics
Bowen Hu, Xi Yang, Huiliang Yang, Limin Liu, Peiran Chen, Linnan Wang, Ce Zhu, Chunguang Zhou, Yueming Song
BACKGROUND: Choosing the fusion level for posterior fusion in Lenke 5C adolescent idiopathic scoliosis patients is highly associated with coronal balance. Previous studies indicated that in patients with lowest end vertebra tilt > 25°, surgeons could extend distal fusion to avoid coronal imbalance. This study aimed to assess the risk factors for coronal imbalance in Lenke 5C scoliosis, and to discuss how to select fusion level. METHODS: We reviewed 59 Lenke 5C AIS patients in one institution with at least 2-years' follow-up from 2010 through 2015...
June 18, 2018: World Neurosurgery
Keun Lee, Nitin Adsul, Hyeun-Sung Kim, Yong-Hun Pee, Kwang Lae Lee, Il-Tae Jang
BACKGROUND: In cases of Kümmell's disease without neuro deficit, percutaneous vertebroplasty or Kyphoplasty have achieved short-term favorable outcomes. In the long term, re-collapse of the augmented vertebral body and aggravation of the kyphosis at the index level is often reported. On the other hand, owing to medical comorbidities, the elderly are often not suited for extensive open spine surgery under general anesthesia. CASE DESCRIPTION: A 95-year-old man presented with a one-month history of intractable back pain and gait disturbance...
June 18, 2018: World Neurosurgery
Shaoqian Wang, Hui Wang, Lei Niu
The clinical efficacy of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in the treatment of osteoporotic vertebral compression fractures after bilateral resection of ovarian cancer was investigated. Eighty-six patients with osteoporotic vertebral compression fractures after bilateral resection of ovarian cancer admitted to the Second People's Hospital of Hefei from September, 2015 to August, 2016 were selected and randomly divided into control group (n=43) and observation group (n=43)...
July 2018: Oncology Letters
Ella Been, Sara Shefi, Leonid Kalichman, Jeannie F Bailey, Michalle Soudack
Spinal muscle cross-sectional area has been highly associated with spinal pathology. Despite the medium-high prevalence of spinal pathology in children, there is very limited knowledge regarding muscle size and growth pattern in individuals younger than 20 years of age. The aim of this study is to analyze the change in size and symmetry of spinal muscles (erector spinae, multifidus, psoas and quadratus lumborum) in children 2-20 years of age. We studied reformatted images from 91 abdominal computed tomographic scans of children aged 2-20 years, from an existing imaging dataset...
June 21, 2018: Journal of Anatomy
L L Zhang, L Ni, X D Cui, H Liu, B Meng, H L Yang
Objective: To observe the clinical characteristics of thoracolumbar vertebral fracture cascade, analyze the relationship between the baseline fractures and the subsequent fractures and compare the distribution differences of subsequent fractures following vertebral augmentation or non-operation. Methods: From July 2012 to August 2016, 1 363 patients admitted to the First Affiliated Hospital of Soochow University with vertebral augmentation for the treatment of vertebral fractures were retrospectively analyzed...
June 19, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
H D Bao, S B Shu, J Shi, S N Liu, M H Sun, A N Hu, Z Liu, Z Z Zhu, B P Qian, Y Qiu
Objective: To analyze the preoperative axial plane and the surgical outcomes of the Lenke type 1A patients with adolescent idiopathic scoliosis (AIS) whose coronal curve type was matched but thoracic kyphosis (TK) was different. Methods: This study retrospectively reviewed a series of Lenke type 1A female AIS patients who underwent corrective surgery in the Department of Spine Surgery of Nanjing Drum Tower Hospital from May to August 2017. After matched with the Cobb angle of the main thoracic curve, the apical vertebral, the vertebra number included in the curve, the lumber modifier in the Lenke classification and Risser sign, 12 pairs of AIS patients, whose coronal curve was matched but thoracic kyphosis was different, were included in this study...
June 5, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Nathaly Cortez-Bazán, Jennifer R Delgado, Omar Galdos, Luis Huicho
Pott's disease is a health problem in developing countries and its diagnosis in children is a challenge. Here we present the case of a two-year-old boy with Pott's disease involving T1 to T3 thoracic vertebrae. The clinical presentation was characterized by difficulty walking, fever, cough, and dyspnea. At physical examination, kyphosis and bony prominence were observed in the cervicodorsal area. A positive tuberculin test was obtained, and Mycobacterium tuberculosis was isolated via culture of the gastric aspiration sample...
January 2018: Revista Peruana de Medicina Experimental y Salud Pública
Joshua Shubert, Muyinatu A Lediju Bell
It is well known that there are structural differences between cortical and cancellous bone. However, spinal surgeons currently have no reliable method to non-invasively determine these differences in real-time when choosing the optimal starting point and trajectory to insert pedicle screws and avoid surgical complications associated with breached or weakened bone. This paper explores 3D photoacoustic imaging of a human vertebra to noninvasively differentiate cortical from cancellous bone for this surgical task...
June 20, 2018: Physics in Medicine and Biology
Murat Ulutaş, Mustafa Özkaya, Onur Yaman, Teyfik Demir
Transforaminal lumbar interbody fusion was an alternative to posterior lumbar interbody fusion for decompression surgeries. This study investigates the biomechanical responses of the unilateral and bilateral pedicle screw fixations with/without transforaminal lumbar interbody fusion cages under axial compression, flexion, and torsional loads. Ovine vertebrae were used in this study. Cadavers, randomly divided into five, were intact control group, bilateral pedicle screw fixation group, bilateral pedicle screw fixation group with transforaminal lumbar interbody fusion cage, unilateral pedicle screw fixation group, and unilateral pedicle screw fixation group with transforaminal lumbar interbody fusion cage...
June 1, 2018: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
Zhigang Li, Xiaoqiang Han, Cheng Ji, Xinfeng Han
Cervical spinal injuries of children in motor vehicle crashes have high morbidity and mortality rates. Cervical vertebrae change rapidly in both size and shape during growth. To accurately assess the risk of spinal injury for children of different ages, it is necessary to understand how the spatial geometric features of vertebrae change with the child's age and neck size. In this study, an innovative semi-automated method was developed that can extract and align geometric points from computed tomography scans to accurately represent complex three-dimensional vertebral geometry...
June 19, 2018: Annals of Biomedical Engineering
Yeliz Akturk, Serra Ozbal Gunes
PURPOSE: This study aims to determine the normal limits of atlanto-dental interval (ADI), basion-dens interval (BDI), basion-cartilaginous dens interval (BCDI), and prevertebral soft tissue thickness (PVSTT) according to age groups for normal pediatric cases. MATERIALS AND METHODS: CT images of 256 pediatric patients aged between 1 and 15 years were retrospectively evaluated. ADI, BDI, BCDI and PVSTT measurements were performed. RESULTS: Upper normal limit (UNL) values for ADI were 2...
June 19, 2018: Japanese Journal of Radiology
John M DeSesso, Anthony R Scialli
Evaluation of the skeleton in laboratory animals is a standard component of developmental toxicology testing. Standard methods of performing the evaluation have been established, and modification of the evaluation using imaging technologies is under development. The embryology of the rodent, rabbit, and primate skeleton has been characterized in detail and summarized herein. The rich literature on variations and malformations in skeletal development that can occur in the offspring of normal animals and animals exposed to test articles in toxicology studies is reviewed...
June 19, 2018: Birth Defects Research
Thomas J Buell, Avery L Buchholz, John C Quinn, Jeffrey P Mullin, Juanita Garces, Marcus D Mazur, Mark E Shaffrey, Chun-Po Yen, Christopher I Shaffrey, Justin S Smith
Pedicle subtraction osteotomy (PSO) is an effective technique to correct fixed sagittal malalignment. A variation of this technique, the "trans-discal" or "extended" PSO (Schwab grade IV osteotomy), involves extending the posterior wedge resection of the index vertebra to include the superior adjacent disc for radical discectomy. The posterior wedge may be resected in asymmetric fashion to correct concurrent global coronal malalignment.This video illustrates the technical nuances of an extended asymmetrical lumbar PSO for adult spinal deformity...
June 16, 2018: Operative Neurosurgery (Hagerstown, Md.)
Mu Qiao, Bang-Ping Qian, Shi-Zhou Zhao, Yong Qiu, Bin Wang, Jun Jiang
OBJECTIVE: To compare the efficacy of long and short segment instrumentation following pedicle subtraction osteotomy (PSO) for thoracolumbar kyphosis caused by ankylosing spondylitis (AS). METHODS: Sixty-four consecutive AS patients were analyzed and divided into groups according to length of instrumentation. We defined short segment instrumentation (SSI) as construct length less than 7 levels (3 levels above and below the osteotomy or less) (n=17). In contrast, long segment instrumentation (LSI) was defined as construct length equal to or greater than 7 levels (4 levels above and 3 levels below the osteotomy or more) (n=47)...
June 16, 2018: World Neurosurgery
Azadeh Abravan, Hanne Astrid Eide, Ayca Muftuler Løndalen, Åslaug Helland, Eirik Malinen
PURPOSE: To map functional bone marrow (BM) by 2-deoxy-2-[18 F]fluoro-D-glucose ([18 F]FDG) positron emission tomography (PET) in the vertebral column of lung cancer patients prior to, during, and after treatment. Moreover, to identify radiation- and erlotinib-induced changes in the BM. PROCEDURES: Twenty-six patients with advanced non-small cell lung cancer, receiving radiotherapy (RT) alone or concomitantly with erlotinib, were examined by [18 F]FDG PET before, during, and after treatment...
June 18, 2018: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
Zubair Khan, Nauman Siddiqui, Muhammad Wasif Saif
Mostly Streptococcus bovis ( S. bovis ) bacteremia and endocarditis (60%) has been found to be associated with underlying colorectal cancer (CRC). Enterococcus faecalis ( E. faecalis ) bacteremia and endocarditis has no identifiable source in most of the cases. E. faecalis is part of normal gut flora that can translocate through the intestine and cause the systemic infection. With any intestinal lesion or tumor, the barrier is breached and the gut flora like E. faecalis can translocate and cause infection. A 55-years-old male known to have non-ischemic cardiomyopathy with implantation of automated implantable cardioverter defibrillator (AICD) and atrial fibrillation presented with weight loss, fever and back pain...
June 2018: Gastroenterology Research
Yong Tae Hong, Ki Hwan Hong
The non-recurrent inferior laryngeal nerve (NRLN) represents a risk factor for nerve injury during thyroid surgery. The aim of this study is to investigate the traveling patterns of NRLNs and its relationships to inferior thyroid arteries (ITAs). We had 11 patients showing NRLNs on the right side who underwent thyroidectomies. The NRLNs were classified into four different types, according to the traveling patterns. We evaluated the anatomical position of the ITA as follows: (1) three types according to the joint location with the thyroid gland; and (2) three types according to the level of the retro-esophageal subclavian artery (RSA)...
April 2018: Indian Journal of Surgery
Jonny Geber, Niels Hammer
Ossification of the ligamentum flavum of the spine (OLF) is rarely reported in individuals of European ancestry. It has, however, been observed in archaeological skeletons from Europe. The aim of this study was to revisit OLF rates, utilising a mid-nineteenth-century skeletal sample from Ireland. The hypothesis was that the OLF prevalence rate was similar to studies on non-Europeans. Spines from 345 individuals were analysed, and the extent of OLF recorded on the cranial and caudal attachment sites of each vertebra using the following classification system: Grade 0 (no change); Grade 1 (<2 mm); Grade 2 (2-4 mm); Grade 3 (≥4 mm)...
June 18, 2018: Scientific Reports
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