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https://www.readbyqxmd.com/read/29667780/variability-in-vertebral-numbers-does-not-contribute-to-sexual-size-dimorphism-interspecific-variability-or-phenotypic-plasticity-in-body-size-in-geckos-squamata-gekkota-paroedura
#1
Lukáš Kratochvíl, Lukáš Kubička, Martin Vohralík, Zuzana Starostová
Body size is a fundamental trait correlated with nearly every aspect of animal life. It is influenced by numerous genetic and non-genetic factors. Despite its central importance, proximate mechanisms of intra- and interspecific variability in body size are still not well understood even in such a largely studied group as reptiles. For our study, we concentrated on the gecko species Paroedura picta. We investigated whether differences in sexual size dimorphism and in final and asymptotic snout-vent length (induced by a range of incubation and rearing temperatures) are correlated with differences in the number of presacral vertebrae...
April 18, 2018: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29666666/early-factors-associated-with-the-development-of-chronic-pain-in-trauma-patients
#2
Raoul Daoust, Jean Paquet, Lynne Moore, Marcel Émond, Sophie Gosselin, Gilles Lavigne, Manon Choinière, Aline Boulanger, Jean-Marc Mac-Thiong, Jean-Marc Chauny
Objective: To identify factors, available at the time of trauma admission, associated with the development of chronic pain to allow testing of preventive approaches. Methods: In a retrospective observational cohort study, we included all patients ≥ 18 years old admitted for injury in 57 adult trauma centers in the province of Quebec (Canada) between 2004 and 2014. Chronic pain was defined as follows: treated in a chronic pain clinic, diagnosed with chronic pain, or received at least 2 prescriptions of chronic pain medications 3 to 12 months postinjury...
2018: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/29665086/severely-impaired-bone-material-quality-in-chihuahua-zebrafish-resembles-classical-dominant-human-osteogenesis-imperfecta
#3
Imke A K Fiedler, Felix N Schmidt, Eva M Wölfel, Christine Plumeyer, Petar Milovanovic, Roberta Gioia, Francesca Tonelli, Hrishikesh A Bale, Katharina Jähn, Roberta Besio, Antonella Forlino, Björn Busse
Excessive skeletal deformations and brittle fractures in the vast majority of patients suffering from osteogenesis imperfecta (OI) are a result of substantially reduced bone quality. Since the mechanical competence of bone is dependent on the tissue characteristics at small length scales, it is of crucial importance to assess how osteogenesis imperfecta manifests at the micro- and nanoscale of bone. In this context, the Chihuahua (Chi/ +) zebrafish, carrying a heterozygous glycine substitution in the α1 chain of collagen type I, has recently been proposed as suitable animal model of classical dominant OI, showing skeletal deformities, altered mineralization patterns and a smaller body size...
April 17, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29664803/posterior-shoulder-dislocation-associated-with-the-head-splitting-and-humeral-neck-fracture-impact-of-understanding-radiologic-signs-and-experience-with-an-extended-deltopectoral-approach
#4
Kemal Gokkus, Ergin Sagtas, Hasan Kara, Ahmet T Aydin
In this paper, our main objective was to emphasize the competency of extended deltopectoral exposure, enforced with the supraspinatus and subscapularis detachment, to gain access to the entire head. The second important point in this paper was to underline the importance of the knowledge that is necessary for interpreting classic radiologic signs of posterior fracture-dislocation of the shoulder. A 47-year-old woman fell down directly onto her shoulder while she was skiing. She was diagnosed with posterior shoulder dislocation, associated with fracture of the head (head splitting) and humeral neck fracture, with the aid of plain radiographs and computed tomographic results...
April 11, 2018: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/29664450/quantitative-assessment-of-vertebral-artery-anatomy-in-relation-to-cervical-pedicles-surgical-considerations-based-on-regional-differences
#5
Amro Al-Habib, Fahad Albadr, Jehad Ahmed, Abdulrahman Aleissa, Abdullah Al Towim
OBJECTIVE: To quantify the anatomic relationship between the Cervical pedicle screw (CPS), vertebral artery (VA), and related anatomic structures in the Saudi population. METHODS: This retrospective single center study included 50 consecutive patients (35 males) with normal neck findings on computed tomography angiography performed for trauma or vascular evaluation between 2012 and 2014. Radiologic parameters were assessed and correlated with age, weight, height, and body mass index (BMI)...
April 2018: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/29663145/successful-treatment-of-a-diffuse-type-tenosynovial-giant-cell-tumor-in-the-thoracic-spine-mimicking-spinal-metastasis-by-frozen-recapping-laminoplasty-in-a-patient-with-thyroid-cancer
#6
REVIEW
Noritaka Yonezawa, Hideki Murakami, Satoshi Kato, Hiroyuki Hayashi, Hiroyuki Tsuchiya
PURPOSE: Tenosynovial giant cell tumor of the diffuse type (TGCT-D) involving the spine is rare. Its differential diagnosis includes metastatic disease; however, there have been few reports of spinal TGCT-D mimicking spinal metastasis in patients with a history of malignancy. METHODS: We report on a 35-year-old woman with a history of papillary thyroid cancer who was diagnosed with TGCT-D of the thoracic spine mimicking spinal metastasis. Preoperative computed tomography (CT) revealed a 1...
April 16, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29662773/characteristics-of-bone-biochemical-indices-in-predicting-secondary-osteoporotic-fracture-after-intertrochanteric-fracture-in-elderly-women
#7
Shaofeng Yang, Yanan Liu, Qin Shi, Jun Zou, Huilin Yang
Background: This study aimed to explore the characteristics of bone biochemical indices, including bone mineral density (BMD), metabolic markers in elderly women with osteoporotic intertrochanteric fracture and their relevance in secondary fracture. Methods: The standard for follow-up from 58 elderly women was established to analyse the BMD in the injured hip, healthy hip, and the vertebra at 1 week and 12 months after fracture. The serum levels of total procollagen type N-terminal propeptide (tPINP) and the age-related type I cross linked C-telopeptide (β-CTX) were recorded and compared between those patients with and without secondary fractures within 12 months...
January 2018: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29662745/negative-sagittal-balance-following-adult-spinal-deformity-surgery
#8
Robert K Merrill, Jun S Kim, Ian T McNeill, Samuel C Overley, James E Dowdell, John M Caridi, Samuel K Cho
Study Design: Retrospective cohort study. Objective: Elucidate negative sagittal balance following adult spinal deformity surgery. Methods: We conducted a retrospective review of adult spinal deformity patients who underwent long fusion (>5 levels) to the sacrum by a single surgeon at a single institution between 2011 and 2015. Patients were divided into cohorts of postoperative sagittal vertical axis (SVA) <-10 mm, between -10 and +10 mm, or >+10 mm, denoted as groups 1, 2, and 3, respectively...
April 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29662740/low-density-pedicle-screw-constructs-for-adolescent-idiopathic-scoliosis-evaluation-of-effectiveness-and-cost
#9
Oliver O Tannous, Kelly E Banagan, Eric J Belin, Ehsan Jazini, Tristan B Weir, Steven C Ludwig, Daniel E Gelb
Study Design: Retrospective cohort study. Objective: To determine whether a low-density (LD) screw construct can achieve curve correction similar to a high-density (HD) construct in adolescent scoliosis. Methods: Patients treated operatively for idiopathic scoliosis between 2007 and 2011 were identified through a database review. A consistent LD screw construct was used. Radiographic assessment included percent correction of major and fractional lumbar curves, T5-T12 kyphosis, and angle of lowest instrumented vertebra (LIV)...
April 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29662314/pretreatment-of-daily-teriparatide-enhances-the-increase-of-bone-mineral-density-in-cortical-bones-by-denosumab-therapy
#10
Mikio Kamimura, Akira Taguchi, Yukio Nakamura, Hidefumi Koiwai, Shota Ikegami, Shigeharu Uchiyama, Hiroyuki Kato
Background: While it is well known that teriparatide (TPTD) increases bone mineral density (BMD) in osteoporotic patients, it is unknown whether TPTD pretreatment affects BMD after denosumab (DMAb) therapy. Methods: Fifty-seven patients in TPTD-pretreated group and 35 patients in DMAb-alone group had been further analyzed, all of whom were treated by DMAb for 1.5 years. Vitamin D (400 IU) and Ca (600 mg) supplementation was used in all patients. The BMD of lumbar 1-4 vertebrae (L-BMD), bilateral total hips (H-BMD), and bilateral femoral neck (FN-BMD) was quantified at first visit, and at 4, 8, 12, and 18 months after daily TPTD treatment following four times DMAb treatment...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29662230/reliability-and-validity-of-the-new-vikingslice-software-for-computed-tomography-body-composition-analysis
#11
Imanta Ozola-Zālīte, Esben Bolvig Mark, Tomas Gudauskas, Vladimir Lyadov, Søren Schou Olesen, Asbjørn Mohr Drewes, Aldis Pukitis, Jens Brøndum Frokjær
BACKGROUND/OBJECTIVES: Body composition assessment by computed tomography (CT) is increasingly used for diagnostic and prognostic purposes in various patient groups. This study aimed to compare the reliability and validity of a newly in-house developed segmentation software VikingSlice against a commercial software (SliceOMatic) for quantification of adipose tissue and skeletal muscle cross-sectional areas (CSA). SUBJECTS/METHODS: Fifty abdominal CT sets from chronic pancreatitis patients were analyzed (mean age 49, range 27-84 years; 38 males)...
April 16, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29661112/osteoporotic-effect-on-bone-repair-in-lumbar-vertebral-body-defects-in-a-rat-model
#12
Munehiro Sakata, Hitoshi Tonomura, Tomonori Itsuji, Hidenobu Ishibashi, Ryota Takatori, Yasuo Mikami, Masateru Nagae, Ken Ichi Matsuda, Masaki Tanaka, Toshikazu Kubo
INTRODUCTION: The number of patients who suffered from osteoporotic vertebral fractures is increasing. Osteoporosis has been reported to affect the healing process using long bone models. However, few studies have reported using vertebrae. In this study, we created a bone defect in the anterior part of vertebral body in ovariectomized rat and evaluated the healing process. METHODS: Fifty-six 12-week old Sprague Dawley rats were divided into ovariectomy (OVX) and sham operation groups...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29660124/age-and-growth-of-the-endemic-xingu-river-stingray-potamotrygon-leopoldi-validated-using-fluorescent-dyes
#13
P Charvet, F M Santana, K L de Lima, R Lessa
Between 2003 and 2005, vertebrae of 151 Xingu River Potamotrygon leopoldi (Potamotrygonidae) (75 males and 76 females) were analysed to derive a growth curve for this species. The disc width (WD ) was significantly different between sexes, with females measuring 149-700 mm WD and males 109-500 mm WD . The average percentage error for vertebrae readings of the whole sample was 2.7%. The marginal increment ratio (RMI ) showed an increasing trend with the highest value in November, decreasing from December on...
April 16, 2018: Journal of Fish Biology
https://www.readbyqxmd.com/read/29660123/a-new-species-of-hemibrycon-characiformes-characidae-stevardiinae-from-the-upper-magdalena-river-basin-in-colombia
#14
J E García-Melo, J G Albornoz-Garzón, L J García-Melo, F A Villa-Navarro, J A Maldonado-Ocampo
Hemibrycon iqueima sp. nov., is described from small streams in the Magdalena drainage at the foothills of the western slope of the Eastern Cordillera of the Colombian Andes, Suarez municipality, Tolima Department, Colombia. The new species is distinguished from its congeners in the Magdalena-Cauca River basin by a combination of characters related to snout-anal-fin origin length, head length, dorsal-pectoral fin distance, dorsal-fin-hypural distance, postorbital distance, orbital diameter, snout length, number of total vertebrae, pre-dorsal scales, scale rows between anal-fin origin and lateral line, number of branched rays of the anal fin, maxillary teeth number and number and arrangement of hooks on the branched rays of the pectoral and dorsal fins...
April 16, 2018: Journal of Fish Biology
https://www.readbyqxmd.com/read/29659427/opportunistic-bone-density-measurement-on-abdomen-and-pelvis-computed-tomography-to-predict-fracture-risk-in-women-aged-50-to-64-years-without-osteoporosis-risk-factors
#15
Jieming Fang, Andrea Franconeri, Johannes Boos, Jennifer Nimhuircheartaigh, Zheng Zhang, Alexander Brook, Olga R Brook
OBJECTIVE: The aim of this study is to evaluate opportunistic vertebral bone density measurement in abdominal and pelvic computed tomography (CT) to predict future osteoporotic fracture in women aged 50 to 64 years without known osteoporosis risk factors. METHODS: Consecutive female patients 50 to 64 years old without osteoporosis risk factors with 2 CT examinations more than 10 years apart were included. Vertebral height and bone density in each vertebra from T10 to L5 were measured...
April 13, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29658780/inter-and-intraobserver-variability-of-an-anatomical-landmark-based-manual-segmentation-method-by-mri-for-the-assessment-of-skeletal-muscle-fat-content-and-area-in-subjects-from-the-general-population
#16
Lena Sophie Kiefer, Jana Fabian, Roberto Lorbeer, Jürgen Machann, Corinna Storz, Mareen Sarah Kraus, Elke Wintermeyer, Christopher L Schlett, Frank Roemer, Konstantin Nikolaou, Annette Peters, Fabian Bamberg
OBJECTIVES: Changes in skeletal muscle composition, such as fat content and mass, may exert unique metabolic and musculoskeletal risks; however, the reproducibility of their assessment is unknown. We determined the variability of the assessment of skeletal muscle fat content and area by magnetic resonance imaging (MRI) in a population-based sample. METHODS: A random sample from a prospective, community-based cohort study (KORA-FF4) was included. Skeletal muscle fat content was quantified as proton-density fat-fraction (PDFF) and area as cross-sectional area (CSA) in multi-echo Dixon sequences (TR 8...
April 16, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29658659/-effect-of-resveratrol-on-peak-bone-mass-in-growing-rats
#17
Huirong Xi, Yuhai Gao, Fangfang Yang, Wenyuan Li, Huiping Ma, Keming Chen
<b>Objective:</b> To investigate the effect of resveratrol on peak bone mineral density and bone mass in growing rats. <b>Methods:</b> Thirty-six female healthy Wistar rats were randomly divided into control group, icariin group and resveratrol group with 12 rats in each group. Icariin (25 mg·kg<sup>-1</sup>·d<sup>-1</sup>), resveratrol (8.4 mg·kg<sup>-1</sup>·d<sup>-1</sup>) or equal volume of distilled water were given by gavage to icariin group, resveratrol group and control group, respectively...
May 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/29655516/plga-%C3%AE-tcp-composite-scaffold-incorporating-salvianolic-acid-b-promotes-bone-fusion-by-angiogenesis-and-osteogenesis-in-a-rat-spinal-fusion-model
#18
Sien Lin, Liao Cui, Guanghua Chen, Jianping Huang, Yanhua Yang, Kaijie Zou, Yuxiao Lai, Xinluan Wang, Liyi Zou, Tie Wu, Jack Chun Yiu Cheng, Gang Li, Bo Wei, Wayne Yuk Wai Lee
Spinal disorders often require surgical treatment called spinal fusion to restore a stabilized spine where bone grafts are implanted for the fusion of adjacent vertebras. In this study, we developed a bioactive composite scaffold incorporated with salvianolic acid B (SB), an active component extracted from Danshen. This study aimed to evaluate the effects of SB-incorporated porous scaffold on spinal fusion models. The composite scaffolds composed of poly (lactic-co-glycolic acid) and tricalcium phosphate (PLGA/β-TCP) were fabricated with low-temperature rapid prototyping technique, which incorporated SB at low (SB-L), middle (SB-M), high (SB-H) doses, and pure PLGA/β-TCP as blank control (Con)...
April 4, 2018: Biomaterials
https://www.readbyqxmd.com/read/29653020/developmental-toxicity-of-flucytosine-following-administration-to-pregnant-rats-at-a-specific-time-point-of-organogenesis
#19
Sakiko Fujii, Kaoru Yabe, Yuki Kariwano-Kimura, Masatoshi Furukawa, Kouta Itoh, Masao Matsuura, Masao Horimoto
To investigate the abnormalities that are specific to administration of flucytosine at one time point during embryonic organogenesis, flucytosine was administered orally to pregnant SD rats in a single dose on day 11 of pregnancy at 25 or 35 mg/kg. Fetuses on day 20 of pregnancy were externally, viscerally and skeletally examined. Maternal body weight gain and food consumption were suppressed the day after administration of a 35 mg/kg. Fetal examinations revealed various alterations in both dose groups: externally preaxial polydactyly in the hind limb; skeletally fused lumbar centrum, absent sacral centrum, supernumerary sacral vertebra, and absent ribs...
April 13, 2018: Congenital Anomalies
https://www.readbyqxmd.com/read/29652238/challenge-of-handling-a-charcot-spinal-arthropathy-with-a-novel-hybrid-fibular-autograft-and-expandable-cage
#20
Nissim Ohana, Daniel Benharroch, Dimitri Sheinis
A 26-year-old man, who was paraplegic for 6 years due to a motor vehicle accident, presented to the authors' clinic following his incapacity to withstand a sitting posture, the frequent sensation of "clicks" in his back, and a complaint of back pain while in his wheelchair. On imaging, his dorsal spine showed a complete arthrodesis of the primarily fused vertebrae. However, distal to this segment, a Charcot spinal arthropathy with subluxation of T12-L1 was evident. Repair of this complex, uncommon, late complication of his paraplegia by the frequently used fusion techniques was shown to be inappropriate...
April 13, 2018: Journal of Neurosurgery. Spine
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