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https://www.readbyqxmd.com/read/28430086/genotypic-relatedness-and-antimicrobial-resistance-of-salmonella-heidelberg-isolated-from-chickens-and-turkeys-in-the-midwestern-united-states
#1
Muhammad Nisar, Issmat I Kassem, Gireesh Rajashekara, Sagar M Goyal, Dale Lauer, Shauna Voss, Kakambi V Nagaraja
Salmonella is one of the most common causes of foodborne illnesses in humans in the United States, and domestic poultry is considered an important source of this pathogen. Salmonella enterica subsp. enterica serovar Heidelberg is the fourth most commonly reported Salmonella from retail meats and food animals in the United States. We assessed the genotypes and antimicrobial resistance phenotypes of Salmonella Heidelberg isolated from various chicken and turkey hatcheries and breeder farms in the Midwest. The genotypes of 33 S...
May 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28429837/fluorescence-based-sensor-for-selective-and-sensitive-detection-of-amoxicillin-amox-in-aqueous-medium-application-to-pharmaceutical-and-biomedical-analysis
#2
Samadhan P Pawar, Laxman S Walekar, Dattatray B Gunjal, Dattatray K Dalavi, Anil H Gore, Prashant V Anbhule, Shivajirao R Patil, Govind B Kolekar
We here for the first time demonstrate an analytical approach for the highly selective and sensitive detection of amoxicillin (Amox) in aqueous medium based on the fluorescence quenching of quantum dots (QDs). The change in fluorescence intensity of mercaptopropionic acid-capped cadmium sulphide (MPA-CdS) QDs is attributed to the increasing concentration of Amox. The results show that the fluorescence quenching of QDs by Amox takes place through both static and dynamic types of quenching mechanism. The fluorescence quenching of QDs with increase in concentration of Amox shows the linear range between 5 μg ml(-1) and 30 μg ml(-1) and the limit of detection (LOD) is 5...
April 21, 2017: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/28429163/antimicrobial-susceptibility-of-bacterial-isolates-from-patients-presenting-with-ear-nose-and-throat-ent-infections-in-the-german-community-healthcare-setting
#3
B Olzowy, M Kresken, M Havel, D Hafner, B Körber-Irrgang
Empiric initial antibiotic therapy of bacterial infections is based primarily upon the susceptibility of the most common causative pathogens. The purpose of this study was to provide susceptibility data on six bacterial species known to cause ear, nose and throat (ENT) infections. A total of 1066 isolates collected during a nationwide laboratory-based surveillance study were analysed. All Streptococcus pyogenes isolates were penicillin (PEN)-susceptible, indicating that natural penicillins can still be recommended as the first-line treatment for group A streptococcal tonsillopharyngitis...
April 20, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28427354/unique-case-report-of-a-chromomycosis-and-listeria-in-soft-tissue-and-cerebellar-abscesses-after-kidney-transplantation
#4
J Tourret, N Benabdellah, S Drouin, F Charlotte, J Rottembourg, N Arzouk, A Fekkar, B Barrou
BACKGROUND: Chromomycosis is a rare mycotic infection encountered in tropical and subtropical regions. The disease presents as a slowly-evolving nodule that can become infected with bacteria. Here, we describe a unique association of abscesses caused by a chromomycosis and Listeria monocytogenes in a kidney transplant recipient, and didactically expose how the appropriate diagnosis was reached. CASE PRESENTATION: A 49-year old male originating from the Caribbean presented a scalp lesion which was surgically removed in his hometown where it was misdiagnosed as a sporotrichosis on histology, 3 years after he received a kidney transplant...
April 20, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28426744/pharmacokinetics-and-relative-bioavailability-of-an-oral-amoxicillin-apramycin-combination-in-pigs
#5
Chongshan Dai, Tingting Zhao, Xing Yang, Xilong Xiao, Tony Velkov, Shusheng Tang
A new compound granular premix of amoxicillin (20% w/w dry mass)/apramycin (5% w/w dry mass) was developed, and its pharmacokinetics and relative bioavailability were determined in pigs following oral administration following a cross-over study design. The pharmacokinetic parameters of amoxicillin (t1/2λ = 6.43 ± 4.85h, Cmax = 3.2 ± 1.35 μg·mL-1, Tmax = 1.92 ± 0.58, AUCINF = 8.98 ± 2.11 h·μg·mL-1) and apramycin (t1/2λ = 8.67±4.4h, Cmax = 0.23 ± 0.12 μg·mL-1, Tmax = 2.25 ± 0.82 h, AUCINF = 12...
2017: PloS One
https://www.readbyqxmd.com/read/28420680/use-of-azithromycin-and-risk-of-ventricular-arrhythmia
#6
Gianluca Trifirò, Maria de Ridder, Janet Sultana, Alessandro Oteri, Peter Rijnbeek, Serena Pecchioli, Giampiero Mazzaglia, Irene Bezemer, Edeltraut Garbe, Tania Schink, Elisabetta Poluzzi, Trine Frøslev, Mariam Molokhia, Igor Diemberger, Miriam C J M Sturkenboom
BACKGROUND: There are conflicting findings from observational studies of the arrhythrogenic potential of azithromycin. Our aim was to quantify the association between azithromycin use and the risk of ventricular arrhythmia. METHODS: We conducted a nested case-control study within a cohort of new antibiotic users identified from a network of 7 population-based health care databases in Denmark, Germany, Italy, the Netherlands and the United Kingdom for the period 1997-2010...
April 18, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28419126/availability-and-affordability-of-antimalarial-and-antibiotic-medicines-in-malawi
#7
Felix Khuluza, Lutz Heide
BACKGROUND: Availability and affordability of medicines are key determinants of universal health coverage, yet achieving them presents a major challenge especially in low-income countries. We here present an analysis of availability and prices of antimalarial and antibiotic medicines in public, faith-based and private health facilities in Malawi. Medicines are provided free of charge in the public health care system of Malawi. In contrast, facilities of the Christian Health Association of Malawi (CHAM) usually charge their patients for medicines, as do private for-profit facilities...
2017: PloS One
https://www.readbyqxmd.com/read/28418316/amoxicillin-and-ceftriaxone-as-treatment-alternatives-to-penicillin-for-maternal-syphilis
#8
Yuichi Katanami, Takehiro Hashimoto, Saho Takaya, Kei Yamamoto, Satoshi Kutsuna, Nozomi Takeshita, Kayoko Hayakawa, Shuzo Kanagawa, Norio Ohmagari
There is no proven alternative to penicillin for treatment of maternal syphilis. We report 2 case-patients with maternal syphilis who were successfully treated without penicillin. We used amoxicillin and probenecid for the first case-patient and amoxicillin, probenecid, and ceftriaxone for the second case-patient.
May 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28417452/worldwide-pattern-of-antibiotic-prescription-in-endodontic-infections
#9
REVIEW
Juan José Segura-Egea, Jenifer Martín-González, María Del Carmen Jiménez-Sánchez, Isabel Crespo-Gallardo, Juan José Saúco-Márquez, Eugenio Velasco-Ortega
BACKGROUND: Odontogenic infections, and especially endodontic infections, are polymicrobial, involving a combination of Gram-positive and Gram-negative facultative anaerobes and strictly anaerobic bacteria. Therefore, antibiotics can be used as an adjunct to endodontic treatment. However, most chronic and even acute endodontic infections can be successfully managed by disinfection of the root-canal system, which eliminates the source of infection, followed by abscess drainage or tooth extraction, without the need for antibiotics...
April 17, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28415489/design-of-salecan-containing-semi-ipn-hydrogel-for-amoxicillin-delivery
#10
Xiaoliang Qi, Wei Wei, Junjian Li, Ting Su, Xihao Pan, Gancheng Zuo, Jianfa Zhang, Wei Dong
Salecan is a new linear extracellular β-glucan. The unique structure and beneficial properties of Salecan makes it an appealing material in biomedical applications. In this work, novel drug devices based on Salecan in a hydrogel matrix of poly(N-(3-dimethylaminopropyl)acrylamide-co-acrylamide) (Salecan/PDA) were fabricated via free radical polymerization for controlled release of amoxicillin. It was demonstrated that amoxicillin was efficiently encapsulated into the developed hydrogels and released in a Salecan dose-dependent and pH-sensitive manner...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28414107/antimicrobial-susceptibility-of-bacteroides-fragilis-group-organisms-in-hong-kong-by-the-tentative-eucast-disc-diffusion-method
#11
Pak-Leung Ho, Chong-Yee Yau, Lok-Yan Ho, Eileen Ling-Yi Lai, Melissa Chun-Jiao Liu, Cindy Wing-Sze Tse, Kin-Hung Chow
This study used a recently developed EUCAST disc diffusion method to measure the susceptibility of 741 B. fragilis group isolates to six antibiotics. Isolates nonsusceptible to imipenem and metronidazole by the disc method were further investigated by E-test. Species identification was obtained by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS), PCR assays and 16S rRNA sequencing. The most common species were B. fragilis (n = 424, including 81 division II and 343 division I isolates), B...
April 14, 2017: Anaerobe
https://www.readbyqxmd.com/read/28413565/enrichment-of-in-vivo-transcription-data-from-dietary-intervention-studies-with-in-vitro-data-provides-improved-insight-into-gene-regulation-mechanisms-in-the-intestinal-mucosa
#12
Marcel Hulst, Alfons Jansman, Ilonka Wijers, Arjan Hoekman, Stéphanie Vastenhouw, Marinus van Krimpen, Mari Smits, Dirkjan Schokker
BACKGROUND: Gene expression profiles of intestinal mucosa of chickens and pigs fed over long-term periods (days/weeks) with a diet rich in rye and a diet supplemented with zinc, respectively, or of chickens after a one-day amoxicillin treatment of chickens, were recorded recently. Such dietary interventions are frequently used to modulate animal performance or therapeutically for monogastric livestock. In this study, changes in gene expression induced by these three interventions in cultured "Intestinal Porcine Epithelial Cells" (IPEC-J2) recorded after a short-term period of 2 and 6 hours, were compared to the in vivo gene expression profiles in order to evaluate the capability of this in vitro bioassay in predicting in vivo responses...
2017: Genes & Nutrition
https://www.readbyqxmd.com/read/28412931/prevalence-of-escherichia-coli-o157-h7-in-beef-cattle-at-slaughter-and-beef-carcasses-at-retail-shops-in-ethiopia
#13
Rosa Abdissa, Woynshet Haile, Akafete Teklu Fite, Ashenafi Feyisa Beyi, Getahun E Agga, Bedaso Mammo Edao, Fanos Tadesse, Mesula Geloye Korsa, Takele Beyene, Tariku Jibat Beyene, Lieven De Zutter, Eric Cox, Bruno Maria Goddeeris
BACKGROUND: There is paucity of information regarding the epidemiology of Escherichia coli O157: H7 in developing countries. In this study, we investigated the occurrence of E. coli O157: H7 associated with beef cattle at processing plants and at retail shops in Ethiopia. METHODS: Various samples were collected from beef cattle at slaughter/processing plants, carcass at retail shops and humans at health centers. E. coli O157: H7 was isolated, identified and characterized for antimicrobial resistance, using standard microbiological methods...
April 17, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28412864/cutaneous-allergic-drug-reactions-update-on-pathophysiology-diagnostic-procedures-and-differential-diagnostic
#14
Galina Balakirski, Hans F Merk
Important changes in the understanding and management of drug hypersensitivity reactions during the last years result from the increasing importance of biologics in medical practice, which differ in their spectrum of adverse drug reactions (ADRs) from the classical covalent drugs. With regard to covalent drugs, ampicillin and amoxicillin as well as clavulanic acid play an increasing role among ADRs to betalactam antibiotics. Fluoroquinolones are mainly the cause of anaphylactic and photosensitivity reactions...
April 17, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28410941/potentiometric-uv-and-1-h-nmr-study-on-the-interaction-of-cu-2-with-ampicillin-and-amoxicillin-in-aqueous-solution
#15
Paola Cardiano, Francesco Crea, Claudia Foti, Ottavia Giuffrè, Silvio Sammartano
A potentiometric, UV and (1)H NMR study on Cu(2+)-ampicillin [(2S,5R,6R)-6-([(2R)-2-amino-2-phenylacetyl]amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid] and -amoxicillin [(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)-acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-24-carboxylic acid] systems in NaCl aqueous solution at I=0.15molL(-1) and t=25°C is reported. On the basis of potentiometric results two speciation models were proposed for each system. It was found that spectrophotometric and (1)H NMR measurements are essential for selecting the most reliable speciation models...
April 4, 2017: Biophysical Chemistry
https://www.readbyqxmd.com/read/28409589/if-you-give-amoxicillin-clavulanate-to-six-to-23-month-olds-with-aom-10-days-is-preferable-to-five-days
#16
Mark H Ebell
No abstract text is available yet for this article.
April 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28407007/polaprezinc-combined-with-clarithromycin-based-triple-therapy-for-helicobacter-pylori-associated-gastritis-a-prospective-multicenter-randomized-clinical-trial
#17
RANDOMIZED CONTROLLED TRIAL
Bei Tan, Han-Qing Luo, Hong Xu, Nong-Hua Lv, Rui-Hua Shi, He-Sheng Luo, Jian-Sheng Li, Jian-Lin Ren, Yi-You Zou, Yan-Qing Li, Feng Ji, Jing-Yuan Fang, Jia-Ming Qian
The efficacy and safety of polaprezinc combined with triple therapy was compared with triple therapy alone in the eradication of Helicobacter pylori. A randomized, parallel-group, open-label, controlled, prospective multicenter study was conducted in 11 cities in China. Treatment-naive patients with H. pylori-associated gastritis were randomly assigned to one of three arms for a 14-day treatment: Arm A triple therapy (omeprazole 20 mg, amoxicillin 1 g, and clarithromycin 500 mg, each twice daily) plus polaprezinc 75 mg twice daily; Arm B triple therapy plus polaprezinc 150 mg twice daily, or Arm C triple therapy alone...
2017: PloS One
https://www.readbyqxmd.com/read/28403365/crown-discoloration-promoted-by-materials-used-in-regenerative-endodontic-procedures-and-effect-of-dental-bleaching-spectrophotometric-analysis
#18
Luciane Geanini Pena Dos Santos, Wilson Tadeu Felippe, Beatriz Dulcineia Mendes de Souza, Andrea Cristina Konrath, Mabel Mariela Rodríguez Cordeiro, Mara Cristina Santos Felippe
Objectives: To assess tooth crown's color after intracanal treatment with triple antibiotic paste (TAP) or calcium hydroxide (CH); cervical sealing with glass ionomer cement (GIC) or mineral trioxide aggregate (MTA); and bleaching with carbamide peroxide. Material and Methods: After pulp removal and color spectrophotometer measurement, 50 bovine incisors were divided into 4 experimental groups and one control (untreated). Experiments were performed in phases (Ph)...
March 2017: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28402300/studies-on-the-adsorption-of-amoxicillin-on-multi-wall-carbon-nanotubes
#19
Davoud Balarak, FerdosKord Mostafapour, Edris Bazrafshan, Tawfik A Saleh
This study examined the feasibility of removing amoxicillin (AMO) from aqueous solutions using multi-wall carbon nanotubes. The equilibrium adsorption data were analyzed using four widely applied isotherms: Langmuir, Freundlich, Temkin, and Dubinin-Radushkevich. The results showed that the Langmuir isotherm model fits well the obtained experimental data. The adsorption process followed the pseudo-second-order model. The activation energy was found to be 19 kJ/mol. The Standard free energy changes, ΔG(0), values were negative; the standard enthalpy change (ΔH(0)), and standard entropy change (ΔS(0)) values of the process were 4 kJ/mol and 36 J/mol...
April 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28400887/antibiotic-prophylaxis-in-orbital-fractures
#20
Benjamin Reiss, Lamise Rajjoub, Tamer Mansour, Tony Chen, Aisha Mumtaz
PURPOSE: To determine whether prophylactic antibiotic use in patients with orbital fracture prevent orbital infection. DESIGN: Retrospective cohort study. PARTICIPANTS: All patients diagnosed with orbital fracture between January 1, 2008 and March 1, 2014 at The George Washington University Hospital and Clinics. MAIN OUTCOME MEASURES: Development of orbital infection. RESULTS: One hundred seventy-two patients with orbital fracture met our inclusion and exclusion criteria...
2017: Open Ophthalmology Journal
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