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Chronic fatigue treatment

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https://www.readbyqxmd.com/read/29133662/a-tiny-tick-can-cause-a-big-health-problem
#1
Manuel John, M Raman, Keith Ryan
Ticks are tiny crawling bugs in the spider family that feed by sucking blood from animals. They are second only to mosquitoes as vectors of human disease, both infectious and toxic. Infected ticks spread over a hundred diseases, some of which are fatal if undetected. They spread the spirochete (which multiplies in the insect's gut) with a subsequent bite to the next host. We describe the only reported cases of peri ocular tick bite from India that presented to us within a span of 3 days and its management. Due suspicion and magnification of the lesions revealed the ticks which otherwise masqueraded as small skin tags/moles on gross examination...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29133321/can-physical-assessment-techniques-aid-diagnosis-in-people-with-chronic-fatigue-syndrome-myalgic-encephalomyelitis-a-diagnostic-accuracy-study
#2
Lucy Hives, Alice Bradley, Jim Richards, Chris Sutton, James Selfe, Bhaskar Basu, Kerry Maguire, Gail Sumner, Tarek Gaber, Annice Mukherjee, Raymond N Perrin
OBJECTIVE: To assess five physical signs to see whether they can assist in the screening of patients with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and potentially lead to quicker treatment. METHODS: This was a diagnostic accuracy study with inter-rater agreement assessment. Participants recruited from two National Health Service hospitals, local CFS/ME support groups and the community were examined by three practitioners on the same day in a randomised order...
November 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/29125079/-relapse-of-chronic-inflammatory-demyelinating-polyneuropathy-following-treatment-with-zoledronic-acid
#3
M Loef, E C T Geijteman, K J Beelen, M Bornebroek, D H Schweitzer
BACKGROUND: Zoledronic acid is a nitrogen-containing bisphosphonate that is frequently used in the treatment of osteoporosis. Many patients experience a so-called acute-phase reaction during initial treatment; this is characterized by flu-like symptoms and fever. CASE DESCRIPTION: We describe a 61-year-old woman who suffered from chronic inflammatory demyelinating polyneuropathy (CIDP), and who was started on intravenous zoledronic acid treatment as adjuvant therapy for breast cancer...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29121889/prevalence-and-associated-factors-of-medication-non-adherence-in-hematological-oncological-patients-in-their-home-situation
#4
Linda Bouwman, Corien M Eeltink, Otto Visser, Jeroen J W M Janssen, Jolanda M Maaskant
BACKGROUND: Medication non-adherence is associated with poor health outcomes and increased health care costs. Depending on definitions, reported non-adherence rates in cancer patients ranges between 16 and 100%, which illustrates a serious problem. In malignancy, non-adherence reduces chances of achievement of treatment response and may thereby lead to progression or even relapse. Except for Chronic Myeloid Leukemia (CML), the extent of non-adherence has not been investigated in hematological-oncological patients in an outpatient setting...
November 9, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29115151/sofosbuvir-velpatasvir-voxilaprevir-a-pan-genotypic-direct-acting-antiviral-combination-for-hepatitis-c
#5
Elias B Chahine, Denise Kelley, Lindsey M Childs-Kean
OBJECTIVES: To review the efficacy and safety of sofosbuvir/velpatasvir/voxilaprevir in the treatment of hepatitis C virus (HCV) infection. DATA SOURCES: A literature search through PubMed was conducted (August 2010 to August 2017) using the terms GS-9857, voxilaprevir, and NS3/4A protease inhibitor. STUDY SELECTION/DATA EXTRACTION: Studies of sofosbuvir/velpatasvir/voxilaprevir were identified. DATA SYNTHESIS: Sofosbuvir/velpatasvir/voxilaprevir is indicated for adult patients with chronic HCV without cirrhosis or with compensated cirrhosis who have (1) genotype 1 through 6 and have previously been treated with an NS5A inhibitor or (2) genotype 1a or 3 and have previously been treated with sofosbuvir without an NS5A inhibitor...
November 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29104961/a-comparison-of-case-definitions-for-myalgic-encephalomyelitis-and-chronic-fatigue-syndrome
#6
Madison Sunnquist, Leonard A Jason, Pamela Nehrke, Ellen M Goudsmit
Many professionals have described the clinical presentation of myalgic encephalomyelitis (ME), but recent efforts have focused on the development of ME criteria that can be reliably applied. The current study compared the symptoms and functioning of individuals who met the newly-developed Institute of Medicine (IOM) clinical criteria to a revised version of the London criteria for ME. While 76% of a sample diagnosed with chronic fatigue syndrome (CFS) met the IOM criteria, 44% met the revised London criteria...
2017: J Chronic Dis Manag
https://www.readbyqxmd.com/read/29102461/effect-of-swarna-jibanti-coelogyne-cristata-lindley-in-alleviation-of-chronic-fatigue-syndrome-in-aged-wistar-rats
#7
Achintya Mitra, Tapas Kumar Sur, Sachhidananda Upadhyay, Dipankar Bhattacharyya, Jayram Hazra
BACKGROUND: Swarna Jibanti scientifically known as Coelogyne cristata Lindley (Orchidaceae), an orchid mentioned in Ayurvedic medicine is used to promote healthy life span. OBJECTIVE: The present work was planned to study the efficacy of hydro-alcoholic extract of pseudobulbs of C.cristata (CCE) to assess its role on chronic fatigue syndrome (CFS) induced behavioural and biochemical changes in aged Wistar rats compared to Panax ginseng (PG), a prototype anti-stress agent...
November 1, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29096528/the-presence-of-co-morbid-mental-health-problems-in-a-cohort-of-adolescents-with-chronic-fatigue-syndrome
#8
Maria Elizabeth Loades, Katharine A Rimes, Sheila Ali, Kate Lievesley, Trudie Chalder
OBJECTIVE: To report on the prevalence of mental health disorders in adolescents with chronic fatigue syndrome (CFS) and to compare the diagnoses identified by a brief clinician-administered psychiatric interview with self-report screening questionnaires. DESIGN: Cross-sectional study. SETTING: Consecutive attenders to specialist CFS clinics in the United Kingdom. PATIENTS: N = 52 adolescents, age 12-18 years with CFS...
October 1, 2017: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/29094875/heart-failure-with-preserved-ejection-fraction-diagnosis-and-management
#9
John D Gazewood, Patrick L Turner
Heart failure with preserved ejection fraction, also referred to as diastolic heart failure, causes almost one-half of the 5 million cases of heart failure in the United States. It is more common among older patients and women, and results from abnormalities of active ventricular relaxation and passive ventricular compliance, leading to a decline in stroke volume and cardiac output. Heart failure with preserved ejection fraction should be suspected in patients with typical symptoms (e.g., fatigue, weakness, dyspnea, orthopnea, paroxysmal nocturnal dyspnea, edema) and signs (S3 heart sound, displaced apical pulse, and jugular venous distension) of chronic heart failure...
November 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/29094622/long-term-effects-of-internet-supported-cognitive-behaviour-therapy
#10
Gerhard Andersson, Alexander Rozental, Roz Shafran, Per Carlbring
Internet-supported and therapist-guided cognitive behaviour therapy (ICBT) is effective for a range of problems in the short run, but less is known about the long-term effects with follow-ups of two years or longer. Areas covered: This paper reviews studies in which the long-term effects of guided ICBT were investigated. Following literature searches in PubMed and other sources meta-analytic statistics were calculated for 14 studies involving a total of 902 participants, and an average follow-up period of three years...
November 2, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/29091342/ledipasvir-sofosbuvir-for-treatment-of-hepatitis-c-virus-in-sofosbuvir-experienced-ns5a-treatment-naive-patients-findings-from-two-randomized-trials
#11
Edward Tam, Anne F Luetkemeyer, Parvez S Mantry, Sanjaya K Satapathy, Peter Ghali, Minhee Kang, Richard Haubrich, Xianlin Shen, Liyun Ni, Gregory Camus, Amanda Copans, Lorenzo Rossaro, Bill Guyer, Robert S Brown
BACKGROUND & AIMS: We report data from two similarly designed studies that evaluated the efficacy, safety, and optimal duration of ledipasvir/sofosbuvir (LDV/SOF) ± ribavirin (RBV) for retreatment of chronic hepatitis C virus (HCV) in individuals who failed to achieve sustained virologic response (SVR) with prior SOF-based, non-NS5A inhibitor-containing regimens. METHODS: The RESCUE study enrolled HCV mono-infected adults with genotype 1 or 4. Non-cirrhotic participants were randomized to 12 weeks of LDV/SOF or LDV/SOF+RBV...
November 1, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29084357/adverse-events-associated-with-medium-and-long-term-use-of-opioids-for-chronic-non-cancer-pain-an-overview-of-cochrane-reviews
#12
REVIEW
Charl Els, Tanya D Jackson, Diane Kunyk, Vernon G Lappi, Barend Sonnenberg, Reidar Hagtvedt, Sangita Sharma, Fariba Kolahdooz, Sebastian Straube
BACKGROUND: Chronic pain is common and can be challenging to manage. Despite increased utilisation of opioids, the safety and efficacy of long-term use of these compounds for chronic non-cancer pain (CNCP) remains controversial. This overview of Cochrane Reviews complements the overview entitled 'High-dose opioids for chronic non-cancer pain: an overview of Cochrane Reviews'. OBJECTIVES: To provide an overview of the occurrence and nature of adverse events associated with any opioid agent (any dose, frequency, or route of administration) used on a medium- or long-term basis for the treatment of CNCP in adults...
October 30, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29079938/adverse-effects-of-direct-acting-antiviral-based-regimens-in-chronic-hepatitis-c-patients-a-brazilian-experience
#13
Thalia Medeiros, Camila de Morais Salviato, Natalia Fonseca do Rosário, Geórgia do Nascimento Saraiva, Eliane Bordalo Cathalá Esberard, Jorge Reis Almeida, Analúcia Rampazzo Xavier, Andrea Alice da Silva
Background Direct-acting antivirals (DAA) are currently used for the treatment of chronic hepatitis C (HCV). However, few studies describe the adverse effects (AE) associated with DAA therapy in "real-word" cohorts. Aim To evaluate AE in Brazilian chronic HCV patients after DAA-therapy. Setting A reference center for hepatitis treatment in Rio de Janeiro, Brazil. Methods An observational "real-world" study was conducted with 102 chronic HCV patients undergoing DAA therapy for 12 or 24 weeks. The self-reported AE were correlated with cirrhosis status, genotype, age, current therapeutic schemes and comorbidities...
October 27, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29079869/-new-aspects-of-symptomatic-ms-treatment-part%C3%A2-5-fatigue
#14
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) is nowadays of similar importance as immunotherapy within a comprehensive treatment concept of this chronic disease. It makes a considerable contribution to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of the quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Clinical Competence Network Multiple Sclerosis (Klinisches Kompetenznetz Multiple Sklerose, KKN-MS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation have taken place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29079868/-new-aspects-of-symptomatic-ms-treatment-part%C3%A2-6-cognitive-dysfunction-and-rehabilitation
#15
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) is nowadays of similar importance as immunotherapy within a comprehensive treatment concept of this chronic disease. It makes a considerable contribution to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of the quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Clinical Competence Network Multiple Sclerosis ("Klinisches Kompetenznetz Multiple Sklerose", KKN-MS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation have taken place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29079866/-new-aspects-of-symptomatic-ms-treatment-part%C3%A2-4-sexual-dysfunction-and-eye-movement-disorders
#16
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) is nowadays of similar importance as immunotherapy within a comprehensive treatment concept of this chronic disease. It makes a considerable contribution to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of the quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Clinical Competence Network Multiple Sclerosis (Klinisches Kompetenznetz Multiple Sklerose, KKNMS) in 2014, several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation have taken place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29079865/-what-is-new-in-symptomatic-ms-treatment-part%C3%A2-3-bladder-dysfunction
#17
REVIEW
T Henze, W Feneberg, P Flachenecker, D Seidel, H Albrecht, M Starck, S G Meuth
The symptomatic treatment of multiple sclerosis (MS) nowadays is of similar importance as immunotherapy within a comprehensive concept of therapy of this chronic disease, since it contributes considerably to the reduction of disabilities in activities of daily living as well as social and occupational life. Moreover, symptomatic treatment is of great importance for amelioration of quality of life. Since our last survey of symptomatic MS treatment in 2004 and publication of the guidelines of the German Neurological Society and the Klinisches Kompetenznetz Multiple Sklerose (KKNMS) in 2014 several developments within the topics of mobility, bladder and sexual function, vision, fatigue, cognition and rehabilitation took place...
October 27, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/29077623/internet-based-exposure-therapy-for-fibromyalgia-a-randomized-controlled-trial
#18
Maria Hedman-Lagerlöf, Erik Hedman-Lagerlöf, Erland Axelsson, Brjánn Ljótsson, Johanna Engelbrektsson, Sofia Hultkrantz, Karolina Lundbäck, Daniel Björkander, Rikard Wicksell, Ida Flink, Erik Andersson
Fibromyalgia (FM) is a common and disabling chronic pain disorder, for which existing pharmacological and psychological treatments have yet yielded insufficient effects. Previous literature has shown that exposure therapy may be an effective treatment for chronic pain. This study constitutes the first randomized controlled trial evaluating exposure therapy for FM. One hundred and forty participants with diagnosed FM were randomized to a 10-week internet-based exposure treatment (iExp; n=70) or a waitlist control condition (WLC; n=70)...
October 26, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29075139/a-structured-group-exercise-program-for-patients-with-metastatic-cancer-receiving-chemotherapy-and-ctnnb1-%C3%AE-catenin-as-a-biomarker-of-exercise-efficacy
#19
James A Chiarotto, Riyad Akbarali, Lara Bellotti, George Dranitsaris
INTRODUCTION: Exercise can improve the symptoms of cancer. However, is it a cancer treatment? We tested the feasibility of group exercise for metastatic cancer patients while on chemotherapy. A biomarker for exercise efficacy in colorectal cancer (CRC), β-catenin, was tested. METHODS: Patients undergoing palliative chemotherapy were eligible for a pre-post, single-arm study comprising an indefinite, weekly group exercise intervention using strength and aerobic training...
2017: Cancer Management and Research
https://www.readbyqxmd.com/read/29071982/-effect-of-acupuncture-on-the-expression-of-transcription-factor-t-bet-gata-3-in-plasma-of-rats-with-chronic-fatigue-syndrome
#20
Xiang-Yi Wang, Chang-Zheng Liu, Bo Lei
OBJECTIVE: To observe the effect of acupuncture on the expression of T-box expressed in T cell (T-bet)/GATA binding factor-3 (GATA-3) in plasma of rats with chronic fatigue syndrome (CFS) and explore the mechanism of acupuncture treatment for CFS. METHODS: Forty-eight healthy male SD rats were randomly divided into blank control group, CFS model group, acupuncture group, and ginsenoside group (12 rats in each group). CFS rat model was established by combining restriction and cold water swimming...
June 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
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