Takayuki Warisawa, Christopher M Cook, Yousif Ahmad, James P Howard, Henry Seligman, Christopher Rajkumar, Takumi Toya, Shunichi Doi, Akihiro Nakajima, Masafumi Nakayama, Rafael Vera-Urquiza, Sonoka Yuasa, Takao Sato, Yuetsu Kikuta, Yoshiaki Kawase, Hidetaka Nishina, Rasha Al-Lamee, Sayan Sen, Amir Lerman, Hitoshi Matsuo, Yoshihiro J Akashi, Javier Escaned, Justin E Davies
Despite guideline-based recommendation of the interchangeable use of instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR) to guide revascularization decision-making, iFR/FFR could demonstrate different physiological or clinical outcomes in some specific patient or lesion subsets. Therefore, we sought to investigate the impact of difference between iFR and FFR-guided revascularization decision-making on clinical outcomes in patients with left main disease (LMD). In this international multicenter registry of LMD with physiological interrogation, we identified 275 patients in whom physiological assessment was performed with both iFR/FFR...
April 20, 2024: Cardiovascular Intervention and Therapeutics