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Trends in anatomy research

Zengling Yang, Jiaqi Mei, Zhiqiang Liu, Guangqun Huang, Guan Huang, Lujia Han
Understanding the biochemical heterogeneity of plant tissue linked to crop straw anatomy is attractive to plant researchers and researchers in the field of biomass-refinery. This study provides an in-situ analysis and semi-quantitative, visualization distributions of major composition distribution in internodal transverse sections of wheat straw based on FTIR microspec-troscopic imaging, with a fast Non-Negativity-Constrained Least Squares (fast NNLS) fitting. The paper investigates changes in biochemical components of tissue during stages of elongation, booting, heading, flowering, grain-filling, milk-ripening, dough, and full-ripening...
May 18, 2018: Analytical Chemistry
M Akter, K M Shamim, N F Amin
Neuroanatomy is a vital part of the undergraduate medical (MBBS) Anatomy curriculum of different universities of Bangladesh. The teaching-learning and assessment of Neuroanatomy have gone through significant changes in current times in various parts of the world. Neuroanatomy textbooks are supposed to be useful reflectors of these changes and of the present inclinations. The importance of an understanding approach towards Neuroanatomy is beyond doubt. Consequently, the contemporary Neuroanatomy books are inclined more towards an understanding approach in their presentation...
April 2018: Mymensingh Medical Journal: MMJ
Marion Semmler, Michael Döllinger, Rita R Patel, Anke Ziethe, Anne Schützenberger
OBJECTIVE/HYPOTHESIS: Laser-based three-dimensional (3D) imaging allows realistic visualization and absolute measurement of the vocal folds for comprehensive characterization of the oscillation pattern. STUDY DESIGN: Exploratory study with descriptive data analysis in healthy cohort. METHODS: The custom-developed miniaturized measuring device is an endoscopic camera-laser setup for stereo triangulation and suitable for in vivo application...
March 14, 2018: Laryngoscope
Jessie Y Chen, Mark S Hockenberry, Larry I Lipshultz
INTRODUCTION: Penile deformity is the most obvious manifestation of Peyronie's disease (PD) and key to determining the optimal method of treatment. Other aspects of PD to consider include plaque size, location, and density; amount of calcification; erection quality; disease progression; and penile anatomy. Few standards exist for the objective assessment of these parameters. AIM: To describe current options and new trends in the objective evaluation of PD with a focus on penile curvature and imaging modalities...
February 21, 2018: Sexual Medicine Reviews
Michael L O'Byrne, Andrew C Glatz, Matthew J Gillespie
PURPOSE OF REVIEW: To review current controversies in the transcatheter device closure of ostium secundum atrial septal defects (ASD). RECENT FINDINGS: Transcatheter device closure of ASD (TC-ASD) has well established efficacy and safety. For most individual patients with suitable anatomy, TC-ASD is the preferred method for treating ASD. The availability of large multicenter data sets has made it possible to study practice patterns at a range of hospitals across the United States...
January 2018: Current Opinion in Cardiology
Madeleine J Marsland, Michelle D Lazarus
Social media (SoMe) is increasingly used in higher education (HE) to access knowledge and enable global communication. The SoMe platform Twitter® is particularly beneficial in these contexts because it is readily accessible, easily searchable (via hashtags) and global. Given these advantages, the twitter platform @AskAnatomist was created to foster a global weekly tweet chat, where students and academics can ask and address anatomy-related questions. The aim of this study was to identify themes arising in the early stages of the @AskAnatomy Twitter community to gain insights into current needs/key areas for academic anatomists, students, and other followers...
October 4, 2017: Anatomical Sciences Education
Nirmalya Ghosh, Barbara Holshouser, Udo Oyoyo, Stanley Barnes, Karen Tong, Stephen Ashwal
During human brain development, anatomic regions mature at different rates. Quantitative anatomy-specific analysis of longitudinal diffusion tensor imaging (DTI) and magnetic resonance spectroscopic imaging (MRSI) data may improve our ability to quantify and categorize these maturational changes. Computational tools designed to quickly fuse and analyze imaging information from multiple, technically different datasets would facilitate research on changes during normal brain maturation and for comparison to disease states...
2017: Developmental Neuroscience
Xuming Yang, Mingyuan Qi, Qian Li, Li Chen, Zhongyi Yu, Lin Yang
OBJECTIVE: To study the morphological basis of the role of Siqi (cold as winter, cool as autumn, warm as spring, hot as summer), Wuwei (five flavors: sweet, pungent, salty, sour, and bitter), and Guijing (meridian tropism) through the use of information integration. METHODS: A 14C-2-deoxy-glucose autoradiography method was adopted to determine the overall impact of treatment with 39 herbs on functions of various tissues and organs. Data was measured at 4 hs after a single dose and following the last treatment of repeated doses for a week...
August 2016: Journal of Traditional Chinese Medicine, Chung i Tsa Chih Ying Wen Pan
Guillermo Lorenzo, Michael A Scott, Kevin Tew, Thomas J R Hughes, Yongjie Jessica Zhang, Lei Liu, Guillermo Vilanova, Hector Gomez
Recently, mathematical modeling and simulation of diseases and their treatments have enabled the prediction of clinical outcomes and the design of optimal therapies on a personalized (i.e., patient-specific) basis. This new trend in medical research has been termed "predictive medicine." Prostate cancer (PCa) is a major health problem and an ideal candidate to explore tissue-scale, personalized modeling of cancer growth for two main reasons: First, it is a small organ, and, second, tumor growth can be estimated by measuring serum prostate-specific antigen (PSA, a PCa biomarker in blood), which may enable in vivo validation...
November 29, 2016: Proceedings of the National Academy of Sciences of the United States of America
Jaydeep M Bhatt
Neuromuscular disorders as a group are linked by anatomy with significant differences in pathogenetic mechanisms, clinical expression, and time course of disease. Each neuromuscular disease is relatively uncommon, yet causes a significant burden of disease socioeconomically. Epidemiologic studies in different global regions have demonstrated certain neuromuscular diseases have increased incidence and prevalence rates over time. Understanding differences in global epidemiologic trends will aid clinical research and policies focused on prevention of disease...
November 2016: Neurologic Clinics
John Y K Lee, John T Pierce, Sukhmeet K Sandhu, Dmitriy Petrov, Andrew I Yang
OBJECTIVE Endoscopic surgery has revolutionized surgery of the ventral skull base but has not yet been widely adopted for use in the cerebellopontine angle. Given the relatively normal anatomy of the cerebellopontine angle in patients with trigeminal neuralgia (TN), the authors hypothesized that a fully endoscopic microvascular decompression (E-MVD) might provide pain outcomes equivalent to those of microscopic MVD (M-MVD) but with fewer complications. METHODS The authors conducted a single-institution, single-surgeon retrospective study with patients treated in the period of 2006-2013...
May 2017: Journal of Neurosurgery
İlke Ali Gürses, Osman Coşkun, Başak Gürtekin, Ayşin Kale
AIM: Appreciating the contribution of donor-cadavers to medical education is a well observed practice among anatomists. However, the appreciation of their contribution in research and scientific articles remains dubious. We aimed to evaluate how much data anatomists provide about specimens they have used and how frequently anatomists acknowledge their cadavers in published articles. MATERIALS AND METHODS: We evaluated all articles performed on human cadaveric specimens that were published in Clinical Anatomy and Surgical and Radiologic Anatomy between January 2011 and December 2015...
December 2016: Surgical and Radiologic Anatomy: SRA
Davor Štimac, Sanja Klobučar Majanović, Milan Ličina
Obesity remains a tremendous public health, clinical, and scientific challenge globally. Conventional approaches in the management of obesity offer limited potential for sustained weight loss. Bariatric surgery, although it represents the most effective weight loss treatment, has its own risks and is associated with substantial costs and limited patient applicability. Endoscopic weight loss procedures are considered as the major breakthrough in the management of obesity. Endoluminal interventions performed entirely through the gastrointestinal tract have evolved as a result of an attempt to replicate some of the anatomical features and the physiological effects of the traditional weight loss surgery while being reversible, less invasive, and more cost-effective...
October 2016: Surgical Innovation
S Chebili
The main hypothesis of this paper is the presence of malaise in psychiatry. The malaise has two sides: on one hand, the end of psychiatry hegemony that dominated the theoretical field of psychiatry until the 1990s. The loss of influence of psychoanalysis is due to its inability to be submitted to any kind of assessment. On the other hand, the supremacy of neurosciences. The idea is not to underestimate the importance of neurosciences but rather to affirm that they occupy the whole theoretical field of psychiatry...
April 2016: L'Encéphale
Waqas Shuaib, Juan L Costa
INTRODUCTION: The number of citations an article receives is an important indication of its impact and its contribution to academia. There is a paucity of literature concerning top article citations in diabetes. The main objective of this investigation was to bridge this gap and to provide readers with a practical guide in evaluating diabetes literature. METHODS: Scopus Library was searched to determine the citations of all published diabetes articles. A total of 100 articles were included in our investigation under the subject category 'Diabetes, diabetes mellitus, and diabetics'...
August 2015: Therapeutic Advances in Endocrinology and Metabolism
Masanori Isobe, Jun Miyata, Masaaki Hazama, Hidenao Fukuyama, Toshiya Murai, Hidehiko Takahashi
Visualizing the detailed brain anatomy of individuals with schizophrenia has been made possible by recent advances in magnetic resonance imaging (MRI). Although structural MRI cannot be currently used to diagnose schizophrenia, multimodal MRI can reveal insightful information on key clinical aspects of the pathological physiology of schizophrenia. However, in this regard, the number of multimodal MRI studies is still limited and definitely required. In this review, we discuss how classical and popular theories on the pathological physiology of schizophrenia can be re-examined using neuroimaging studies, and also discuss how multimodal MRI studies may provide additional findings...
January 2016: Neuroscience Research
Awais Mansoor, Ulas Bagci, Brent Foster, Ziyue Xu, Georgios Z Papadakis, Les R Folio, Jayaram K Udupa, Daniel J Mollura
The computer-based process of identifying the boundaries of lung from surrounding thoracic tissue on computed tomographic (CT) images, which is called segmentation, is a vital first step in radiologic pulmonary image analysis. Many algorithms and software platforms provide image segmentation routines for quantification of lung abnormalities; however, nearly all of the current image segmentation approaches apply well only if the lungs exhibit minimal or no pathologic conditions. When moderate to high amounts of disease or abnormalities with a challenging shape or appearance exist in the lungs, computer-aided detection systems may be highly likely to fail to depict those abnormal regions because of inaccurate segmentation methods...
July 2015: Radiographics: a Review Publication of the Radiological Society of North America, Inc
M Shang, M Sands, W Bolch
PURPOSE: Large animal models, most popularly beagles, have been crucial surrogates to humans in determining radiation safety levels of radiopharmaceuticals. This study aims to develop a detailed beagle phantom to accurately approximate organ absorbed doses for therapy nuclear medicine preclinical studies. METHODS: A 3D NURBS model was created subordinate to a whole body CT of an adult beagle. Bones were harvested and CT imaged to offer macroscopic skeletal detail...
June 2015: Medical Physics
Faizal Rayan, Shashi Kumar Nanjayan, Conal Quah, Darryl Ramoutar, Sujith Konan, Fares S Haddad
Anterior cruciate ligament (ACL) rupture is one of the commonest knee sport injuries. The annual incidence of the ACL injury is between 100000-200000 in the United States. Worldwide around 400000 ACL reconstructions are performed in a year. The goal of ACL reconstruction is to restore the normal knee anatomy and kinesiology. The tibial and femoral tunnel placements are of primordial importance in achieving this outcome. Other factors that influence successful reconstruction are types of grafts, surgical techniques and rehabilitation programmes...
March 18, 2015: World Journal of Orthopedics
Tara M Mastracci, Matthew J Eagleton, Yuki Kuramochi, Shona Bathurst, Katherine Wolski
OBJECTIVE: The practice of using fenestrated endografts to treat juxtarenal and group IV thoracoabdominal aortic aneurysms (TAAAs) has become more accepted, but long-term outcomes are still unknown. We report long-term survival, complications, and branch-related outcomes from a single-center experience. METHODS: The study included consecutive patients enrolled prospectively into a physician-sponsored investigational device exemption classified as undergoing group IV TAAA or juxtarenal aneurysm repair by the treating surgeon using fenestrated endografts...
February 2015: Journal of Vascular Surgery
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