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https://www.readbyqxmd.com/read/28339750/downstream-overdrive-pacing-and-intracardiac-concealed-fusion-to-guide-rapid-identification-of-atrial-tachycardia-after-atrial-fibrillation-ablation
#1
Chirag R Barbhaiya, Samuel H Baldinger, Saurabh Kumar, Jason S Chinitz, Alan D Enriquez, Roy John, William G Stevenson, Gregory F Michaud
Aims: Atrial tachycardia (AT) related to atrial fibrillation (AF) ablation frequently poses a diagnostic challenge. Downstream overdrive pacing (DOP) can be used to rapidly detect reentry and assess proximity of a pacing site to an AT circuit or focus. We hypothesized that systematic DOP using multielectrode catheters would facilitate AT mapping. Methods and results: DOP identified constant fusion when the post-pacing interval (PPI)-tachycardia cycle length (TCL) <40 ms and stimulus to adjacent upstream atrial electrogram interval >75% of TCL...
February 17, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28339197/correction-to-opportunistic-sampling-of-roadkill-as-an-entry-point-to-accessing-natural-products-assembled-by-bacteria-associated-with-non-anthropoidal-mammalian-microbiomes
#2
Jeremy L Motley, Blake W Stamps, Carter A Mitchell, Alec T Thompson, Jayson Cross, Jianlan You, Douglas R Powell, Bradley S Stevenson, Robert H Cichewicz
No abstract text is available yet for this article.
March 24, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28334232/walking-responses-of-tribolium-castaneum-coleoptera-tenebrionidae-to-its-aggregation-pheromone-and-odors-of-wheat-infestations
#3
B J Stevenson, L Cai, C Faucher, M Michie, A Berna, Y Ren, A Anderson, S Chyb, W Xu
The red flour beetle, Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae), is a worldwide pest of stored grains. Using "Y"-tube olfactometry we studied the response of T. castaneum to odors from simulated wheat infestations containing conspecifics, and infestations containing the lesser grain borer, Rhyzopertha dominica (F.) (Coleoptera: Bostrichidae), and the granary weevil Sitophilus granarius (L.) (Coleoptera: Curculionidae). Tribolium castaneum larvae were significantly attracted to odors from all three test species...
March 3, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28331428/observation-of-formula-see-text-and-formula-see-text-decays
#4
R Aaij, B Adeva, M Adinolfi, Z Ajaltouni, S Akar, J Albrecht, F Alessio, M Alexander, S Ali, G Alkhazov, P Alvarez Cartelle, A A Alves, S Amato, S Amerio, Y Amhis, L An, L Anderlini, G Andreassi, M Andreotti, J E Andrews, R B Appleby, F Archilli, P d'Argent, J Arnau Romeu, A Artamonov, M Artuso, E Aslanides, G Auriemma, M Baalouch, I Babuschkin, S Bachmann, J J Back, A Badalov, C Baesso, S Baker, W Baldini, R J Barlow, C Barschel, S Barsuk, W Barter, M Baszczyk, V Batozskaya, B Batsukh, V Battista, A Bay, L Beaucourt, J Beddow, F Bedeschi, I Bediaga, L J Bel, V Bellee, N Belloli, K Belous, I Belyaev, E Ben-Haim, G Bencivenni, S Benson, J Benton, A Berezhnoy, R Bernet, A Bertolin, C Betancourt, F Betti, M-O Bettler, M van Beuzekom, Ia Bezshyiko, S Bifani, P Billoir, T Bird, A Birnkraut, A Bitadze, A Bizzeti, T Blake, F Blanc, J Blouw, S Blusk, V Bocci, T Boettcher, A Bondar, N Bondar, W Bonivento, I Bordyuzhin, A Borgheresi, S Borghi, M Borisyak, M Borsato, F Bossu, M Boubdir, T J V Bowcock, E Bowen, C Bozzi, S Braun, M Britsch, T Britton, J Brodzicka, E Buchanan, C Burr, A Bursche, J Buytaert, S Cadeddu, R Calabrese, M Calvi, M Calvo Gomez, A Camboni, P Campana, D H Campora Perez, L Capriotti, A Carbone, G Carboni, R Cardinale, A Cardini, P Carniti, L Carson, K Carvalho Akiba, G Casse, L Cassina, L Castillo Garcia, M Cattaneo, Ch Cauet, G Cavallero, R Cenci, M Charles, Ph Charpentier, G Chatzikonstantinidis, M Chefdeville, S Chen, S-F Cheung, V Chobanova, M Chrzaszcz, X Cid Vidal, G Ciezarek, P E L Clarke, M Clemencic, H V Cliff, J Closier, V Coco, J Cogan, E Cogneras, V Cogoni, L Cojocariu, G Collazuol, P Collins, A Comerma-Montells, A Contu, A Cook, G Coombs, S Coquereau, G Corti, M Corvo, C M Costa Sobral, B Couturier, G A Cowan, D C Craik, A Crocombe, M Cruz Torres, S Cunliffe, R Currie, C D'Ambrosio, F Da Cunha Marinho, E Dall'Occo, J Dalseno, P N Y David, A Davis, O De Aguiar Francisco, K De Bruyn, S De Capua, M De Cian, J M De Miranda, L De Paula, M De Serio, P De Simone, C-T Dean, D Decamp, M Deckenhoff, L Del Buono, M Demmer, A Dendek, D Derkach, O Deschamps, F Dettori, B Dey, A Di Canto, H Dijkstra, F Dordei, M Dorigo, A Dosil Suárez, A Dovbnya, K Dreimanis, L Dufour, G Dujany, K Dungs, P Durante, R Dzhelyadin, A Dziurda, A Dzyuba, N Déléage, S Easo, M Ebert, U Egede, V Egorychev, S Eidelman, S Eisenhardt, U Eitschberger, R Ekelhof, L Eklund, S Ely, S Esen, H M Evans, T Evans, A Falabella, N Farley, S Farry, R Fay, D Fazzini, D Ferguson, A Fernandez Prieto, F Ferrari, F Ferreira Rodrigues, M Ferro-Luzzi, S Filippov, R A Fini, M Fiore, M Fiorini, M Firlej, C Fitzpatrick, T Fiutowski, F Fleuret, K Fohl, M Fontana, F Fontanelli, D C Forshaw, R Forty, V Franco Lima, M Frank, C Frei, J Fu, E Furfaro, C Färber, A Gallas Torreira, D Galli, S Gallorini, S Gambetta, M Gandelman, P Gandini, Y Gao, L M Garcia Martin, J García Pardiñas, J Garra Tico, L Garrido, P J Garsed, D Gascon, C Gaspar, L Gavardi, G Gazzoni, D Gerick, E Gersabeck, M Gersabeck, T Gershon, Ph Ghez, S Gianì, V Gibson, O G Girard, L Giubega, K Gizdov, V V Gligorov, D Golubkov, A Golutvin, A Gomes, I V Gorelov, C Gotti, E Govorkova, M Grabalosa Gándara, R Graciani Diaz, L A Granado Cardoso, E Graugés, E Graverini, G Graziani, A Grecu, P Griffith, L Grillo, B R Gruberg Cazon, O Grünberg, E Gushchin, Yu Guz, T Gys, C Göbel, T Hadavizadeh, C Hadjivasiliou, G Haefeli, C Haen, S C Haines, S Hall, B Hamilton, X Han, S Hansmann-Menzemer, N Harnew, S T Harnew, J Harrison, M Hatch, J He, T Head, A Heister, K Hennessy, P Henrard, L Henry, J A Hernando Morata, E van Herwijnen, M Heß, A Hicheur, D Hill, C Hombach, H Hopchev, W Hulsbergen, T Humair, M Hushchyn, N Hussain, D Hutchcroft, M Idzik, P Ilten, R Jacobsson, A Jaeger, J Jalocha, E Jans, A Jawahery, F Jiang, M John, D Johnson, C R Jones, C Joram, B Jost, N Jurik, S Kandybei, W Kanso, M Karacson, J M Kariuki, S Karodia, M Kecke, M Kelsey, I R Kenyon, M Kenzie, T Ketel, E Khairullin, B Khanji, C Khurewathanakul, T Kirn, S Klaver, K Klimaszewski, S Koliiev, M Kolpin, I Komarov, R F Koopman, P Koppenburg, A Kosmyntseva, A Kozachuk, M Kozeiha, L Kravchuk, K Kreplin, M Kreps, P Krokovny, F Kruse, W Krzemien, W Kucewicz, M Kucharczyk, V Kudryavtsev, A K Kuonen, K Kurek, T Kvaratskheliya, D Lacarrere, G Lafferty, A Lai, G Lanfranchi, C Langenbruch, T Latham, C Lazzeroni, R Le Gac, J van Leerdam, J-P Lees, A Leflat, J Lefrançois, R Lefèvre, F Lemaitre, E Lemos Cid, O Leroy, T Lesiak, B Leverington, Y Li, T Likhomanenko, R Lindner, C Linn, F Lionetto, B Liu, X Liu, D Loh, I Longstaff, J H Lopes, D Lucchesi, M Lucio Martinez, H Luo, A Lupato, E Luppi, O Lupton, A Lusiani, X Lyu, F Machefert, F Maciuc, O Maev, K Maguire, S Malde, A Malinin, T Maltsev, G Manca, G Mancinelli, P Manning, J Maratas, J F Marchand, U Marconi, C Marin Benito, P Marino, J Marks, G Martellotti, M Martin, M Martinelli, D Martinez Santos, F Martinez Vidal, D Martins Tostes, L M Massacrier, A Massafferri, R Matev, A Mathad, Z Mathe, C Matteuzzi, A Mauri, B Maurin, A Mazurov, M McCann, J McCarthy, A McNab, R McNulty, B Meadows, F Meier, M Meissner, D Melnychuk, M Merk, A Merli, E Michielin, D A Milanes, M-N Minard, D S Mitzel, A Mogini, J Molina Rodriguez, I A Monroy, S Monteil, M Morandin, P Morawski, A Mordà, M J Morello, J Moron, A B Morris, R Mountain, F Muheim, M Mulder, M Mussini, D Müller, J Müller, K Müller, V Müller, P Naik, T Nakada, R Nandakumar, A Nandi, I Nasteva, M Needham, N Neri, S Neubert, N Neufeld, M Neuner, A D Nguyen, T D Nguyen, C Nguyen-Mau, S Nieswand, R Niet, N Nikitin, T Nikodem, A Novoselov, D P O'Hanlon, A Oblakowska-Mucha, V Obraztsov, S Ogilvy, R Oldeman, C J G Onderwater, J M Otalora Goicochea, A Otto, P Owen, A Oyanguren, P R Pais, A Palano, F Palombo, M Palutan, J Panman, A Papanestis, M Pappagallo, L L Pappalardo, W Parker, C Parkes, G Passaleva, A Pastore, G D Patel, M Patel, C Patrignani, A Pearce, A Pellegrino, G Penso, M Pepe Altarelli, S Perazzini, P Perret, L Pescatore, K Petridis, A Petrolini, A Petrov, M Petruzzo, E Picatoste Olloqui, B Pietrzyk, M Pikies, D Pinci, A Pistone, A Piucci, S Playfer, M Plo Casasus, T Poikela, F Polci, A Poluektov, I Polyakov, E Polycarpo, G J Pomery, A Popov, D Popov, B Popovici, S Poslavskii, C Potterat, E Price, J D Price, J Prisciandaro, A Pritchard, C Prouve, V Pugatch, A Puig Navarro, G Punzi, W Qian, R Quagliani, B Rachwal, J H Rademacker, M Rama, M Ramos Pernas, M S Rangel, I Raniuk, F Ratnikov, G Raven, F Redi, S Reichert, A C Dos Reis, C Remon Alepuz, V Renaudin, S Ricciardi, S Richards, M Rihl, K Rinnert, V Rives Molina, P Robbe, A B Rodrigues, E Rodrigues, J A Rodriguez Lopez, P Rodriguez Perez, A Rogozhnikov, S Roiser, A Rollings, V Romanovskiy, A Romero Vidal, J W Ronayne, M Rotondo, M S Rudolph, T Ruf, P Ruiz Valls, J J Saborido Silva, E Sadykhov, N Sagidova, B Saitta, V Salustino Guimaraes, C Sanchez Mayordomo, B Sanmartin Sedes, R Santacesaria, C Santamarina Rios, M Santimaria, E Santovetti, A Sarti, C Satriano, A Satta, D M Saunders, D Savrina, S Schael, M Schellenberg, M Schiller, H Schindler, M Schlupp, M Schmelling, T Schmelzer, B Schmidt, O Schneider, A Schopper, K Schubert, M Schubiger, M-H Schune, R Schwemmer, B Sciascia, A Sciubba, A Semennikov, A Sergi, N Serra, J Serrano, L Sestini, P Seyfert, M Shapkin, I Shapoval, Y Shcheglov, T Shears, L Shekhtman, V Shevchenko, B G Siddi, R Silva Coutinho, L Silva de Oliveira, G Simi, S Simone, M Sirendi, N Skidmore, T Skwarnicki, E Smith, I T Smith, J Smith, M Smith, H Snoek, M D Sokoloff, F J P Soler, B Souza De Paula, B Spaan, P Spradlin, S Sridharan, F Stagni, M Stahl, S Stahl, P Stefko, S Stefkova, O Steinkamp, S Stemmle, O Stenyakin, S Stevenson, S Stoica, S Stone, B Storaci, S Stracka, M Straticiuc, U Straumann, L Sun, W Sutcliffe, K Swientek, V Syropoulos, M Szczekowski, T Szumlak, S T'Jampens, A Tayduganov, T Tekampe, G Tellarini, F Teubert, E Thomas, J van Tilburg, M J Tilley, V Tisserand, M Tobin, S Tolk, L Tomassetti, D Tonelli, S Topp-Joergensen, F Toriello, E Tournefier, S Tourneur, K Trabelsi, M Traill, M T Tran, M Tresch, A Trisovic, A Tsaregorodtsev, P Tsopelas, A Tully, N Tuning, A Ukleja, A Ustyuzhanin, U Uwer, C Vacca, V Vagnoni, A Valassi, S Valat, G Valenti, A Vallier, R Vazquez Gomez, P Vazquez Regueiro, S Vecchi, M van Veghel, J J Velthuis, M Veltri, G Veneziano, A Venkateswaran, M Vernet, M Vesterinen, B Viaud, D Vieira, M Vieites Diaz, H Viemann, X Vilasis-Cardona, M Vitti, V Volkov, A Vollhardt, B Voneki, A Vorobyev, V Vorobyev, C Voß, J A de Vries, C Vázquez Sierra, R Waldi, C Wallace, R Wallace, J Walsh, J Wang, D R Ward, H M Wark, N K Watson, D Websdale, A Weiden, M Whitehead, J Wicht, G Wilkinson, M Wilkinson, M Williams, M P Williams, M Williams, T Williams, F F Wilson, J Wimberley, J Wishahi, W Wislicki, M Witek, G Wormser, S A Wotton, K Wraight, K Wyllie, Y Xie, Z Xing, Z Xu, Z Yang, H Yin, J Yu, X Yuan, O Yushchenko, K A Zarebski, M Zavertyaev, L Zhang, Y Zhang, Y Zhang, A Zhelezov, Y Zheng, A Zhokhov, X Zhu, V Zhukov, S Zucchelli
The decays [Formula: see text] and [Formula: see text] are observed for the first time using a data sample corresponding to an integrated luminosity of 3.0 fb[Formula: see text], collected by the LHCb experiment in proton-proton collisions at the centre-of-mass energies of 7 and 8[Formula: see text]. The branching fractions relative to that of [Formula: see text] are measured to be [Formula: see text]where the first uncertainties are statistical and the second are systematic.
2017: European Physical Journal. C, Particles and Fields
https://www.readbyqxmd.com/read/28330414/male-subfertility-as-a-chronic-illness-the-role-of-adaptive-challenges
#5
Eleanor L Stevenson, Kevin R McEleny
Male factor infertility (MFI) is extremely common, often with several associated chronic health conditions. Because a man's fertility assessment may be their first contact with health services, the health care team has a responsibility to act as male health advocates to ensure comprehensive care. The diagnosis of subfertility allows a broader view of these men as patients with a chronic illness who have complex health needs. Because of the associated complexity of care following evaluation, there needs to be new approach in how men affected by MFI should be managed long term...
March 22, 2017: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/28329442/poly-ether-ester-ionomers-as-water-soluble-polymers-for-material-extrusion-additive-manufacturing-processes
#6
Allison M Pekkanen, Callie Zawaski, Andre Stevenson, Ross Dickerman, Abby Whittington, Christopher Bryant Williams, Timothy E Long
Water-soluble polymers as sacrificial supports for additive manufacturing (AM) facilitate complex features in printed objects. Few water-soluble polymers beyond poly(vinyl alcohol) enable material extrusion AM. In this work, charged poly(ether ester)s with tailored rheological and mechanical properties serve as novel materials for extrusion-based AM at low temperatures. Melt transesterification of poly(ethylene glycol) (PEG, 8k) and dimethyl 5-sulfoisophthalate afforded poly(ether ester)s of sufficient molecular weight to impart mechanical integrity...
March 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28329160/maternal-microchimerism-predicts-increased-infection-but-decreased-disease-due-to-p-falciparum-during-early-childhood
#7
Whitney E Harrington, Sami B Kanaan, Atis Muehlenbachs, Robert Morrison, Philip Stevenson, Michal Fried, Patrick E Duffy, J Lee Nelson
BACKGROUND: A mother's infection with placental malaria (PM) can affect her child's susceptibility to malaria, although the mechanism remains unclear. The fetus acquires a small amount of maternal cells and DNA known as maternal microchimerism (MMc), and we hypothesized that PM increases MMc and that MMc alters risk of P. falciparum malaria during infancy. METHODS: In a nested cohort from Muheza, Tanzania, we evaluated the presence and level of cord blood MMc in offspring of women with and without PM...
March 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28328927/effect-of-phosphorus-stress-on-microcystis-aeruginosa-growth-and-phosphorus-uptake
#8
Sajeela Ghaffar, R Jan Stevenson, Zahiruddin Khan
This study was designed to advance understanding of phosphorus regulation of Microcystis aeruginosa growth, phosphorus uptake and storage in changing phosphorus (P) conditions as would occur in lakes. We hypothesized that Microcystis growth and nutrient uptake would fit classic models by Monod, Droop, and Michaelis-Menten in these changing conditions. Microcystis grown in luxury nutrient concentrations was transferred to treatments with phosphorus concentrations ranging from 0-256 μg P∙L-1 and luxury nitrogen...
2017: PloS One
https://www.readbyqxmd.com/read/28324261/prophylactic-anticonvulsants-in-intracerebral-hemorrhage
#9
Jason Mackey, Ashley D Blatsioris, Elizabeth A S Moser, Ravan J L Carter, Chandan Saha, Alec Stevenson, Abigail L Hulin, Darren P O'Neill, Aaron A Cohen-Gadol, Thomas J Leipzig, Linda S Williams
BACKGROUND AND PURPOSE: Prophylactic anticonvulsants are routinely prescribed in the acute setting for intracerebral hemorrhage (ICH) patients, but some studies have reported an association with worse outcomes. We sought to characterize the prevalence and predictors of prophylactic anticonvulsant administration after ICH as well as guideline adherence. We also sought to determine whether prophylactic anticonvulsants were independently associated with poor outcome. METHODS: We performed a retrospective study of primary ICH in our two academic centers...
March 21, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28323934/menopausal-hormone-therapy-and-type-2-diabetes-prevention-evidence-mechanisms-and-clinical-implications
#10
Franck Mauvais-Jarvis, JoAnn E Manson, John C Stevenson, Vivian A Fonseca
Type 2 diabetes has reached epidemic proportions in the US. Large randomized controlled trials suggest that menopausal hormone therapy (MHT) delays the onset of type 2 diabetes in women. Still, the mechanisms and clinical implications of these associations are a matter of controversy. This review provides an up-to-date analysis and integration of epidemiological, clinical and basic studies, and proposes a mechanistic explanation for the effect of menopause and MHT on type 2 diabetes development and prevention...
March 8, 2017: Endocrine Reviews
https://www.readbyqxmd.com/read/28323574/the-effects-of-an-increased-calorie-breakfast-consumed-prior-to-simulated-match-play-in-academy-soccer-players
#11
Marc A Briggs, Liam D Harper, Ged McNamee, Emma Cockburn, Penny L S Rumbold, Emma J Stevenson, Mark Russell
Dietary analysis of Academy soccer players highlights that total energy and carbohydrate intakes are less than optimal, especially, on match-days. As UK Academy matches predominantly kick-off at ∼11:00 h, breakfast is likely the last pre-exercise meal and thus may provide an intervention opportunity on match-day. Accordingly, the physiological and performance effects of an increased calorie breakfast consumed ∼135-min before soccer-specific exercise was investigated. English Premier League Academy soccer players (n = 7) repeated a 90-min soccer match simulation on two occasions after consumption of habitual (Bhab; ∼1100 kJ) or increased (Binc; ∼2100 kJ) energy breakfasts standardised for macronutrient contributions (∼60% carbohydrates, ∼15% proteins and ∼25% fats)...
March 21, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28320532/atypical-histiocytosis-in-red-squirrels-sciurus-vulgaris
#12
S H Smith, K Stevenson, J Del-Pozo, S Moss, A Meredith
Four red squirrels (Sciurus vulgaris) were subjected to necropsy examination over a 3-year period as part of a broader surveillance study. The squirrels presented with cutaneous, subcutaneous and/or internal swellings and nodules that consisted microscopically of sheets of atypical round cells and multinucleated giant cells. There was moderate anisokaryosis with rare mitoses. Nuclei ranged from oval to indented or C-shaped and some were bizarre, twisted or multilobulated. Many giant cells also had a bizarre morphology, with anisokaryosis within individual cells...
March 17, 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28320455/a-systematic-review-of-taeniasis-cysticercosis-and-trichinellosis-in-vietnam
#13
REVIEW
Dinh Ng-Nguyen, Mark A Stevenson, Rebecca J Traub
Taeniasis, cysticercosis and trichinellosis have been ranked as the most important food-borne parasites of humans in terms of public health, socioeconomic and trade impact. Despite this, information on these food-borne zoonoses in Vietnam is scarce and fragmented, and many local reports remain inaccessible to the international research community. This study aims to conduct comprehensive literature searches to report on the incidence and estimate the true prevalence of taeniasis in humans and T. solium cysticercosis in humans and pigs in Vietnam utilizing Bayesian models; in addition, to report the incidence and the distribution of trichinellosis...
March 21, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28320059/effects-of-treadmill-exercise-on-advanced-osteoarthritis-pain-in-rats
#14
Joshua Allen, Ian Imbert, Joshua Havelin, Terry Henderson, Glenn Stevenson, Lucy Liaw, Tamara King
OBJECTIVE: Exercise is commonly recommended for patients with osteoarthritis (OA) pain. However, whether exercise is beneficial in ameliorating persistent NSAID-resistant ongoing pain associated with advanced OA is unknown. METHODS: Rats treated with intra-articular monosodium iodoacetate (MIA) or saline underwent treadmill exercise or remained sedentary starting 10 days post-injection. Tactile sensory thresholds and weight bearing were assessed followed by radiographs at weekly intervals...
March 20, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28318647/prospective-evaluation-of-peripherally-inserted-central-catheter-complications-in-both-inpatient-and-outpatient-settings
#15
Christina Liscynesky, Jessica Johnston, Kelci E Haydocy, Kurt B Stevenson
We describe a prospective observational cohort (N = 187) to evaluate peripherally inserted central catheter line complications concurrently from the time of placement until removal. A significantly higher percentage of patients who experienced intraluminal thrombosis were receiving total parenteral nutrition (P ≤ .001) and had a dual lumen catheter (P = .01). Among patients with a confirmed or suspected infection, a significantly higher proportion received total parenteral nutrition (P = .01), had dual-lumen catheters (P = ...
March 16, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28317311/novel-pathogenic-variants-in-foxp3-in-fetuses-with-echogenic-bowel-and-skin-desquamation-identified-by-ultrasound
#16
Raymond J Louie, Queenie K-G Tan, Jennifer B Gilner, R Curtis Rogers, Noelle Younge, Stephanie B Wechsler, Marie T McDonald, Barbara Gordon, Christopher A Saski, Julie R Jones, Shelley J Chapman, Roger E Stevenson, John W Sleasman, Michael J Friez
Immunodysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) syndrome is a rare, X-linked recessive disease that affects regulatory T cells (Tregs) resulting in diarrhea, enteropathy, eczema, and insulin-dependent diabetes mellitus. IPEX syndrome is caused by pathogenic alterations in FOXP3 located at Xp11.23. FOXP3 encodes a transcription factor that interacts with several partners, including NFAT and NF-κB, and is necessary for the proper cellular differentiation of Tregs. Although variable, the vast majority of IPEX syndrome patients have onset of disease during infancy with severe enteropathy...
March 20, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28317249/getting-back-to-the-dissecting-room-an-evaluation-of-an-innovative-course-in-musculoskeletal-anatomy-for-uk-based-rheumatology-training
#17
Tim Blake, Debbi Marais, Andrew B Hassell, Kay Stevenson, Zoe Paskins
BACKGROUND: The rheumatologist relies heavily on clinical skills to diagnose diverse conditions, something that is correlated with one's knowledge of clinical anatomy. More recently, rheumatology has offered further career flexibility with opportunities to develop skills such as joint injection and musculoskeletal (MSK) ultrasound, both of which require a sound understanding of anatomy. Currently, there are no formal strategies to support competency-based anatomy learning in rheumatology in the UK...
March 20, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/28303193/biodiversity-in-agricultural-landscapes-the-effect-of-apple-cultivar-on-epiphyte-diversity
#18
C Robin Stevenson, Chantel Davies, Jennifer K Rowntree
In natural systems, extended phenotypes of trees can be important in determining the species composition and diversity of associated communities. Orchards are productive systems where trees dominate, and can be highly biodiverse, but few studies have considered the importance of tree genetic background in promoting associated biodiversity. We tested the effect of apple cultivar (plant genetic background) on the diversity and composition of the associated epiphytic bryophyte community across a total of seven cultivars in five productive East Anglian orchards where each orchard contained two cultivars...
February 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28301482/forest-biomass-density-across-large-climate-gradients-in-northern-south-america-is-related-to-water-availability-but-not-with-temperature
#19
Esteban Álvarez-Dávila, Luis Cayuela, Sebastián González-Caro, Ana M Aldana, Pablo R Stevenson, Oliver Phillips, Álvaro Cogollo, Maria C Peñuela, Patricio von Hildebrand, Eliana Jiménez, Omar Melo, Ana Catalina Londoño-Vega, Irina Mendoza, Oswaldo Velásquez, Fernando Fernández, Marcela Serna, Cesar Velázquez-Rua, Doris Benítez, José M Rey-Benayas
Understanding and predicting the likely response of ecosystems to climate change are crucial challenges for ecology and for conservation biology. Nowhere is this challenge greater than in the tropics as these forests store more than half the total atmospheric carbon stock in their biomass. Biomass is determined by the balance between biomass inputs (i.e., growth) and outputs (mortality). We can expect therefore that conditions that favor high growth rates, such as abundant water supply, warmth, and nutrient-rich soils will tend to correlate with high biomass stocks...
2017: PloS One
https://www.readbyqxmd.com/read/28301363/the-plastic-surgeon-as-employee-a-pilot-survey-of-the-california-society-of-plastic-surgeons
#20
Nirav Bipin Patel, Demetrius M Coombs, Mena Arsalai, Chin-Shang Li, Yu Liu, Thomas R Stevenson, Lee L Q Pu
INTRODUCTION: Plastic surgeons endure years of training yet remain poorly equipped to negotiate first employment contracts. Our aims were to evaluate typical plastic surgeon employment contracts and assess contract comprehensiveness. We sought elements that should be included to better preserve varied interests. METHODS: A brief, anonymous, e-mailed survey was sent to California Society of Plastic Surgeons members and responses collected over 2 months. We collected information such as years in practice, geographic area, types of practices and number of surgeons within them, and legal standing of partnerships...
March 16, 2017: Annals of Plastic Surgery
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