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https://www.readbyqxmd.com/read/28817725/development-of-a-psychological-intervention-for-fatigue-after-stroke
#1
Simiao Wu, Trudie Chalder, Kirstin E Anderson, David Gillespie, Malcolm R Macleod, Gillian E Mead
BACKGROUND AND AIM: Post-stroke fatigue (PSF) is common and distressing, but there is insufficient evidence to recommend any effective treatment for it. Psychological interventions are effective in treating fatigue in other conditions. This paper describes the development and evaluation of the feasibility of a psychological intervention for PSF. METHODS: Based on psychological correlates of PSF and evidence-based psychological interventions for fatigue in other medical conditions, we developed a manualised psychological intervention for PSF, with input from stroke clinicians, psychological therapists, and stroke survivors...
2017: PloS One
https://www.readbyqxmd.com/read/28812635/divergent-plant-soil-feedbacks-could-alter-future-elevation-ranges-and-ecosystem-dynamics
#2
Michael E Van Nuland, Joseph K Bailey, Jennifer A Schweitzer
Plant-soil feedbacks (PSF) are important interactions that may influence range dynamics in a changing world. What remains largely unknown is the generality of plant-soil biotic interactions across populations and the potential role of specific soil biota, both of which are key for understanding how PSF might change future communities and ecosystems. We combined landscape-level field observations and experimental soil treatments to test whether a dominant tree alters soil environments to impact its own performance and range shifts towards higher elevations...
April 28, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28810637/binding-of-line-1-rna-to-psf-transcriptionally-promotes-gage6-and-regulates-cell-proliferation-and-tumor-formation-in-vitro
#3
Jiao Lv, Ziyi Zhao
Hepatocellular carcinoma (HCC) has one of the highest mortality rates among numerous types of cancer. It has been demonstrated that in hepatitis B (HBV)-associated HCC, the expression of chimeric fusion transcript HBx-long interspersed nuclear element-1 (LINE-1) initiated by HBV integration is correlated with hepatocarcinogenesis and poor patient survival rates. Furthermore, increased rates of LINE-1 hypomethylation have been detected in HCC tissues compared with adjacent tissues. This suggests that individual LINE-1 RNA (L1 RNA) serves an important role in the processes of hepatocarcinogenesis...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28808586/quality-of-vision-after-deep-anterior-lamellar-keratoplasty-fluid-dissection-compared-to-penetrating-keratoplasty-for-the-treatment-of-keratoconus
#4
Islam Mahmoud Hamdi, Momen Mahmoud Hamdi
PURPOSE: To compare the visual quality of patients with keratoconus who underwent penetrating keratoplasty (PKP) or deep anterior lamellar keratoplasty (DALK) with fluid dissection. DESIGN: Cross-sectional, observational study. METHODS: Twelve eyes that underwent PKP (PKP group) were compared to 24 eyes that underwent DALK (DALK group) after complete removal of sutures and stability of refraction. Visual, refractive, corneal topographic, corneal aberrometry, and ocular aberrometry parameters were compared for both groups...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28805367/tailoring-membrane-surface-properties-and-ultrafiltration-performances-via-self-assembly-of-polyethylene-glycol-block-polysulfone-block-polyethylene-glycol-block-copolymer-upon-thermal-and-solvent-annealing
#5
Ning Wang, Tao Wang, Yunxia Hu
Recently, ultrafiltration (UF) membranes faced great challenges including the fine control of the membrane surfaces for high filtration performances and antifouling properties in treating complex solution systems. Here, a particular type of amphiphilic block copolymers polyethylene glycol-block-polysulfone-block-polyethylene glycol (PEG-b-PSf-b-PEG) was synthesized through one-pot step-growth polymerization with mPEG as two ends to achieve the mobility of hydrophilic polymer chains. Without any other polymers or additives involved, the PEG-b-PSf-b-PEG triblock copolymer UF membrane was fabricated through the non-solvent induced phase separation (NIPS) method...
August 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28802172/interaction-of-phenazinium-based-photosensitizers-with-the-n-and-b-isoforms-of-human-serum-albumin-effect-of-methyl-substitution
#6
Swagata Sen, Riya Sett, Bijan K Paul, Nikhil Guchhait
The present work is focused on exploring the interaction of two phenazinium-based biological photosensitizers, phenosafranin (PSF) and safranin-O (SO), with human serum albumin (HSA), with particular emphasis on the physiologically significant NB conformational transition of the protein on the dye:HSA interaction. In addition, the presence of methyl substitution on the planar phenazinium ring in SO paves way for looking into the effect of simple chemical manipulation (that is, methyl substitution on the dye nucleus) on the dye:protein interaction behavior as a function of various (pH-induced) isoforms of HSA...
August 3, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28777462/generation-of-realistic-virtual-nodules-based-on-three-dimensional-spatial-resolution-in-lung-computed-tomography-a-pilot-phantom-study
#7
Akihiro Narita, Masaki Ohkubo, Kohei Murao, Toru Matsumoto, Shinichi Wada
PURPOSE: The aim of this feasibility study using phantoms was to propose a novel method for obtaining computer-generated realistic virtual nodules in lung computed tomography (CT). METHODS: In the proposed methodology, pulmonary nodule images obtained with a CT scanner are deconvolved with the point spread function (PSF) in the scan plane and slice sensitivity profile (SSP) measured for the scanner; the resultant images are referred to as nodule-like object functions...
August 4, 2017: Medical Physics
https://www.readbyqxmd.com/read/28764891/2-methoxyethylacrylate-modified-polysulfone-membrane-and-its-blood-compatibility
#8
Xin Tian, Yun-Ren Qiu
Hydrophilic material of 2-methoxyethylacrylate (MEA) was grafted from polysulfone (PSF) membrane via Michael addition reaction. The (1)H-nuclear magnetic resonance ((1)H NMR) and X-ray photoelectron spectroscopy (XPS) characterizations of the modified membrane showed that MEA had been successfully grafted onto PSF membrane surface. The water contact angle of the membrane surface was tested. The results showed that the water contact angle changed from 76° to 59.5°, it means that the hydrophilicity of the modified membrane was improved...
July 29, 2017: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/28738760/substitution-urethroplasty-for-anterior-urethral-stricture-repair-comparison-between-lingual-mucosa-graft-and-pedicled-skin-flap
#9
Qiang Fu, Yumeng Zhang, Jiong Zhang, Hong Xie, Ying-Long Sa, Sanbao Jin
OBJECTIVES: The aim of this study was to compare the effectiveness and outcomes of lingual mucosa graft (LMG) urethroplasty versus pedicled skin flap (PSF) urethroplasty in the repair of anterior urethral strictures. MATERIALS AND METHODS: A retrospective study in one urological center examined 293 male patients with anterior urethral strictures who received substitution urethroplasty from 2006 to 2015. Of these, 199 patients received PSF urethroplasty and 94 received LMG urethroplasty...
July 25, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28732606/visual-performance-after-bilateral-implantation-of-2-new-presbyopia-correcting-intraocular-lenses-trifocal-versus-extended-range-of-vision
#10
Gaspare Monaco, Mariangela Gari, Fabio Di Censo, Andrea Poscia, Giada Ruggi, Antonio Scialdone
PURPOSE: To compare the visual outcomes and quality of vision of 2 new diffractive multifocal intraocular lenses (IOLs) with those of a monofocal IOL. SETTING: Fatebenefratelli e Oftalmico Hospital, Milan, Italy. DESIGN: Prospective case series. METHODS: Patients had bilateral cataract surgery with implantation of a trifocal IOL (Panoptix), an extended-range-of-vision IOL (Symfony), or a monofocal IOL (SN60WF). Postoperative examinations included assessing distance, intermediate, and near visual acuity; binocular defocus; intraocular and total aberrations; point-spread function (PSF); modulation transfer function (MTF); retinal straylight; and quality-of-vision (QoV) and spectacle-dependence questionnaires...
June 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28726651/factors-associated-with-post-stroke-fatigue-within-the-first-3-month-after-stroke
#11
I Delva, N Lytvynenko, M Delva
Aim - identify socio-demographic, personal and psychological factors associated with certain post-stroke fatigue (PSF) domains within first 3 months after stroke. There were examined patients consequently in definite time points after ischemic or hemorrhagic strokes: at hospital stay (234 patients), in 1 month (203 patients) and in 3 months (176 patients). Global PSF and certain PSF domains were measured by multidimensional fatigue inventory-20 (MFI-20) scale. In multivariate logistic regression analysis the majority of variables (gender, marital status, education level, smoking status, level of alcohol consumption, apathetic impairments, arterial hypertension, atrial fibrillation, ischemic heart disease, diabetes mellitus, body mass index, waist circumference) were not significantly associated with any PSF domain risk at any time point after stroke...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28725033/interferometric-rotating-point-spread-function
#12
Wei Wang, Guohai Situ
Rotating point spread functions (PSF), such as the double helix (DH) PSF, are widely used in localization-based super-resolution imaging because of their large working depth range. In this article, we propose an interferometric DH PSF (iDH PSF) using two opposed objective lenses as in the 4Pi microscope. In the proposed iDH PSF, the super-resolution in the axial PSF is transferred to the azimuthal rotation. Moreover, we design an iDH PSF whose imaging range reaches 3 μm, which is roughly 3 times as much as that which can be obtained by using other interferometric localization-based super-resolution imaging methods...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724348/efficacy-and-safety-of-polymer-free-stent-versus-polymer-permanent-drug-eluting-stent-in-patients-with-acute-coronary-syndrome-a-meta-analysis-of-randomized-control-trials
#13
Kang Gao, Yiguang Sun, Ming Yang, Ling Han, Liwei Chen, Wenze Hu, Ping Chen, Xiaohong Li
BACKGROUND: The efficacy and safety of polymer-free stent (PFS) versus permanent polymer drug-eluting stent (PPDES) in patients undergoing percutaneous coronary intervention (PCI) remain controversial. Our meta-analysis was undertaken to evaluate and compare the efficacy and safety of PFS with those of PPDES in patients undergoing PCI. METHODS: We searched PubMed, Cochrane Library, EMBASE, and Clinical Trials.gov databases for randomized controlled trials (RCTs)...
July 19, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28723878/evolution-of-surgery-for-adolescent-idiopathic-scoliosis-over-20-years-have-outcomes-improved
#14
Baron S Lonner, Yuan Ren, Burt Yaszay, Patrick J Cahill, Suken A Shah, Randal R Betz, Amer F Samdani, Harry L Shufflebarger, Peter O Newton
STUDY DESIGN: Retrospective review of a prospective Adolescent Idiopathic Scoliosis (AIS) registry OBJECTIVE.: To study the evolution of the operative approach, outcomes and complication rates in AIS surgery over the past 20 years. METHODS: 1819 AIS patients (1995-2013) with 2-year F/U were studied. Operative approach, perioperative parameters, major complication rates, and SRS outcomes were assessed. Linear regression was used to assess the trend of changes over 5-year quartiles...
July 18, 2017: Spine
https://www.readbyqxmd.com/read/28721202/defining-the-inflammatory-signature-of-human-lung-explant-tissue-in-the-presence-and-absence-of-glucocorticoid
#15
Tracy L Rimington, Emily Hodge, Charlotte K Billington, Sangita Bhaker, Binaya K C, Iain Kilty, Scott Jelinsky, Ian P Hall, Ian Sayers
BACKGROUND:  Airway inflammation is a feature of many respiratory diseases and there is a need for newer, more effective anti-inflammatory compounds. The aim of this study was to develop an ex vivo human lung explant model which can be used to help study the mechanisms underlying inflammatory responses and which can provide a tool to aid drug discovery for inflammatory respiratory diseases such as asthma and COPD. METHOD:  Parenchymal lung tissue from 6 individual donors was dissected and cultured with two pro-inflammatory stimuli, lipopolysaccharide (LPS) (1 µg/ml) and interleukin-1 beta (IL-1β) (10 ng/ml) in the presence or absence of dexamethasone (1 µM)...
2017: F1000Research
https://www.readbyqxmd.com/read/28719560/perioperative-and-delayed-major-complications-following-surgical-treatment-of-adolescent-idiopathic-scoliosis
#16
Carrie E Bartley, Burt Yaszay, Tracey P Bastrom, Suken A Shah, Baron S Lonner, Jahangir Asghar, Firoz Miyanji, Amer Samdani, Peter O Newton
BACKGROUND: Reporting accurate surgical complication rates to patients and their families is important in the management of adolescent idiopathic scoliosis (AIS). In this study, we report the rate of major complications following the surgical treatment of AIS both in the perioperative period and among patients with a minimum of 2 years of follow-up. METHODS: We reviewed the prospectively collected data of a multicenter registry of patients who underwent surgical treatment of AIS during the period of 1995 to 2014 in order to identify all complications...
July 19, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28713589/super-resolution-imaging-in-a-multiple-layer-epid
#17
Haijian Chen, Joerg Rottmann, Stephen Sf Yip, Daniel Morf, Rony Füglistaller, Josh Star-Lack, George Zentai, Ross Berbeco
A new portal imager consisting of four vertically stacked conventional electronic portal imaging device (EPID) layers has been constructed in pursuit of improved detective quantum efficiency (DQE). We hypothesize that super-resolution (SR) imaging can also be achieved in such a system by shifting each layer laterally by half a pixel relative to the layer above. Super-resolution imaging will improve resolution and contrast-to-noise ratio (CNR) in megavoltage (MV) planar and cone beam computed tomography (MV-CBCT) applications...
April 2017: Biomedical Physics & Engineering Express
https://www.readbyqxmd.com/read/28713087/clinical-factors-related-to-post-stroke-fatigue-within-the-first-3-month-after-acute-cerebrovascular-events
#18
Iryna I Delva, Mykhaylo Y Delva, Volodymyr A Poltorapavlov
INTRODUCTION: Post-stroke fatigue (PSF) is a common stroke complication with long-term negative consequences. AIM: Assess the rates of certain PSF domains within first 3 months after different acute cerebrovascular events (ACE) and identify clinical factors associated with each PSF domain. MATERIAL AND METHODS: There were examined 285 patients (195 with ischemic strokes, 39 with hemorrhagic strokes and 51 with transient ischemic attacks (TIA)) consequently at hospital stay, in 1 month and in 3 months after ACE...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28687866/quantification-improvement-and-harmonization-of-small-lesion-detection-with-state-of-the-art-pet
#19
REVIEW
Charlotte S van der Vos, Daniëlle Koopman, Sjoerd Rijnsdorp, Albert J Arends, Ronald Boellaard, Jorn A van Dalen, Mark Lubberink, Antoon T M Willemsen, Eric P Visser
In recent years, there have been multiple advances in positron emission tomography/computed tomography (PET/CT) that improve cancer imaging. The present generation of PET/CT scanners introduces new hardware, software, and acquisition methods. This review describes these new developments, which include time-of-flight (TOF), point-spread-function (PSF), maximum-a-posteriori (MAP) based reconstruction, smaller voxels, respiratory gating, metal artefact reduction, and administration of quadratic weight-dependent (18)F-fluorodeoxyglucose (FDG) activity...
August 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28676945/verification-of-the-tumor-volume-delineation-method-using-a-fixed-threshold-of-peak-standardized-uptake-value
#20
Kazuya Koyama, Takuya Mitsumoto, Takahiro Shiraishi, Keisuke Tsuda, Atsushi Nishiyama, Kazumasa Inoue, Kyosan Yoshikawa, Kazuo Hatano, Kazuo Kubota, Masahiro Fukushi
We aimed to determine the difference in tumor volume associated with the reconstruction model in positron-emission tomography (PET). To reduce the influence of the reconstruction model, we suggested a method to measure the tumor volume using the relative threshold method with a fixed threshold based on peak standardized uptake value (SUVpeak). The efficacy of our method was verified using (18)F-2-fluoro-2-deoxy-D-glucose PET/computed tomography images of 20 patients with lung cancer. The tumor volume was determined using the relative threshold method with a fixed threshold based on the SUVpeak...
July 4, 2017: Radiological Physics and Technology
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