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Coronary artery calcium OR intima media thickness AND Neck

Olha V Skochko, Igor P Kaidashev
INTRODUCTION: Pioglitazone, a medication of thiazolidinedione group, is capable of triggering the peroxisome proliferator-activated receptors (PPAR-γ). Activation of receptor PPAR-γ regulates carbohydrate and lipid metabolism, immune and inflammatory responses in heart tissues. THE AIM: Our aim was to study the effect of pioglitazone on insulin resistance, the clinical course of atherosclerosis and coronary heart disease (CHD). MATERIALS AND METHODS: The study included 43 patients with coronary artery disease...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Rong-Jiang Zou, Zheng-Hua Wang, Chen-Xi Wang, Song Xue
BACKGROUND: The autologous saphenous vein is the most common conduit for coronary artery bypass grafting, but the vein graft disease will occur. This study used Matrigel basement membrane matrix with many different growth factors to promote vasa vasorum neovascularization and extenuate the hypoxia to improve remodeling. METHODS: This study observed the hypoxia and thickness of the vein grafts at different times. Normal veins and vein grafts with 15 min of ischemia one day postoperatively were harvested in the neck of rabbits...
June 5, 2017: Chinese Medical Journal
C P Baena, P A Lotufo, I S Santos, A C Goulart, M S Bittencourt, B B Duncan, S Liu, I M Benseñor
BACKGROUND AND AIMS: It is uncertain whether neck circumference can be a risk indicator for subclinical atherosclerosis. We aimed to investigate their relationships measured by coronary artery calcium (CAC) and common carotid intima-media thickness (cc-IMT) with neck circumference in ELSA-Brasil. METHODS AND RESULTS: In cross-sectional and sex-specific analyses of 2266 women (50.6 ± 8.4 yrs) and 1886 men (50.7 ± 9.0 yrs) with both cc-IMT and CAC, free from previous cardiovascular disease at baseline, we built logistic models using diverse cut-off points for CAC score (0 vs > 0, < 100 vs ≥ 100, < 400 vs ≥ 400 Agatston units) and cc-IMT (< 75 th percentile vs ≥ 75 th; <90th percentile vs ≥ 90 th) as dependent variables, after which adjustments for age and traditional cardiovascular risk factors were made...
March 2016: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
Yashashwi Pokharel, Francisco Y Macedo, Vijay Nambi, Seth S Martin, Khurram Nasir, Nathan D Wong, Jeffrey Boone, Arthur J Roberts, Christie M Ballantyne, Salim S Virani
BACKGROUND: Neck circumference (NC) is associated with metabolic syndrome (MetS) in the general population. It is not known if NC is associated with MetS and subclinical atherosclerosis in retired National Football League (NFL) players. HYPOTHESIS: We hypothesized that NC is associated with MetS and subclinical atherosclerosis (assessed as coronary artery calcium [CAC] and carotid artery plaque [CAP]) in retired NFL players. METHODS: NC was measured midway between the midcervical spine and midanterior neck in 845 retired NFL players...
July 2014: Clinical Cardiology
Henrik Sillesen, Pieter Muntendam, Aram Adourian, Robert Entrekin, Mario Garcia, Erling Falk, Valentin Fuster
OBJECTIVES: The purpose of this study was to compare carotid plaque burden, carotid intima-media thickness (cIMT), ankle-brachial index (ABI), and abdominal aortic diameter (AAD) to coronary artery calcium score (CACS) in people without known cardiovascular disease. BACKGROUND: The clinical utility of risk factors to predict cardiovascular events is limited. Detection of subclinical atherosclerosis by noninvasive tests such as CACS, cIMT, carotid plaque burden, AAD, and ABI may improve risk prediction above that of established risk scoring models, namely, Framingham Risk Score...
July 2012: JACC. Cardiovascular Imaging
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