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https://www.readbyqxmd.com/read/28646492/prenatal-perinatal-and-neonatal-risk-factors-for-perinatal-arterial-ischaemic-stroke-a-systematic-review-and-meta-analysis
#1
REVIEW
C Li, J K Miao, Y Xu, Y Y Hua, Q Ma, L L Zhou, H J Liu, Q X Chen
The aim of the present study was to perform a meta-analysis of published data to determine the significance of clinical factors and exposures to the risk of perinatal arterial ischaemic stroke (PAIS) and provide guidance for clinical diagnosis and treatment. A comprehensive literature search of the PubMed, Embase, MEDLINE and Cochrane Library databases for relevant observational studies (cohort/case-control) from March 1984 to March 2016 was undertaken. Two review authors independently examined the full text records to determine which studies met the inclusion criteria and evaluated risk factors for PAIS...
June 24, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28646142/efficacy-and-safety-of-tenofovir-disoproxil-fumarate-in-preventing-vertical-transmission-of-hepatitis-b-in-pregnancies-with-high-viral-load
#2
Jun-Ze Chen, Zuo-Wei Liao, Fei-Long Huang, Ru-Kui Su, Wen-Bo Wang, Xue-Yuan Cheng, Jie-Qing Chen, Jia-Qi Liu, Zhong Huang
This study was a meta-analysis of the literature on the efficacy and safety of tenofovir disoproxil fumarate (TDF) in preventing vertical transmission of hepatitis B in pregnancies with high viral load. Four observational studies and one randomized controlled trial involving 585 pregnant women and 595 newborns were included in the meta-analysis. TDF was more effective than the placebo in reducing vertical transmission in HBeAg-positive chronic hepatitis B (CHB) pregnancies with high serum HBV-DNA levels (OR = 0...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28639253/ultrasonography-in-trauma-a-nation-wide-cross-sectional-investigation
#3
Jesper Weile, Klaus Nielsen, Stine C Primdahl, Christian A Frederiksen, Christian B Laursen, Erik Sloth, Hans Kirkegaard
BACKGROUND: The Focused Assessment with Sonography in Trauma (FAST) protocol is considered beneficial in emergent evaluation of trauma patients with blunt or penetrating injury and has become integrated into the Advanced Trauma Life Support (ATLS) protocol. No guidelines exist as to the use of ultrasonography in trauma in Denmark. We aimed to determine the current use of ultrasonography for assessing trauma patients in Denmark. METHODS: We conducted a nation-wide cross-sectional investigation of ultrasonography usage in trauma care...
December 2017: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/28638896/a-scalable-cyberinfrastructure-for-interactive-visualization-of-terascale-microscopy-data
#4
A Venkat, C Christensen, A Gyulassy, B Summa, F Federer, A Angelucci, V Pascucci
The goal of the recently emerged field of connectomics is to generate a wiring diagram of the brain at different scales. To identify brain circuitry, neuroscientists use specialized microscopes to perform multichannel imaging of labeled neurons at a very high resolution. CLARITY tissue clearing allows imaging labeled circuits through entire tissue blocks, without the need for tissue sectioning and section-to-section alignment. Imaging the large and complex non-human primate brain with sufficient resolution to identify and disambiguate between axons, in particular, produces massive data, creating great computational challenges to the study of neural circuits...
August 2016: N Y Sci Data Summit NYSDS
https://www.readbyqxmd.com/read/28637644/does-attendance-at-a-specialist-antenatal-clinic-improve-clinical-outcomes-in-women-with-class-iii-obesity-compared-with-standard-care-a-retrospective-case-note-analysis
#5
Fiona C Denison, Heather MacGregor, Laura I Stirrat, Kerrie Stevenson, Jane E Norman, Rebecca M Reynolds
OBJECTIVES: To determine whether attendance at a specialised multidisciplinary antenatal clinic for women with class III obesity (BMI >40 kg/m(2)) is associated with improved clinical outcomes compared with standard antenatal care. DESIGN: Retrospective cohort study using routinely collected data from electronic patient record. SETTING: Community and hospital based antenatal care. PARTICIPANTS: Women with a singleton pregnancy with class III obesity booked for antenatal care and delivered in one of two hospitals in NHS Lothian, Scotland, UK between 2008 and 2014...
June 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28632918/predicting-inpatient-hypoglycaemia-in-hospitalized-patients-with-diabetes-a-retrospective-analysis-of-9584-admissions-with-diabetes
#6
K Stuart, N J Adderley, T Marshall, G Rayman, A Sitch, S Manley, S Ghosh, K A Toulis, K Nirantharakumar
AIMS: To explore whether a quantitative approach to identifying hospitalized patients with diabetes at risk of hypoglycaemia would be feasible through incorporation of routine biochemical, haematological and prescription data. METHODS: A retrospective cross-sectional analysis of all diabetic admissions (n=9584) from 1 January 2014 to 31 December 2014 was performed. Hypoglycaemia was defined as a blood glucose level of <4 mmol/l. The prediction model was constructed using multivariable logistic regression, populated by clinically important variables and routine laboratory data...
June 20, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28631513/the-effect-of-labour-pain-in-caesarean-delivery-on-neonatal-and-maternal-outcomes-in-a-term-low-risk-obstetric-population
#7
Meryem Kurek Eken, Gülçin Şahin Ersoy, Sinem Çetinkaya, Çetin Çam, Ateş Karateke
Planned caesarean delivery (CD) frequency is increasing in many countries, and elective CD accounts for 50% of preventable causes of neonatal respiratory morbidity. The clearing of fluid in the lungs is important for the establishment of normal gas exchange with inspired air. A defect in this clearance can result in respiratory problems in neonate, but on the other hand patients waiting for the onset of spontaneous labour pain, the increase in emergency CD, together with severe mortality and morbidity are causes of concern and cause anxiety and distrust of obstetricians...
June 20, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28630744/maternal-predictors-of-neonatal-outcomes-after-emergency-cesarean-section-a-retrospective-study-in-three-rural-district-hospitals-in-rwanda
#8
Naome Nyirahabimana, Christine Minani Ufashingabire, Yihan Lin, Bethany Hedt-Gauthier, Robert Riviello, Jackline Odhiambo, Joel Mubiligi, Martin Macharia, Stephen Rulisa, Illuminee Uwicyeza, Patient Ngamije, Fulgence Nkikabahizi, Theoneste Nkurunziza
BACKGROUND: In sub-Saharan Africa, neonatal mortality post-cesarean delivery is higher than the global average. In this region, most emergency cesarean sections are performed at district hospitals. This study assesses maternal predictors for poor neonatal outcomes post-emergency cesarean delivery in three rural district hospitals in Rwanda. METHODS: This retrospective study includes a random sample of 441 neonates from Butaro, Kirehe and Rwinkwavu District Hospitals, born between 01 January and 31 December 2015...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/28612643/survey-of-irish-general-practitioners-preferences-for-continuing-professional-development
#9
B Maher, R O'Neill, A Faruqui, C Bergin, M Horgan, D Bennett, C M P O'Tuathaigh
BACKGROUND: Doctors' continuing professional development (CPD) training needs are known to be strongly influenced by national and local contextual characteristics. Given the changing national demographic profile and government-mandated changes to primary care health care provision, this study aimed to investigate Irish General Practitioners' (GPs) perceptions of, and preferences for, current and future CPD programmes. METHODS: A cross-sectional questionnaire, using closed- and open-ended questions, was administered to Irish GPs, focusing on training needs analysis; CPD course content; preferred format and the learning environment...
June 14, 2017: Education for Primary Care
https://www.readbyqxmd.com/read/28606747/hot-tea-and-tiny-tots-don-t-mix-a-cross-sectional-survey-on-hot-beverage-scalds
#10
J D Burgess, R M Kimble, K A Watt, C M Cameron
OBJECTIVE: Hot beverage scalds are a leading cause of burns in young children. The aim of this study was to look at the circumstances surrounding these injuries in terms of setting, mechanism, supervision and first aid to inform a prevention campaign. METHODS: A cross-sectional study was delivered via iPad to parents and caregivers presenting with a child aged 0-36 months with a hot beverage scald at a major paediatric burns centre. RESULTS: Of the 101 children aged 0-36 months that presented with a hot beverage scald over a 12-month period, 54 participants were included...
June 9, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28606491/cesarean-section-and-risk-of-postpartum-depression-a-meta-analysis
#11
REVIEW
Hui Xu, Yu Ding, Yue Ma, Xueling Xin, Dongfeng Zhang
OBJECTIVE: The association of cesarean section (CS) with the risk of postpartum depression (PPD) remains controversial. Therefore, we conducted a meta-analysis to explore the association between CS and the risk of PPD. METHODS: A systematic literature search was performed in PubMed, Web of Science and Embase databases for relevant articles up to November 2016. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated with fixed-effects model or random-effects model...
June 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28604147/nak-alloy-induced-in-vivo-tumor-ablation-therapy
#12
Wei Wang, Ying Liu, Huan Liu, Yonghui An, Qian Wang, Jing Liu
PURPOSE: Alkali metal ablation is newly emerging as an effective, economic and minimally invasive ablation therapy. This study is dedicated to demonstrate the high efficiency of NaK alloy ablation on in vivo tumors with different stages in mice. MATERIAL AND METHODS: Panc02 tumor cells were injected into 21 female C57B/L mice, which were divided into three groups. Two experimental groups of mice received the same percutaneous NaK alloy injection for a week apart...
June 12, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28599396/five-years-experience-in-an-anesthesiology-antenatal-clinic-for-high-risk-patients
#13
Daniel Shatalin, Yaacov Gozal, Sorina Grisaru-Granovsky, Alexander Ioscovich
INTRODUCTION: The aim, of this study is to describe our approach and outcomes in an outpatient anesthesia/analgesia antepartum clinic among ambulatory high-risk obstetric patients. METHODS: This was a retrospective evaluation of the activity of the anesthesiology antenatal clinic from its inception in 2010 until 2016 (a 5-year period). The clinic works in collaboration with the Department of Obstetrics and Gynecology. The catchment area of the study University Affiliated Hospital attends a multiethnic population characterized by high parity...
May 24, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28598496/introduction-to-the-special-section%C3%A2-of-child-development-on-positive-youth-development-in-diverse-and-global-contexts
#14
Patrick J Leman, Emilie P Smith, Anne C Petersen
Positive youth development (PYD) research seeks to understand and promote positive aspects of development in young people. In this the special section, focused upon youth from diverse racial-ethnic backgrounds around the globe, we describe the origins and development of the field, identify key and emerging themes, and present the challenges for work in the area in the years ahead. Central to these are elements that are inherent in many of the articles that constitute the section: These include a need to articulate more clearly the role of social and cultural context in positive development, a need to refine the measures and methods used for collecting data, the significance of social identities, and engagement with other fields of study and with policymakers...
June 9, 2017: Child Development
https://www.readbyqxmd.com/read/28595824/zika-in-the-americas-year-2-what-have-we-learned-what-gaps-remain-a-report-from-the-global-virus-network
#15
REVIEW
Matthew T Aliota, Leda Bassit, Shelton S Bradrick, Bryan Cox, Mariano A Garcia-Blanco, Christina Gavegnano, Thomas C Friedrich, Thaddeus G Golos, Diane E Griffin, Andrew Haddow, Esper G Kallas, Uriel Kitron, Marc Lecuit, Diogo M Magnani, Caroline Marrs, Natalia Mercer, Edward McSweegan, Lisa Ng, David H O'Connor, Jorge E Osorio, Guilherme S Ribeiro, Michael Ricciardi, Shannan L Rossi, George Saade, Raymond F Schinazi, Geraldine O Schott-Lerner, Chao Shan, Pei-Yong Shi, David I Watkins, Nikos Vasilakis, Scott C Weaver
In response to the outbreak of Zika virus (ZIKV) infection in the Western Hemisphere and the recognition of a causal association with fetal malformations, the Global Virus Network (GVN) assembled an international taskforce of virologists to promote basic research, recommend public health measures and encourage the rapid development of vaccines, antiviral therapies and new diagnostic tests. In this article, taskforce members and other experts review what has been learned about ZIKV disease in humans, its modes of transmission and the cause and nature of associated congenital manifestations...
June 5, 2017: Antiviral Research
https://www.readbyqxmd.com/read/28594099/cerebroplacental-ratio-thresholds-measured-within-two-weeks-of-birth-and-the-risk-of-cesarean-section-for-intrapartum-fetal-compromise-and-adverse-neonatal-outcome
#16
Larissa N Bligh, Amal A Alsolai, Ristan M Greer, Sailesh Kumar
OBJECTIVES: Prediction of intrapartum fetal compromise in uncomplicated, term pregnancies is a global obstetric challenge. Currently, no widely accepted screening test for this condition exists, although the cerebroplacental ratio (CPR) shows promise. We aimed to prospectively evaluate the screening performance of the CPR 10(th) centile for detection of Cesarean section for intrapartum fetal compromise (IFC) and composite adverse neonatal outcome (ANO) in low-risk women from 36 weeks and to determine the best CPR threshold from three previously described in the literature...
June 8, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28589923/electronic-properties-and-morphology-of-copper-oxide-n-type-silicon-heterostructures
#17
Per Lindberg, Sandeep Gorantla, Anette Gunnaes, Bengt Svensson, Edouard V Monakhov
Silicon-based tandem heterojunction solar cells utilizing cuprous oxide (Cu<sub>2</sub>O) as the top absorber layer show promise for high-efficiency conversion and low production cost. In the present study, single phase Cu<sub>2</sub>O films have been realized on n-type Si substrates by reactive magnetron sputtering at 400<sup>o</sup>C. The obtained Cu<sub>2</sub>O/Si heterostructures have subsequently been heat treated at temperatures in the 400-700<sup>o</sup>C range in Ar flow and extensively characterized by X-ray diffraction (XRD) measurements, transmission electron microscopy (TEM) imaging and electrical techniques...
June 7, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28589479/risk-factors-for-incomplete-healing-of-the-uterine-incision-after-cesarean-section
#18
Yan Chen, Ping Han, Yi-Jia Wang, Yan-Xia Li
OBJECTIVE: To analyze related risk factors of post-cesarean scar defects (PCSDs). METHODS: A retrospective study of full-term women delivered by cesarean with singleton infants at our hospital from April 2014 to December 2015 was performed. 69 cases of diagnosed PCSDs and 107 cases with no PCSD who accepted cesarean were recruited for analysis. Individual medical case and operative report review were retrieved for maternal clinical characteristics analysis. RESULTS: There was no difference in age, gestational age, BMI and baby's weight between the two groups...
June 6, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28587344/acquired-uterine-arteriovenous-fistula-due-to-a-previous-cornual-pregnancy-with-placenta-accreta-a-case-report
#19
Dongdong Guan, Jie Wang, Liju Zong, Shan Li, You-Zhong Zhang
The present report describes a case of an acquired uterine arteriovenous fistula, which, following surgery and postoperative pathological analysis, was confirmed as a previous cornual pregnancy with placenta accreta. The patient was a 37-year-old woman (gravida 3; para 2) who had previously delivered two children via cesarean section (in 2004 and 2010, respectively) and also had a spontaneous abortion (2008). She had experienced continuous menstrual bleeding for ~20 days and had a history of prolonged (~30 days) vaginal bleeding 13 months earlier...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28585791/-pediatric-traumatic-brain-injury-due-to-civil-gunshot-wounds-at-a-general-hospital-in-cali-colombia
#20
L Parrado Sánchez, C Gómez, J A Valderrama Chaparro, L D Beltrán Osorio, M Sierra Ruiz, A Enríquez Marulanda, J Lobato Polo
OBJECTIVES: Traumatic brain injury (TBI) due to gunshot-wounds (GSW) is a critical situation in the pediatric population. The aim of this study is to characterize TBI in this population since there are few reports that describe it especially in Colombia where its incidence is high, also to determine which were the main mortality predictor within our population. MATERIAL AND METHODS: We conducted a retrospective cross-sectional study in which we reviewed pediatric medical records of patients that had consulted at the Fundacion Valle del Lili pediatric Emergency Room between January of 2011 and December of 2015 because of TBI due to GSW...
January 25, 2017: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
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