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https://www.readbyqxmd.com/read/29443421/diabetes-uk-evidence-based-nutrition-guidelines-for-the-prevention-and-management-of-diabetes
#1
P A Dyson, D Twenefour, C Breen, A Duncan, E Elvin, L Goff, A Hill, P Kalsi, N Marsland, P McCardle, D Mellor, L Oliver, K Watson
A summary of the latest evidence-based nutrition guidelines for the prevention and management of diabetes is presented. These guidelines are based on existing recommendations last published in 2011, and were formulated by an expert panel of specialist dietitians after a literature review of recent evidence. Recommendations have been made in terms of foods rather than nutrients wherever possible. Guidelines for education and care delivery, prevention of Type 2 diabetes, glycaemic control for Type 1 and Type 2 diabetes, cardiovascular disease risk management, management of diabetes-related complications, other considerations including comorbidities, nutrition support, pregnancy and lactation, eating disorders, micronutrients, food supplements, functional foods, commercial diabetic foods and nutritive and non-nutritive sweeteners are included...
February 14, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29437883/cerebrospinal-fluid-reference-values-for-young-infants-undergoing-lumbar-puncture
#2
Joanna Thomson, Heidi Sucharew, Andrea T Cruz, Lise E Nigrovic, Stephen B Freedman, Aris C Garro, Fran Balamuth, Rakesh D Mistry, Joseph L Arms, Paul T Ishimine, Dina M Kulik, Mark I Neuman, Samir S Shah
OBJECTIVES: To determine age-specific reference values and quantify age-related changes for cerebrospinal fluid (CSF) white blood cell (WBC) counts and protein and glucose concentrations in infants ≤60 days of age. METHODS: This multicenter, cross-sectional study included infants ≤60 days old with CSF cultures and complete CSF profiles obtained within 24 hours of presentation. Those with conditions suspected or known to cause abnormal CSF parameters (eg, meningitis) and those with a hospital length of stay of >72 hours were excluded...
February 2, 2018: Pediatrics
https://www.readbyqxmd.com/read/29435451/umbilical-hernia-repair-and-pregnancy-before-during-after%C3%A2
#3
REVIEW
Hakan Kulacoglu
Umbilical hernias are most common in women than men. Pregnancy may cause herniation or render a preexisting one apparent, because of progressively raised intra-abdominal pressure. The incidence of umbilical hernia among pregnancies is 0.08%. Surgical algorithm for a pregnant woman with a hernia is not thoroughly clear. There is no consensus about the timing of surgery for an umbilical hernia in a woman either who is already pregnant or planning a pregnancy. If the hernia is incarcerated or strangulated at the time of diagnosis, an emergency repair is inevitable...
2018: Frontiers in Surgery
https://www.readbyqxmd.com/read/29432202/plasma-midregional-proadrenomedullin-mr-proadm-concentrations-and-their-biological-determinants-in-a-reference-population
#4
Magdalena Krintus, Marek Kozinski, Federica Braga, Jacek Kubica, Grazyna Sypniewska, Mauro Panteghini
BACKGROUND: Midregional proadrenomedullin (MR-proADM) is emerging as a prognostic biomarker for detecting the failure of multiple organs. Establishment of scientifically robust reference intervals facilitates interpretation of laboratory test results. The objectives of this study were (i) to establish reliable reference intervals for plasma MR-proADM using a commercially available automated fluoroimmunoassay in apparently healthy individuals, and (ii) to identify biological determinants of MR-proADM concentrations...
February 13, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29430646/internationally-educated-nurses-in-canada-perceived-benefits-of-bridging-programme-participation
#5
C L Covell, M D Primeau, I St-Pierre
AIM: To examine internationally educated nurses' perceptions of the extent to which participating in bridging programmes is beneficial for preparing to practise nursing in Canada. BACKGROUND: Internationally educated nurses continue to migrate from low-income to high-income countries. Many experience challenges when attempting to practise their profession in the destination country. Canada and other top destination countries offer educational support, such as bridging programmes, to assist internationally educated nurses' with preparing to practise nursing in the destination country...
February 12, 2018: International Nursing Review
https://www.readbyqxmd.com/read/29430166/riemannian-nonlinear-mixed-effects-models-analyzing-longitudinal-deformations-in-neuroimaging
#6
Hyunwoo J Kim, Nagesh Adluru, Heemanshu Suri, Baba C Vemuri, Sterling C Johnson, Vikas Singh
Statistical machine learning models that operate on manifold-valued data are being extensively studied in vision, motivated by applications in activity recognition, feature tracking and medical imaging. While non-parametric methods have been relatively well studied in the literature, efficient formulations for parametric models (which may offer benefits in small sample size regimes) have only emerged recently. So far, manifold-valued regression models (such as geodesic regression) are restricted to the analysis of cross-sectional data, i...
July 2017: Proceedings
https://www.readbyqxmd.com/read/29429201/-survey-on-the-prevalence-of-continuous-blood-purification-in-chinese-pediatric-critical-care
#7
X Yang, S Y Qian, Y M Zhu, X Xu, C F Liu, F Xu, X X Ren, Y Wang, Y C Zhang, G P Lu
Objective: To investigate the current application status of continuous blood purification (CBP) technology and equipment in pediatric intensive care unit (PICU) in China. Methods: A cross-sectional survey was conducted to understand the current popularization of CBP technology and equipment, the management of CBP equipment and consumables, and the application of CBP in different diseases. A questionnaire named Application Status of Continuous Blood Purification Technology was applied. Children's hospitals and polyclinic hospitals with the pediatric qualification (pediatric emergency or critical care unit members of Chinese Medical Association and Chinese Medical Doctor Association) were selected...
February 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29427801/escmid-study-group-for-infections-in-compromised-hosts-esgich-consensus-document-on-the-safety-of-targeted-and-biological-therapies-an-infectious-diseases-perspective-introduction
#8
REVIEW
Mario Fernández-Ruiz, Yolanda Meije, Oriol Manuel, Hamdi Akan, Jordi Carratalà, José María Aguado, Julie Delaloye
BACKGROUND: The field of new biological agents is increasing exponentially over the past years, thus making prevention and management of associated infectious complications a challenge for non-specialized clinicians. AIMS: The present Consensus Document is an initiative of the ESCMID Study Group for Infections in Compromised Hosts (ESGICH) aimed at analyzing, from an Infectious Diseases perspective, the safety of targeted and biological therapies. SOURCES: Computer-based MEDLINE searches with MeSH terms pertaining to each agent or therapeutic family...
February 7, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29427111/towards-the-identification-of-molecular-biomarkers-of-spinocerebellar-ataxia-type-3-sca3-machado-joseph-disease-mjd
#9
Manuela Lima, Mafalda Raposo
Whereas spinocerebellar ataxia type 3 (SCA3)/Machado-Joseph disease (MJD) remains an untreatable disorder, disease-modifying compounds have begun being tested in the context of clinical trials; their success is dependent on the sensitivity of the methods used to measure subtle therapeutic benefits. Thus, efforts are being made to propose a battery of potential outcome measures, including molecular biomarkers (MBs), which remain to be identified; MBs are particularly pertinent if SCA3 trials are expected to enroll preataxic subjects...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29426298/albuminuria-serum-creatinine-and-estimated-glomerular-filtration-rate-as-predictors-of-cardio-renal-outcomes-in-patients-with-type-2-diabetes-mellitus-and-kidney-disease-a-systematic-literature-review
#10
Keith C Norris, Karen E Smoyer, Catherine Rolland, Jan Van der Vaart, Eliza Beth Grubb
BACKGROUND: Albuminuria, elevated serum creatinine and low estimated glomerular filtration rate (eGFR) are pivotal indicators of kidney decline. Yet, it is uncertain if these and emerging biomarkers such as uric acid represent independent predictors of kidney disease progression or subsequent outcomes among individuals with type 2 diabetes mellitus (T2DM). This study systematically examined the available literature documenting the role of albuminuria, serum creatinine, eGFR, and uric acid in predicting kidney disease progression and cardio-renal outcomes in persons with T2DM...
February 9, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29424894/twist2-and-cd24-expression-alters-renal-microenvironment-in-obesity-associated-kidney-cancer
#11
X-F Yang, G Ma, N-H Feng, D-S Yu, Y Wu, C Li
OBJECTIVE: Obesity emerged as a major public health problem worldwide, and prolonged condition with increased BMI causes various metabolic disorders include the development of kidney cancer. The metabolic changes alter the renal microenvironment and thereby promoting tumor. Hence, detailed studies of genes that regulate these this changes are keen to understand. MATERIALS AND METHODS: Initially, we successfully initiate kidney tumor using prolonged intake of a high-fat diet in Wistar rats, which are confirmed with pathological changes observed through histological sectioning...
January 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29417146/associations-of-distance-to-trauma-care-community-income-and-neighborhood-median-age-with-rates-of-injury-mortality
#12
Molly P Jarman, Frank C Curriero, Elliott R Haut, Keshia Pollack Porter, Renan C Castillo
Importance: Rural, low-income, and historically underrepresented minority communities face substantial barriers to trauma care and experience high injury incidence and mortality rates. Characteristics of injury incident locations may contribute to poor injury outcomes. Objective: To examine the association of injury scene characteristics with injury mortality. Design, Setting, and Participants: In this cross-sectional study, data from trauma center and emergency medical services provided by emergency medical services companies and designated trauma centers in the state of Maryland from January 1, 2015, to December 31, 2015, were geocoded by injury incident locations and linked with injury scene characteristics...
February 7, 2018: JAMA Surgery
https://www.readbyqxmd.com/read/29415589/late-preterm-birth-and-previous-cesarean-section-a-population-based-cohort-study
#13
Abdool S Yasseen, Kate Bassil, Ann Sprague, Marcelo Urquia, Jonathon L Maguire
BACKGROUND: Late preterm birth (LPB) is increasingly common and associated with higher morbidity and mortality than term birth. Yet, little is known about the influence of previous cesarean section (PCS) and the occurrence of LPB in subsequent pregnancies. We aim to evaluate this association along with the potential mediation by cesarean sections in the current pregnancy. METHODS: We use population based birth registry data (2005-2012) to establish a cohort of live born singleton infants born between 34 and 41 gestational weeks to multiparous mothers...
February 7, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29411254/challenges-faced-by-family-physicians-providing-advanced-maternity-care
#14
Aimee R Eden, Lars E Peterson
Introduction Maldistribution of maternity care (MC) providers in the U.S. limits access to full spectrum MC services. Obstetricians are concentrated in urban areas with many rural areas reliant on family physicians (FP) to provide MC, yet fewer FPs are providing MC. The objective of this study was to understand the challenges FPs face in gaining skills in and providing advanced MC. Methods We conducted qualitative semi-structured interviews with 51 purposively sampled key stakeholders in family medicine MC (21 family medicine-OB fellowship directors, 19 past fellows, and 10 family medicine residency directors of programs with advanced MC training)...
February 6, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29408749/comparison-of-maternal-and-neonatal-outcomes-for-patients-with-placenta-accreta-spectrum-between-online-to-offline-management-model-with-standard-care-model
#15
Wen Sun, Lin Yu, Shiliang Liu, Yanhong Chen, Juanjuan Chen, Shi Wu Wen, Dunjin Chen
OBJECTIVE: Online-to-offline is a new model for emergent medical service with the ability to connect care providers with patients on instant basis. This study aims to evaluate maternal and neonatal outcomes in patients with placenta accreta spectrum managed by an online-to-offline care model. METHODS: Starting from January 1, 2015, management of patients with placenta accreta spectrum was changed from standard care model into an online-to-offline care model through "Wechat" in Guangzhou Medical Centre for Critical Obstetrical Care...
February 2, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29406837/optimization-of-medication-use-at-accountable-care-organizations
#16
Chrisanne Wilks, Erik Krisle, Kimberly Westrich, Kristina Lunner, David Muhlestein, Robert Dubois
BACKGROUND: Optimized medication use involves the effective use of medications for better outcomes, improved patient experience, and lower costs. Few studies systematically gather data on the actions accountable care organizations (ACOs) have taken to optimize medication use. OBJECTIVES: To (a) assess how ACOs optimize medication use; (b) establish an association between efforts to optimize medication use and achievement on financial and quality metrics; (c) identify organizational factors that correlate with optimized medication use; and (d) identify barriers to optimized medication use...
May 30, 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29397441/evaluation-of-cesarean-scar-after-single-and-double-layer-hysterotomy-closure-a-prospective-cross-sectional-study
#17
Nur Betül Tekiner, Berna Aslan Çetin, Lale Susan Türkgeldi, Gökçe Yılmaz, İbrahim Polat, Ali Gedikbaşı
BACKGROUND: We aimed to determine if there is a difference in the size of the cesarean scar defect using saline infusion sonography (SIS) performed on the postoperative third month in patients who underwent single- or double-layered unlocked closure of their uterine incision during their first cesarean delivery. METHODS: This study was conducted as a prospective cross-sectional study between February 2015 and January 2016 in patients admitted to the labour ward of the Kanuni Sultan Suleyman Training and Research Hospital who subsequently underwent their first delivery by cesarean section...
February 3, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29394977/bladder-distension-as-a-cause-of-abdominal-compartment-syndrome
#18
Muhammad Yasir, Muhammad Qamarul Hoda, Tauseef Ahmed
Abdominal compartment syndrome (ACS) is increasingly identified in critically ill patient and its harmful effects are well documented. The disparity among the pressure, volume in abdominal cavity and its contents, results in ACS. The actual incidence of ACS is not known. However, it has been observed predominantly in patients with severe blunt and penetrating abdominal trauma, ruptured abdominal aortic aneurysms, retro- and intra-peritoneal hemorrhage, pneumoperitoneum, neoplasm, pancreatitis, ascites and multiple bone fracture...
February 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29392073/transverse-cervicothoracic-stabbing-multidisciplinary-management-of-a-surgical-emergency
#19
Elena Molina Fernández, Ramón Moreno-Luna, Francisco López Navas, Marta López Porras, C Giménez, Serafín Sánchez Gómez
Tracheobronchial injuries are closely related to orotracheal intubations and chest traumas. Stabbing injuries are very rare and often life threatening because of the damage to vital structures such as the respiratory tract and large arterial or venous vessels. Early diagnosis and treatment of penetrating neck injuries increase survival rates. We report a case of the tracheobronchial section with a penetrating stabbing wound on the left laterocervical area associated with contralateral pneumothorax, requiring urgent surgical pulmonary repair, tracheal suture, and tracheotomy...
September 2017: Turkish Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29390596/novel-urinary-biomarkers-and-their-association-with-urinary-heavy-metals-in-chronic-kidney-disease-of-unknown-aetiology-in-sri-lanka-a-pilot-study
#20
K Wanigasuriya
Introduction: Chronic kidney disease of unknown etiology (CKDu) has emerged as a significant public health problem in Sri Lanka. The role of environmental exposure to cadmium and arsenic in the aetiology of CKDu is still unclear. Identification of a panel of novel urinary biomarkers would be invaluable in the study of toxin mediated damage postulated to be the aetiology of CKDu. Objectives: The aims of this study were to evaluate the profile of novel urinary biomarkers in CKDu patients and identify any association with environmental exposure to heavy metals...
December 26, 2017: Ceylon Medical Journal
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