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Saccharomyces boulardii

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https://www.readbyqxmd.com/read/29771163/review-of-saccharomyces-boulardii-as-a-treatment-option-in-ibd
#1
Kavitha Sivananthan, Andreas Munk Petersen
CONTEXT: Review of the yeast Saccharomyces boulardii as a treatment option for the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn's disease. OBJECTIVE: IBD is caused by an inappropriate immune response to gut microbiota. Treatment options could therefore be prebiotics, probiotics, antibiotics and/or fecal transplant. In this review, we have looked at the evidence for the yeast S. boulardii as a treatment option. MATERIAL AND METHODS: Searches in PubMed and the Cochrane Library with the MeSH words 'Saccharomyces boulardii AND IBD', 'Saccharomyces boulardii AND Inflammatory Bowel Disease', 'Saccharomyces boulardii AND ulcerative colitis' and 'Saccharomyces boulardii AND Crohn's disease' gave total a total of 80 articles...
May 17, 2018: Immunopharmacology and Immunotoxicology
https://www.readbyqxmd.com/read/29762474/saccharomyces-cerevisiae-boulardii-reduces-the-deoxynivalenol-induced-alteration-of-the-intestinal-transcriptome
#2
Imourana Alassane-Kpembi, Philippe Pinton, Jean-François Hupé, Manon Neves, Yannick Lippi, Sylvie Combes, Mathieu Castex, Isabelle P Oswald
Type B trichothecene mycotoxin deoxynivalenol (DON) is one of the most frequently occurring food contaminants. By inducing trans-activation of a number of pro-inflammatory cytokines and increasing the stability of their mRNA, trichothecene can impair intestinal health. Several yeast products, especially Saccharomyces cerevisiae , have the potential for improving the enteric health of piglets, but little is known about the mechanisms by which the administration of yeast counteracts the DON-induced intestinal alterations...
May 15, 2018: Toxins
https://www.readbyqxmd.com/read/29725956/use-of-prophylactic-saccharomyces-boulardii-to-prevent-clostridium-difficile-infection-in-hospitalized-patients-a-controlled-prospective-intervention-study
#3
Jeppe West Carstensen, Mahtab Chehri, Kristian Schønning, Steen Christian Rasmussen, Jacob Anhøj, Nina Skavlan Godtfredsen, Christian Østergaard Andersen, Andreas Munk Petersen
Clostridium difficile infection (CDI) is a common complication to antibiotic use. Saccharomyces boulardii has shown effect as a prophylactic agent. We aimed to evaluate the efficacy of S. boulardii in preventing CDI in unselected hospitalized patients treated with antibiotics. We conducted a 1 year controlled prospective intervention study aiming to prescribe Sacchaflor (S. boulardii 5 × 109 , Pharmaforce ApS) twice daily to hospitalized patients treated with antibiotics. Comparable departments from three other hospitals in our region were included as controls...
May 3, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29706942/oral-administration-of-recombinant-saccharomyces-boulardii-expressing-ovalbumin-cpe-fusion-protein-induces-antibody-response-in-mice
#4
Ghasem Bagherpour, Hosnie Ghasemi, Bahare Zand, Najmeh Zarei, Farzin Roohvand, Esmat M Ardakani, Mohammad Azizi, Vahid Khalaj
Saccharomyces boulardii , a subspecies of Saccharomyces cerevisiae , is a well-known eukaryotic probiotic with many benefits for human health. In the present study, a recombinant strain of S. boulardii was prepared to use as a potential oral vaccine delivery vehicle. In this sense, a ura3 auxotroph strain of S. boulardii CNCM I-745 (known as S. cerevisiae HANSEN CBS 5926, Yomogi® ) was generated using CRISPR/Cas9 methodology. Then a gene construct encoding a highly immunogenic protein, ovalbumin (OVA), was prepared and transformed into the ura3- S...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29697280/effect-of-saccharomyces-boulardii-cell-wall-extracts-on-colon-cancer-prevention-in-male-f344-rats-treated-with-1-2-dimethylhydrazine
#5
Olivier Fortin, Blanca R Aguilar-Uscanga, Khanh D Vu, Stephane Salmieri, Monique Lacroix
The effect of Saccharomyces boulardii cell wall extracts on colon cancer prevention in rats treated with 1,2-dimethylhydrazine was investigated. A crude insoluble glucan (0.5 and 1.0 mg/kg/day) and a crude mannoprotein extract (0.3 and 3.0 mg/kg/day) were administered in rats by gavage for 12 weeks along with a high fat low fiber diet whereupon rats were sacrificed and aberrant crypt foci (ACF) were counted in the colon. Moreover, NAD(P)H: quinone reductase (QR) and harmful fecal enzymes (β-glucosidase and β-glucuronidase) were quantified in the liver and in the caecum, respectively...
May 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/29696516/isolation-of-yeasts-from-guajillo-pepper-capsicum-annuum-l-fermentation-and-study-of-some-probiotic-characteristics
#6
C E Lara-Hidalgo, L Dorantes-Álvarez, H Hernández-Sánchez, F Santoyo-Tepole, A Martínez-Torres, L Villa-Tanaca, C Hernández-Rodríguez
Three yeast strains were isolated from the spontaneous fermentation of guajillo pepper: Hanseniaspora opuntiae, Pichia kudriavzevii, and Wickerhamomyces anomalus, which were identified by amplification of the ITS/5.8S ribosomal DNA. Some probiotic characteristics of these strains were evaluated and compared with one commercial probiotic yeast (Saccharomyces boulardii). The survival percentage of all the yeasts was similar to that of the commercial product. They showed different hydrophobicity characteristics with hydrocarbons, autoaggregation > 90%, and characteristics of co-aggregation with pathogenic microorganisms...
April 25, 2018: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29580515/probiotic-potential-of-yeasts-isolated-from-pineapple-and-their-use-in-the-elaboration-of-potentially-functional-fermented-beverages
#7
Juliana Cunha Amorim, Roberta Hilsdorf Piccoli, Whasley Ferreira Duarte
Pineapple (Ananas comosus (L.) Merril) is a tropical fruit rich in nutrients characterized by a pleasant taste and widely consumed in several countries. It is used to produce juice, jams and wine. In this work, 150 yeasts isolates were obtained from peel (18) and spontaneously fermented pineapple pulp (132). The probiotic potential of 50 isolates was studied. Survival at pH 2.0, pepsin 3.0 g/L, and tolerance of bile salts (0.1 and 1% (w/v) were determined as indicators of survival potential of the isolates during the passage through the human gastrointestinal tract in simulated conditions...
May 2018: Food Research International
https://www.readbyqxmd.com/read/29544579/clinical-efficacy-comparison-of-saccharomyces-boulardii-and-lactic-acid-as-probiotics-in-acute-pediatric-diarrhea
#8
Shakila Asmat, Fouzia Shaukat, Raheela Asmat, Hafiz Faiq Siddique Gul Bakhat, Tauseef M Asmat
OBJECTIVE: To compare the efficacy of Saccharomyces boulardii and lactic acid producing probiotics in addition to usual treatment regimen to cure diarrhea among children (6 months to 5 years of age). STUDY DESIGN: Randomized controlled trial. PLACE AND DURATION OF STUDY: Department of Pediatrics, Sheikh Zayed Hospital, Lahore, from February to July 2015. METHODOLOGY: Children suffering from acute diarrhea were orally administered Saccharomyces boulardii and lactic acid producing probiotics for 5 days...
March 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29523547/a-mutation-in-pgm2-causing-inefficient-galactose-metabolism-in-the-probiotic-yeast-saccharomyces-boulardii
#9
Jing-Jing Liu, Guo-Chang Zhang, In Iok Kong, Eun Ju Yun, Jia-Qi Zheng, Dae-Hyuk Kweon, Yong-Su Jin
The probiotic yeast Saccharomyces boulardii has been extensively studied for the prevention and treatment of diarrheal diseases, and it is now commercially available in some countries. S. boulardii displays notable phenotypic characteristics, such as a high optimal growth temperature, high tolerance against acidic conditions, and the inability to form ascospores, which differentiate S. boulardii from Saccharomyces cerevisiae The majority of prior studies stated that S. boulardii exhibits sluggish or halted galactose utilization...
May 15, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29508268/effect-of-a-preparation-of-four-probiotics-on-symptoms-of-patients-with-irritable-bowel-syndrome-association-with-intestinal-bacterial-overgrowth
#10
Konstantinos Leventogiannis, Paraskevas Gkolfakis, Georgios Spithakis, Aikaterini Tsatali, Aikaterini Pistiki, Athanasios Sioulas, Evangelos J Giamarellos-Bourboulis, Konstantinos Triantafyllou
The effect of probiotics on small intestinal bacterial overgrowth (SIBO) in irritable bowel syndrome (IBS) has never been studied so far. In this prospective trial, five patients with IBS and SIBO and 21 patients with IBS without SIBO were administered an oral capsule containing Saccharomyces boulardii, Bifidobacterium lactis, Lactobacillus acidophilus, and Lactobacillus plantarum (Lactolevure® ) every 12 h for 30 days. SIBO was defined by quantitative culture of the third part of the duodenum; IBS was defined by the Rome III criteria...
March 5, 2018: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29498738/blastocystis-hominis-transmission-by-non-potable-water-a-case-report-in-italy
#11
Maria Cristina Angelici, Chiara Nardis, Riccardo Scarpelli, Paola Ade
In the reported case, a 41-year-old Italian man came to the clinician's observation reporting cramps, bloating and watery diarrhoea a few days after drinking water indicated as unpotable from a fountain in a farm area. The medical suspicion was directed at both gluten intolerance and enteric infection, eventually of waterborne origin. Gluten intolerance was investigated by intestinal biopsy and excluded, while stool analyses ruled out infective bacteriological or viral agents and parasites. Subsequently, a persistent eosinophilia was revealed and a parasitological analysis was again suggested, planning for a more sensitive molecular method...
March 2, 2018: New Microbiologica
https://www.readbyqxmd.com/read/29449779/-saccharomyces-boulardii-cncm-i-745-improves-intestinal-enzyme-function-a-trophic-effects-review
#12
REVIEW
Margret I Moré, Yvan Vandenplas
Several properties of the probiotic medicinal yeast Saccharomyces boulardii CNCM I-745 contribute to its efficacy to prevent or treat diarrhoea. Besides immunologic effects, pathogen-binding and anti-toxin effects, as well as positive effects on the microbiota, S boulardii CNCM I-745 also has pronounced effects on digestive enzymes of the brush border membrane, known as trophic effects. The latter are the focus of this review. Literature has been reviewed after searching Medline and PMC databases. All relevant non-clinical and clinical studies are summarized...
2018: Clinical Medicine Insights. Gastroenterology
https://www.readbyqxmd.com/read/29447227/probiotic-effect-of-pichia-pastoris-x-33-produced-in-parboiled-rice-effluent-and-ypd-medium-on-broiler-chickens
#13
Diego Gil de Los Santos, João Rodrigo Gil de Los Santos, Carlos Gil-Turnes, Giana Gaboardi, Luiza Fernandes Silva, Rodrigo França, Cristina Gevehr Fernandes, Fabricio Rochedo Conceição
In a previous paper we showed that the yeast Pichia pastoris X-33 grown in parboiled rice effluent supplemented with glycerol byproduct from the biodiesel industry improved the quality of the effluent. In this paper we show the validation of this yeast (PPE) as probiotic for broilers. Its effect on feed efficiency and immunomodulation was compared with the same yeast grown in yeast peptone dextrose medium (PPY), with Saccharomyces boulardii (SBY) and with the controls fed unsupplemented feed (CON). One-day-old female chicks were vaccinated against infectious bursal disease (IBD) and the titers of anti-IBD antibodies were measured by ELISA...
2018: PloS One
https://www.readbyqxmd.com/read/29429459/-clinical-effect-of-saccharomyces-boulardii-powder-combined-with-azithromycin-sequential-therapy-in-treatment-of-children-with-diarrhea-secondary-to-mycoplasma-pneumoniae-pneumonia
#14
Qi-Fen Chen, Yi-Wei Zhang
OBJECTIVE: To investigate the clinical effect of Saccharomyces boulardii powder combined with azithromycin sequential therapy in the treatment of children with diarrhea secondary to Mycoplasma pneumoniae pneumonia. METHODS: A total of 88 children with diarrhea secondary to Mycoplasma pneumoniae pneumonia between June 2015 and March 2017 were divided into control group and study group using a random number table, with 44 children in each group. The children in the control group were given routine treatment combined with azithromycin sequential therapy, and those in the study group were given oral Saccharomyces boulardii powder in addition to the treatment in the control group until the end of azithromycin sequential therapy...
February 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29383669/probiotics-for-prevention-and-treatment-of-clostridium-difficile-infection
#15
Lorena Valdés-Varela, Miguel Gueimonde, Patricia Ruas-Madiedo
Probiotics have been claimed as a valuable tool to restore the balance in the intestinal microbiota following a dysbiosis caused by, among other factors, antibiotic therapy. This perturbed environment could favor the overgrowth of Clostridium difficile and, in fact, the occurrence of C. difficile-associated infections (CDI) is being increasing in recent years. In spite of the high number of probiotics able to in vitro inhibit the growth and/or toxicity of this pathogen, its application for treatment or prevention of CDI is still scarce since there are not enough well-defined clinical studies supporting efficacy...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29358890/probiotic-monotherapy-and-helicobacter-pylori-eradication-a-systematic-review-with-pooled-data-analysis
#16
Giuseppe Losurdo, Rossella Cubisino, Michele Barone, Mariabeatrice Principi, Gioacchino Leandro, Enzo Ierardi, Alfredo Di Leo
AIM: To define probiotic monotherapy effect on Helicobacter pylori ( H. pylori ) status by performing a systematic review. METHODS: Methods of analysis and inclusion criteria were based on PRISMA recommendations. Relevant publications were identified by searching PubMed, MEDLINE, Science Direct, and EMBASE. The end-point was to estimate eradication rate and urea breath test delta value before and after probiotic monotherapy across all studies and, overall, with a pooled data analysis...
January 7, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29340656/antagonistic-effect-of-saccharomyces-cerevisiae-ktp-and-issatchenkia-occidentalis-apc-on-hyphal-development-and-adhesion-of-candida-albicans
#17
K Lohith, K A Anu-Appaiah
The morphological transition from yeast to a hyphal form, as well as the adhesion capability to the gastrointestinal tract, are implicated virulent determinant in Candida albicans and could be potential targets for prevention of the opportunistic pathogen. Based on this rationale, two yeast strains Saccharomyces cerevisiae KTP and Issatchenkia occidentalis ApC along with reference strain Saccharomyces boulardii NCDC 363 were screened for the probiotic potential. Characters like pH, temperature, bile, simulated gastrointestinal juice tolerance tests, and Caco-2 cell line adhesion assay were determined in the present study...
January 11, 2018: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/29331687/probiotics-bacillus-toyonensis-and-saccharomyces-boulardii-improve-the-vaccine-immune-response-to-bovine-herpesvirus-type-5-in-sheep
#18
Talita Bandeira Roos, Carina Martins de Moraes, Régis Tuchtenhagen Sturbelle, Luana Alves Dummer, Geferson Fischer, Fábio Pereira Leivas Leite
There have been significant efforts toward the development of more efficient vaccines for animal health. A strategy that may be used to improve vaccine efficacy is the use of probiotics. Bovine herpesvirus 5 (BoHV-5) is an example of an important animal pathogen for which vaccines have provided only limited protection. In this study, we examined the use of the probiotics Bacillus toyonensis and Saccharomyces boulardii as a potential immune modulator to improve vaccine efficiency. Thirty, 5-month-old lambs were randomly grouped in three lots of 10 each and vaccinated at days 0, 21 and 42 of the experiment...
April 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29259371/probiotics-for-gastrointestinal-disorders-proposed-recommendations-for-children-of-the-asia-pacific-region
#19
REVIEW
Donald Cameron, Quak Seng Hock, Musal Kadim, Neelam Mohan, Eell Ryoo, Bhupinder Sandhu, Yuichiro Yamashiro, Chen Jie, Hans Hoekstra, Alfredo Guarino
Recommendations for probiotics are available in several regions. This paper proposes recommendations for probiotics in pediatric gastrointestinal diseases in the Asia-Pacific region. Epidemiology and clinical patterns of intestinal diseases in Asia-Pacific countries were discussed. Evidence-based recommendations and randomized controlled trials in the region were revised. Cultural aspects, health management issues and economic factors were also considered. Final recommendations were approved by applying the Likert scale and rated using the GRADE system...
December 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29212912/effect-of-saccharomyces-boulardii-in-dog-with-chronic-enteropathies-double-blinded-placebo-controlled-study
#20
Simona D'Angelo, Federico Fracassi, Francesca Bresciani, Roberta Galuppi, Alessia Diana, Nikolina Linta, Giuliano Bettini, Maria Morini, Marco Pietra
Saccharomyces boulardii is used to treat acute and chronic enteropathies in humans, but to date, no studies have evaluated the use of this yeast in dogs. The current study, a prospective non-randomised, double-blinded, placebo-controlled study, evaluated the effects of S boulardii in healthy dogs and dogs with chronic enteropathies (CE). Four healthy dogs and 20 dogs with CE were included. In healthy dogs, S boulardii was administered for 10 days. Possible short-term adverse effects were recorded, and quantitative stool cultures for yeasts were performed...
March 3, 2018: Veterinary Record
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