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Oral cavity tumors

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https://www.readbyqxmd.com/read/28531869/a-rare-case-of-subacute-appendicitis-actinomycosis-as-the-final-pathology-reports-a-case-report-and-literature-review
#1
G A Gómez-Torres, O S Ortega-Gárcia, E G Gutierrez-López, C A Carballido-Murguía, J A Flores-Rios, C R López-Lizarraga, C A Bautista López, C F Ploneda-Valencia
INTRODUCTION: Acute appendicitis is the most common indication for an emergency abdominal surgery in the world, with a lifetime incidence of around 10%. Actinomycetes are the etiology of appendicitis in only 0.02%-0.06%, having as the final pathology report a chronic inflammatory response; less than 10% of the cases are diagnosed before surgery. Here, we present the case of a subacute appendicitis secondary to actinomycosis. CASE REPORT: A 39-year-old male presented with a twelve-day evolution of intermittent abdominal pain in the right lower quadrant, treated at the beginning with ciprofloxacin and urinary analgesic...
May 15, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28529274/pleomorphic-adenoma-of-the-labial-gland-characterized-by-reticular-pattern-of-myoepithelial-cells-in-a-dog
#2
Mizuki Kuramochi, Takeshi Izawa, Shin Nishimura, Terumasa Shimada, Mitsuru Kuwamura, Jyoji Yamate
An 11-year-old female golden retriever dog had a mass at the right corner of the upper lip, which gradually increased in size and protruded into the oral cavity. The mass was removed surgically. The cut surface of the mass was smooth, whitish and solid, and covered by the oral mucosal membrane. Histopathologically, the mass consisted mainly of reticular pattern of short spindle cells that stained positively for cytokeratin AE1/AE3, α-smooth muscle actin and p63, suggestive of a myoepithelial cell phenotype...
May 20, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28522781/laparoscopic-gastric-resections-with-per-oral-specimen-extraction-in-treatment-of-intramural-gastric-tumors
#3
Maciej Stanek, Piotr Major, Mateusz Wierdak, Michał Pędziwiatr, Dorota Radkowiak, Anna Zychowicz, Andrzej Budzyński
AIM: The goal of this work was to present our experiences and results of treatment of gastric tumors using the per oral specimen extraction (POSE) technique. MATERIAL AND METHODS: A retrospective analysis a group of patients treated with laparoscopic stomach wedge resection of gastrointestinal stromal tumor (GIST). During that time 50 patients underwent laparoscopy due to the suspicion of GIST. In 12 patients resected material was removed endoscopically per os (POSE)...
February 28, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28522603/smad4-loss-is-associated-with-cetuximab-resistance-and-induction-of-mapk-jnk-activation-in-head-and-neck-cancer-cells
#4
Hiroyuki Ozawa, Ruchira Ranaweera, Evgeny Izumchenko, Eugene Makarev, Alex Zhavoronkov, Elana J Fertig, Jason D Howard, Ana Markovic, Atul Bedi, Rajani Ravi, Jimena Perez, Quynh-Thu Le, Christina S Kong, Richard C K Jordan, Hao Wang, Hyunseok Kang, Harry Quon, David Sidransky, Christine H Chung
Purpose: We previously demonstrated an association between decreased SMAD4 expression and cetuximab resistance in head and neck squamous cell carcinoma (HNSCC). The purpose of this study was to further elucidate the clinical relevance of SMAD4 loss in HNSCC. Experimental Design: SMAD4 expression was assessed by immunohistochemistry in 130 newly diagnosed and 43 recurrent HNSCC patients. Correlative statistical analysis with clinicopathological data was also performed. OncoFinder, a bioinformatics tool, was used to analyze molecular signaling in TCGA tumors with low or high SMAD4 mRNA levels...
May 18, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28522188/an-update-on-myofibromas-and-myofibromatosis-affecting-the-oral-regions-with-report-of-24-new-cases
#5
Molly Housley Smith, John D Reith, Donald M Cohen, Nadim M Islam, Kimberly T Sibille, Indraneel Bhattacharyya
OBJECTIVES: Myofibromas are uncommon soft tissue tumors exhibiting considerable histopathologic overlap with other benign and malignant entities. The treatment of lesions arising in the oral cavity is controversial. Here, we present 24 new cases and review the literature. STUDY DESIGN: A search for oral myofibromas was performed within the archives of the University of Florida Oral Pathology and Surgical Pathology Services (1994-2015). Demographic information and immunohistochemical results were recorded...
April 5, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28517962/inhibition-of-the-continuum-of-radiation-induced-normal-tissue-injury-by-a-redox-active-mn-porphyrin
#6
Samuel R Birer, Chen-Ting Lee, Kingshuk Roy Choudhury, Kenneth H Young, Ivan Spasojevic, Ines Batinic-Haberle, James D Crapo, Mark W Dewhirst, Kathleen A Ashcraft
Normal tissue damage after head and neck radiotherapy involves a continuum of pathologic events to the mucosa, tongue and salivary glands. We examined the radioprotective effects of MnBuOE, a redox-active manganese porphyrin, at three stages of normal tissue damage: immediate (leukocyte endothelial cell [L/E] interactions), early (mucositis) and late (xerostomia and fibrosis) after treatment. In this study, mice received 0 or 9 Gy irradiation to the oral cavity and salivary glands ± MnBuOE treatment. Changes in leukocyte-endothelial cell interactions were measured 24 h postirradiation...
May 18, 2017: Radiation Research
https://www.readbyqxmd.com/read/28509953/hyalinizing-clear-cell-carcinoma-of-the-tonsil-a-case-report
#7
Bridget Burgess, Vijayalakshmi Ananthanarayanan, Steven Charous
Hyalinzing clear cell carcinoma is a rare tumor of the oral cavity and is even more rarely located in the tonsil. Here, we present a case report of a pedunculated tonsillar mass in a nearly asymptomatic patient that was present for 2 years prior to removal. Complete surgical excision was achieved and no adjuvant therapy was recommended. We include a discussion of this rare pathology and its typical clinical presentation and course.
May 16, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28504188/discrepancy-between-clinical-and-pathological-neck-staging-in-oral-cavity-carcinomas
#8
Vânia Henriques, Eduardo Breda, Eurico Monteiro
INTRODUCTION: The presence of cervical lymph node metastases in patients with oral cavity squamous cell carcinoma reduces survival by up to 50%. OBJECTIVE: The aims of this study are to assess the accuracy of clinical N staging versus pathological N staging and its impact on survival in order to identify predictive factors associated with the presence of occult neck metastases. METHODS: Outcomes of 105 patients with oral cavity squamous cell carcinoma who underwent surgical treatment of the primary tumor and neck were retrospectively evaluated...
May 11, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28503348/emerging-trends-in-the-epidemiological-pattern-of-head-and-neck-cancers-in-lagos-nigeria
#9
O A Erinoso, E Okoturo, O M Gbotolorun, O A Effiom, N A Awolola, S S Soyemi, R T Oluwakuyide
BACKGROUND: Unfortunately, despite an increase in medical knowledge, survival rates of head and neck cancers (HNCs) have not been observed to improve greatly. This is true, especially in tumors located in obscure primary sites or late presentation. AIM: The purpose of this study is to assess the epidemiologic pattern of HNCs and to evaluate its emerging trends and patterns in Lagos state. SUBJECTS AND METHODS: A retrospective study was conducted from 2003 to 2013 that analyzed histologically diagnosed cases of HNC at the Pathology Departments of the two tertiary teaching hospitals in Lagos...
September 2016: Annals of Medical and Health Sciences Research
https://www.readbyqxmd.com/read/28496456/swallowing-disorders-after-oral-cavity-and-pharyngolaryngeal-surgery-and-role-of-imaging
#10
REVIEW
Caterina Giannitto, Lorenzo Preda, Valeria Zurlo, Luigi Funicelli, Mohssen Ansarin, Salvatore Di Pietro, Massimo Bellomi
Head and neck squamous cell carcinoma is the sixth most common cancer diagnosed worldwide and the eighth most common cause of cancer death. Malignant tumors of the oral cavity, oropharynx, and larynx can be treated by surgical resection or radiotheraphy with or without chemotheraphy and have a profound impact on quality of life functions, including swallowing. When surgery is the chosen treatment modality, the patient may experience swallowing impairment in the oral and pharyngeal phases of deglutition. A videofluoroscopic study of swallow enables the morphodynamics of the pharyngeal-esophageal tract to be accurately examined in patients with prior surgery...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28489662/metastasis-of-a-renal-collecting-duct-adenocarcinoma-to-the-oral-cavity-after-tooth-extraction
#11
Suna Erkilic, Aydin Keskinruzgar, Zehra Bozdag, Omer Gunhan
Metastatic tumors rarely occur in the oral cavity. The most common of the oral metastases are lung cancers in males, and breast and genital cancers in females. The most common primary tumor metastasis to the oral cavity is from the lung, kidney, liver, prostate, and colorectal cancers. The metastatic lesions are similar to oral lesions such as pyogenic granuloma, giant cell lesions, gingival polyps, hemangioma, peripheral fibroma, and adenoid squamous cell carcinoma. Therefore, the diagnosis of primary tumors is challenging...
May 9, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28486147/multimodal-assessment-of-sers-nanoparticle-biodistribution-post-ingestion-reveals-new-potential-for-clinical-translation-of-raman-imaging
#12
Jos L Campbell, Elliott D SoRelle, Ohad Ilovich, Orly Liba, Michelle L James, Zhen Qiu, Valerie Perez, Carmel T Chan, Adam de la Zerda, Cristina Zavaleta
Despite extensive research and development, new nano-based diagnostic contrast agents have faced major barriers in gaining regulatory approval due to their potential systemic toxicity and prolonged retention in vital organs. Here we use five independent biodistribution techniques to demonstrate that oral ingestion of one such agent, gold-silica Raman nanoparticles, results in complete clearance with no systemic toxicity in living mice. The oral delivery mimics topical administration to the oral cavity and gastrointestinal (GI) tract as an alternative to intravenous injection...
April 28, 2017: Biomaterials
https://www.readbyqxmd.com/read/28485283/effect-of-copper-ii-the-activity-of-glutathione-peroxidase-in-patients-with-head-and-neck-cancer
#13
Katarzyna Malinowska, Alina Morawiec-Sztandera, Ireneusz Majsterek, Dariusz Kaczmarczyk
INTRODUCTION: Head and neck squamous cell carcinoma (HNSCC) accounts for about 6% of all malignant cancers. In the epidemiology of oral cavity neoplasm, important risk factors include: tobacco smoking, alcohol abuse, bad oral hygiene, papilloma virus infection, riboflavin and iron deficiency. OBJECTIVE: The objective of the investigation was a synthesis of Cu(II) complex and the evaluation of antioxidative enzymatic barrier in red blood cells of patients with head and neck tumor as well as in the control group...
November 20, 2016: Otolaryngologia Polska
https://www.readbyqxmd.com/read/28484539/sinonasal-teratocarcinosarcoma-involving-nasal-cavity-nasopharynx-and-all-paranasal-sinuses-with-bilateral-orbital-and-intracranial-extension-a-rare-case-report
#14
Dhruba Jyoti Kurmi, Radhey Shyam Mittal, Achal Sharma, Ashok Gandhi, Shashi Singhvi
Sinonasal teratocarcinosarcoma (SNTCS) is one of the rarest, aggressive malignant neoplasms of sinonasal tract, consisting of primitive neuroepithelial elements with various malignant epithelial and mesenchymal components. Previously described as teratoid carcinosarcoma, malignant teratoma, or blastoma, SNTCS constitutes less than 1% of all cancers and approximately 3% of all malignancies of head and neck region, which is mainly located in the nasal cavity and paranasal sinuses, although tumors occurring in other locations including the nasopharynx and oral cavity have been described...
April 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28479936/presage-of-oncolytic-virotherapy-for-oral-cancer-with-herpes-simplex-virus
#15
REVIEW
Yoshiaki Yura
A virus is a pathogenic organism that causes a number of infectious diseases in humans. The oral cavity is the site at which viruses enter and are excreted from the human body. Herpes simplex virus type 1 (HSV-1) produces the primary infectious disease, gingivostomatitis, and recurrent disease, labial herpes. HSV-1 is one of the most extensively investigated viruses used for cancer therapy. In principle, HSV-1 infects epithelial cells and neuronal cells and exhibits cytotoxicity due to its cytopathic effects on these cells...
May 2017: Japanese Dental Science Review
https://www.readbyqxmd.com/read/28479700/massive-noninfiltrating-angiolipoma-of-the-buccal-mucosa-report-of-an-extremely-rare-case
#16
Srikanth Dhanala, Nagaraju Tanneru
We present an extremely rare case of noninfiltrating angiolipoma (AL) of the buccal mucosa in a 90-year-old patient reaching a size of 14 cm × 10 cm. AL is rare in the soft tissues of oral cavity, and till date, only 22 cases have been reported, including our case. If size be taken into consideration, our case can be considered to be the first in literature to reach this massive size. Surgical excision of the tumor mass was performed. The histopathological findings confirmed the diagnosis of noninfiltrating AL...
January 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28479698/leukoplakia-of-buccal-mucosa-with-transformation-into-spindle-cell-carcinoma-a-rare-case-report
#17
Shikha Gupta, Sunita Gupta, Aadithya B Urs, Khushboo Singh
Spindle cell carcinoma (SpCC), a variant of squamous cell carcinoma, is a biphasic malignant neoplasm that occurs mainly in the upper aerodigestive tract. It is uncommon in oral cavity, accounting for <1% of all tumors in oral cavity. Furthermore, it is uncommon for oral potentially malignant disorders such as leukoplakia to undergo transformation into SpCC. In this paper, we are reporting a case of SpCC of buccal mucosa in a 35-year-old female who was previously diagnosed with oral leukoplakia past 6 months...
January 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28468196/extra-oral-excision-of-a-buccal-fat-pad-lipoma
#18
Guilherme Dos Santos Trento, Diego José Stringhini, Nelson Luis Barbosa Rebellato, Rafaela Scariot
Lipomas and its variants are common soft tissue tumors, and however occur infrequently in the oral and maxillofacial region. Their incidence in the oral cavity is low among all oral lesions. Oral lipoma is yellowish and soft to palpation, and histologically can be mistaken by other lipoma variants. The aim of this study is to report a case of a lipoma located at the buccal fat pad which was removed through an extra-oral access. A 43-year-old male is presenting an augmentation in the right buccal region, being a soft consistency mobile lesion with 1...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28468159/association-between-odontoma-and-impacted-teeth
#19
Gaetano Isola, Marco Cicciù, Luca Fiorillo, Giovanni Matarese
Odontoma is considered to be the most common odontogenic tumor of the oral cavity. Most odontomas are asymptomatic and are discovered during routine radiographic investigations and can cause disturbances in the eruption of the teeth, most commonly delayed eruption or deflection. By a retrospective study design, demographic and clinical data regarding patients who presented odontomas from year 1995 to 2015 were obtained in order and the influence of active therapy on the dentition and on the treatment of impacted teeth was analyzed...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28466780/tim-3-expressing-macrophages-are-functionally-suppressed-and-expanded-in-oral-squamous-cell-carcinoma-due-to-virus-induced-gal-9-expression
#20
Jianfeng Dong, Lijun Cheng, Minchao Zhao, Xiangfeng Pan, Zhiqiang Feng, Dawei Wang
Oropharyngeal head and neck squamous cell carcinoma is a common malignant tumor in the oral cavity. High-risk human papillomavirus 16 infection is a major cause of oropharyngeal head and neck squamous cell carcinoma development. Strong antitumor immune responses, especially CD8(+) T cell responses, are thought to be essential to effective cancer treatment and are associated with better prognosis in oropharyngeal head and neck squamous cell carcinoma. In this study, we examined the role of the Tim-3/Gal-9 pathway in oropharyngeal head and neck squamous cell carcinoma patients...
May 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
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