Alekhya Lavu, Christine Vaccaro, Enav Zusman, Laila Aboulatta, Basma Aloud, Silvia Alessi-Severini, Lara Haidar, Payam Peymani, Marcus C Ng, Chelsea Ruth, Jamison Falk, Brianne Desrochers, Eunice Valencia, Walid Shouman, Rasheda Rabbani, Sherif Eltonsy
AIM: We aimed to systematically synthesize the current published literature on neonatal growth outcomes associated with antiseizure medications (ASMs) use during pregnancy. METHODS: We searched seven databases, from inception to March 23rd, 2022. We investigated small for gestational age (SGA) and low birth weight (LBW) as primary outcomes and birth weight, birth height, cephalization index and head circumference as secondary outcomes. The primary analysis included pregnant people exposed to any ASM compared with unexposed pregnant people...
April 18, 2023: British Journal of Clinical Pharmacology