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https://www.readbyqxmd.com/read/28728374/analysis-of-metabolomic-patterns-in-thoroughbreds-before-and-after-exercise
#1
Hyun-Jun Jang, Duk-Moon Kim, Kyu-Bong Kim, Jeong-Woong Park, Jae-Young Choi, Jin Hyeog Oh, Ki-Duk Song, Suhkmann Kim, Byung-Wook Cho
Objective: Evaluation of exercise effects in racehorse is important in horseracing industry and animal health care. In this study, we compared metabolic patterns between before and after exercise to screen metabolic biomarkers for exercise effects in thoroughbreds. Methods: The concentration of metabolites in muscle, plasma, and urine was measured by 1H NMR spectroscopy analysis and the relative metabolite levels in the three samples were compared between before and after exercise...
June 27, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28728286/-corneal-astigmatism-among-2-085-age-related-cataract-patients-before-surgery
#2
Y Wang, M Ke, T Zheng, J Zhang, W H Wang, S Y Wu
Objective: To investigate the characteristics and distribution of corneal astigmatism before surgery among age-related cataract patients in the Hubei area. Methods: Retrospective study. From January 1, 2012 to July 31, 2016, IOL Master measurements of all qualified cataract surgery candidates were retrospectively collected. Descriptive statistical analysis was used to assess the degree, distribution and type of corneal astigmatism. Kolmogorov-Smirnov (K-S) test was used to evaluate the normal distribution of variables...
July 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28728282/-epidemiologic-study-of-tear-film-lipid-layer-thickness-measurement-in-the-population-of-taishitun-community-in-beijing
#3
Q F Liang, X H Du, Y D Su, N L Wang, Z J Wei, Antoine Labbé
Objective: To investigate the distribution of tear film lipid layer thickness (LLT) and the relationship between symptoms and signs of dry eye and tear film LLT in the population of Taishitun Community in Beijing. Methods: A cross-sectional study. From May 2016 to August 2016, three streets of Taishitun Community were randomly selected as survey districts and 540 persons were taken as investigation subjects. Every participant completed 6 items of dry eye examinations as follows: questionnaire (Ocular Surface Disease Index, OSDI), measurement of tear film LLT, tear film break-up time (TBUT), corneal and conjunctival staining, SchirmerⅠtest and the infrared meibomian photography...
July 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28728240/-the-implantation-of-bonebridge-in-bilateral-congenital-malformation-of-external-and-middle-ear
#4
S Q Zhao, R Ren, D M Han, Y Li, X B Ma, D N Wang, Y L Li
Objective: To evaluate the auditory efficacy of Bonebridge implantation in patients with bilateral congenital malformation of external and middle ear. Methods: Eleven cases (6 males and 5 females) had unilateral Bonebridge implantation. The age ranged from 8 to 26 and the average age was 16.9. Seven to ten days after operation, the first fitting was undergone. In acoustic sound field, the average auditory thresholds were respectively measured for unaided ears and Bonebridge implanted ears by pure tone auditory (PTA, 0...
July 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28728169/correlations-between-macular-skin-and-serum-carotenoids
#5
Christopher D Conrady, James P Bell, Brian M Besch, Aruna Gorusupudi, Kelliann Farnsworth, Igor Ermakov, Mohsen Sharifzadeh, Maia Ermakova, Werner Gellermann, Paul S Bernstein
Purpose: Ocular and systemic measurement and imaging of the macular carotenoids lutein and zeaxanthin have been employed extensively as potential biomarkers of AMD risk. In this study, we systematically compare dual wavelength retinal autofluorescence imaging (AFI) of macular pigment with skin resonance Raman spectroscopy (RRS) and serum carotenoid levels in a clinic-based population. Methods: Eighty-eight patients were recruited from retina and general ophthalmology practices from a tertiary referral center and excluded only if they did not have all three modalities tested, had a diagnosis of macular telangiectasia (MacTel) or Stargardt disease, or had poor AFI image quality...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28728098/longitudinal-study-of-religiosity-and-mental-health-of-adolescents-with-psychiatric-problems-the-trails-study
#6
W van der Jagt-Jelsma, M de Vries-Schot, P Scheepers, P A M van Deurzen, H Klip, J K Buitelaar
PURPOSE: This study used longitudinal data to examine the influence of the religiosity of pre-adolescents with psychiatric problems on the course of mental health during adolescence. METHODS: In the TRAILS clinical cohort of 543 pre-adolescents (10-12 years), mental health problems were assessed using self-report at baseline, T2 (12-14 years), T3 (14-17 years), and T4 (17-21 years). The Youth Self Report (YSR) was used at baseline, T2, and T3, and the Adult Self Report (ASR) was used at T4...
June 15, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728092/checking-the-predictive-accuracy-of-basic-symptoms-against-ultra-high-risk-criteria-and-testing-of-a-multivariable-prediction-model-evidence-from-a-prospective-three-year-observational-study-of-persons-at-clinical-high-risk-for-psychosis
#7
M P Hengartner, K Heekeren, D Dvorsky, S Walitza, W Rössler, A Theodoridou
BACKGROUND: The aim of this study was to critically examine the prognostic validity of various clinical high-risk (CHR) criteria alone and in combination with additional clinical characteristics. METHODS: A total of 188 CHR positive persons from the region of Zurich, Switzerland (mean age 20.5 years; 60.2% male), meeting ultra high-risk (UHR) and/or basic symptoms (BS) criteria, were followed over three years. The test battery included the Structured Interview for Prodromal Syndromes (SIPS), verbal IQ and many other screening tools...
June 3, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28728077/comparison-of-spinal-stability-following-motor-control-and-general-exercises-in-nonspecific-chronic-low-back-pain-patients
#8
MohammadBagher Shamsi, Javad Sarrafzadeh, Aliashraf Jamshidi, Navid Arjmand, Farshid Ghezelbash
BACKGROUND: Motor control exercise was claimed to improve spinal stability in patients with chronic non-specific back pain, but to investigate the effectiveness of this exercise, other outcome measures have been used rather than spinal stability itself. The aim of our study is to assess motor control exercise effects on spinal stability using a biomechanical model. METHODS: Fifty-one patients were assigned to either motor control or general exercises. Before and after trainings, participants were tested for spinal stability at seven isometric tasks...
July 8, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28728076/age-explains-limited-hip-extension-recovery-at-one-year-from-total-hip-arthroplasty
#9
Davide Mazzoli, Erika Giannotti, Maria Longhi, Paolo Prati, Stefano Masiero, Andrea Merlo
BACKGROUND: To investigate the dependency of the one-year recovery in gait after total hip arthroplasty on age and preoperative conditions. METHODS: Longitudinal retrospective study on 20 elderly patients with unilateral total hip arthroplasty consequent to hip osteoarthritis, assessed by gait analysis before surgery (T0), 2weeks (T1), 6 (T2) and 12months (T3) post-surgery. A set of variables assessing primary gait deviations and compensatory mechanisms were extracted from gait analysis data...
July 5, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28728066/baseline-serum-phosphatidylcholine-plasmalogen-concentrations-are-inversely-associated-with-incident-myocardial-infarction-in-patients-with-mixed-peripheral-artery-disease-presentations
#10
Joseph V Moxon, Rhondda E Jones, Gerard Wong, Jacquelyn M Weir, Natalie A Mellett, Bronwyn A Kingwell, Peter J Meikle, Jonathan Golledge
BACKGROUND AND AIMS: Despite current best care, patients with peripheral artery disease (PAD) remain at high risk of myocardial infarction, and biomarkers to more accurately assess cardiovascular risk are needed. This study assessed the relationship between the serum lipidome and incident myocardial infarction in a cohort of PAD patients. METHODS: 265 PAD patients were followed up for a median of 23 months, during which 18 people suffered a myocardial infarction...
June 29, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28728008/pen-on-paper-strategy-for-point-of-care-testing-rapid-prototyping-of-fully-written-microfluidic-biosensor
#11
Zedong Li, Fei Li, Yue Xing, Zhi Liu, Minli You, Yingchun Li, Ting Wen, Zhiguo Qu, Xiao Ling Li, Feng Xu
Paper-based microfluidic biosensors have recently attracted increasing attentions in point-of-care testing (POCT) territories benefiting from their affordable, accessible and eco-friendly features, where technologies for fabricating such biosensors are preferred to be equipment free, easy-to-operate and capable of rapid prototyping. In this work, we developed a pen-on-paper (PoP) strategy based on two custom-made pens, i.e., a wax pen and a conductive-ink pen, to fully write paper-based microfluidic biosensors through directly writing both microfluidic channels and electrodes...
July 1, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28728007/direct-immune-detection-of-cortisol-by-chemiresistor-graphene-oxide-sensor
#12
Yo-Han Kim, Kyungmin Lee, Hunsang Jung, Hee Kyung Kang, Jihoon Jo, In-Kyu Park, Hyun Ho Lee
In this study, a biosensor to detect a stress biomarker of cortisol using cortisol monoclonal antibody (c-Mab) covalently immobilized on reduced graphene oxide (rGO) channel as electrical sensing element was demonstrated. Highly specific immune-recognition between the c-Mab and the cortisol was identified and characterized on a basis of resistance change at the rGO channel based chemiresistor sensor achieving the limit of detection of 10pg/mL (27.6 pM). In addition, cortisol concentrations of real human salivary sample and buffer solution of rat adrenal gland acute slices, which could secret the cortisol induced by adrenocorticotropic hormone (ACTH), were directly measured by the chemiresistor corresponding to the specific sensing of the cortisol...
July 11, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28727935/food-addiction-a-barrier-for-effective-weight-management-for-obese-adolescents
#13
Connie L Tompkins, Jennifer Laurent, David W Brock
BACKGROUND: Findings from studies of food addiction in adults suggest those with food addiction are less successful in weight-loss interventions. Little is known about food addiction in obesity treatment-seeking adolescents; therefore, the purpose of this study was to explore the prevalence of food addiction and correlates of food addiction symptoms in obese adolescents entering an outpatient, weight management program. METHODS: Obese adolescents (n = 26) were administered the Yale Food Addiction Scale for Children (YFAS-C), measures of appetitive responsiveness, and health-related quality of life (HRQOL) before and following a 12-week, outpatient, behavioral weight management program...
July 20, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/28727923/height-prediction-from-ulna-length-of-critically-ill-patients
#14
Micheli S Tarnowski, Estela I Rabito, Daieni Fernandes, Mariane Rosa, Manoela L Oliveira, Vânia N Hirakata, Aline Marcadenti
BACKGROUND: Ulna length (UL) has been used in mathematical formulas to predict the body height of healthy and sick individuals. However, the evaluation of its use with patients admitted to intensive care units (ICU) is scarce. The objective of this study was to develop a mathematical equation to estimate critically ill patients' height using the UL measure and to evaluate its agreement with measured standing height. METHODS: This cross-sectional study was performed at the ICU of a tertiary hospital in Brazil...
July 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28727897/the-course-of-fear-of-cancer-recurrence-different-patterns-by-age-in-breast-cancer-survivors
#15
Daniëlle E J Starreveld, Sabine E Markovitz, Gerard van Breukelen, Madelon L Peters
OBJECTIVE: To examine the time course and predictors of fear of cancer recurrence (FCR) in breast cancer survivors over a period of 18 months after initial surgery. METHODS: Breast cancer patients (n = 267) were followed until 18 months after primary breast surgery. Shortly after surgery, participants completed the Life Orientation Test-Revised (LOT-R) to measure optimism and the Concerns about Recurrence Scale (CARS) to measure FCR. Mixed regression analysis was performed with age, optimism, marital status, education, type of surgery, with or without lymphectomy, chemotherapy, hormonal therapy, or radiotherapy, time since surgery and all interactions with time as predictors of FCR...
July 20, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28727888/association-of-mental-health-status-with-perception-of-nasal-function
#16
Erika Strazdins, Yu Feng Nie, Raziqah Ramli, Tom Palesy, Jenna M Christensen, George Nicholas Marcells, Richard John Harvey
Importance: Mental health issues are thought to be overrepresented among patients undergoing rhinoplasty and may be associated with patient presentation prior to surgery. Objective: To assess the association of poor mental health with perception of nasal function. Design, Setting, and Participants: A cross-sectional study of patients presenting for airway assessment was performed from December 1, 2011, to October 31, 2015, at 2 tertiary rhinoplasty centers in Sydney, Australia...
July 20, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28727858/association-of-velopharyngeal-insufficiency-with-quality-of-life-and-patient-reported-outcomes-after-speech-surgery
#17
Aditi Bhuskute, Jonathan R Skirko, Christina Roth, Ahmed Bayoumi, Blythe Durbin-Johnson, Travis T Tollefson
Importance: Patients with cleft palate and other causes of velopharyngeal insufficiency (VPI) suffer adverse effects on social interactions and communication. Measurement of these patient-reported outcomes is needed to help guide surgical and nonsurgical care. Objectives: To further validate the VPI Effects on Life Outcomes (VELO) instrument, measure the change in quality of life (QOL) after speech surgery, and test the association of change in speech with change in QOL...
July 20, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28727839/cardiac-autonomic-modulation-induced-by-doxorubicin-in-a-rodent-model-of-colorectal-cancer-and-the-influence-of-fullerenol-pretreatment
#18
Nejka Potočnik, Martina Perše, Anton Cerar, Rade Injac, Žarko Finderle
The very effective anticancer drug doxorubicin (DOX) is known to have cardiotoxic side effects, which could be accompanied by autonomic modulation. Autonomic disbalance might even be an initiating mechanism underlying DOX-induced cardiotoxicity and can be studied noninvasively by the analysis of heart rate variability (HRV). A number of strategies have been assessed to predict chemotherapy-induced cardiac dysfunction while HRV, a potential detecting tool, has not yet been tested. Thus, we aimed to determine the effect of DOX treatment on HRV in a rat model of colorectal cancer...
2017: PloS One
https://www.readbyqxmd.com/read/28727836/the-disc-damage-likelihood-scale-diagnostic-accuracy-and-correlations-with-cup-to-disc-ratio-structural-tests-and-standard-automated-perimetry
#19
Andrea C Kara-José, Luiz Alberto S Melo, Bruno L B Esporcatte, Angelica T N H Endo, Mauro Toledo Leite, Ivan Maynart Tavares
Our objective was to compare the diagnostic accuracies of and to determine the correlations between the disc damage likelihood scale (DDLS) and anatomical and functional tests used for glaucoma detection. A total of 54 healthy subjects (54 eyes) and 47 primary open-angle glaucoma patients (47 eyes) were included in this cross-sectional observational study. DDLS scores and cup-to-disc (C/D) ratios were evaluated. Subjects underwent standard automated perimetry (SAP), optic disc and retinal nerve fiber layer (RNFL) imaging with time and spectral-domain optical coherence tomography (TD and SD-OCT), Heidelberg Retina Tomograph (HRT II), and scanning laser polarimetry (GDx-VCC)...
2017: PloS One
https://www.readbyqxmd.com/read/28727817/immunogenicity-of-a-novel-clade-b-hiv-1-vaccine-combination-results-of-phase-1-randomized-placebo-controlled-trial-of-an-hiv-1-gm-csf-expressing-dna-prime-with-a-modified-vaccinia-ankara-vaccine-boost-in-healthy-hiv-1-uninfected-adults
#20
Susan P Buchbinder, Nicole A Grunenberg, Brittany J Sanchez, Kelly E Seaton, Guido Ferrari, M Anthony Moody, Nicole Frahm, David C Montefiori, Christine M Hay, Paul A Goepfert, Lindsey R Baden, Harriet L Robinson, Xuesong Yu, Peter B Gilbert, M Juliana McElrath, Yunda Huang, Georgia D Tomaras
BACKGROUND: A phase 1 trial of a clade B HIV vaccine in HIV-uninfected adults evaluated the safety and immunogenicity of a DNA prime co-expressing GM-CSF (Dg) followed by different numbers and intervals of modified vaccinia Ankara Boosts (M). Both vaccines produce virus-like particles presenting membrane-bound Env. METHODS: Four US sites randomized 48 participants to receiving 1/10th the DNA dose as DgDgMMM given at 0, 2, 4, 6 and 8 months, or full dose DgDgM_M or DgDgMM_M regimens, given at 0, 2, 4, and 8 months, and 0, 2, 4, 6, and 10 months, respectively...
2017: PloS One
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