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https://www.readbyqxmd.com/read/27909400/the-demise-of-the-synapse-as-the-locus-of-memory-a-looming-paradigm-shift
#1
Patrick C Trettenbrein
Synaptic plasticity is widely considered to be the neurobiological basis of learning and memory by neuroscientists and researchers in adjacent fields, though diverging opinions are increasingly being recognized. From the perspective of what we might call "classical cognitive science" it has always been understood that the mind/brain is to be considered a computational-representational system. Proponents of the information-processing approach to cognitive science have long been critical of connectionist or network approaches to (neuro-)cognitive architecture, pointing to the shortcomings of the associative psychology that underlies Hebbian learning as well as to the fact that synapses are practically unfit to implement symbols...
2016: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/27909256/optimizing-the-multisectoral-nutrition-policy-cycle-a-systems-perspective
#2
Sascha Lamstein, Amanda Pomeroy-Stevens, Patrick Webb, Eileen Kennedy
Based on the data collected in Uganda, Nepal, and Ethiopia, the papers included in this supplement fill a critical gap in evidence regarding multisectoral National Nutrition Action Plans. The studies offer new data and new thinking on how and why governance, effective financial decentralization, and improved accountability all matter for nutrition actions in low-income countries. This introductory paper offers an overview of the current state of evidence and thinking on the multisectoral nutrition policy cycle, including how governance and financing support that process...
December 2016: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/27906523/developmental-evolution
#3
REVIEW
Robert Lickliter
Biologists and psychologists are re-thinking the long-standing premise of genes as the primary cause of development, a view widely embraced in 20th-century biology. This shift in thinking is based in large part on: (1) the growing appreciation of the complex, distributed regulatory dynamics of gene expression; and (2) the growing appreciation of the probabilistic, contingent, and situated nature of development. We now appreciate that what actually unfolds during individual development represents only one of many possibilities...
December 1, 2016: Wiley Interdisciplinary Reviews. Cognitive Science
https://www.readbyqxmd.com/read/27894237/new-insight-in-improving-therapeutic-efficacy-of-antipsychotic-agents-an-overview-of-improved-in-vitro-and-in-vivo-performance-efficacy-upgradation-and-future-prospects
#4
Zahid Hussain, Hnin Ei Thu, Ahmad Nazrun Shuid
Psychotic disorders are severe mental disorders that rigorously affect patient personality, critical thinking, and perceptional ability. High prevalence, global dissemination and limitations of conventional pharmacological approaches compel a significant burden to the patient, medical professionals and the healthcare system. To date, numerous orally administered therapies are available for the management of depressive disorders, schizophrenia, anxiety, bipolar disorders and autism spectrum problems. However, poor water solubility, erratic oral absorption, extensive first-pass metabolism, low oral bioavailability and short half-lives are major factors which limit the pharmaceutical significance and therapeutic feasibility of these agents...
November 25, 2016: Current Drug Targets
https://www.readbyqxmd.com/read/27893929/a-review-of-cost-communication-in-oncology-patient-attitude-provider-acceptance-and-outcome-assessment
#5
REVIEW
Ya-Chen Tina Shih, Chun-Ru Chien
The American Society of Clinical Oncology released its first guidance statement on the cost of cancer care in August 2009, affirming that patient-physician cost communication is a critical component of high-quality care. This forward-thinking recommendation has grown increasingly important in oncology practice today as the high costs of cancer care impose tremendous financial burden to patients, their families, and the health care system. For the current review, a literature search was conducted using the PubMed and Web of Science databases to identify articles that covered 3 topics related to patient-physician cost communication: patient attitude, physician acceptance, and the associated outcomes; and 15 articles from 12 distinct studies were identified...
November 28, 2016: Cancer
https://www.readbyqxmd.com/read/27893903/to-blog-or-not-to-blog-what-do-nursing-faculty-think
#6
Krista Jones, Mary Kate Garrity, Kathryn J VanderZwan, Iris Epstein, Arlene Burla de la Rocha
BACKGROUND: Nurse educators find themselves tasked with developing content that both is aesthetically appealing and engages today's technological learners while empowering them to apply their knowledge in clinical and classroom settings. Students engaging with social networking systems reported increased satisfaction with collaborative peer-to-peer learning experiences, socialization, self-reflection, peer critique, problem-solving skills, collation of evidence-based resources, and instructor performance...
December 1, 2016: Journal of Nursing Education
https://www.readbyqxmd.com/read/27893823/shared-decision-making-at-the-limit-of-viability-a-blueprint-for-physician-action
#7
Thierry Daboval, Sarah Shidler, Daniel Thomas
OBJECTIVE: To document interactions during the antenatal consultation between parents and neonatologist that parents linked to their satisfaction with their participation in shared decision making for their infant at risk of being born at the limit of viability. METHODS: This multiple-case ethnomethodological qualitative research study, included mothers admitted for a threatened premature delivery between 200/7 and 266/7 weeks gestation, the father, and the staff neonatologist conducting the clinical antenatal consultation...
2016: PloS One
https://www.readbyqxmd.com/read/27893345/quo-vadis-the-future-of-psychoanalysis
#8
Mauricio Cortina
Although contemporary psychoanalysis is split into different schools and traditions, there is growing support for some of the main tenets of contemporary psychodynamic thinking from attachment theory, infant research, developmental psychopathology, new models of motivation, the neuroscience of emotions and emotional regulation, and the discovery of different implicit and explicit memory systems. These tenets, which psychodynamic clinicians of all stripes encounter in their daily work with clients, are the following: (1) that large footprints are left over from infancy and childhood which involved insensitive, intrusive, frightening, or shaming care; (2) the carryover of these relational experiences into adulthood are expressed as unconscious expectations and attributions we make of others (transference and countertransference; (3) defensive processes and emotional regulation and deregulatory patterns develop to cope with these unhealthy relations...
December 2016: Psychoanalytic Review
https://www.readbyqxmd.com/read/27891106/episodic-and-semantic-memory-contribute-to-familiar-and-novel-episodic-future-thinking
#9
Tong Wang, Tong Yue, Xi Ting Huang
Increasing evidence indicates that episodic future thinking (EFT) relies on both episodic and semantic memory; however, event familiarity may importantly affect the extent to which episodic and semantic memory contribute to EFT. To test this possibility, two behavioral experiments were conducted. In Experiment 1, we directly compared the proportion of episodic and semantic memory used in an EFT task. The results indicated that more episodic memory was used when imagining familiar future events compared with novel future events...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27888859/treatment-adherence-is-always-worse-than-we-think-an-unresolved-problem-in-inflammatory-bowel-disease
#10
Fernando Gomollón
New diagnostic and treatment tools are the "stars" of scientific meetings but other aspects may have an even greater impact on patients' lives. Several new studies presented at DDW (Digestive Disease Week) 2016 demonstrated that: a) treatment adherence continues to be suboptimal even in the most advanced health systems; b) lack of adherence correlates with low treatment effectiveness, with higher levels of intestinal damage and higher costs; and c) the factor most consistently associated with poor adherence is age (the younger the patient, the poorer the adherence)...
September 2016: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/27884523/the-anthroposphere-as-an-anticipatory-system-open-questions-on-steering-the-climate
#11
Rocco Scolozzi, Davide Geneletti
Climate change research and action counteracting it affect everyone and would involve cross-societal transformations reshaping the anthroposphere in its entirety. Scrutinizing climate-related science and policies, we recognize attempts to steer the evolution of climate according to expected (or modelled) futures. Such attempts would turn the anthroposphere into a large "anticipatory system", in which human society seeks to anticipate and, possibly, to govern climate dynamics. The chief aim of this discussion paper is to open a critical debate on the climate change paradigm (CCP) drawing on a strategic and systemic framework grounded in the concept of anticipatory system sensu Rosen (1991)...
November 22, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27883355/-patient-doctor-relationship-from-perspective-of-the-karpman-drama-triangle
#12
REVIEW
Anna Samborska-Sablik, Zbigniew Sablik
Patients' confidence in doctors has been decreased for last years despite successes of Polish medicine. It seems to be related to particular conditions of patient - doctor relationship and patient's negative emotions may frequently burden it from the beginning. They may allow an interpersonal game, the Drama Triangle, to appear in the relationship. 3 persons are typically involved in the game: a victim, a persecutor and a rescuer. All of them neither feel guilty about the situation nor their activities are aimed at solving the crucial problem...
November 25, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27882594/-cuts-in-action-a-high-density-eeg-study-investigating-the-neural-correlates-of-different-editing-techniques-in-film
#13
Katrin S Heimann, Sebo Uithol, Marta Calbi, Maria A Umiltà, Michele Guerra, Vittorio Gallese
In spite of their striking differences with real-life perception, films are perceived and understood without effort. Cognitive film theory attributes this to the system of continuity editing, a system of editing guidelines outlining the effect of different cuts and edits on spectators. A major principle in this framework is the 180° rule, a rule recommendation that, to avoid spectators' attention to the editing, two edited shots of the same event or action should not be filmed from angles differing in a way that expectations of spatial continuity are strongly violated...
November 24, 2016: Cognitive Science
https://www.readbyqxmd.com/read/27881212/building-machines-that-learn-and-think-like-people
#14
Brenden M Lake, Tomer D Ullman, Joshua B Tenenbaum, Samuel J Gershman
Recent progress in artificial intelligence (AI) has renewed interest in building systems that learn and think like people. Many advances have come from using deep neural networks trained end-to-end in tasks such as object recognition, video games, and board games, achieving performance that equals or even beats humans in some respects. Despite their biological inspiration and performance achievements, these systems differ from human intelligence in crucial ways. We review progress in cognitive science suggesting that truly human-like learning and thinking machines will have to reach beyond current engineering trends in both what they learn, and how they learn it...
November 24, 2016: Behavioral and Brain Sciences
https://www.readbyqxmd.com/read/27875640/an-untold-story-the-important-contributions-of-muslim-scholars-for-the-understanding-of-human-anatomy
#15
REVIEW
Malak A Alghamdi, Janine M Ziermann, Rui Diogo
It is usually assumed that Galen is one of the fathers of anatomy and that between the Corpus Galenicum and the Renaissance there was no major advance in anatomical knowledge. However, it is also consensually accepted that Muslim scholars had the intellectual leadership from the 8th/9th to 13th centuries, and that they made remarkable progresses in numerous scientific fields including medicine. So, how is it possible that they did not contribute to advance human anatomy during that period? According to the dominant view Muslim scholars exclusively had a passive role: their transmission of knowledge from the Greeks to the West...
November 22, 2016: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/27875154/small-multiples-with-gaps
#16
Wouter Meulemans, Jason Dykes, Aidan Slingsby, Cagatay Turkay, Jo Wood
Small multiples enable comparison by providing different views of a single data set in a dense and aligned manner. A common frame defines each view, which varies based upon values of a conditioning variable. An increasingly popular use of this technique is to project two-dimensional locations into a gridded space (e.g. grid maps), using the underlying distribution both as the conditioning variable and to determine the grid layout. Using whitespace in this layout has the potential to carry information, especially in a geographic context...
January 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/27870090/the-dual-role-of-nfl-team-doctors
#17
Marvin Washington
Glenn Cohen, Holly Fernandez Lynch, and Christopher Deubert are right in their article "A Proposal to Address NFL Club Doctors' Conflicts of Interest and to Promote Player Trust" that the problem with the medical care rendered to National Football League players is not that the doctors are bad, but that the system in which they provide care is structured badly. We saw some of the problems this system causes last season in what happened to Case Kenum, a quarterback for the Los Angeles Rams who, despite having a possible concussion from a game injury, was allowed to continue to play, with a concussion spotter in the booth and coaches, teammates, seven game officials, and two full training staffs present...
November 2016: Hastings Center Report
https://www.readbyqxmd.com/read/27868168/use-perceptions-and-benefits-of-automotive-technologies-among-aging-drivers
#18
REVIEW
David W Eby, Lisa J Molnar, Liang Zhang, Renée M St Louis, Nicole Zanier, Lidia P Kostyniuk, Sergiu Stanciu
Advanced in-vehicle technologies have been proposed as a potential way to keep older adults driving for as long as they can safely do so, by taking into account the common declines in functional abilities experienced by older adults. The purpose of this report was to synthesize the knowledge about older drivers and advanced in-vehicle technologies, focusing on three areas: use (how older drivers use these technologies), perception (what they think about the technologies), and outcomes (the safety and/or comfort benefits of the technologies)...
December 2016: Injury Epidemiology
https://www.readbyqxmd.com/read/27867446/-so-far-it-s-been-choosing-which-side-effects-i-want-or-i-can-deal-with-a-grounded-theory-of-hiv-treatment-side-effects-among-people-living-with-hiv
#19
Marilou Gagnon, Dave Holmes
Despite the availability of new antiretroviral drugs and the simplification of treatment options, side effects continue to affect people living with HIV. In this paper, we present the findings of a grounded theory study designed to gain a critical understanding of the experience of side effects. Three main categories emerged from the data: the side effects, the experience, and the connections. The first category suggests that we need to change how we think about side effects in order to take into account the context in which they are experienced as well as the types and nature of side effects...
January 1, 2016: Aporia
https://www.readbyqxmd.com/read/27864082/individual-variation-in-intentionality-in-the-mind-wandering-state-is-reflected-in-the-integration-of-the-default-mode-fronto-parietal-and-limbic-networks
#20
Johannes Golchert, Jonathan Smallwood, Elizabeth Jefferies, Paul Seli, Julia M Huntenburg, Franziskus Liem, Mark E Lauckner, Sabine Oligschläger, Boris C Bernhardt, Arno Villringer, Daniel S Margulies
Mind-wandering has a controversial relationship with cognitive control. Existing psychological evidence supports the hypothesis that episodes of mind-wandering reflect a failure to constrain thinking to task-relevant material, as well the apparently alternative view that control can facilitate the expression of self-generated mental content. We assessed whether this apparent contradiction arises because of a failure to consider differences in the types of thoughts that occur during mind-wandering, and in particular, the associated level of intentionality...
November 15, 2016: NeuroImage
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