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hypertension, atherosclerosis, carotid intima media thickness

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https://www.readbyqxmd.com/read/28915687/features-and-risk-factors-of-carotid-atherosclerosis-in-a-population-with-high-stroke-incidence-in-china
#1
Yanqiu Zhang, Lingling Bai, Min Shi, Hongyan Lu, Yanan Wu, Jun Tu, Jingxian Ni, Jinghua Wang, Li Cao, Ping Lei, Xianjia Ning
Epidemiological studies have reported associations between traditional cardiovascular risk factors and carotid intima-media thickness (CIMT) or carotid plaque. However, definite risk factors at different phases of carotid atherosclerosis remain controversial. We aimed to explore risk factors and characteristics of carotid atherosclerosis at different stages in a low-income population with a high incidence of stroke in China. Between April 2014 and January 2015, we recruited 3789 stroke-free and cardiovascular disease-free residents aged ≥ 45 years...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28904456/association-of-serum-25-hydroxyvitamin-d-in-carotid-intima-media-thickness-a-study-from-south-india
#2
Jaydip Ray Chauduri, K Rukmini Mridula, Matapathi Umamashesh, Banda Balaraju, V C S Srinivasarao Bandaru
BACKGROUND: Abnormal carotid intima-media thickness (IMT) is a marker of carotid atherosclerosis which is a risk factor for cerebrovascular and cardiovascular diseases. Recent studies have found an association of 25-hydroxyvitamin D deficiency with abnormal carotid IMT. PURPOSE: The purpose of the study was to investigate the association of serum 25-hydroxyvitamin D levels with carotid IMT in Indian participants. MATERIALS AND METHODS: We prospectively recruited 300 participants at Yashoda Hospital, Hyderabad, during the study period between January 2012 and December 2014...
July 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28883843/plasma-soluble-cd36-carotid-intima-media-thickness-and-cognitive-function-in-patients-with-type-2-diabetes
#3
Xiaozhen Jiang, Xiaohui Zhao, Ruihua Chen, Quan Jiang, Bin Zhou
INTRODUCTION: Diabetes and atherosclerosis are both risk factors of cognitive deficits. Scavenger receptor CD36 is associated with increasing risk of diabetes and atherosclerosis, and may play a role in cognitive deficits. The aim of this study is to determine the correlations of plasma soluble CD36 concentrations with carotid intima-media thickness (IMT) and cognitive function in patients with type 2 diabetes. MATERIAL AND METHODS: We determined the levels of soluble CD36 (sCD36), blood lipids, fasting blood glucose, glycosylated hemoglobin, carotid atherosclerosis as IMT, cognitive function by the Montreal Cognitive Assessment (MoCA) scoring system, and other clinical characteristics in 357 patients with type 2 diabetes...
August 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28852407/the-association-between-bone-quality-and-atherosclerosis-results-from-two-large-population-based-studies
#4
V Lange, M Dörr, U Schminke, H Völzke, M Nauck, H Wallaschofski, A Hannemann
OBJECTIVE: It is highly debated whether associations between osteoporosis and atherosclerosis are independent of cardiovascular risk factors. We aimed to explore the associations between quantitative ultrasound (QUS) parameters at the heel with the carotid artery intima-media thickness (IMT), the presence of carotid artery plaques, and the ankle-brachial index (ABI). METHODS: The study population comprised 5680 men and women aged 20-93 years from two population-based cohort studies: Study of Health in Pomerania (SHIP) and SHIP-Trend...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28816229/plasma-expression-level-of-mirna-let-7-is-positively-correlated-with-carotid-intima-media-thickness-in-patients-with-essential-hypertension
#5
Y-Q Huang, C Huang, J-Y Chen, J Li, Y-Q Feng
MicroRNAs (miRNA, miR) play vital part in the pathophysiology of arterial remodeling in hypertension patients, and are increasingly becoming novel biomarkers in cardiovascular disease. The study was designed to evaluate the correlation between let-7 expression level and subclinical atherosclerosis in untreated patients with newly diagnosed essential hypertension. We assessed 240 participants including 60 healthy volunteers with normal carotid intima-media thickness (nCIMT), 60 healthy volunteers with increased CIMT (iCIMT), 60 hypertension patients with nCIMT and 60 hypertension patients with iCIMT...
August 17, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28802699/relationship-between-limited-joint-mobility-of-hand-and-carotid-atherosclerosis-in-patients-with-type-2-diabetes
#6
Yusuke Mineoka, Michiyo Ishii, Yoshitaka Hashimoto, Muhei Tanaka, Naoto Nakamura, Yasukazu Katsumi, Motohide Isono, Michiaki Fukui
AIM: Limited joint mobility (LJM) of hand, which is one of a complication of diabetic hand, has a close association with diabetic microangiopathy. However, it remains to be elucidated about the relationships between LJM of hand and subclinical atherosclerosis in patients with type 2 diabetes. Therefore, we conducted a cross-sectional study to evaluate the relationships between LJM of hand and carotid intima-media thickness (IMT) and plaque score in patients with type 2 diabetes. METHODS: We evaluated the relationships between LJM of hand, and carotid IMT and plaque score, evaluated by carotid ultrasound examination, in 341 consecutive patients with type 2 diabetes...
July 20, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28711962/the-relation-between-hemoglobin-variability-and-carotid-intima-media-thickness-in-chronic-hemodialysis-patients
#7
Safa Ersen Ganidagli, Orcun Altunoren, Ertuğrul Erken, Ismet Onder Isık, Berivan Ganidagli, Necmi Eren, Yasemin Coskun Yavuz, Ozkan Gungor
PURPOSE: Hemoglobin variability is a common problem among hemodialysis patients. We have previously demonstrated an association between Hb variability and left ventricular mass index. In this study, we investigated a possible relation between Hb variability and carotid intima-media thickness (CIMT). METHODS: Twelve-month hemoglobin (Hb) values of 135 patients on maintenance hemodialysis were examined retrospectively. The range of 11-12 gr/dl was accepted as normal according to the KDOQI guidelines...
July 15, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28695435/evaluation-of-development-of-subclinical-atherosclerosis-in-children-with-uveitis
#8
Seçil Conkar, Suzan Güven Yılmaz, İlker Özgür Koska, Afig Berdeli, Sevgi Mir
Uveitis is a chronic inflammatory disease. Chronic inflammation has been shown to have a role in pathogenesis of atherosclerosis. Atherosclerosis is the most important risk factor of cardiovascular diseases and is shown to start as early as childhood. In this study, we investigated the presence of subclinical atherosclerosis in children with uveitis. Seventy five patients who were diagnosed as having uveitis in ophthalmology and pediatric rheumatology clinics were included in the study. Patients with hypertension, obesity, dyslipidemia, diabetes, and with history of early cardiovascular disease were excluded...
July 10, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28664622/subclinical-atherosclerosis-in-low-framingham-risk-hiv-patients
#9
Rafael León, Sergio Reus, Nicolás López, Irene Portilla, José Sánchez-Payá, Livia Giner, Vicente Boix, Esperanza Merino, Diego Torrús, Óscar Moreno, Joaquín Portilla
BACKGROUND: Pathogenesis of atherosclerosis is complex and differences between HIV-infected patients and general population cannot be completely explained by the higher prevalence of traditional cardiovascular risk factors. We aimed to analyse the association between inflammation and subclinical atherosclerosis in HIV patients with low Framingham risk score. MATERIALS AND METHODS: Case-control study. SETTING: outpatient Infectious Diseases clinic in a university hospital...
June 29, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28662159/pre-clinical-carotid-atherosclerosis-and-scd163-among-virally-suppressed-hiv-patients-in-botswana-compared-with-uninfected-controls
#10
Mosepele Mosepele, Linda C Hemphill, Walter Moloi, Sikhulile Moyo, Isaac Nkele, Joseph Makhema, Kara Bennett, Virginia A Triant, Shahin Lockman
OBJECTIVES: Human immune deficiency virus (HIV) is associated with increased cardiovascular disease (CVD) risk, yet the relationship between HIV and carotid atherosclerosis / monocyte activation among virally suppressed HIV-infected patients in sub-Saharan Africa is not well understood. METHODS: We measured traditional CVD risk factors, bilateral distal common carotid intima media thickness (cIMT), presence of carotid plaque and plasma sCD163 levels among virally suppressed HIV-infected adults and HIV-uninfected controls, in a cross-sectional study in Gaborone, Botswana...
2017: PloS One
https://www.readbyqxmd.com/read/28626161/morning-and-evening-blood-pressures-are-associated-with-intima-media-thickness-in-a-general-population%C3%A3-the-hisayama-study
#11
Satoko Sakata, Jun Hata, Masayo Fukuhara, Koji Yonemoto, Naoko Mukai, Daigo Yoshida, Hiro Kishimoto, Toshio Ohtsubo, Takanari Kitazono, Yutaka Kiyohara, Toshiharu Ninomiya
BACKGROUND: The association of morning and evening home blood pressures (HBPs) with carotid atherosclerosis has been uncertain in general populations, so we aimed to investigate it in a general Japanese population.Methods and Results:We performed a cross-sectional survey of 2,856 community-dwelling individuals aged ≥40 years to examine the association of morning and evening HBPs with carotid mean intima-media thickness (IMT). The age- and sex-adjusted geometric averages of carotid mean IMT increased significantly with increasing morning HBP (optimal: 0...
June 14, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28608454/accelerated-atherosclerosis-in-anca-associated-vasculitis
#12
I González-Suárez, J J Ríos-Blanco, J Arpa
OBJECTIVES: Cardiovascular disease, including myocardial infarction and stroke, is a major cause of mortality in ANCA-associated vasculitis (AAV). Although AAV affects small vessels, an accelerated atherosclerosis not explained by traditional cardiovascular risk factors (CVRF) has been demonstrated. We aimed to investigate the association of atherosclerosis measured by carotid intima-media thickness (CIMT) and cerebral small vessel disease in AAV-patients. MATERIALS & METHODS: Twenty-three AAV-patients in complete remission were recruited...
June 12, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/28603501/cardiac-remodeling-from-middle-age-to-senescence
#13
Mikko J Möttönen, Olavi Ukkola, Jarmo Lumme, Y Antero Kesäniemi, Heikki V Huikuri, Juha S Perkiömäki
Background: The data on cardiac remodeling outside the scope of myocardial infarction and heart failure are limited. Methods: A cohort of middle-aged hypertensive subjects with age- and gender-matched control subjects without hypertension (n = 1,045, aged 51 ± 6 years) were randomly selected for the OPERA study (Oulu Project Elucidating Risk of Atherosclerosis study). The majority of those who were still alive after more than 20 years of follow-up underwent thorough re-examinations. Results: Left ventricular mass index (LVMI) increased significantly from 106...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28585193/the-definition-and-prevalence-of-obesity-and-metabolic-syndrome
#14
REVIEW
Atilla Engin
Increase in prevalence of obesity has become a worldwide major health problem in adults, as well as among children and adolescents. Furthermore, total adiposity and truncal subcutaneous fat accumulation during adolescence are positively and independently associated with atherosclerosis at adult ages. Centrally accumulation of body fat is associated with insulin resistance, whereas distribution of body fat in a peripheral pattern is metabolically less important. Obesity is associated with a large decrease in life expectancy...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28554682/liver-and-cardiovascular-damage-in-patients-with-lean-nonalcoholic-fatty-liver-disease-and-association-with-visceral-obesity
#15
Anna Ludovica Fracanzani, Salvatore Petta, Rosa Lombardi, Giuseppina Pisano, Maurizio Russello, Dario Consonni, Vito Di Marco, Calogero Cammà, Laura Mensi, Paola Dongiovanni, Luca Valenti, Antonio Craxì, Silvia Fargion
BACKGROUND & AIMS: Lean nonalcoholic fatty liver disease (NAFLD) is defined as NAFLD that develops in patients with a body mass index (BMI) less than 25 kg/m(2). We investigated the differences between lean NAFLD and NAFLD in overweight and obese persons, factors associated with the severity of liver and cardiovascular disease, and the effects of visceral obesity. METHODS: We performed a retrospective cohort study of 669 consecutive patients with biopsy-proven NAFLD seen at 3 liver centers in Italy...
May 26, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28554006/chronic-arsenic-exposure-and-risk-of-carotid-artery-disease-the-strong-heart-study
#16
Farrah J Mateen, Maria Grau-Perez, Jonathan S Pollak, Katherine A Moon, Barbara V Howard, Jason G Umans, Lyle G Best, Kevin A Francesconi, Walter Goessler, Ciprian Crainiceanu, Eliseo Guallar, Richard B Devereux, Mary J Roman, Ana Navas-Acien
BACKGROUND: Inorganic arsenic exposure from naturally contaminated groundwater is related to vascular disease. No prospective studies have evaluated the association between arsenic and carotid atherosclerosis at low-moderate levels. We examined the association of long-term, low-moderate inorganic arsenic exposure with carotid arterial disease. METHODS: American Indians, 45-74 years old, in Arizona, Oklahoma, and North and South Dakota had arsenic concentrations (sum of inorganic and methylated species, μg/g urine creatinine) measured from baseline urine samples (1989-1991)...
August 2017: Environmental Research
https://www.readbyqxmd.com/read/28543093/relationship-between-carotid-atherosclerosis-and-coronary-artery-calcification-in-asymptomatic-diabetic-patients-a-prospective-multicenter-study
#17
Anand Jeevarethinam, Shreenidhi Venuraju, Alain Dumo, Sherezade Ruano, Vishal S Mehta, Miranda Rosenthal, Devaki Nair, Mark Cohen, Daniel Darko, Avijit Lahiri, Roby Rakhit
BACKGROUND: The value of screening sub-clinical atherosclerosis in asymptomatic patients with type 2 diabetes mellitus (T2DM) remains controversial. HYPOTHESIS: An integrated model incorporating carotid intima-media thickness (CIMT) and carotid plaque with traditional risk factors can be used to predict prevalence and severity of coronary artery calcification in asymptomatic T2DM patients. METHODS: A cohort of 262 asymptomatic T2DM patients were prospectively studied with carotid ultrasound to evaluate CIMT and carotid plaque and also a computed tomography coronary artery calcium (CT-CAC) scan...
May 25, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28508856/association-between-carotid-plaque-score-and-microvascular-complications-of-type-2-diabetes
#18
Wojciech Bartman, Katarzyna Nabrdalik, Hanna Kwiendacz, Tomasz Sawczyn, Andrzej Tomasik, Krystyna Pierzchała, Monika Adamczyk-Sowa, Agnieszka Machowska-Majchrzak, Beata Łabuz-Roszak, Władysław Grzeszczak, Janusz Gumprecht
INTRODUCTION    According to the "common soil" hypothesis, diabetic microangiopathy and macroangiopathy have a similar pathophysiological background. It has been well documented that carotid artery atherosclerosis in patients with type 2 diabetes is associated with cardiovascular complications; however, it remains unclear whether there is a similar association for microvascular complications. OBJECTIVES    We investigated whether the carotid plaque score and the carotid intima-media thickness (IMT) are associated with macroangiopathic and microangiopathic complications of type 2 diabetes...
June 30, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/28498145/brief-report-progression-of-atherosclerosis-in-hiv-infected-individuals-prospective-data-from-an-asian-cohort
#19
Grace Lui, Ronald C W Ma, Ping Chook, Chun-Kwok Wong, Claudia H T Tam, Michael H M Chan, Shui-Shan Lee, Rity Y K Wong, Catherine S K Cheung, Kin-Wing Choi, Ping-Chung Leung, Ka-Hing Wong, Kenny C W Chan, Nelson Lee
BACKGROUND: The magnitude and risk factors of progression of atherosclerosis in Asian HIV-infected individuals were unknown. This study aimed to evaluate: (1) the rate of progression of atherosclerosis in HIV-infected individuals, and (2) metabolic and inflammatory parameters that may predict atherosclerosis progression in HIV-infected individuals in an Asian cohort. SETTING: A prospective, longitudinal study was performed among adults attending an HIV Metabolic clinic in Hong Kong...
June 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28455826/subendocardial-viability-ratio-in-patients-with-rheumatoid-arthritis-comparison-with-healthy-controls-and-identification-of-prognostic-factors
#20
Panagiota Anyfanti, Areti Triantafyllou, Eugenia Gkaliagkousi, Georgios Triantafyllou, Nikolaos Koletsos, Sophia Chatzimichailidou, Panagiotis Panagopoulos, Ioannis Botis, Spyros Aslanidis, Stella Douma
Cardiac involvement is common in rheumatoid arthritis. Subendocardial viability ratio (SEVR) is a non-invasive measure of microvascular coronary perfusion, yet it remains unclear whether it is affected in rheumatoid arthritis patients. We additionally sought predictors of SEVR in rheumatoid arthritis among a wide range of disease-related parameters, cardiac and hemodynamic factors, and markers of atherosclerosis, arteriosclerosis, and endothelial dysfunction. SEVR was estimated in rheumatoid arthritis patients and healthy controls by applanation tonometry, which was also used to evaluate arterial stiffness (pulse wave velocity and augmentation index)...
June 2017: Clinical Rheumatology
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