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https://www.readbyqxmd.com/read/28223540/akirin2-promotes-slow-myosin-heavy-chain-expression-by-can-nfatc1-signaling-in-porcine-skeletal-muscle-satellite-cells
#1
Xiaoling Chen, Yanliu Luo, Zhiqing Huang, Guangmang Liu, Hua Zhao
The objective of this study was to evaluate the effect of Akirin2 on slow myosin heavy chain (slow MyHC, MyHC I) gene expression and its molecular mechanisms. In this study, we showed that the protein expression of Akirin2 in pig slow oxidative Psoas major muscle is higher than that in fast glycolytic tibialis anterior muscle, suggesting that Akirin2 may play a role in myofiber typing. Knockdown of Akirin2 decreased the MyHC I expression and the calcineurin (CaN) activity, and also decreased the expressions of NFATc1 and MCIP1...
February 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28215519/repeatability-of-computerized-tomography-based-anthropomorphic-measurements-of-frailty-in-patients-with-pulmonary-fibrosis-undergoing-lung-transplantation
#2
Taylor McClellan, Brian C Allen, Matthew Kappus, Lubna Bhatti, Randa A Dafalla, Laurie D Snyder, Mustafa R Bashir
PURPOSE: To determine interreader and intrareader repeatability and correlations among measurements of computerized tomography-based anthropomorphic measurements in patients with pulmonary fibrosis undergoing lung transplantation. METHODS: This was an institutional review board-approved, Health Insurance Portability and Accountability Act-compliant retrospective study of 23 randomly selected subjects (19 male and 4 female; median age = 69 years; range: 66-77 years) with idiopathic pulmonary fibrosis undergoing pulmonary transplantation, who had also undergone preoperative thoracoabdominal computerized tomography...
December 29, 2016: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28215411/impact-of-skeletal-muscle-mass-on-long-term-adverse-cardiovascular-outcomes-in-patients-with-chronic-kidney%C3%A2-disease
#3
Kazuhiro Harada, Susumu Suzuki, Hideki Ishii, Toshijiro Aoki, Kenshi Hirayama, Yohei Shibata, Yosuke Negishi, Takuya Sumi, Kazuhiro Kawashima, Ayako Kunimura, Yusaku Shimbo, Yosuke Tatami, Toshiki Kawamiya, Dai Yamamoto, Ryota Morimoto, Yoshinari Yasuda, Toyoaki Murohara
Sarcopenia, defined as skeletal muscle loss and dysfunction, is attracting considerable attention as a novel risk factor for cardiovascular events. Although the loss of skeletal muscle is common in chronic kidney disease (CKD) patients, the relation between sarcopenia and cardiovascular events in CKD patients is not well defined. Therefore, we aimed to investigate the relation between skeletal muscle mass and major adverse cardiovascular events (MACE) in CKD patients. We enrolled 266 asymptomatic CKD patients (median estimated glomerular filtration rate: 36...
January 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28210944/postoperative-imaging-in-arthroscopic-hip-surgery
#4
REVIEW
F Di Pietto, V Chianca, R de Ritis, E Cesarano, A Reginelli, A Barile, M Zappia, L Ginolfi
Arthroscopic surgery of the hip, compared to that of the knee or the shoulder, has only recently been developed in any significant way. Current indications for arthroscopic surgery of the hip include: diagnosis and treatment of lesions symptomatic of the acetabular labrum, femoroacetabular impingement (FAI), chondral lesions, joint infections, lesions of the teres ligament, impingement of the psoas tendon, pathology of the peritrochanteric space, external snapping hip (coxa saltans), and traumatic and atraumatic instability...
February 16, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28202301/preoperative-assessment-of-the-ureter-with-dual-phase-contrast-enhanced-computed-tomography-for-lateral-lumbar-interbody-fusion-procedures
#5
Shunsuke Fujibayashi, Bungo Otsuki, Hiroaki Kimura, Shimei Tanida, Kazutaka Masamoto, Shuichi Matsuda
BACKGROUND: Performing the minimally invasive lateral lumbar interbody fusion (LIF), such as the extreme lateral interbody fusion (XLIF) and oblique lateral interbody fusion (OLIF), through a retroperitoneal approach has become increasingly popular. Although urological injury is a major complication of LIF, the anatomical location of the ureter and its risk of injury have not been assessed. The purpose of this study was to evaluate the efficacy of dual-phase contrast-enhanced computed tomography for assessing the location of the ureter and risk of its injury in consecutive LIF cases...
February 12, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28184274/cerebrospinal-fluid-infection-after-lumbar-nerve-root-steroid-injection-a-case-report
#6
Kwan-Sub Kim, Young-Ki Kim, Seong-Su Kim, Sung Min Shim, Hae Jun Cho
A 45-year-old woman was admitted due to severe headache and neck stiffness. She had visited a local clinic for back pain and received a lumbar nerve root steroid injection 10 days before admission. Computed tomography and magnetic resonance imaging showed psoas abscess, pneumocephalus, and subdural hygroma. She was diagnosed with psoas abscess and meningitis. The abscess and external ventricle were drained, and antibiotics were administered. Unfortunately, the patient died on hospital day 19 due to diffuse leptomeningitis...
February 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28181820/preoperative-volume-rather-than-area-of-skeletal-muscle-is-a-better-predictor-for-postoperative-risks-for-respiratory-complications-in-living-donor-liver-transplantation
#7
Yuki Wada, Tamotsu Kamishima, Tsuyoshi Shimamura, Norio Kawamura, Kenichiro Yamashita, Kenneth Sutherland, Hiroshi Takeda
OBJECTIVES: To demonstrate the superiority of total psoas volume (TPV) over total psoas area (TPA) in terms of predicting postoperative complications in living-donor liver transplantation (LDLT). METHODS: TPA and TPV were assessed in 32 recipients who underwent computed tomography (CT) before LDLT. TPA was measured using an axial CT image at the level of the upper margin of the 4th lumbar vertebral body. TPV was calculated using all the CT images from the muscle origin through the level of pubic symphysis...
February 9, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28180981/does-pre-operative-magnetic-resonance-imaging-of-the-lumbar-multifidus-muscle-predict-clinical-outcomes-following-lumbar-spinal-decompression-for-symptomatic-spinal-stenosis
#8
Mario G T Zotti, F Vilas Boas, T Clifton, M Piche, W W Yoon, B J C Freeman
PURPOSE: To investigate whether pre-operative magnetic resonance imaging (MRI) of the lumbar multifidus muscle (LMM) would predict clinical outcomes following lumbar spinal decompression for symptomatic spinal stenosis. METHODS: A prospective cohort of patients with symptomatic neurogenic claudication, documented spinal stenosis on pre-operative MRI underwent spinal decompression. All subjects completed standardised outcome measures (Core Outcome Measures Index (COMI), Oswestry Disability Index (ODI v2...
February 8, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28177738/sorbitol-increases-muscle-glucose-uptake-ex-vivo-and-inhibits-intestinal-glucose-absorption-ex-vivo-and-in-normal-and-type-2-diabetic-rats
#9
Chika I Chukwuma, Md Shahidul Islam
Previous studies have suggested that sorbitol, a known polyol sweetener possesses glycemic control potentials. However, the effect of sorbitol on intestinal glucose absorption and muscle glucose uptake still remains elusive. The present study investigated the effects of sorbitol on intestinal glucose absorption and muscle glucose uptake as possible anti-hyperglycemic or glycemic control potentials using <i>ex vivo </i>and in vivo experimental models. Sorbitol (2.5% to 20%) inhibited glucose absorption in isolated rat jejuna (IC<sub>50</sub> = 14...
December 12, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28158957/trunk-muscle-characteristics-of-the-multifidi-erector-spinae-psoas-and-quadratus-lumborum-in-older-adults-with-and-without-chronic-low-back-pain
#10
J Megan Sions, James M Elliott, Ryan T Pohlig, Gregory E Hicks
Study Design Cross-sectional study. Background Muscle support for the trunk is provided by the multifidi, erector spinae, psoas, and quadratus lumborum. Trunk muscle characteristics may be altered with aging and/or chronic LBP. To date, most trunk muscle research has been conducted among younger adults. Given age-related muscle changes, i.e. reduced size and increased intramuscular fat, studies are needed in older adults, including comparisons of older adults with and without LBP. Objective To determine if there are differences in trunk muscle characteristics between older adults with and without chronic low back pain (LBP), while controlling for age, sex, and body mass index...
February 3, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28154824/ultrasound-guided-quadratus-lumborum-block-an-updated-review-of-anatomy-and-techniques
#11
REVIEW
Hironobu Ueshima, Hiroshi Otake, Jui-An Lin
Purpose of Review. Since the original publication on the quadratus lumborum (QL) block, the technique has evolved significantly during the last decade. This review highlights recent advances in various approaches for administering the QL block and proposes directions for future research. Recent Findings. The QL block findings continue to become clearer. We now understand that the QL block has several approach methods (anterior, lateral, posterior, and intramuscular) and the spread of local anesthetic varies with each approach...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28149936/change-in-psoas-muscle-volume-as-a-predictor-of-outcomes-in-patients-treated-with-chemotherapy-and-radical-cystectomy-for-muscle-invasive-bladder-cancer
#12
Homayoun Zargar, Nima Almassi, Evan Kovac, Cesar Ercole, Erick Remer, Brian Rini, Andrew Stephenson, Jorge A Garcia, Petros Grivas
Objective: Sarcopenia, or the age-related loss of skeletal muscle mass and function, has been investigated as a potential marker of adverse outcomes among surgical patients. Our aim was to assess for changes in psoas muscle volume (PMV) following administration of neoadjuvant chemotherapy (NAC) in patients with bladder cancer and to examine whether changes in PMV following NAC are predictive of perioperative complications, pathologic response or survival. Methods: During the period of 2009-2013, patients undergoing NAC and radical cystectomy (RC) at our institution with pre and post NAC cross sectional images available were included...
January 27, 2017: Bladder Cancer
https://www.readbyqxmd.com/read/28149744/arthroscopic-psoas-management-techniques-for-psoas-preservation-and-psoas-tenotomy
#13
Andrea M Spiker, Ryan M Degen, Christopher L Camp, Struan H Coleman
The iliopsoas tendon is an important dynamic stabilizer of the hip joint, and it should be carefully identified and preserved during routine hip arthroscopy. However, it may also be a source of hip pain manifesting as iliopsoas tendinitis or a snapping hip or contributing to the development of labral pathology caused by psoas impingement. In the appropriately indicated, refractory cases of iliopsoas-related hip pain, surgical intervention in the form of an iliopsoas tenotomy at the level of the labrum can result in reliable pain relief...
December 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28149665/seronegative-brucellosis-of-the-spine-a-case-of-psoas-abscess-secondary-to-brucellar-spondylitis
#14
Gülnur Taşcı Bozbaş, Ayşe İyiyapıcı Ünübol, Gülcan Gürer
Brucellosis is an infectious disease that affects many organ systems. Osteoarticular involvement, especially spondylitis, is the most common complication of brucellosis, but psoas abscess is very rare. Serological tests at diagnosis of the disease are very valuable and most widely used. Herein, we report a case of psoas abscess secondary to brucellar spondylitis. In this case, interestingly, the serological test results were negative, and the diagnosis could be made by abscess culture. In patients, particularly those who live in areas endemic for brucellosis, as in our case, it should be kept in mind that a negative serological test result should not exclude the diagnosis of brucellosis...
December 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28122223/the-relaxation-properties-of-myofibrils-are-compromised-by-amino-acids-that-stabilize-%C3%AE-tropomyosin
#15
Beatrice Scellini, Nicoletta Piroddi, Alexander M Matyushenko, Dmitrii I Levitsky, Corrado Poggesi, Sherwin S Lehrer, Chiara Tesi
We investigated the functional impact of α-tropomyosin (Tm) substituted with one (D137L) or two (D137L/G126R) stabilizing amino acid substitutions on the mechanical behavior of rabbit psoas skeletal myofibrils by replacing endogenous Tm and troponin (Tn) with recombinant Tm mutants and purified skeletal Tn. Force recordings from myofibrils (15°C) at saturating [Ca(2+)] showed that Tm-stabilizing substitutions did not significantly affect the maximal isometric tension and the rates of force activation (kACT) and redevelopment (kTR)...
January 24, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28119773/psoas-compartment-block-for-treatment-of-motor-weakness-and-pain-following-herpes-zoster
#16
Sae Young Kim, Dong Gyeong Kim, Yong Min Park, Young Hoon Jeon
Reactivation of the latent varicella zoster virus in the sensory ganglion causes herpes zoster (HZ). Its characteristic symptom is a painful rash in the involved dermatome. HZ-induced motor weakness is rare and is usually resolved within one year of the onset, but some patients permanently experience motor dysfunction. Epidural steroid administration, with antiviral therapy, can be effective in treating pain from HZ and preventing postherpetic neuralgia. But an epidural block is contraindicated in patients receiving thromboprophylaxis...
January 2017: Korean Journal of Pain
https://www.readbyqxmd.com/read/28116254/bilateral-prosthetic-hip-joint-infections-associated-with-a-psoas-abscess-a-case-report
#17
G D Rajitha Gunaratne, Riaz J K Khan, Cynthia Tan, Clayton Golledge
INTRODUCTION: Psoas abscess is a recognized but under-diagnosed complication of prosthetic hip joint infections. CASE REPORT: We report a case of a 68-year-old man with right and left hip arthroplasties performed 22 and 14 years ago, respectively, who presented with non-specific symptoms and was subsequently diagnosed with left psoas abscess on CT scan. Drainage of the psoas abscess was complicated by the formation of a discharging sinus connected to the left hip...
July 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28097658/segmental-fibre-type-composition-of-the-rat-iliopsoas-muscle
#18
Hrvoje Vlahovic, Ksenija Bazdaric, Verner Marijancic, Tamara Soic-Vranic, Daniela Malnar, Juraj Arbanas
The iliopsoas of the rat is composed of two muscles - the psoas major muscle and the iliacus muscle. The psoas major muscle arises from all the lumbar vertebrae and the iliacus muscle from the fifth and sixth lumbar vertebrae and ilium. Their common insertion point is the lesser trochanter of the femur, and their common action is the lateral rotation of the femur and flexion of the hip joint. Unlike humans, the rat is a quadruped and only occasionally rises up on its hind legs. Therefore, it is expected that the fibre type composition of the rat iliopsoas muscle will be different than that of humans...
January 18, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28097242/anterior-to-psoas-atp-fusion-of-the-lumbar-spine-evolution-of-a-technique-facilitated-by-changes-in-equipment
#19
Cristian Gragnaniello, Kevin Seex
BACKGROUND: Lateral interbody cages have been proven useful in spinal fusions. Spanning both lateral cortical rims while sparing the Anterior Longitudinal Ligament, the lateral interbody cages restore and maintain disc height while adding stability prior to supplemental fixation. The standard approach for their insertion is by a 90-degree lateral transpsoas method. This is relatively bloodless compared to other techniques although has its limitations, requiring neuro-monitoring and being, at times, very difficult at L4/5 due to iliac crest obstruction or an anterior plexus position...
December 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28089666/mini-open-oblique-lumbar-interbody-fusion-olif-approach-for-multi-level-discectomy-and-fusion-involving-l5-s1-preliminary-experience
#20
Fahed Zairi, Tarek P Sunna, Harrison J Westwick, Alexander G Weil, Zhi Wang, Ghassan Boubez, Daniel Shedid
STUDY DESIGN: Technical description and single institution retrospective case series OBJECTIVE: Evaluate technical feasibility and evaluate complications of mini open retroperitoneal oblique lumbar interbody fusion (OLIF) at the L5-S1 level. SUMMARY OF BACKGROUND: The mini open retroperitoneal oblique lumbar interbody fusion (OLIF) approach was first described in 2012 as a surgical approach to achieve spinal fusion while limiting invasiveness of the exposure to the anterior lumbar spine...
January 12, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
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