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https://www.readbyqxmd.com/read/28340178/morphometric-covariation-between-palatal-shape-and-skeletal-pattern-in-class-ii-growing-subjects
#1
Valeria Paoloni, Roberta Lione, Francesca Farisco, Demetrios J Halazonetis, Lorenzo Franchi, Paola Cozza
Objectives: To evaluate the patterns of covariation between palatal and craniofacial morphology in Class II subjects in the early mixed dentition by means of geometric morphometrics. Methods: A cross-sectional sample of 85 Class II subjects (44 females, 41 males; mean age 8.7 years ± 0.8) was collected retrospectively according to the following inclusion criteria: European ancestry (white), Class II skeletal relationship, Class II division 1 dental relationship, early mixed dentition, and prepubertal skeletal maturation...
March 14, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28333647/automatic-choroidal-layer-segmentation-using-markov-random-field-and-level-set-method
#2
Chuang Wang, Yongmin Li, Ya Xing Wang
The choroid is an important vascular layer that supplies oxygen and nourishment to the retina. The changes in thickness of the choroid have been hypothesised to relate to a number of retinal diseases in the pathophysiology. In this work, an automatic method is proposed for segmenting the choroidal layer from macular images by using the level set framework. The 3D nonlinear anisotropic diffusion filter is used to remove all the OCT imaging artifacts including the speckle noise and to enhance the contrast. The distance regularisation and edge constraint terms are embedded into the level set method to avoid the irregular and small regions and keep information about the boundary between the choroid and sclera...
March 20, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28333394/socket-shield-technique-for-immediate-implant-placement-clinical-radiographic-and-volumetric-data-after-5%C3%A2-years
#3
Daniel Bäumer, Otto Zuhr, Stephan Rebele, Markus Hürzeler
OBJECTIVES: Implant placement immediately after tooth extraction is often accompanied by resorption of surrounding tissues. A clinical technique was developed where the buccal portion of the root is retained to preserve the periodontal ligament and bundle bone. This technique is based on animal studies showing the potential to preserve the facial tissues utilizing this approach. The purpose of this study was to gain more insight regarding the safety of the technique with regard to biological and implant-related long-term complications and to observe the clinical appearance of the peri-implant tissues...
March 23, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28331907/brace-technology-thematic-series-the-3d-rigo-ch%C3%A3%C2%AAneau-type-brace
#4
Manuel Rigo, Mina Jelačić
BACKGROUND: Chêneau and Matthias introduced in 1979 a brace concept inspired in casting. The brace was initially named "CTM" from Chêneau-Toulouse-Münster. The name "CTM" is still popular in France but "Chêneau-type brace" is its common name in the rest of the world. Principles to construct this brace were originally based on anatomical descriptions rather than biomechanics, and its standard is poor. METHODS: This paper follows the format of the "Brace technology thematic series...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28327775/nanospherical-solid-electrolyte-interface-layer-formation-in-binder-free-carbon-nanotube-aerogel-si-nanohybrids-to-provide-lithium-ion-battery-anodes-with-a-long-cycle-life-and-high-capacity
#5
Hyung Cheoul Shim, Ilhwan Kim, Chang-Su Woo, Hoo-Jeong Lee, Seungmin Hyun
Silicon anodes for lithium ion batteries (LiBs) have been attracting considerable attention due to a theoretical capacity up to about 10 times higher than that of conventional graphite. However, huge volume expansion during the cycle causes cracks in the silicon, resulting in the degradation of cycling performance and eventual failure. Moreover, low electrical conductivity and an unstable solid electrolyte interface (SEI) layer resulting from repeated changes in volume still block the next step forward for the commercialization of the silicon material...
March 22, 2017: Nanoscale
https://www.readbyqxmd.com/read/28294206/evaluation-of-accuracy-and-repeatability-using-cbct-and-a-dental-scanner-by-means-of-3d-software
#6
So-Ri Kim, Chong-Myeong Kim, Il-Do Jeong, Woong-Chul Kim, Hae-Young Kim, Ji-Hwan Kim
OBJECTIVE: The objective of the present study was to compare and evaluate the accuracy of three-dimensional (3D) image data acquired from cone beam computed tomography (CBCT) and a dental scanner using 3D software. MATERIALS AND METHODS: After selecting the full-arch forms of the maxilla and mandible as the master cast, the master cast was scanned via a high-precision optical scanner for use as master model data. The model was scanned 12 times each using CBCT and a dental scanner...
2017: International Journal of Computerized Dentistry
https://www.readbyqxmd.com/read/28277889/soft-hydrogels-featuring-in-depth-surface-density-gradients-for-the-simple-establishment-of-3d-tissue-models-for-screening-applications
#7
Ning Zhang, Vincent Milleret, Greta Thompson-Steckel, Ning-Ping Huang, János Vörös, Benjamin R Simona, Martin Ehrbar
Three-dimensional (3D) cell culture models are gaining increasing interest for use in drug development pipelines due to their closer resemblance to human tissues. Hydrogels are the first-choice class of materials to recreate in vitro the 3D extra-cellular matrix (ECM) environment, important in studying cell-ECM interactions and 3D cellular organization and leading to physiologically relevant in vitro tissue models. Here we propose a novel hydrogel platform consisting of a 96-well plate containing pre-cast synthetic PEG-based hydrogels for the simple establishment of 3D (co-)culture systems without the need for the standard encapsulation method...
March 1, 2017: SLAS Discov
https://www.readbyqxmd.com/read/28274480/use-of-intraoral-scanning-and-3-dimensional-printing-in-the-fabrication-of-a-removable-partial-denture-for-a-patient-with-limited-mouth-opening
#8
Jiang Wu, Yan Li, Yumei Zhang
BACKGROUND AND OVERVIEW: When treating patients with severely limited mouth openings, it is difficult for the dentist to obtain an impression and fabricate a removable partial denture (RPD) by using traditional methods. Intraoral scanning, computer-aided design, and 3-dimensional (3D) printing have provided alternative methods for fabricating dental prostheses. CASE DESCRIPTION: The authors present a case in which they aimed to improve the efficiency and quality of fabricating an RPD framework by integrating the technologies of intraoral scanning, computer-aided design, and 3D printing...
March 5, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28273884/2d-qsar-and-3d-qsar-comsia-studies-on-a-series-of-r-2-2-1h-indol-2-yl-ethyl-amino-1-phenylethan-1-ol-with-human-%C3%AE-%C3%A2-adrenergic-activity
#9
Gastón Apablaza, Luisa Montoya, Cesar Morales-Verdejo, Marco Mellado, Mauricio Cuellar, Carlos F Lagos, Jorge Soto-Delgado, Hery Chung, Carlos David Pessoa-Mahana, Jaime Mella
The β₃ adrenergic receptor is raising as an important drug target for the treatment of pathologies such as diabetes, obesity, depression, and cardiac diseases among others. Several attempts to obtain selective and high affinity ligands have been made. Currently, Mirabegron is the only available drug on the market that targets this receptor approved for the treatment of overactive bladder. However, the FDA (Food and Drug Administration) in USA and the MHRA (Medicines and Healthcare products Regulatory Agency) in UK have made reports of potentially life-threatening side effects associated with the administration of Mirabegron, casting doubts on the continuity of this compound...
March 5, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28267815/digital-design-and-fabrication-of-surgical-obturators-based-only-on-preoperative-computed-tomography-data
#10
Jeff Rodney, Ivan Chicchon
This article describes the digital fabrication of a surgical obturator (SO) using only computed tomography (CT) data from the tumor area. This procedure is a departure from the traditional method of making an impression and obtaining a patient cast prior to surgery to allow for SO fabrication. The present approach allows for a virtual resection based on the patient's CT image; the SO is digitally designed with animation software and fabricated by 3D printing. The SO is relined with a denture reliner at the time of surgery to complete the obturation of the maxillectomy defect...
March 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/28267500/formulation-of-olfactory-targeted-microparticles-with-tamarind-seed-polysaccharide-to-improve-nose-to-brain-transport-of-drugs
#11
Sasi B Yarragudi, Robert Richter, Helen Lee, Greg F Walker, Andrew N Clarkson, Haribalan Kumar, Shakila B Rizwan
Targeted delivery and retention of drug formulations in the olfactory mucosa, the target site for nose-to-brain drug absorption is a major challenge due to the geometrical complexity of the nose and nasal clearance. Recent modelling data indicates that 10μm-sized microparticles show maximum deposition in the olfactory mucosa. In the present study we tested the hypothesis that 10μm-sized mucoadhesive microparticles would preferentially deposit on, and increase retention of drug on, the olfactory mucosa in a novel 3D-printed human nasal-replica cast under simulated breathing...
May 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28249216/three-dimensional-analysis-of-the-uniqueness-of-the-anterior-dentition-in-orthodontically-treated-patients-and-twins
#12
A Franco, G Willems, P H C Souza, O M Tanaka, W Coucke, P Thevissen
Dental uniqueness can be proven if no perfect match in pair-wise morphological comparisons of human dentitions is detected. Establishing these comparisons in a worldwide random population is practically unfeasible due to the need for a large and representative sample size. Sample stratification is an option to reduce sample size. The present study investigated the uniqueness of the human dentition in randomly selected subjects (Group 1), orthodontically treated patients (Group 2), twins (Group 3), and orthodontically treated twins (Group 4) in comparison with a threshold control sample of identical dentitions (Group 5)...
February 26, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28243866/measuring-3d-orthodontic-actions-to-guide-clinical-treatments-involving-coil-springs-and-miniscrews
#13
Margherita Mencattelli, Elisa Donati, Pasqua Spinelli, Massimo Cultrone, Cesare Luzi, Daniele Cantarella, Cesare Stefanini
The understanding of the phenomena at the base of tooth movement, due to orthodontic therapy, is an ambitious topic especially with regard to the "optimal forces" able to move teeth without causing irreversible tissue damages. To this aim, a measuring platform for detecting 3D orthodontic actions has been developed. It consists of customized load cells and dedicated acquisition electronics. The force sensors are able to detect, simultaneously and independently of each other, the six orthodontic components which a tooth is affected by...
March 2017: Biomedical Microdevices
https://www.readbyqxmd.com/read/28230188/3d-time-lapse-imaging-and-quantification-of-mitochondrial-dynamics
#14
Miguel Sison, Sabyasachi Chakrabortty, Jérôme Extermann, Amir Nahas, Paul James Marchand, Antonio Lopez, Tanja Weil, Theo Lasser
We present a 3D time-lapse imaging method for monitoring mitochondrial dynamics in living HeLa cells based on photothermal optical coherence microscopy and using novel surface functionalization of gold nanoparticles. The biocompatible protein-based biopolymer coating contains multiple functional groups which impart better cellular uptake and mitochondria targeting efficiency. The high stability of the gold nanoparticles allows continuous imaging over an extended time up to 3000 seconds without significant cell damage...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28228173/optimization-of-vascular-casting-for-three-dimensional-fluorescence-cryo-imaging-of-collateral-vessels-in-the-ischemic-rat-hindlimb
#15
Janina C V Schwarz, Monique G J T B van Lier, Erik N T P Bakker, Judith de Vos, Jos A E Spaan, Ed VanBavel, Maria Siebes
Development of collateral vessels, arteriogenesis, may protect against tissue ischemia, however, quantitative data on this process remain scarce. We have developed a technique for replicating the entire arterial network of ischemic rat hindlimbs in three dimensions (3D) based on vascular casting and automated sequential cryo-imaging. Various dilutions of Batson's No. 17 with methyl methacrylate were evaluated in healthy rats, with further protocol optimization in ischemic rats. Penetration of the resin into the vascular network greatly depended on dilution; the total length of casted vessels below 75 µm was 13-fold higher at 50% dilution compared with the 10% dilution...
February 2017: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/28222869/accuracy-evaluation-of-intraoral-optical-impressions-a-clinical-study-using-a-reference-appliance
#16
Mohammad A Atieh, André V Ritter, Ching-Chang Ko, Ibrahim Duqum
STATEMENT OF PROBLEM: Trueness and precision are used to evaluate the accuracy of intraoral optical impressions. Although the in vivo precision of intraoral optical impressions has been reported, in vivo trueness has not been evaluated because of limitations in the available protocols. PURPOSE: The purpose of this clinical study was to compare the accuracy (trueness and precision) of optical and conventional impressions by using a novel study design. MATERIAL AND METHODS: Five study participants consented and were enrolled...
February 17, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28219649/a-novel-approach-to-segmentation-and-measurement-of-medical-image-using-level-set-methods
#17
Yao-Tien Chen
The study proposes a novel approach for segmentation and visualization plus value-added surface area and volume measurements for brain medical image analysis. The proposed method contains edge detection and Bayesian based level set segmentation, surface and volume rendering, and surface area and volume measurements for 3D objects of interest (i.e., brain tumor, brain tissue, or whole brain). Two extensions based on edge detection and Bayesian level set are first used to segment 3D objects. Ray casting and a modified marching cubes algorithm are then adopted to facilitate volume and surface visualization of medical-image dataset...
February 17, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28218557/scandcleft-randomised-trials-of-primary-surgery-for-unilateral-cleft-lip-and-palate-7-occlusion-in-5-year-olds-according-to-the-huddart-and-bodenham-index
#18
Agneta Karsten, Agneta Marcusson, Kirsti Hurmerinta, Arja Heliövaara, Annelise Küseler, Pål Skaare, Haydn Bellardie, Elisabeth Rønning, William Shaw, Kirsten Mølsted, Paul Sæle, Eli Brinck, Sara Rizell, Midia Najal Chalier, Philip Eyres, Gunvor Semb
BACKGROUND AND AIM: Good dentofacial development and good occlusion are main goals in the treatment of UCLP. The aim was to evaluate dental occlusion at age 5 years with the Huddart and Bodenham index after four different protocols of primary surgery for UCLP. DESIGN: Three parallel randomised controlled trials were undertaken as an international multicentre study by 10 cleft teams in five countries: Denmark, Finland, Sweden, Norway, and the UK. METHODS: Three different surgical procedures for primary palatal repair (Arms B, C, and D) were tested against a common procedure (Arm A) in the total cohort of 448 children born with non-syndromic UCLP...
February 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28203007/-diagnossis-and-treatment-of-complicated-anterior-teeth-esthetic-defects-by-combination-of-whole-process-digital-esthetic-rehabilitation-with-periodontic-surgery
#19
Z Li, Y S Liu, H Q Ye, Y S Liu, W J Hu, Y S Zhou
OBJECTIVE: To explore a new method of whole-process digital esthetic prosthodontic rehabilitation combined with periodontic surgery for complicated anterior teeth esthetic defects accompanied by soft tissue morphology, to provide an alternative choice for solving this problem under the guidance of three-dimensional (3D) printing digital dental model and surgical guide, thus completing periodontic surgery and digital esthetic rehabilitation of anterior teeth. METHODS: In this study, 12 patients with complicated esthetic problems accompanied by soft tissue morphology in their anterior teeth were included...
February 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28195372/conjugated-polymer-blends-for-organic-photovoltaics-rational-control-of-vertical-stratification-for-high-performance
#20
REVIEW
Yu Yan, Xuan Liu, Tao Wang
The photoactive layer of bulk-heterojunction organic solar cells, in a thickness range of tens to hundreds of nanometers, comprises phase-separated electron donors and acceptors after solution casting. The component distribution in the cross-section of these thin films is found to be heterogeneous, with electron donors or acceptors accumulated or depleted near the electrode interfaces. This vertical stratification of the photovoltaic blend influences device metrics through its impact on charge transport and recombination, and consequently plays an important role in determining the power conversion efficiency of photovoltaic devices...
February 13, 2017: Advanced Materials
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